Report error Found 74 with Last Name = 'mucchietto' and Initial = 'v'
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataEC50: 1.01E+4nMAssay Description:Partial agonist activity at human alpha4beta2 nAChR expressed in GH4CL cells by whole-cell patch clamp methodMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataEC50: 7.30E+4nMAssay Description:Agonist activity at human alpha4beta2 nAChR expressed in rat GH4C1 cells assessed as induction of peak current amplitude at holding potential of -70 ...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataEC50: 1.00E+3nMAssay Description:Agonist activity at human alpha4beta2 nAChR in (alpha4)2(beta2)3 stoichiometry formMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataEC50: 0.270nMAssay Description:Agonist activity at human alpha4beta2 nAChR expressed in rat GH4C1 cells assessed as induction of peak current amplitude at holding potential of -70 ...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataEC50: 1.00E+5nMAssay Description:Agonist activity at human alpha4beta2 nAChR low affinity form expressed in rat GH4C1 cells assessed as induction of peak current amplitude at holding...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataEC50: 300nMAssay Description:Agonist activity at human alpha4beta2 nAChR expressed in rat GH4C1 cells assessed as induction of peak current amplitude at holding potential of -70 ...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataEC50: 1.00E+5nMAssay Description:Agonist activity at human alpha4beta2 nAChR in (alpha4)3(beta2)2 stoichiometry formMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataEC50: 13nMAssay Description:Agonist activity at human alpha4beta2 nAChR expressed in rat GH4C1 cells assessed as induction of peak current amplitude at holding potential of -70 ...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataEC50: 400nMAssay Description:Agonist activity at human alpha4beta2 nAChR high affinity form expressed in rat GH4C1 cells assessed as induction of peak current amplitude at holdin...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataEC50: 4.40E+3nMAssay Description:Agonist activity at human alpha4beta2 nAChR expressed in rat GH4C1 cells assessed as induction of peak current amplitude at holding potential of -70 ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.80nMAssay Description:Antagonist activity at human alpha9alpha10 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh-induced channel current after 5 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Antagonist activity at human alpha9alpha10 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh-induced channel current after 5 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 6.5nMAssay Description:Antagonist activity at human alpha7 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh-induced channel current after 5 mins at -...More data for this Ligand-Target Pair
Affinity DataIC50: 6.60nMAssay Description:Antagonist activity at human alpha9alpha10 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh-induced channel current after 5 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Antagonist activity at human alpha9alpha10 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh-induced channel current after 5 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Antagonist activity at human alpha7 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh-induced channel current after 5 mins at -...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Antagonist activity at human alpha9alpha10 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh-induced channel current after 5 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Antagonist activity at human alpha9alpha10 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh-induced channel current after 5 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Antagonist activity at human alpha7 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh-induced channel current after 5 mins at -...More data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Antagonist activity at human alpha7 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh-induced channel current after 5 mins at -...More data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Antagonist activity at human alpha7 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh-induced channel current after 5 mins at -...More data for this Ligand-Target Pair
Affinity DataIC50: 92nMAssay Description:Antagonist activity at human alpha7 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh-induced channel current after 5 mins at -...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataIC50: 2.78E+3nMAssay Description:Antagonist activity at human alpha3beta4 nAChR expressed in GH4CL cells by whole-cell patch clamp methodMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataIC50: 5.36E+3nMAssay Description:Antagonist activity at human alpha4beta2 nAChR expressed in GH4CL cells by whole-cell patch clamp methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human alpha7 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh-induced channel current after 5 mins at -...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human alpha9alpha10 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh-induced channel current after 5 mi...More data for this Ligand-Target Pair
Affinity DataKi: 29nMAssay Description:Displacement of [125I]]-alpha-bungarotoxin from alpha7 nAChR in rat hippocampus membranes by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 57nMAssay Description:Displacement of [125I]]-alpha-bungarotoxin from alpha7 nAChR in rat hippocampus membranes by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 104nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from human alpha7 nAChR expressed in human SH-SY5Y cell membranes after 30 mins by gamma counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 119nMAssay Description:Displacement of [125I]]-alpha-bungarotoxin from alpha7 nAChR in rat hippocampus membranes by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataKi: 160nMAssay Description:Displacement of [3H](-)cytisine from rat whole brain alpha4beta2 nAChRMore data for this Ligand-Target Pair
Affinity DataKi: 164nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from human alpha7 nAChR expressed in human SH-SY5Y cell membranes after 30 mins by gamma counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 186nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from human alpha7 nAChR expressed in human SH-SY5Y cell membranes after 30 mins by gamma counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 189nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from human alpha7 nAChR expressed in human SH-SY5Y cell membranes after 30 mins by gamma counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 212nMAssay Description:Displacement of [125I]]-alpha-bungarotoxin from alpha7 nAChR in rat hippocampus membranes by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 234nMAssay Description:Displacement of [125I]]-alpha-bungarotoxin from alpha7 nAChR in rat hippocampus membranes by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataKi: 257nMAssay Description:Displacement of [3H]epibatidine from human alpha3beta4 nAChR expressed in HEK293 cells pretreated for 5 mins followed by [3H]epibatidine addition aft...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataKi: 261nMAssay Description:Displacement of [3H]epibatidine from human alpha3beta4 nAChR expressed in HEK293 cells pretreated for 5 mins followed by [3H]epibatidine addition aft...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataKi: 271nMAssay Description:Displacement of [3H]epibatidine from human alpha3beta4 nAChR expressed in HEK293 cells pretreated for 5 mins followed by [3H]epibatidine addition aft...More data for this Ligand-Target Pair
Affinity DataKi: 305nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from human alpha7 nAChR expressed in human SH-SY5Y cell membranes after 30 mins by gamma counting analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataKi: 310nMAssay Description:Displacement of [3H]epibatidine from human alpha3beta4 nAChR expressed in HEK293 cells pretreated for 5 mins followed by [3H]epibatidine addition aft...More data for this Ligand-Target Pair
Affinity DataKi: 321nMAssay Description:Displacement of [125I]]-alpha-bungarotoxin from alpha7 nAChR in rat hippocampus membranes by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 388nMAssay Description:Displacement of [125I]]-alpha-bungarotoxin from alpha7 nAChR in rat hippocampus membranes by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 465nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from human alpha7 nAChR expressed in human SH-SY5Y cell membranes after 30 mins by gamma counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 559nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from human alpha7 nAChR expressed in human SH-SY5Y cell membranes after 30 mins by gamma counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 617nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from human alpha7 nAChR expressed in human SH-SY5Y cell membranes after 30 mins by gamma counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 743nMAssay Description:Displacement of [125I]]-alpha-bungarotoxin from alpha7 nAChR in rat hippocampus membranes by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 909nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from human alpha7 nAChR expressed in human SH-SY5Y cell membranes after 30 mins by gamma counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 984nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from human alpha7 nAChR expressed in human SH-SY5Y cell membranes after 30 mins by gamma counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.15E+3nMAssay Description:Displacement of [125I]]-alpha-bungarotoxin from alpha7 nAChR in rat hippocampus membranes by liquid scintillation counting methodMore data for this Ligand-Target Pair
