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TargetBeta-glucuronidase(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50028013(CHEMBL3360798)
Affinity DataIC50: 900nMAssay Description:Inhibition of beta-glucuronidase (unknown origin) using p-nitrophenyl-beta-D-glucuronide substrate incubated for 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
LigandPNGBDBM50028010(CHEBI:10127 | AD-810 | CI-912 | PD-110843 | Zonegr...)
Affinity DataIC50: 1.86E+3nMAssay Description:Inhibition of carbonic anhydrase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
The University of Jordan

Curated by ChEMBL
LigandPNGBDBM50165853(CHEMBL3798658)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of EGFR in human MDA231 cells assessed as growth inhibition after 24 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2017
Entry Details Article
PubMed
LigandPNGBDBM50165853(CHEMBL3798658)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of PI3Kalpha in human HCT116 cells coexpressing PI3Kalpha H1047R mutant assessed as growth inhibition after 24 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
The University of Jordan

Curated by ChEMBL
LigandPNGBDBM50165851(CHEMBL3800448)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of EGFR in human MDA231 cells assessed as growth inhibition after 24 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
The University of Jordan

Curated by ChEMBL
LigandPNGBDBM50165852(CHEMBL3798556)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of EGFR in human MDA231 cells assessed as growth inhibition after 24 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2017
Entry Details Article
PubMed
LigandPNGBDBM50165852(CHEMBL3798556)
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of PI3Kalpha in human HCT116 cells coexpressing PI3Kalpha H1047R mutant assessed as growth inhibition after 24 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
The University of Jordan

Curated by ChEMBL
LigandPNGBDBM50165854(CHEMBL3799332)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of EGFR in human MDA231 cells assessed as growth inhibition after 24 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2017
Entry Details Article
PubMed
LigandPNGBDBM50165851(CHEMBL3800448)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of PI3Kalpha in human HCT116 cells coexpressing PI3Kalpha H1047R mutant assessed as growth inhibition after 24 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2017
Entry Details Article
PubMed
LigandPNGBDBM50165854(CHEMBL3799332)
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of PI3Kalpha in human HCT116 cells coexpressing PI3Kalpha H1047R mutant assessed as growth inhibition after 24 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
The University of Jordan

Curated by ChEMBL
LigandPNGBDBM50165849(CHEMBL3799956)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of EGFR in human MDA231 cells assessed as growth inhibition after 24 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2017
Entry Details Article
PubMed
TargetBeta-glucuronidase(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50008907(D-Saccharic Acid 1,4-Lactone)
Affinity DataIC50: 4.58E+4nMAssay Description:Inhibition of beta-glucuronidase (unknown origin) using p-nitrophenyl-beta-D-glucuronide substrate incubated for 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
The University of Jordan

Curated by ChEMBL
LigandPNGBDBM50165850(CHEMBL3799345)
Affinity DataIC50: 4.90E+4nMAssay Description:Inhibition of EGFR in human MDA231 cells assessed as growth inhibition after 24 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
The University of Jordan

Curated by ChEMBL
LigandPNGBDBM50165848(CHEMBL3797839)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of EGFR in human MDA231 cells assessed as growth inhibition after 24 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2017
Entry Details Article
PubMed
LigandPNGBDBM50165850(CHEMBL3799345)
Affinity DataIC50: 5.40E+4nMAssay Description:Inhibition of PI3Kalpha in human HCT116 cells coexpressing PI3Kalpha H1047R mutant assessed as growth inhibition after 24 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2017
Entry Details Article
PubMed
LigandPNGBDBM50165849(CHEMBL3799956)
Affinity DataIC50: 5.50E+4nMAssay Description:Inhibition of PI3Kalpha in human HCT116 cells coexpressing PI3Kalpha H1047R mutant assessed as growth inhibition after 24 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
The University of Jordan

Curated by ChEMBL
LigandPNGBDBM50165847(CHEMBL3800262)
Affinity DataIC50: 5.70E+4nMAssay Description:Inhibition of EGFR in human MDA231 cells assessed as growth inhibition after 24 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2017
Entry Details Article
PubMed
LigandPNGBDBM50165848(CHEMBL3797839)
Affinity DataIC50: 6.10E+4nMAssay Description:Inhibition of PI3Kalpha in human HCT116 cells coexpressing PI3Kalpha H1047R mutant assessed as growth inhibition after 24 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2017
Entry Details Article
PubMed
LigandPNGBDBM50165847(CHEMBL3800262)
Affinity DataIC50: 6.40E+4nMAssay Description:Inhibition of PI3Kalpha in human HCT116 cells coexpressing PI3Kalpha H1047R mutant assessed as growth inhibition after 24 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2017
Entry Details Article
PubMed
LigandPNGBDBM50028011(CHEMBL3360810)
Affinity DataIC50: 2.70E+5nMAssay Description:Inhibition of carbonic anhydrase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
LigandPNGBDBM50028012(CHEMBL3360801)
Affinity DataIC50: 4.42E+5nMAssay Description:Inhibition of carbonic anhydrase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed