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TargetKappa-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50494229(CHEMBL3215960)
Affinity DataEC50:  293nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50494230(CHEMBL3217051)
Affinity DataEC50:  33nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50494228(CHEMBL3217271)
Affinity DataEC50:  40nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50494234(CHEMBL3216611)
Affinity DataEC50:  20nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50494234(CHEMBL3216611)
Affinity DataEC50:  7.5nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50494236(CHEMBL3086465)
Affinity DataEC50:  21nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50494228(CHEMBL3217271)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50494235(CHEMBL3216613)
Affinity DataEC50:  38nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50494228(CHEMBL3217271)
Affinity DataEC50:  2.70nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50494237(CHEMBL3217050)
Affinity DataEC50:  60nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50494233(CHEMBL3217273)
Affinity DataEC50:  130nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50494231(CHEMBL3217272)
Affinity DataEC50:  15nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50494235(CHEMBL3216613)
Affinity DataEC50:  6.5nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50494231(CHEMBL3217272)
Affinity DataEC50:  15nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50494229(CHEMBL3215960)
Affinity DataEC50:  18nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM21008((4S,7S,13S)-13-[(2S)-2-amino-3-(4-hydroxyphenyl)pr...)
Affinity DataEC50:  13nMAssay Description:Agonist activity at human delta opioid receptor over-expressed in CHO cell membrane after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50499193(CHEMBL3735897)
Affinity DataEC50:  6.60E+3nMAssay Description:Agonist activity at human delta opioid receptor over-expressed in CHO cell membrane after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50262994(N-Methyl-2-(3-bromophenyl)ethylamine | CHEMBL47675...)
Affinity DataEC50:  1.07E+3nMAssay Description:Agonist activity at human trace amine associated receptor 1 expressed in RD-HGA16 CHO-K1 cells coexpressed with Galpha16 protein assessed as internal...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50262949(N,N-Dimethyl-2-(2-bromophenyl)ethylamine | CHEMBL5...)
Affinity DataEC50:  3.46E+3nMAssay Description:Agonist activity at human trace amine associated receptor 1 expressed in RD-HGA16 CHO-K1 cells coexpressed with Galpha16 protein assessed as internal...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50262948(N-Methyl-2-(2-bromophenyl)ethylamine | CHEMBL47884...)
Affinity DataEC50:  205nMAssay Description:Agonist activity at human trace amine associated receptor 1 expressed in RD-HGA16 CHO-K1 cells coexpressed with Galpha16 protein assessed as internal...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50262947(N,N-Dimethyl-2-(4-chlorophenyl)ethylamine | CHEMBL...)
Affinity DataEC50:  6.30E+5nMAssay Description:Agonist activity at human trace amine associated receptor 1 expressed in RD-HGA16 CHO-K1 cells coexpressed with Galpha16 protein assessed as internal...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50262946(N-Methyl-2-(4-chlorophenyl)ethylamine | CHEMBL4529...)
Affinity DataEC50:  7.43E+3nMAssay Description:Agonist activity at human trace amine associated receptor 1 expressed in RD-HGA16 CHO-K1 cells coexpressed with Galpha16 protein assessed as internal...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50053591([2-(3-Chloro-phenyl)-ethyl]-dimethyl-amine | N,N-D...)
Affinity DataEC50:  5.98E+3nMAssay Description:Agonist activity at human trace amine associated receptor 1 expressed in RD-HGA16 CHO-K1 cells coexpressed with Galpha16 protein assessed as internal...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50053602([2-(3-Chloro-phenyl)-ethyl]-methyl-amine | N-Methy...)
Affinity DataEC50:  501nMAssay Description:Agonist activity at human trace amine associated receptor 1 expressed in RD-HGA16 CHO-K1 cells coexpressed with Galpha16 protein assessed as internal...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50262945(N,N-Dimethyl-2-(2-chlorophenyl)ethylamine | CHEMBL...)
Affinity DataEC50:  687nMAssay Description:Agonist activity at human trace amine associated receptor 1 expressed in RD-HGA16 CHO-K1 cells coexpressed with Galpha16 protein assessed as internal...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50262944(N,N-Dimethyl-2-(4-fluorophenyl)ethylamine | CHEMBL...)
Affinity DataEC50:  160nMAssay Description:Agonist activity at human trace amine associated receptor 1 expressed in RD-HGA16 CHO-K1 cells coexpressed with Galpha16 protein assessed as internal...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50262943(2-(4-fluorophenyl)-N,N-dimethylethanamine | CHEMBL...)
Affinity DataEC50:  1.91E+4nMAssay Description:Agonist activity at human trace amine associated receptor 1 expressed in RD-HGA16 CHO-K1 cells coexpressed with Galpha16 protein assessed as internal...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50262942(N-Methyl-2-(4-fluorophenyl)ethylamine | CHEMBL4763...)
Affinity DataEC50:  1.04E+3nMAssay Description:Agonist activity at human trace amine associated receptor 1 expressed in RD-HGA16 CHO-K1 cells coexpressed with Galpha16 protein assessed as internal...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50262941(N,N-Dimethyl-2-(3-fluorophenyl)ethylamine | CHEMBL...)
Affinity DataEC50:  4.32E+3nMAssay Description:Agonist activity at human trace amine associated receptor 1 expressed in RD-HGA16 CHO-K1 cells coexpressed with Galpha16 protein assessed as internal...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50262940(N-Methyl-2-(3-fluorophenyl)ethylamine | CHEMBL4461...)
Affinity DataEC50:  530nMAssay Description:Agonist activity at human trace amine associated receptor 1 expressed in RD-HGA16 CHO-K1 cells coexpressed with Galpha16 protein assessed as internal...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50262891(N,N-dimethyl-2-(2-fluorophenyl)ethylamine | CHEMBL...)
Affinity DataEC50:  1.29E+3nMAssay Description:Agonist activity at human trace amine associated receptor 1 expressed in RD-HGA16 CHO-K1 cells coexpressed with Galpha16 protein assessed as internal...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50262890(N-Methyl-2-(2-fluorophenyl)ethylamine | CHEMBL4431...)
Affinity DataEC50:  117nMAssay Description:Agonist activity at human trace amine associated receptor 1 expressed in RD-HGA16 CHO-K1 cells coexpressed with Galpha16 protein assessed as internal...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50018453(Dimethyl-phenethyl-amine | CHEMBL46278 | N,N-dimet...)
Affinity DataEC50:  1.00E+5nMAssay Description:Agonist activity at human trace amine associated receptor 1 expressed in RD-HGA16 CHO-K1 cells coexpressed with Galpha16 protein assessed as internal...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50240500(N-methyl-2-phenylelthylamine | Methyl-phenethyl-am...)
Affinity DataEC50:  387nMAssay Description:Agonist activity at human trace amine associated receptor 1 expressed in RD-HGA16 CHO-K1 cells coexpressed with Galpha16 protein assessed as internal...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50246598(2-methyl-1-phenylpropan-2-amine | CHEMBL1574 | alp...)
Affinity DataEC50:  5.47E+3nMAssay Description:Agonist activity at human trace amine associated receptor 1 expressed in RD-HGA16 CHO-K1 cells coexpressed with Galpha16 protein assessed as internal...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50022721((R)-amphetamine | CHEMBL19393 | AMPHETAMINE)
Affinity DataEC50:  920nMAssay Description:Agonist activity at human trace amine associated receptor 1 expressed in RD-HGA16 CHO-K1 cells coexpressed with Galpha16 protein assessed as internal...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50022723((2S)-1-phenylpropan-2-amine | (S)-amphetamine | (+...)
Affinity DataEC50:  935nMAssay Description:Agonist activity at human trace amine associated receptor 1 expressed in RD-HGA16 CHO-K1 cells coexpressed with Galpha16 protein assessed as internal...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetTrace amine-associated receptor 1(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50236898((1S,2R)-(+)-2-phenylcyclopropylamine | trans-2-phe...)
Affinity DataEC50:  1.51E+3nMAssay Description:Agonist activity at human trace amine associated receptor 1 expressed in RD-HGA16 CHO-K1 cells coexpressed with Galpha16 protein assessed as internal...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM35929(2,2-diphenylethylamine | CHEMBL10780 | 2,2-dipheny...)
Affinity DataEC50:  3.40E+3nMAssay Description:Agonist activity at human trace amine associated receptor 1 expressed in RD-HGA16 CHO-K1 cells coexpressed with Galpha16 protein assessed as internal...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50262889(3-Methyl-2-phenylbutylamine | CHEMBL476107)
Affinity DataEC50:  9.95E+3nMAssay Description:Agonist activity at human trace amine associated receptor 1 expressed in RD-HGA16 CHO-K1 cells coexpressed with Galpha16 protein assessed as internal...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50026628(C-(1-Phenyl-cyclopropyl)-methylamine | 1-Phenylcyc...)
Affinity DataEC50:  5.05E+3nMAssay Description:Agonist activity at human trace amine associated receptor 1 expressed in RD-HGA16 CHO-K1 cells coexpressed with Galpha16 protein assessed as internal...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50262888(2-Methyl-2-phenylpropylamine | CHEMBL505110)
Affinity DataEC50:  7.88E+3nMAssay Description:Agonist activity at human trace amine associated receptor 1 expressed in RD-HGA16 CHO-K1 cells coexpressed with Galpha16 protein assessed as internal...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50262841((R)-(+)-2-phenylpropylamine | CHEMBL508991)
Affinity DataEC50:  361nMAssay Description:Agonist activity at human trace amine associated receptor 1 expressed in RD-HGA16 CHO-K1 cells coexpressed with Galpha16 protein assessed as internal...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50262840((S)-(-)-2-phenylpropylamine | CHEMBL448232)
Affinity DataEC50:  129nMAssay Description:Agonist activity at human trace amine associated receptor 1 expressed in RD-HGA16 CHO-K1 cells coexpressed with Galpha16 protein assessed as internal...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50240696(2-(benzo[d][1,3]dioxol-5-yl)ethanamine | 2-Benzo[1...)
Affinity DataEC50:  5.03E+3nMAssay Description:Agonist activity at human trace amine associated receptor 1 expressed in RD-HGA16 CHO-K1 cells coexpressed with Galpha16 protein assessed as internal...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50240788(2-(2,5-dimethoxy-4-ethylphenyl)ethylamine | 2-(4-E...)
Affinity DataEC50:  6.41E+3nMAssay Description:Agonist activity at human trace amine associated receptor 1 expressed in RD-HGA16 CHO-K1 cells coexpressed with Galpha16 protein assessed as internal...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50240787(2-(2,5-dimethoxy-4-methylphenyl)ethylamine | 2-(2,...)
Affinity DataEC50:  6.48E+3nMAssay Description:Agonist activity at human trace amine associated receptor 1 expressed in RD-HGA16 CHO-K1 cells coexpressed with Galpha16 protein assessed as internal...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM29135(CHEMBL11608 | cid_5610 | tyramine | p-Tyramine)
Affinity DataEC50:  731nMAssay Description:Agonist activity at human trace amine associated receptor 1 expressed in RD-HGA16 CHO-K1 cells coexpressed with Galpha16 protein assessed as internal...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50020502(2-(3-hydroxyphenyl)ethylamine | 2-(3-Hydroxy-pheny...)
Affinity DataEC50:  1.74E+3nMAssay Description:Agonist activity at human trace amine associated receptor 1 expressed in RD-HGA16 CHO-K1 cells coexpressed with Galpha16 protein assessed as internal...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50240920(2-(2-Hydroxyphenyl)ethylamine | 2-(2-Amino-ethyl)-...)
Affinity DataEC50:  614nMAssay Description:Agonist activity at human trace amine associated receptor 1 expressed in RD-HGA16 CHO-K1 cells coexpressed with Galpha16 protein assessed as internal...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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