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TargetCysteinyl leukotriene receptor 1(Guinea pig)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50296089(2-(2-(5-(3-(2-(6,7-difluoroquinolin-2-yl)vinyl)ben...)
Affinity DataIC50:  0.910nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCysteinyl leukotriene receptor 1(Guinea pig)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50296106(3-(5-(3-(2-(6,7-difluoroquinolin-2-yl)vinyl)benzyl...)
Affinity DataIC50:  1nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCysteinyl leukotriene receptor 1(Guinea pig)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50296095(2-(2-(1H-tetrazol-5-yl)ethyl)-9-(3-(2-(7-chloroqui...)
Affinity DataIC50:  1.20nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCysteinyl leukotriene receptor 1(Guinea pig)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50296115(3-(5-(3-(2-(6,7-difluoroquinolin-2-yl)vinyl)benzyl...)
Affinity DataIC50:  1.20nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCysteinyl leukotriene receptor 1(Guinea pig)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50296092(3-(5-(3-((7-chloroquinolin-2-yl)ethynyl)benzyl)-3,...)
Affinity DataIC50:  1.30nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCysteinyl leukotriene receptor 1(Guinea pig)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50296105(3-(5-(3-(2-(7-chloro-6-fluoroquinolin-2-yl)vinyl)b...)
Affinity DataIC50:  1.70nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCysteinyl leukotriene receptor 1(Guinea pig)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50296114(3-(5-(3-(2-(6,7-difluoroquinolin-2-yl)vinyl)benzyl...)
Affinity DataIC50:  2.5nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCysteinyl leukotriene receptor 1(Guinea pig)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50296088(4-((5-(3-(2-(6,7-difluoroquinolin-2-yl)vinyl)benzy...)
Affinity DataIC50:  3nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCysteinyl leukotriene receptor 1(Guinea pig)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50296085(2-(1-((5-(3-(2-(7-chloroquinolin-2-yl)vinyl)benzyl...)
Affinity DataIC50:  3.20nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCysteinyl leukotriene receptor 1(Guinea pig)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50296103(3-(5-(3-(2-(7-fluoroquinolin-2-yl)vinyl)benzyl)-3,...)
Affinity DataIC50:  3.40nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCysteinyl leukotriene receptor 1(Guinea pig)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50296102(4-(1-(3-(2-(7-chloroquinolin-2-yl)vinyl)benzyl)-2-...)
Affinity DataIC50:  3.40nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCysteinyl leukotriene receptor 1(Guinea pig)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50296087(4-(5-(3-((E)-2-(7-chloroquinolin-2-yl)vinyl)benzyl...)
Affinity DataIC50:  4.10nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCysteinyl leukotriene receptor 1(Guinea pig)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50296101(4-(1-(3-(2-(7-chloroquinolin-2-yl)vinyl)benzyl)-1H...)
Affinity DataIC50:  4.40nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCysteinyl leukotriene receptor 1(Guinea pig)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50296113(3-(5-(3-(2-(6,7-difluoroquinolin-2-yl)vinyl)benzyl...)
Affinity DataIC50:  4.5nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCysteinyl leukotriene receptor 1(Guinea pig)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50296099(3-(9-(3-(2-(7-chloroquinolin-2-yl)vinyl)benzyl)-9H...)
Affinity DataIC50:  4.80nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCysteinyl leukotriene receptor 1(Guinea pig)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50296100(2-(9-(3-(2-(7-chloroquinolin-2-yl)vinyl)benzyl)-2,...)
Affinity DataIC50:  4.90nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCysteinyl leukotriene receptor 1(Guinea pig)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50296112(3-(5-(3-(2-(7-chloroquinolin-2-yl)vinyl)benzyl)-8-...)
Affinity DataIC50:  7.5nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCysteinyl leukotriene receptor 1(Guinea pig)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50296097(3-((2-(1-(3-(2-(7-chloroquinolin-2-yl)vinyl)benzyl...)
Affinity DataIC50:  9.30nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCysteinyl leukotriene receptor 1(Guinea pig)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50296096(3-(5-(3-(2-(7-chloroquinolin-2-yl)vinyl)benzyl)-3,...)
Affinity DataIC50:  12nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCysteinyl leukotriene receptor 1(Guinea pig)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50296116(3-(5-((2-(7-chloroquinolin-2-yl)benzofuran-5-yl)me...)
Affinity DataIC50:  14nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCysteinyl leukotriene receptor 1(Guinea pig)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50296094(4-(9-(3-(2-(7-chloroquinolin-2-yl)vinyl)benzyl)-4,...)
Affinity DataIC50:  15nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCysteinyl leukotriene receptor 1(Guinea pig)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50296084(5-(5-(3-(2-(7-chloroquinolin-2-yl)vinyl)benzyl)-3,...)
Affinity DataIC50:  16nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCysteinyl leukotriene receptor 1(Guinea pig)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50296081(3-(5-(3-(2-(7-chloroquinolin-2-yl)vinyl)benzyl)-3,...)
Affinity DataIC50:  16nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCysteinyl leukotriene receptor 1(Guinea pig)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50296111(3-(5-(3-(2-(7-chloroquinolin-2-yl)vinyl)benzyl)-7-...)
Affinity DataIC50:  16nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCysteinyl leukotriene receptor 1(Guinea pig)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50296082(2-(5-(3-(2-(7-chloroquinolin-2-yl)vinyl)benzyl)-3,...)
Affinity DataIC50:  17nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCysteinyl leukotriene receptor 1(Guinea pig)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50296093(3-(9-(3-(2-(7-chloroquinolin-2-yl)vinyl)benzyl)-4,...)
Affinity DataIC50:  20nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCysteinyl leukotriene receptor 1(Guinea pig)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50296104(3-(5-(3-(2-(6,7-dichloroquinolin-2-yl)vinyl)benzyl...)
Affinity DataIC50:  21nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCysteinyl leukotriene receptor 1(Guinea pig)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50296091(3-(5-(3-(2-(7-chloroquinolin-2-yl)ethyl)benzyl)-3,...)
Affinity DataIC50:  25nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCysteinyl leukotriene receptor 1(Guinea pig)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50296086(3-(5-(3-(2-(7-chloroquinolin-2-yl)vinyl)benzyl)-3,...)
Affinity DataIC50:  26nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCysteinyl leukotriene receptor 1(Guinea pig)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50296083(4-(5-(3-(2-(7-chloroquinolin-2-yl)vinyl)benzyl)-3,...)
Affinity DataIC50:  30nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCysteinyl leukotriene receptor 1(Guinea pig)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50296107(3-(5-(3-(2-(4-tert-butylthiazol-2-yl)vinyl)benzyl)...)
Affinity DataIC50:  37nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCysteinyl leukotriene receptor 1(Guinea pig)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50296090(3-(5-(3-((7-chloroquinolin-2-yl)methoxy)benzyl)-3,...)
Affinity DataIC50:  42nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCysteinyl leukotriene receptor 1(Guinea pig)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50296109(3-(5-(3-(2-(2,3-dichlorothieno[3,2-b]pyridin-5-yl)...)
Affinity DataIC50:  50nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCysteinyl leukotriene receptor 1(Guinea pig)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50296098(3-(((1-(3-(2-(7-chloroquinolin-2-yl)vinyl)benzyl)-...)
Affinity DataIC50:  61nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCysteinyl leukotriene receptor 1(Guinea pig)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50296108(3-(5-(3-(2-(5-chlorobenzo[d]thiazol-2-yl)vinyl)ben...)
Affinity DataIC50:  112nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCysteinyl leukotriene receptor 1(Guinea pig)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50296110(3-(5-(3-(2-(7-chloroquinolin-2-yl)vinyl)benzyl)-6-...)
Affinity DataIC50:  150nMAssay Description:Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlycogen synthase kinase-3 beta(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50426172(CHEMBL483841 | Ircinin 1)
Affinity DataIC50:  794nMAssay Description:Inhibition of human recombinant GSK-3beta using GS2 peptide as substrate and [gamma33P]-ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlycogen synthase kinase-3 beta(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50426172(CHEMBL483841 | Ircinin 1)
Affinity DataIC50:  794nMAssay Description:Inhibition of human recombinant GSK-3beta using GS2 peptide as substrate and [gamma33P]-ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Instituto De Qu£Mica M£Dica (Csic)

Curated by ChEMBL
LigandPNGBDBM50359737(CHEMBL1927722)
Affinity DataIC50:  1.04E+3nMAssay Description:Inhibition of PDE7A assessed as hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlycogen synthase kinase-3 alpha(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50401965(PALINURIN)
Affinity DataIC50:  1.62E+3nMAssay Description:Inhibition of human recombinant GSK-3alpha using GS2 peptide as substrate and [gamma33P]-ATP after 12 mins by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetGlycogen synthase kinase-3 alpha(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50401965(PALINURIN)
Affinity DataIC50:  1.62E+3nMAssay Description:Inhibition of human recombinant GSK-3alpha using GS2 peptide as substrate and [gamma33P]-ATP after 12 mins by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Instituto De Qu£Mica M£Dica (Csic)

Curated by ChEMBL
LigandPNGBDBM50359736(CHEMBL1927721)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of PDE7A assessed as hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Instituto De Qu£Mica M£Dica (Csic)

Curated by ChEMBL
LigandPNGBDBM50359739(CHEMBL1927730)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of PDE7A assessed as hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlycogen synthase kinase-3 beta(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50401965(PALINURIN)
Affinity DataIC50:  1.91E+3nMAssay Description:Inhibition of human recombinant GSK-3beta using GS2 peptide as substrate and [gamma33P]-ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetGlycogen synthase kinase-3 beta(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50401965(PALINURIN)
Affinity DataIC50:  1.91E+3nMAssay Description:Inhibition of human recombinant GSK-3beta using GS2 peptide as substrate and [gamma33P]-ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetGlycogen synthase kinase-3 beta(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50426171(CHEMBL483842 | Ircinin 2)
Affinity DataIC50:  2.34E+3nMAssay Description:Inhibition of human recombinant GSK-3beta using GS2 peptide as substrate and [gamma33P]-ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlycogen synthase kinase-3 beta(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50426171(CHEMBL483842 | Ircinin 2)
Affinity DataIC50:  2.34E+3nMAssay Description:Inhibition of human recombinant GSK-3beta using GS2 peptide as substrate and [gamma33P]-ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlycogen synthase kinase-3 beta(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50426173(CHEMBL219346)
Affinity DataIC50:  5.75E+3nMAssay Description:Inhibition of human recombinant GSK-3beta using GS2 peptide as substrate and [gamma33P]-ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlycogen synthase kinase-3 beta(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50426173(CHEMBL219346)
Affinity DataIC50:  5.75E+3nMAssay Description:Inhibition of human recombinant GSK-3beta using GS2 peptide as substrate and [gamma33P]-ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Instituto De Qu£Mica M£Dica (Csic)

Curated by ChEMBL
LigandPNGBDBM50359738(CHEMBL1927729)
Affinity DataIC50:  6.10E+3nMAssay Description:Inhibition of PDE7A assessed as hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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