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Target5-hydroxytryptamine receptor 2C(Human)
Shionogi & Co.

US Patent
LigandPNGBDBM657790(US20240083872, Compound I-086)
Affinity DataKi:  0.241nMAssay Description:Binding Test of the Compound According to the Present Invention:In advance, 0.5 μL of the compound solution dissolved in DMSO was dispensed into...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Shionogi & Co.

US Patent
LigandPNGBDBM657800(US20240083872, Compound I-122)
Affinity DataKi:  0.281nMAssay Description:Binding Test of the Compound According to the Present Invention:In advance, 0.5 μL of the compound solution dissolved in DMSO was dispensed into...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Shionogi & Co.

US Patent
LigandPNGBDBM657797(US20240083872, Compound I-110)
Affinity DataKi:  0.301nMAssay Description:Binding Test of the Compound According to the Present Invention:In advance, 0.5 μL of the compound solution dissolved in DMSO was dispensed into...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Shionogi & Co.

US Patent
LigandPNGBDBM657798(US20240083872, Compound I-117)
Affinity DataKi:  0.315nMAssay Description:Binding Test of the Compound According to the Present Invention:In advance, 0.5 μL of the compound solution dissolved in DMSO was dispensed into...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Shionogi & Co.

US Patent
LigandPNGBDBM657795(US20240083872, Compound I-107)
Affinity DataKi:  0.340nMAssay Description:Binding Test of the Compound According to the Present Invention:In advance, 0.5 μL of the compound solution dissolved in DMSO was dispensed into...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Shionogi & Co.

US Patent
LigandPNGBDBM657799(US20240083872, Compound I-118)
Affinity DataKi:  0.371nMAssay Description:Binding Test of the Compound According to the Present Invention:In advance, 0.5 μL of the compound solution dissolved in DMSO was dispensed into...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Shionogi & Co.

US Patent
LigandPNGBDBM657792(US20240083872, Compound I-102)
Affinity DataKi:  0.412nMAssay Description:Binding Test of the Compound According to the Present Invention:In advance, 0.5 μL of the compound solution dissolved in DMSO was dispensed into...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shionogi & Co.

US Patent
LigandPNGBDBM657796(US20240083872, Compound I-109)
Affinity DataKi:  0.430nMAssay Description:Binding Test of the Compound According to the Present Invention: In advance, 0.5 μL of the compound solution dissolved in DMSO was dispensed int...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Shionogi & Co.

US Patent
LigandPNGBDBM657791(US20240083872, Compound I-101)
Affinity DataKi:  0.461nMAssay Description:Binding Test of the Compound According to the Present Invention:In advance, 0.5 μL of the compound solution dissolved in DMSO was dispensed into...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Shionogi & Co.

US Patent
LigandPNGBDBM657796(US20240083872, Compound I-109)
Affinity DataKi:  0.463nMAssay Description:Binding Test of the Compound According to the Present Invention:In advance, 0.5 μL of the compound solution dissolved in DMSO was dispensed into...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Shionogi & Co.

US Patent
LigandPNGBDBM657794(US20240083872, Compound I-104)
Affinity DataKi:  0.484nMAssay Description:Binding Test of the Compound According to the Present Invention:In advance, 0.5 μL of the compound solution dissolved in DMSO was dispensed into...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shionogi & Co.

US Patent
LigandPNGBDBM657790(US20240083872, Compound I-086)
Affinity DataKi:  0.503nMAssay Description:Binding Test of the Compound According to the Present Invention: In advance, 0.5 μL of the compound solution dissolved in DMSO was dispensed int...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shionogi & Co.

US Patent
LigandPNGBDBM657801(US20240083872, Compound I-123)
Affinity DataKi:  0.506nMAssay Description:Binding Test of the Compound According to the Present Invention: In advance, 0.5 μL of the compound solution dissolved in DMSO was dispensed int...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shionogi & Co.

US Patent
LigandPNGBDBM657797(US20240083872, Compound I-110)
Affinity DataKi:  0.537nMAssay Description:Binding Test of the Compound According to the Present Invention: In advance, 0.5 μL of the compound solution dissolved in DMSO was dispensed int...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shionogi & Co.

US Patent
LigandPNGBDBM657795(US20240083872, Compound I-107)
Affinity DataKi:  0.549nMAssay Description:Binding Test of the Compound According to the Present Invention: In advance, 0.5 μL of the compound solution dissolved in DMSO was dispensed int...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Shionogi & Co.

US Patent
LigandPNGBDBM657793(US20240083872, Compound I-103)
Affinity DataKi:  0.634nMAssay Description:Binding Test of the Compound According to the Present Invention:In advance, 0.5 μL of the compound solution dissolved in DMSO was dispensed into...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shionogi & Co.

US Patent
LigandPNGBDBM657792(US20240083872, Compound I-102)
Affinity DataKi:  0.642nMAssay Description:Binding Test of the Compound According to the Present Invention: In advance, 0.5 μL of the compound solution dissolved in DMSO was dispensed int...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shionogi & Co.

US Patent
LigandPNGBDBM657791(US20240083872, Compound I-101)
Affinity DataKi:  0.683nMAssay Description:Binding Test of the Compound According to the Present Invention: In advance, 0.5 μL of the compound solution dissolved in DMSO was dispensed int...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shionogi & Co.

US Patent
LigandPNGBDBM657784(US20240083872, Compound I-031)
Affinity DataKi:  0.709nMAssay Description:Binding Test of the Compound According to the Present Invention: In advance, 0.5 μL of the compound solution dissolved in DMSO was dispensed int...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shionogi & Co.

US Patent
LigandPNGBDBM657798(US20240083872, Compound I-117)
Affinity DataKi:  0.820nMAssay Description:Binding Test of the Compound According to the Present Invention: In advance, 0.5 μL of the compound solution dissolved in DMSO was dispensed int...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shionogi & Co.

US Patent
LigandPNGBDBM657800(US20240083872, Compound I-122)
Affinity DataKi:  0.824nMAssay Description:Binding Test of the Compound According to the Present Invention: In advance, 0.5 μL of the compound solution dissolved in DMSO was dispensed int...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shionogi & Co.

US Patent
LigandPNGBDBM657794(US20240083872, Compound I-104)
Affinity DataKi:  0.952nMAssay Description:Binding Test of the Compound According to the Present Invention: In advance, 0.5 μL of the compound solution dissolved in DMSO was dispensed int...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shionogi & Co.

US Patent
LigandPNGBDBM657779(US20240083872, Compound I-006)
Affinity DataKi:  0.968nMAssay Description:Binding Test of the Compound According to the Present Invention: In advance, 0.5 μL of the compound solution dissolved in DMSO was dispensed int...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shionogi & Co.

US Patent
LigandPNGBDBM657799(US20240083872, Compound I-118)
Affinity DataKi:  1.03nMAssay Description:Binding Test of the Compound According to the Present Invention: In advance, 0.5 μL of the compound solution dissolved in DMSO was dispensed int...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shionogi & Co.

US Patent
LigandPNGBDBM657802(US20240083872, Compound I-126)
Affinity DataKi:  1.24nMAssay Description:Binding Test of the Compound According to the Present Invention: In advance, 0.5 μL of the compound solution dissolved in DMSO was dispensed int...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Shionogi & Co.

US Patent
LigandPNGBDBM657801(US20240083872, Compound I-123)
Affinity DataKi:  1.39nMAssay Description:Binding Test of the Compound According to the Present Invention:In advance, 0.5 μL of the compound solution dissolved in DMSO was dispensed into...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Shionogi & Co.

US Patent
LigandPNGBDBM657784(US20240083872, Compound I-031)
Affinity DataKi:  1.89nMAssay Description:Binding Test of the Compound According to the Present Invention:In advance, 0.5 μL of the compound solution dissolved in DMSO was dispensed into...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shionogi & Co.

US Patent
LigandPNGBDBM657793(US20240083872, Compound I-103)
Affinity DataKi:  1.89nMAssay Description:Binding Test of the Compound According to the Present Invention: In advance, 0.5 μL of the compound solution dissolved in DMSO was dispensed int...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent

TargetBeta-secretase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50501808(CHEMBL4465534)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]-JNJ-962 from BACE1 (unknown origin) expressed in HEK293 cell membranes by scintillation counting methodMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Human)
Shionogi & Co.

US Patent
LigandPNGBDBM657786(US20240083872, Compound I-037)
Affinity DataKi:  2.11nMAssay Description:Binding Test of the Compound According to the Present Invention:In advance, 0.5 μL of the compound solution dissolved in DMSO was dispensed into...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shionogi & Co.

US Patent
LigandPNGBDBM657787(US20240083872, Compound I-043)
Affinity DataKi:  2.14nMAssay Description:Binding Test of the Compound According to the Present Invention: In advance, 0.5 μL of the compound solution dissolved in DMSO was dispensed int...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shionogi & Co.

US Patent
LigandPNGBDBM657783(US20240083872, Compound I-030)
Affinity DataKi:  2.17nMAssay Description:Binding Test of the Compound According to the Present Invention: In advance, 0.5 μL of the compound solution dissolved in DMSO was dispensed int...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Shionogi & Co.

US Patent
LigandPNGBDBM657779(US20240083872, Compound I-006)
Affinity DataKi:  2.47nMAssay Description:Binding Test of the Compound According to the Present Invention:In advance, 0.5 μL of the compound solution dissolved in DMSO was dispensed into...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shionogi & Co.

US Patent
LigandPNGBDBM657789(US20240083872, Compound I-084)
Affinity DataKi:  2.61nMAssay Description:Binding Test of the Compound According to the Present Invention: In advance, 0.5 μL of the compound solution dissolved in DMSO was dispensed int...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Shionogi & Co.

US Patent
LigandPNGBDBM657787(US20240083872, Compound I-043)
Affinity DataKi:  3.07nMAssay Description:Binding Test of the Compound According to the Present Invention:In advance, 0.5 μL of the compound solution dissolved in DMSO was dispensed into...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shionogi & Co.

US Patent
LigandPNGBDBM657788(US20240083872, Compound I-046)
Affinity DataKi:  3.09nMAssay Description:Binding Test of the Compound According to the Present Invention: In advance, 0.5 μL of the compound solution dissolved in DMSO was dispensed int...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent

TargetBeta-secretase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50501810(CHEMBL4443968)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]-JNJ-962 from BACE1 (unknown origin) expressed in HEK293 cell membranes by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Human)
Shionogi & Co.

US Patent
LigandPNGBDBM657785(US20240083872, Compound I-033)
Affinity DataKi:  4.01nMAssay Description:Binding Test of the Compound According to the Present Invention: In advance, 0.5 μL of the compound solution dissolved in DMSO was dispensed int...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shionogi & Co.

US Patent
LigandPNGBDBM657782(US20240083872, Compound I-029)
Affinity DataKi:  4.33nMAssay Description:Binding Test of the Compound According to the Present Invention: In advance, 0.5 μL of the compound solution dissolved in DMSO was dispensed int...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shionogi & Co.

US Patent
LigandPNGBDBM657778(US20240083872, Compound I-004)
Affinity DataKi:  4.51nMAssay Description:Binding Test of the Compound According to the Present Invention: In advance, 0.5 μL of the compound solution dissolved in DMSO was dispensed int...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shionogi & Co.

US Patent
LigandPNGBDBM657786(US20240083872, Compound I-037)
Affinity DataKi:  4.70nMAssay Description:Binding Test of the Compound According to the Present Invention: In advance, 0.5 μL of the compound solution dissolved in DMSO was dispensed int...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Shionogi & Co.

US Patent
LigandPNGBDBM657789(US20240083872, Compound I-084)
Affinity DataKi:  5.78nMAssay Description:Binding Test of the Compound According to the Present Invention:In advance, 0.5 μL of the compound solution dissolved in DMSO was dispensed into...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shionogi & Co.

US Patent
LigandPNGBDBM657780(US20240083872, Compound I-012)
Affinity DataKi:  6.02nMAssay Description:Binding Test of the Compound According to the Present Invention: In advance, 0.5 μL of the compound solution dissolved in DMSO was dispensed int...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Shionogi & Co.

US Patent
LigandPNGBDBM657802(US20240083872, Compound I-126)
Affinity DataKi:  6.25nMAssay Description:Binding Test of the Compound According to the Present Invention:In advance, 0.5 μL of the compound solution dissolved in DMSO was dispensed into...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent

TargetBeta-secretase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50501818(CHEMBL4583340)
Affinity DataKi:  6.5nMAssay Description:Displacement of [3H]-JNJ-962 from BACE1 (unknown origin) expressed in HEK293 cell membranes by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Human)
Shionogi & Co.

US Patent
LigandPNGBDBM657783(US20240083872, Compound I-030)
Affinity DataKi:  7.76nMAssay Description:Binding Test of the Compound According to the Present Invention:In advance, 0.5 μL of the compound solution dissolved in DMSO was dispensed into...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Shionogi & Co.

US Patent
LigandPNGBDBM657527(US20240083872, Compound I-003)
Affinity DataKi:  8.39nMAssay Description:Binding Test of the Compound According to the Present Invention:In advance, 0.5 μL of the compound solution dissolved in DMSO was dispensed into...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shionogi & Co.

US Patent
LigandPNGBDBM657527(US20240083872, Compound I-003)
Affinity DataKi:  9.93nMAssay Description:Binding Test of the Compound According to the Present Invention: In advance, 0.5 μL of the compound solution dissolved in DMSO was dispensed int...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Shionogi & Co.

US Patent
LigandPNGBDBM657803(US20240083872, Compound I-001 | US20240083872, Com...)
Affinity DataKi: <10nMAssay Description:Binding Test of the Compound According to the Present Invention:In advance, 0.5 μL of the compound solution dissolved in DMSO was dispensed into...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Shionogi & Co.

US Patent
LigandPNGBDBM657813(US20240083872, Compound I-016)
Affinity DataKi: <10nMAssay Description:Binding Test of the Compound According to the Present Invention:In advance, 0.5 μL of the compound solution dissolved in DMSO was dispensed into...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent

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