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TargetAcetylcholinesterase(Electric eel)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 50nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 50nMAssay Description:Inhibition of Electrophorus electricus C2888 AChE using acetylthiocholine iodide as substrate by Ellman's spectroscopic methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Electric eel)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50355396(CHEMBL1834808)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50355395(CHEMBL1834806)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50355395(CHEMBL1834806)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50355396(CHEMBL1834808)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50355397(CHEMBL1834807)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50355398(CHEMBL1834809)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50355397(CHEMBL1834807)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50355398(CHEMBL1834809)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50355399(CHEMBL1834877)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50355399(CHEMBL1834877)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50355400(CHEMBL1834810)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50355401(CHEMBL1834811)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50355400(CHEMBL1834810)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50355401(CHEMBL1834811)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50394654(CHEMBL188181)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of Electrophorus electricus C2888 AChE using acetylthiocholine iodide as substrate by Ellman's spectroscopic methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50394652(CHEMBL2165236)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of Electrophorus electricus C2888 AChE using acetylthiocholine iodide as substrate by Ellman's spectroscopic methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50394653(CHEMBL2165235)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of Electrophorus electricus C2888 AChE using acetylthiocholine iodide as substrate by Ellman's spectroscopic methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50394655(CHEMBL2165237)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of Electrophorus electricus C2888 AChE using acetylthiocholine iodide as substrate by Ellman's spectroscopic methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM26663((2S)-5,7-dihydroxy-8-(3-methylbut-2-en-1-yl)-2-phe...)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of Electrophorus electricus C2888 AChE using acetylthiocholine iodide as substrate by Ellman's spectroscopic methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50394656(CHEMBL2165240)
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibition of Electrophorus electricus C2888 AChE using acetylthiocholine iodide as substrate by Ellman's spectroscopic methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Institut De Chimie Des Substances Naturelles (Icsn)

Curated by ChEMBL
LigandPNGBDBM21447(4-(4-{[2-(4-chlorophenyl)phenyl]methyl}piperazin-1...)
Affinity DataKi: <1nMAssay Description:Displacement of fluorescein-labeled BAK from His-tagged BCL-XL (unknown origin) after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
LigandPNGBDBM50288953(CHEMBL1190672 | CHEMBL541347 | 11'N-(3-bromobenzyl...)
Affinity DataKi:  6.90nMAssay Description:Binding affinity towards sigma receptor in guinea pig brain membrane was determined by using [3H]DTG as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

LigandPNGBDBM50033369(SYMADINE | SYMMETREL | CHEMBL660 | AMANTADINE)
Affinity DataKi:  20nMAssay Description:Binding affinity towards sigma receptor in guinea pig brain membrane was determined by using [3H]DTG as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

LigandPNGBDBM50288954(CHEMBL1189234 | CHEMBL538300 | 11-benzyl-11-azahex...)
Affinity DataKi:  30nMAssay Description:Binding affinity towards sigma receptor in guinea pig brain membrane was determined by using [3H]DTG as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

LigandPNGBDBM50288949(CHEMBL552794 | CHEMBL1194508 | 11'N-(4-iodomobenzy...)
Affinity DataKi:  35nMAssay Description:Binding affinity towards sigma receptor in guinea pig brain membrane was determined by using [3H]DTG as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

LigandPNGBDBM50288950(CHEMBL539310 | CHEMBL1189714 | 11'N-(3-iodobenzyl)...)
Affinity DataKi:  58nMAssay Description:Binding affinity towards sigma receptor in guinea pig brain membrane was determined by using [3H]DTG as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

LigandPNGBDBM50288955(CHEMBL538057 | CHEMBL1189111 | 11'N-benzylspiro[di...)
Affinity DataKi:  79nMAssay Description:Binding affinity towards sigma receptor in guinea pig brain membrane was determined by using [3H]DTG as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

LigandPNGBDBM50288952(11-(3-bromobenzyl)-11-azahexacyclo[5.4.1.02,6.03,1...)
Affinity DataKi:  109nMAssay Description:Binding affinity towards sigma receptor in guinea pig brain membrane was determined by using [3H]DTG as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Institut De Chimie Des Substances Naturelles (Icsn)

Curated by ChEMBL
LigandPNGBDBM50022583(CHEMBL3298854)
Affinity DataKi:  5.20E+3nMAssay Description:Displacement of fluorescein-labeled BID from His-tagged MCL-1 (unknown origin) after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Institut De Chimie Des Substances Naturelles (Icsn)

Curated by ChEMBL
LigandPNGBDBM50295298(icterogenin regioisomer | CHEMBL552717)
Affinity DataKi:  5.30E+3nMAssay Description:Binding affinity to Bcl-xL by fluorescein-labeled Bak-BH3 peptide competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Institut De Chimie Des Substances Naturelles (Icsn)

Curated by ChEMBL
LigandPNGBDBM50022622(CHEMBL3299033)
Affinity DataKi:  5.90E+3nMAssay Description:Displacement of fluorescein-labeled BID from His-tagged MCL-1 (unknown origin) after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Institut De Chimie Des Substances Naturelles (Icsn)

Curated by ChEMBL
LigandPNGBDBM50295299(1-O-[alpha-L-(Rhamnopyranosyl]-23-acetoxy-3beta-ac...)
Affinity DataKi:  7.20E+3nMAssay Description:Binding affinity to Bcl-xL by fluorescein-labeled Bak-BH3 peptide competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Institut De Chimie Des Substances Naturelles (Icsn)

Curated by ChEMBL
LigandPNGBDBM50295300(icterogenin | CHEMBL554122)
Affinity DataKi:  7.60E+3nMAssay Description:Binding affinity to Bcl-xL by fluorescein-labeled Bak-BH3 peptide competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Institut De Chimie Des Substances Naturelles (Icsn)

Curated by ChEMBL
LigandPNGBDBM50022568(CHEMBL3298853)
Affinity DataKi:  1.26E+4nMAssay Description:Displacement of fluorescein-labeled BAK from His-tagged BCL-XL (unknown origin) after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Institut De Chimie Des Substances Naturelles (Icsn)

Curated by ChEMBL
LigandPNGBDBM50022568(CHEMBL3298853)
Affinity DataKi:  1.30E+4nMAssay Description:Displacement of fluorescein-labeled BID from His-tagged MCL-1 (unknown origin) after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Institut De Chimie Des Substances Naturelles (Icsn)

Curated by ChEMBL
LigandPNGBDBM50022567(CHEMBL3298852)
Affinity DataKi:  1.40E+4nMAssay Description:Displacement of fluorescein-labeled BID from His-tagged MCL-1 (unknown origin) after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Institut De Chimie Des Substances Naturelles (Icsn)

Curated by ChEMBL
LigandPNGBDBM50295301(23-O-[alpha-L-(2',4'-Diacetylrhamnopyranosyl]imber...)
Affinity DataKi:  1.41E+4nMAssay Description:Binding affinity to Bcl-xL by fluorescein-labeled Bak-BH3 peptide competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Institut De Chimie Des Substances Naturelles (Icsn)

Curated by ChEMBL
LigandPNGBDBM50295302(23-acetoxy-3beta-acetylimberbic acid | CHEMBL53990...)
Affinity DataKi:  1.78E+4nMAssay Description:Binding affinity to Bcl-xL by fluorescein-labeled Bak-BH3 peptide competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Institut De Chimie Des Substances Naturelles (Icsn)

Curated by ChEMBL
LigandPNGBDBM50022567(CHEMBL3298852)
Affinity DataKi:  1.92E+4nMAssay Description:Displacement of fluorescein-labeled BAK from His-tagged BCL-XL (unknown origin) after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Institut De Chimie Des Substances Naturelles (Icsn)

Curated by ChEMBL
LigandPNGBDBM50022622(CHEMBL3299033)
Affinity DataKi:  1.94E+4nMAssay Description:Displacement of fluorescein-labeled BAK from His-tagged BCL-XL (unknown origin) after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Institut De Chimie Des Substances Naturelles (Icsn)

Curated by ChEMBL
LigandPNGBDBM21447(4-(4-{[2-(4-chlorophenyl)phenyl]methyl}piperazin-1...)
Affinity DataKi:  2.08E+4nMAssay Description:Displacement of fluorescein-labeled BID from His-tagged MCL-1 (unknown origin) after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Institut De Chimie Des Substances Naturelles (Icsn)

Curated by ChEMBL
LigandPNGBDBM50022566(CHEMBL3298851)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of fluorescein-labeled BAK from His-tagged BCL-XL (unknown origin) after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Institut De Chimie Des Substances Naturelles (Icsn)

Curated by ChEMBL
LigandPNGBDBM50295303(23-Acetoxyimberbic acid 29-methyl ester | CHEMBL55...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity to Bcl-xL by fluorescein-labeled Bak-BH3 peptide competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Institut De Chimie Des Substances Naturelles (Icsn)

Curated by ChEMBL
LigandPNGBDBM50295304(23-O-[alpha-L-(3',4'-Diacetylrhamnopyranosyl]-3bet...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity to Bcl-xL by fluorescein-labeled Bak-BH3 peptide competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Institut De Chimie Des Substances Naturelles (Icsn)

Curated by ChEMBL
LigandPNGBDBM50022583(CHEMBL3298854)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of fluorescein-labeled BAK from His-tagged BCL-XL (unknown origin) after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Institut De Chimie Des Substances Naturelles (Icsn)

Curated by ChEMBL
LigandPNGBDBM50295305(23-O-[alpha-L-(4'-Acetylrhamnopyranosyl]-3beta-ace...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity to Bcl-xL by fluorescein-labeled Bak-BH3 peptide competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Institut De Chimie Des Substances Naturelles (Icsn)

Curated by ChEMBL
LigandPNGBDBM50022655(CHEMBL3299034)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of fluorescein-labeled BAK from His-tagged BCL-XL (unknown origin) after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
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