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Target5-hydroxytryptamine receptor 3A/3B(Rat)
Solvay Duphar

Curated by ChEMBL
LigandPNGBDBM50042715(1-(5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-...)
Affinity DataKi:  0.0750nMAssay Description:The binding affinity of the compound was measured on histamine H1 receptor using [3H]- mepyramine as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Solvay Duphar

Curated by ChEMBL
LigandPNGBDBM50231569(Cilansetron | KC-9946)
Affinity DataKi:  0.190nMAssay Description:The binding affinity was measured on 5-hydroxytryptamine 3 receptor using [3H]GR-65630 as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Solvay Duphar

Curated by ChEMBL
LigandPNGBDBM50042718(1-(3,4-Dihydro-5-thia-2a-aza-acenaphthylen-1-yl)-3...)
Affinity DataKi:  0.190nMAssay Description:The binding affinity of the compound was measured on alpha2-adrenergic receptor using [3H]- clonidine as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Solvay Duphar

Curated by ChEMBL
LigandPNGBDBM50042714(9-(2-Methyl-imidazol-1-ylmethyl)-4,5,8,9-tetrahydr...)
Affinity DataKi:  0.230nMAssay Description:Displacement of [3H]GR-65630 binding to 5-hydroxytryptamine 3 receptor in rat brain cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Solvay Duphar

Curated by ChEMBL
LigandPNGBDBM50042712(10-(2-Methyl-imidazol-1-ylmethyl)-5,6,9,10-tetrahy...)
Affinity DataKi:  0.25nMAssay Description:Displacement of [3H]- GR-65,630 binding to 5-hydroxytryptamine 3 receptor in rat brain cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Solvay Duphar

Curated by ChEMBL
LigandPNGBDBM50042713(3-(5-Methyl-1H-imidazol-4-yl)-1-(1-methyl-1H-indol...)
Affinity DataKi:  0.280nMAssay Description:The binding affinity of the compound was measured on glycine receptor using [3H]- strychnine as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Solvay Duphar

Curated by ChEMBL
LigandPNGBDBM50042720(3-(5-Methyl-1H-imidazol-4-yl)-1-(4,5,6,7-tetrahydr...)
Affinity DataKi:  0.330nMAssay Description:The binding affinity of the compound was measured on muscarine M1 receptor using [3H]- pirenzepine as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(pigeon)
Cns-Pharmacology

Curated by PDSP Ki Database
LigandPNGBDBM86708(CAS_146714-97-8 | CHEMBL31354 | CHEMBL514874 | CHE...)
Affinity DataKi:  0.5nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Solvay Duphar

Curated by ChEMBL
LigandPNGBDBM50042711(11-(2-Methyl-imidazol-1-ylmethyl)-4,5,6,7,10,11-he...)
Affinity DataKi:  0.640nMAssay Description:The binding affinity of the compound was measured on dopamine receptor D1 using [3H]- dopamine as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Solvay Duphar

Curated by ChEMBL
LigandPNGBDBM50042711(11-(2-Methyl-imidazol-1-ylmethyl)-4,5,6,7,10,11-he...)
Affinity DataKi:  0.640nMAssay Description:The binding affinity of the compound was measured on 5-hydroxytryptamine 1C receptor using [3H]- serotonin as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(pigeon)
Cns-Pharmacology

Curated by PDSP Ki Database
LigandPNGBDBM82517(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Affinity DataKi:  0.700nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(pigeon)
Cns-Pharmacology

Curated by PDSP Ki Database
LigandPNGBDBM85079(2-[4-[4-[(7-Chloro-2,3-dihydro-1,4-benzodioxin)-5-...)
Affinity DataKi:  0.700nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Solvay Duphar

Curated by ChEMBL
LigandPNGBDBM50042711(11-(2-Methyl-imidazol-1-ylmethyl)-4,5,6,7,10,11-he...)
Affinity DataKi:  0.75nMAssay Description:Displacement of [3H]- GR-65,630 binding to 5-hydroxytryptamine 3 receptor in rat brain cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Solvay Duphar

Curated by ChEMBL
LigandPNGBDBM50042719(8-(2-Methyl-imidazol-1-ylmethyl)-1,2,9,10-tetrahyd...)
Affinity DataKi:  0.770nMAssay Description:Displacement of [3H]- GR-65,630 binding to 5-hydroxytryptamine 3 receptor in rat brain cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Solvay Duphar

Curated by ChEMBL
LigandPNGBDBM50000483((BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid ...)
Affinity DataKi:  0.780nMAssay Description:Displacement of [3H]- GR-65,630 binding to 5-hydroxytryptamine 3 receptor in rat brain cortical membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Solvay Duphar

Curated by ChEMBL
LigandPNGBDBM50042712(10-(2-Methyl-imidazol-1-ylmethyl)-5,6,9,10-tetrahy...)
Affinity DataKi:  1.10nMAssay Description:The binding affinity of the compound was measured on mu-opiate receptor using [3H]- naloxone as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Solvay Duphar

Curated by ChEMBL
LigandPNGBDBM50042712(10-(2-Methyl-imidazol-1-ylmethyl)-5,6,9,10-tetrahy...)
Affinity DataKi:  1.10nMAssay Description:The binding affinity of the compound was measured on kappa-opiate receptor using [3H]- EKC as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Solvay Duphar

Curated by ChEMBL
LigandPNGBDBM50042717(12-(2-methyl-1H-1-imidazolylmethyl)-5,6,7,8,10,11,...)
Affinity DataKi:  1.10nMAssay Description:The binding affinity of the compound was measured on 5-hydroxytryptamine 3 receptor using [3H]- GR-65,630 as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Solvay Duphar

Curated by ChEMBL
LigandPNGBDBM50042716(8-(2-Methyl-imidazol-1-ylmethyl)-1,2,9,10-tetrahyd...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]GR-65630 binding to 5-hydroxytryptamine 3 receptor in rat brain cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(pigeon)
Cns-Pharmacology

Curated by PDSP Ki Database
LigandPNGBDBM82517(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Affinity DataKi:  1.30nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Solvay Duphar

Curated by ChEMBL
LigandPNGBDBM85330(CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...)
Affinity DataKi:  1.60nMAssay Description:The binding affinity of the compound was measured on imidazoline I2 receptor using [3H]- indazoxan as radioligand.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Solvay Duphar

Curated by ChEMBL
LigandPNGBDBM85330(CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...)
Affinity DataKi:  1.60nMAssay Description:The binding affinity was measured on muscarine M2 receptor using [3H]- N-Me-SCOPOL as radioligand.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Solvay Duphar

Curated by ChEMBL
LigandPNGBDBM85330(CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]- GR-65,630 binding to 5-hydroxytryptamine 3 receptor in rat brain cortical membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(pigeon)
Cns-Pharmacology

Curated by PDSP Ki Database
LigandPNGBDBM82564(CAS_132787 | NSC_132787 | S 15535)
Affinity DataKi:  1.90nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(pigeon)
Cns-Pharmacology

Curated by PDSP Ki Database
LigandPNGBDBM85079(2-[4-[4-[(7-Chloro-2,3-dihydro-1,4-benzodioxin)-5-...)
Affinity DataKi:  5.20nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(pigeon)
Cns-Pharmacology

Curated by PDSP Ki Database
LigandPNGBDBM85079(2-[4-[4-[(7-Chloro-2,3-dihydro-1,4-benzodioxin)-5-...)
Affinity DataKi:  6.40nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(pigeon)
Cns-Pharmacology

Curated by PDSP Ki Database
LigandPNGBDBM82517(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Affinity DataKi:  9.30nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(pigeon)
Cns-Pharmacology

Curated by PDSP Ki Database
LigandPNGBDBM82369(CAS_133025-23-7 | WAY 100,135 | WAY 100135)
Affinity DataKi:  10nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(pigeon)
Cns-Pharmacology

Curated by PDSP Ki Database
LigandPNGBDBM85079(2-[4-[4-[(7-Chloro-2,3-dihydro-1,4-benzodioxin)-5-...)
Affinity DataKi:  11nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(pigeon)
Cns-Pharmacology

Curated by PDSP Ki Database
LigandPNGBDBM82517(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Affinity DataKi:  14nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(pigeon)
Cns-Pharmacology

Curated by PDSP Ki Database
LigandPNGBDBM50019443(1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...)
Affinity DataKi:  47nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(pigeon)
Cns-Pharmacology

Curated by PDSP Ki Database
LigandPNGBDBM86708(CAS_146714-97-8 | CHEMBL31354 | CHEMBL514874 | CHE...)
Affinity DataKi:  78nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(pigeon)
Cns-Pharmacology

Curated by PDSP Ki Database
LigandPNGBDBM86708(CAS_146714-97-8 | CHEMBL31354 | CHEMBL514874 | CHE...)
Affinity DataKi:  120nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(pigeon)
Cns-Pharmacology

Curated by PDSP Ki Database
LigandPNGBDBM82564(CAS_132787 | NSC_132787 | S 15535)
Affinity DataKi:  132nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(pigeon)
Cns-Pharmacology

Curated by PDSP Ki Database
LigandPNGBDBM82564(CAS_132787 | NSC_132787 | S 15535)
Affinity DataKi:  144nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(pigeon)
Cns-Pharmacology

Curated by PDSP Ki Database
LigandPNGBDBM82517(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Affinity DataKi:  219nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(pigeon)
Cns-Pharmacology

Curated by PDSP Ki Database
LigandPNGBDBM85079(2-[4-[4-[(7-Chloro-2,3-dihydro-1,4-benzodioxin)-5-...)
Affinity DataKi:  240nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(pigeon)
Cns-Pharmacology

Curated by PDSP Ki Database
LigandPNGBDBM82369(CAS_133025-23-7 | WAY 100,135 | WAY 100135)
Affinity DataKi:  245nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C isoform A(pigeon)
Cns-Pharmacology

Curated by PDSP Ki Database
LigandPNGBDBM86708(CAS_146714-97-8 | CHEMBL31354 | CHEMBL514874 | CHE...)
Affinity DataKi:  282nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(pigeon)
Cns-Pharmacology

Curated by PDSP Ki Database
LigandPNGBDBM82517(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Affinity DataKi:  316nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
Solvay Duphar

Curated by ChEMBL
LigandPNGBDBM50231569(Cilansetron | KC-9946)
Affinity DataKi:  340nMAssay Description:The binding affinity of the compound was measured on delta-opiate receptor using [3H]- dadle as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(pigeon)
Cns-Pharmacology

Curated by PDSP Ki Database
LigandPNGBDBM86708(CAS_146714-97-8 | CHEMBL31354 | CHEMBL514874 | CHE...)
Affinity DataKi:  370nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(pigeon)
Cns-Pharmacology

Curated by PDSP Ki Database
LigandPNGBDBM82517(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Affinity DataKi:  617nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C isoform A(pigeon)
Cns-Pharmacology

Curated by PDSP Ki Database
LigandPNGBDBM82517(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Affinity DataKi:  630nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Rat)
Solvay Duphar

Curated by ChEMBL
LigandPNGBDBM85330(CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...)
Affinity DataKi:  680nMAssay Description:The binding affinity of the compound was measured on cholecystokinin type B receptor using [3H]- CCK-8 as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
Solvay Duphar

Curated by ChEMBL
LigandPNGBDBM85330(CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...)
Affinity DataKi:  680nMAssay Description:The binding affinity of the compound was measured on sigma receptor using [3H]- (+)-3-PPP as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C isoform A(pigeon)
Cns-Pharmacology

Curated by PDSP Ki Database
LigandPNGBDBM85079(2-[4-[4-[(7-Chloro-2,3-dihydro-1,4-benzodioxin)-5-...)
Affinity DataKi:  750nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(pigeon)
Cns-Pharmacology

Curated by PDSP Ki Database
LigandPNGBDBM82369(CAS_133025-23-7 | WAY 100,135 | WAY 100135)
Affinity DataKi:  790nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(pigeon)
Cns-Pharmacology

Curated by PDSP Ki Database
LigandPNGBDBM82517(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Affinity DataKi:  794nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(pigeon)
Cns-Pharmacology

Curated by PDSP Ki Database
LigandPNGBDBM85079(2-[4-[4-[(7-Chloro-2,3-dihydro-1,4-benzodioxin)-5-...)
Affinity DataKi:  890nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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