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TargetBeta-1 adrenergic receptor(Guinea pig)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50007476(CHEMBL266619 | 4-(3-tert-Butylamino-2-hydroxy-prop...)
Affinity DataEC50:  4.70nMAssay Description:Agonistic activity (beta-1 adrenergic receptor) for the percent maximal increase in contraction rate of isolated guinea pig atriaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Guinea pig)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50007478(CHEMBL10494 | 4-(3-tert-Butylamino-2-hydroxy-propo...)
Affinity DataEC50:  175nMAssay Description:Agonistic activity (beta-1 adrenergic receptor) for the percent maximal increase in contraction rate of isolated guinea pig atriaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Guinea pig)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM25392(Isoproterenol,(+) | CHEMBL434 | 4-[1-hydroxy-2-(pr...)
Affinity DataEC50:  6nMAssay Description:Agonistic activity (beta-1 adrenergic receptor) for the percent maximal increase in contraction rate of isolated guinea pig atriaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Guinea pig)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM25392(Isoproterenol,(+) | CHEMBL434 | 4-[1-hydroxy-2-(pr...)
Affinity DataEC50:  58nMAssay Description:Agonistic activity (beta2- adrenergic) for the percent maximal relaxation of isolated guinea pig tracheaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Guinea pig)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50007476(CHEMBL266619 | 4-(3-tert-Butylamino-2-hydroxy-prop...)
Affinity DataEC50:  130nMAssay Description:Agonistic activity (beta2- adrenergic) for the percent maximal relaxation of isolated guinea pig tracheaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Guinea pig)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50007477(CHEMBL10453 | 4-(3-tert-Butylamino-2-hydroxy-propo...)
Affinity DataEC50:  8.60nMAssay Description:Agonistic activity (beta-1 adrenergic receptor) for the percent maximal increase in contraction rate of isolated guinea pig atriaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Guinea pig)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50007477(CHEMBL10453 | 4-(3-tert-Butylamino-2-hydroxy-propo...)
Affinity DataEC50:  38nMAssay Description:Agonistic activity (beta2- adrenergic) for the percent maximal relaxation of isolated guinea pig tracheaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50007477(CHEMBL10453 | 4-(3-tert-Butylamino-2-hydroxy-propo...)
Affinity DataEC50:  9.20nMAssay Description:Beta adrenergic receptor agonistic activity for the stimulation of accumulation of cyclic AMP in cultured C6 glioma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50007476(CHEMBL266619 | 4-(3-tert-Butylamino-2-hydroxy-prop...)
Affinity DataEC50:  8.20nMAssay Description:Beta adrenergic receptor agonistic activity for the stimulation of accumulation of cyclic AMP in cultured C6 glioma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM25392(Isoproterenol,(+) | CHEMBL434 | 4-[1-hydroxy-2-(pr...)
Affinity DataEC50:  7nMAssay Description:Beta adrenergic receptor agonistic activity for the stimulation of accumulation of cyclic AMP in cultured C6 glioma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50019061(CHEMBL281232 | 4-(2-Amino-1-hydroxy-ethyl)-5-fluor...)
Affinity DataEC50:  5.00E+3nMAssay Description:Agonist activity at alpha-adrenergic receptor in Sprague-Dawley rat cerebral cortex assessed as [3H]cAMP accumulation by liquid scintillation spectro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50019060(CHEMBL287587 | 4-(2-Amino-1-hydroxy-ethyl)-3-fluor...)
Affinity DataEC50:  2.00E+3nMAssay Description:Displacement of [3H]dihydroalprenolol from beta-adrenergic receptor in Sprague-Dawley rat cerebral cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM35234(Noradrenaline,(+) | NOREPINEPHRINE | DL-[7-3H]nore...)
Affinity DataEC50:  5.00E+3nMAssay Description:Agonist activity at beta-adrenergic receptor in Sprague-Dawley rat cerebral cortex assessed as [3H]cAMP accumulation by liquid scintillation spectros...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
LigandPNGBDBM35234(Noradrenaline,(+) | NOREPINEPHRINE | DL-[7-3H]nore...)
Affinity DataEC50:  5.00E+3nMAssay Description:Agonist activity at alpha-adrenergic receptor in Sprague-Dawley rat cerebral cortex assessed as [3H]cAMP accumulation by liquid scintillation spectro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
LigandPNGBDBM50019060(CHEMBL287587 | 4-(2-Amino-1-hydroxy-ethyl)-3-fluor...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at alpha-adrenergic receptor in Sprague-Dawley rat cerebral cortex assessed as [3H]cAMP accumulation by liquid scintillation spectro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
LigandPNGBDBM50042998(5-(2-Amino-1-hydroxy-ethyl)-3-fluoro-benzene-1,2-d...)
Affinity DataEC50:  5.00E+3nMAssay Description:Agonist activity at alpha-adrenergic receptor in Sprague-Dawley rat cerebral cortex assessed as [3H]cAMP accumulation by liquid scintillation spectro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50042998(5-(2-Amino-1-hydroxy-ethyl)-3-fluoro-benzene-1,2-d...)
Affinity DataEC50:  2.00E+3nMAssay Description:Agonist activity at beta-adrenergic receptor in Sprague-Dawley rat cerebral cortex assessed as [3H]cAMP accumulation by liquid scintillation spectros...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50019061(CHEMBL281232 | 4-(2-Amino-1-hydroxy-ethyl)-5-fluor...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at beta-adrenergic receptor in Sprague-Dawley rat cerebral cortex assessed as [3H]cAMP accumulation by liquid scintillation spectros...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
LigandPNGBDBM50042998(5-(2-Amino-1-hydroxy-ethyl)-3-fluoro-benzene-1,2-d...)
Affinity DataEC50:  1.50E+4nMAssay Description:Displacement of [3H]WB4101 from alpha-adrenergic receptor in Sprague-Dawley rat cerebral cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
LigandPNGBDBM50019061(CHEMBL281232 | 4-(2-Amino-1-hydroxy-ethyl)-5-fluor...)
Affinity DataEC50:  3.00E+3nMAssay Description:Displacement of [3H]WB4101 from alpha-adrenergic receptor in Sprague-Dawley rat cerebral cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50019061(CHEMBL281232 | 4-(2-Amino-1-hydroxy-ethyl)-5-fluor...)
Affinity DataEC50: >1.00E+5nMAssay Description:Displacement of [3H]dihydroalprenolol from beta-adrenergic receptor in Sprague-Dawley rat cerebral cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
LigandPNGBDBM35234(Noradrenaline,(+) | NOREPINEPHRINE | DL-[7-3H]nore...)
Affinity DataEC50:  3.00E+3nMAssay Description:Displacement of [3H]WB4101 from alpha-adrenergic receptor in Sprague-Dawley rat cerebral cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM35234(Noradrenaline,(+) | NOREPINEPHRINE | DL-[7-3H]nore...)
Affinity DataEC50:  800nMAssay Description:Displacement of [3H]dihydroalprenolol from beta-adrenergic receptor in Sprague-Dawley rat cerebral cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
LigandPNGBDBM50019060(CHEMBL287587 | 4-(2-Amino-1-hydroxy-ethyl)-3-fluor...)
Affinity DataEC50: >1.00E+5nMAssay Description:Displacement of [3H]WB4101 from alpha-adrenergic receptor in Sprague-Dawley rat cerebral cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50019060(CHEMBL287587 | 4-(2-Amino-1-hydroxy-ethyl)-3-fluor...)
Affinity DataEC50:  5.00E+3nMAssay Description:Agonist activity at beta-adrenergic receptor in Sprague-Dawley rat cerebral cortex assessed as [3H]cAMP accumulation by liquid scintillation spectros...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50042998(5-(2-Amino-1-hydroxy-ethyl)-3-fluoro-benzene-1,2-d...)
Affinity DataEC50:  4.00E+3nMAssay Description:Displacement of [3H]dihydroalprenolol from beta-adrenergic receptor in Sprague-Dawley rat cerebral cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50064609(Acetic acid 8-aza-bicyclo[3.2.1]oct-6-yl ester | 6...)
Affinity DataEC50:  23nMAssay Description:Inhibitory activity against stimulation of [3H]inositol monophosphate accumulation in [3H]inositol-labelled CHO transfected cells mediated by Muscari...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50004656((2-Hydroxyethyl)trimethyl ammonium chloride carbam...)
Affinity DataEC50:  650nMAssay Description:Inhibitory activity against stimulation of [3H]inositol monophosphate accumulation in [3H]inositol-labelled CHO transfected cells mediated by Muscari...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50006243(CHEMBL292911 | ((2S,4R,5S)-4-Hydroxy-5-methyl-tetr...)
Affinity DataEC50:  219nMAssay Description:Inhibitory activity against stimulation of [3H]inositol monophosphate accumulation in [3H]inositol-labelled CHO transfected cells mediated by Muscari...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50064609(Acetic acid 8-aza-bicyclo[3.2.1]oct-6-yl ester | 6...)
Affinity DataEC50:  3.60nMAssay Description:Inhibitory activity against stimulation of [3H]inositol monophosphate accumulation in [3H]inositol-labelled CHO transfected cells mediated by Muscari...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50004656((2-Hydroxyethyl)trimethyl ammonium chloride carbam...)
Affinity DataEC50:  480nMAssay Description:Inhibitory activity against stimulation of [3H]inositol monophosphate accumulation in [3H]inositol-labelled CHO transfected cells mediated by Muscari...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM48918(2-acetyloxypropyl(trimethyl)azanium;chloride | SMR...)
Affinity DataEC50:  120nMAssay Description:Inhibitory activity against stimulation of [3H]inositol monophosphate accumulation in [3H]inositol-labelled CHO transfected cells mediated by Muscari...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50006243(CHEMBL292911 | ((2S,4R,5S)-4-Hydroxy-5-methyl-tetr...)
Affinity DataEC50:  130nMAssay Description:Inhibitory activity against stimulation of [3H]inositol monophosphate accumulation in [3H]inositol-labelled CHO transfected cells mediated by Muscari...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM48918(2-acetyloxypropyl(trimethyl)azanium;chloride | SMR...)
Affinity DataEC50:  400nMAssay Description:Inhibitory activity against stimulation of [3H]inositol monophosphate accumulation in [3H]inositol-labelled CHO transfected cells mediated by Muscari...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50064609(Acetic acid 8-aza-bicyclo[3.2.1]oct-6-yl ester | 6...)
Affinity DataIC50: 11nMAssay Description:Inhibitory activity against [3H]-cyclic AMP accumulation in CHO transfected cells mediated by Muscarinic acetylcholine receptor M4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50064609(Acetic acid 8-aza-bicyclo[3.2.1]oct-6-yl ester | 6...)
Affinity DataIC50: 17nMAssay Description:Inhibitory activity against [3H]quinuclidinyl Benzilate binding to Muscarinic acetylcholine receptor M2 in the absence of GTPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50064609(Acetic acid 8-aza-bicyclo[3.2.1]oct-6-yl ester | 6...)
Affinity DataIC50: 17nMAssay Description:Inhibition of binding of 0.1 nM [3H]quinuclidinyl benzilate to Muscarinic acetylcholine receptor M2 in rat cerebral cortical membranes of transfected...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50064609(Acetic acid 8-aza-bicyclo[3.2.1]oct-6-yl ester | 6...)
Affinity DataIC50: 120nMAssay Description:Inhibition of binding of 0.1 nM [3H]quinuclidinyl benzilate to Muscarinic acetylcholine receptor M2 in rat cerebral cortical membranes of transfected...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50064609(Acetic acid 8-aza-bicyclo[3.2.1]oct-6-yl ester | 6...)
Affinity DataIC50: 120nMAssay Description:Inhibitory activity against [3H]quinuclidinyl Benzilate binding to Muscarinic acetylcholine receptor M2 in the presence of GTPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50004656((2-Hydroxyethyl)trimethyl ammonium chloride carbam...)
Affinity DataIC50: 130nMAssay Description:Inhibition of binding of 0.1 nM [3H]quinuclidinyl benzilate to Muscarinic acetylcholine receptor M2 in rat cerebral cortical membranes of transfected...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50004656((2-Hydroxyethyl)trimethyl ammonium chloride carbam...)
Affinity DataIC50: 130nMAssay Description:Inhibitory activity against [3H]quinuclidinyl Benzilate binding to Muscarinic acetylcholine receptor M2 in the absence of GTPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50004656((2-Hydroxyethyl)trimethyl ammonium chloride carbam...)
Affinity DataIC50: 130nMAssay Description:Inhibition of binding of 0.1 nM [3H]quinuclidinyl benzilate to Muscarinic acetylcholine receptor M2 in rat cerebral cortical membranes of transfected...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50004656((2-Hydroxyethyl)trimethyl ammonium chloride carbam...)
Affinity DataIC50: 230nMAssay Description:Inhibitory activity against [3H]-cyclic AMP accumulation in CHO transfected cells mediated by Muscarinic acetylcholine receptor M4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM48918(2-acetyloxypropyl(trimethyl)azanium;chloride | SMR...)
Affinity DataIC50: 380nMAssay Description:Inhibitory activity against [3H]quinuclidinyl Benzilate binding to Muscarinic acetylcholine receptor M2 in the absence of GTPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM48918(2-acetyloxypropyl(trimethyl)azanium;chloride | SMR...)
Affinity DataIC50: 380nMAssay Description:Inhibition of binding of 0.1 nM [3H]quinuclidinyl benzilate to Muscarinic acetylcholine receptor M2 in rat cerebral cortical membranes of transfected...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50006243(CHEMBL292911 | ((2S,4R,5S)-4-Hydroxy-5-methyl-tetr...)
Affinity DataIC50: 449nMAssay Description:Inhibitory activity against [3H]quinuclidinyl Benzilate binding to Muscarinic acetylcholine receptor M2 in the absence of GTPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50006243(CHEMBL292911 | ((2S,4R,5S)-4-Hydroxy-5-methyl-tetr...)
Affinity DataIC50: 470nMAssay Description:Inhibitory activity against [3H]-cyclic AMP accumulation in CHO transfected cells mediated by Muscarinic acetylcholine receptor M4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50006243(CHEMBL292911 | ((2S,4R,5S)-4-Hydroxy-5-methyl-tetr...)
Affinity DataIC50: 490nMAssay Description:Inhibition of binding of 0.1 nM [3H]quinuclidinyl benzilate to Muscarinic acetylcholine receptor M2 in rat cerebral cortical membranes of transfected...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM48918(2-acetyloxypropyl(trimethyl)azanium;chloride | SMR...)
Affinity DataIC50: 700nMAssay Description:Inhibitory activity against [3H]-cyclic AMP accumulation in CHO transfected cells mediated by Muscarinic acetylcholine receptor M4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50004656((2-Hydroxyethyl)trimethyl ammonium chloride carbam...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibitory activity against [3H]quinuclidinyl Benzilate binding to Muscarinic acetylcholine receptor M2 in the presence of GTPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
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