Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 1316 with Last Name = 'nakamura' and Initial = 's'
TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM35723(CHEMBL344159 | N-[4-(7-Chloro-5-hydroxy-2,3,4,5-te...)
Affinity DataKi:  0.430nMAssay Description:Concentration of the compound which inhibit [3H]-AVP binding to human Vasopressin V2 receptor coded HeLa cells by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM35723(CHEMBL344159 | N-[4-(7-Chloro-5-hydroxy-2,3,4,5-te...)
Affinity DataKi:  0.430nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVasopressin V1b receptor(Human)
Second Tokushima Institute of New Drug Research

Curated by PDSP Ki Database
LigandPNGBDBM35667(AVP | CHEMBL373742 | US10131692, 44 (AVP) | [3H]Ar...)
Affinity DataKi:  0.590nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM35667(AVP | CHEMBL373742 | US10131692, 44 (AVP) | [3H]Ar...)
Affinity DataKi:  0.780nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVasopressin V2 receptor(Rat)
Second Tokushima Institute of New Drug Research

Curated by PDSP Ki Database
LigandPNGBDBM35667(AVP | CHEMBL373742 | US10131692, 44 (AVP) | [3H]Ar...)
Affinity DataKi:  0.950nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVasopressin V2 receptor(Rat)
Second Tokushima Institute of New Drug Research

Curated by PDSP Ki Database
LigandPNGBDBM35723(CHEMBL344159 | N-[4-(7-Chloro-5-hydroxy-2,3,4,5-te...)
Affinity DataKi:  1.33nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVasopressin V1a receptor(Rat)
Second Tokushima Institute of New Drug Research

Curated by PDSP Ki Database
LigandPNGBDBM35667(AVP | CHEMBL373742 | US10131692, 44 (AVP) | [3H]Ar...)
Affinity DataKi:  1.45nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVasopressin V2 receptor(Rat)
Second Tokushima Institute of New Drug Research

Curated by PDSP Ki Database
LigandPNGBDBM35714(CHEMBL420762 | Mozavaptan | N-[4-(5-Dimethylamino-...)
Affinity DataKi:  6.36nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM35714(CHEMBL420762 | Mozavaptan | N-[4-(5-Dimethylamino-...)
Affinity DataKi:  9.42nMAssay Description:Concentration of the compound which inhibit [3H]-AVP binding to human Vasopressin V2 receptor coded HeLa cells by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM35714(CHEMBL420762 | Mozavaptan | N-[4-(5-Dimethylamino-...)
Affinity DataKi:  9.42nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVasopressin V1a receptor(Human)
Second Tokushima Institute of New Drug Research

Curated by PDSP Ki Database
LigandPNGBDBM35723(CHEMBL344159 | N-[4-(7-Chloro-5-hydroxy-2,3,4,5-te...)
Affinity DataKi:  12.3nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVasopressin V1a receptor(Rat)
Second Tokushima Institute of New Drug Research

Curated by PDSP Ki Database
LigandPNGBDBM50029644(CHEMBL296908 | N-(3-(4-(4-(2-oxo-3,4-dihydroquinol...)
Affinity DataKi:  32nMAssay Description:Binding affinity of the compound towards Vasopressin V1a receptor in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50175277(CHEMBL3809675)
Affinity DataKi:  40nMAssay Description:Inhibition of recombinant human SphK1 expressed in baculovirus infected sf9 cells using D-erythro-sphingosine as substrate in presence of [gamma-33P]...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Human)
Second Tokushima Institute of New Drug Research

Curated by PDSP Ki Database
LigandPNGBDBM35714(CHEMBL420762 | Mozavaptan | N-[4-(5-Dimethylamino-...)
Affinity DataKi:  150nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMaltase-glucoamylase(Human)
Kindai University

Curated by ChEMBL
LigandPNGBDBM50330955((1S,2S)-3-[(2R,3S,4S)-3,4-dihydroxy-2-(hydroxymeth...)
Affinity DataKi:  190nMAssay Description:Inhibition of recombinant human maltase-glucoamylase using p-nitrophenyl-alpha-D-glucopyranoside as substrate incubated for 35 mins by microtiter pla...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Rat)
Second Tokushima Institute of New Drug Research

Curated by PDSP Ki Database
LigandPNGBDBM35723(CHEMBL344159 | N-[4-(7-Chloro-5-hydroxy-2,3,4,5-te...)
Affinity DataKi:  325nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVasopressin V1a receptor(Rat)
Second Tokushima Institute of New Drug Research

Curated by PDSP Ki Database
LigandPNGBDBM35714(CHEMBL420762 | Mozavaptan | N-[4-(5-Dimethylamino-...)
Affinity DataKi:  524nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSphingosine kinase 2(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM174110((S)-2-(3-(4-octylphenyl)-1,2,4- oxadiazol-5-yl)aze...)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of recombinant human SphK2 expressed in baculovirus infected sf9 cells using D-erythro-sphingosine as substrate after 20 mins in presence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMaltase-glucoamylase(Human)
Kindai University

Curated by ChEMBL
LigandPNGBDBM50549692(CHEMBL4749306)
Affinity DataKi:  6.00E+3nMAssay Description:Inhibition of recombinant human maltase-glucoamylase using p-nitrophenyl-alpha-D-glucopyranoside as substrate incubated for 35 mins by microtiter pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVasopressin V1b receptor(Human)
Second Tokushima Institute of New Drug Research

Curated by PDSP Ki Database
LigandPNGBDBM35723(CHEMBL344159 | N-[4-(7-Chloro-5-hydroxy-2,3,4,5-te...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSphingosine kinase 1(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM174110((S)-2-(3-(4-octylphenyl)-1,2,4- oxadiazol-5-yl)aze...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of recombinant human SphK1 expressed in baculovirus infected sf9 cells using D-erythro-sphingosine as substrate after 20 mins in presence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1b receptor(Human)
Second Tokushima Institute of New Drug Research

Curated by PDSP Ki Database
LigandPNGBDBM35714(CHEMBL420762 | Mozavaptan | N-[4-(5-Dimethylamino-...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVasopressin V1a receptor(Human)
Second Tokushima Institute of New Drug Research

Curated by PDSP Ki Database
LigandPNGBDBM50029644(CHEMBL296908 | N-(3-(4-(4-(2-oxo-3,4-dihydroquinol...)
Affinity DataKi:  1.40E+4nMAssay Description:Binding affinity of the compound towards Vasopressin V1a receptor in human liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 2(Mouse)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50175277(CHEMBL3809675)
Affinity DataKi:  1.41E+4nMAssay Description:Inhibition of recombinant mouse SphK2 expressed in baculovirus infected sf9 cells using D-erythro-sphingosine as substrate in presence of [gamma-33P]...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMaltase-glucoamylase(Human)
Kindai University

Curated by ChEMBL
LigandPNGBDBM50549691(CHEMBL4754034)
Affinity DataKi:  3.20E+4nMAssay Description:Inhibition of recombinant human maltase-glucoamylase using p-nitrophenyl-alpha-D-glucopyranoside as substrate incubated for 35 mins by microtiter pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMaltase-glucoamylase(Human)
Kindai University

Curated by ChEMBL
LigandPNGBDBM50549693(CHEMBL4750690)
Affinity DataKi:  5.10E+4nMAssay Description:Inhibition of recombinant human maltase-glucoamylase using p-nitrophenyl-alpha-D-glucopyranoside as substrate incubated for 35 mins by microtiter pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50258896(CHEMBL4060569 | US11419874, TAK-915)
Affinity DataIC50:  0.610nMAssay Description:Inhibition of recombinant human full-length His-tagged PDE2A3 expressed in fall armyworm Sf9 cells using [3H]cGMP as substrate preincubated for 30 mi...More data for this Ligand-Target Pair
TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50094076(CHEMBL434654 | N-[4-(7-Chloro-2,3,4,5-tetrahydro-b...)
Affinity DataIC50:  0.950nMAssay Description:Concentration of the compound which inhibit [3H]-AVP binding to human Vasopressin V2 receptor coded HeLa cells by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM107767(US11419874, PF-05180999 | US8598155, 2)
Affinity DataIC50:  1nMAssay Description:Inhibition of recombinant human FLAG-tagged PDE2A3 expressed in sf21 cells using [3H]cGMP as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50258930(CHEMBL4102321)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of recombinant human full-length His-tagged PDE2A3 expressed in fall armyworm Sf9 cells using [3H]cGMP as substrate preincubated for 30 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50041978(CHEMBL3134157)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of recombinant C-terminal His6-tagged human SphK1 expressed in baculovirus infected sf21 cells using FITC-sphingosine as substrate after 1...More data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50258926(CHEMBL4064402)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of recombinant human full-length His-tagged PDE2A3 expressed in fall armyworm Sf9 cells using [3H]cGMP as substrate preincubated for 30 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM35718(benzazepine derivative, 20)
Affinity DataIC50:  3nMpH: 7.4 T: 4°CAssay Description:After reaching confluence in 12-well or 24-well dishes, the cells were washed twice with ice-cold PBS and incubated for 2 hr with [3H]-AVP at 4 deg C...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM35723(CHEMBL344159 | N-[4-(7-Chloro-5-hydroxy-2,3,4,5-te...)
Affinity DataIC50:  3nMpH: 7.4 T: 4°CAssay Description:After reaching confluence in 12-well or 24-well dishes, the cells were washed twice with ice-cold PBS and incubated for 2 hr with [3H]-AVP at 4 deg C...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50258929(CHEMBL4072982)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of recombinant human full-length His-tagged PDE2A3 expressed in fall armyworm Sf9 cells using [3H]cGMP as substrate preincubated for 30 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50094079((4-Amino-2-methyl-phenyl)-(7-chloro-2,3,4,5-tetrah...)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of [3H]-AVP binding to human Vasopressin V2 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase II subunit alpha'(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50144654(CHEMBL3760043)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of GST-tagged human CK2alpha' (1 to 350 residues) using CK2tide as substrate incubated for 1 hr by off-chip mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50166893(2-(3,4-Dimethoxy-benzyl)-7-[(R)-1-((R)-1-hydroxy-e...)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of PDE2A (unknown origin) using [3H]cGMP as substrate after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM35725(benzazepine derivative, 34)
Affinity DataIC50:  5nMpH: 7.4 T: 4°CAssay Description:After reaching confluence in 12-well or 24-well dishes, the cells were washed twice with ice-cold PBS and incubated for 2 hr with [3H]-AVP at 4 deg C...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM35719(benzazepine derivative, 21)
Affinity DataIC50:  5nMpH: 7.4 T: 4°CAssay Description:After reaching confluence in 12-well or 24-well dishes, the cells were washed twice with ice-cold PBS and incubated for 2 hr with [3H]-AVP at 4 deg C...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50094068((2-Chloro-4-ethylamino-phenyl)-(7-chloro-2,3,4,5-t...)
Affinity DataIC50:  5nMAssay Description:Inhibition of [3H]-AVP binding to human Vasopressin V2 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50094086((4-Allylamino-2-chloro-phenyl)-(2,3,4,5-tetrahydro...)
Affinity DataIC50:  5.90nMAssay Description:Inhibition of [3H]-AVP binding to human Vasopressin V2 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Human)
Second Tokushima Institute of New Drug Research

Curated by PDSP Ki Database
LigandPNGBDBM35725(benzazepine derivative, 34)
Affinity DataIC50:  7nMAssay Description:After reaching confluence in 12-well or 24-well dishes, the cells were washed twice with ice-cold PBS and incubated for 2 hr with [3H]-AVP at 4 deg C...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM35715(benzazepine derivative, 13a)
Affinity DataIC50:  7nMpH: 7.4 T: 4°CAssay Description:After reaching confluence in 12-well or 24-well dishes, the cells were washed twice with ice-cold PBS and incubated for 2 hr with [3H]-AVP at 4 deg C...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50258894(CHEMBL4067117)
Affinity DataIC50:  7.20nMAssay Description:Inhibition of recombinant human full-length His-tagged PDE2A3 expressed in fall armyworm Sf9 cells using [3H]cGMP as substrate preincubated for 30 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50258894(CHEMBL4067117)
Affinity DataIC50:  7.20nMAssay Description:Inhibition of human N-terminal GST/C-terminal His-tagged PDE7B (109 to end residues) expressed in baculovirus infected fall armyworm Sf9 cells using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50094082((2-Chloro-4-pyrrol-1-yl-phenyl)-(2,3,4,5-tetrahydr...)
Affinity DataIC50:  7.5nMAssay Description:Inhibition of [3H]-AVP binding to human Vasopressin V2 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM35721(benzazepine derivative, 30)
Affinity DataIC50:  8nMpH: 7.4 T: 4°CAssay Description:After reaching confluence in 12-well or 24-well dishes, the cells were washed twice with ice-cold PBS and incubated for 2 hr with [3H]-AVP at 4 deg C...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50258923(CHEMBL4085207)
Affinity DataIC50:  8.70nMAssay Description:Inhibition of recombinant human full-length His-tagged PDE2A3 expressed in fall armyworm Sf9 cells using [3H]cGMP as substrate preincubated for 30 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase II subunit alpha'(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50144679(CHEMBL3759871)
Affinity DataIC50:  8.80nMAssay Description:Inhibition of GST-tagged human CK2alpha' (1 to 350 residues) using CK2tide as substrate incubated for 1 hr by off-chip mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 1316 total ) | Next | Last >>
Jump to: