Report error Found 3911 with Last Name = 'pan' and Initial = 'p'
Affinity DataEC50: 35.6nMpH: 7.2 T: 2°CAssay Description:Inhibitors were assayed for the ability to inhibit [14C]AMG uptake in a protein-free buffer over a 2 h incubation period. The response curve was fitt...More data for this Ligand-Target Pair
Affinity DataEC50: 6.60nMpH: 7.2 T: 2°CAssay Description:Inhibitors were assayed for the ability to inhibit [14C]AMG uptake in a protein-free buffer over a 2 h incubation period. The response curve was fitt...More data for this Ligand-Target Pair
Affinity DataEC50: 9.20nMpH: 7.2 T: 2°CAssay Description:Inhibitors were assayed for the ability to inhibit [14C]AMG uptake in a protein-free buffer over a 2 h incubation period. The response curve was fitt...More data for this Ligand-Target Pair
Affinity DataEC50: 1.30E+3nMpH: 7.2 T: 2°CAssay Description:Inhibitors were assayed for the ability to inhibit [14C]AMG uptake in a protein-free buffer over a 2 h incubation period. The response curve was fitt...More data for this Ligand-Target Pair
Affinity DataEC50: 1.10nMpH: 7.2 T: 2°CAssay Description:Inhibitors were assayed for the ability to inhibit [14C]AMG uptake in a protein-free buffer over a 2 h incubation period. The response curve was fitt...More data for this Ligand-Target Pair
Affinity DataEC50: 330nMpH: 7.2 T: 2°CAssay Description:Inhibitors were assayed for the ability to inhibit [14C]AMG uptake in a protein-free buffer over a 2 h incubation period. The response curve was fitt...More data for this Ligand-Target Pair
Affinity DataEC50: 211nMpH: 7.2 T: 2°CAssay Description:Inhibitors were assayed for the ability to inhibit [14C]AMG uptake in a protein-free buffer over a 2 h incubation period. The response curve was fitt...More data for this Ligand-Target Pair
Affinity DataEC50: >8.00E+3nMpH: 7.2 T: 2°CAssay Description:Inhibitors were assayed for the ability to inhibit [14C]AMG uptake in a protein-free buffer over a 2 h incubation period. The response curve was fitt...More data for this Ligand-Target Pair
Affinity DataEC50: >8.00E+3nMpH: 7.2 T: 2°CAssay Description:Inhibitors were assayed for the ability to inhibit [14C]AMG uptake in a protein-free buffer over a 2 h incubation period. The response curve was fitt...More data for this Ligand-Target Pair
Affinity DataEC50: 1.39E+3nMpH: 7.2 T: 2°CAssay Description:Inhibitors were assayed for the ability to inhibit [14C]AMG uptake in a protein-free buffer over a 2 h incubation period. The response curve was fitt...More data for this Ligand-Target Pair
Affinity DataEC50: 100nMAssay Description:Agonist activity at human RXFP4 expressed in CHOK1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP accumulation preincubated ...More data for this Ligand-Target Pair
Affinity DataEC50: 800nMAssay Description:Agonist activity at human RXFP3 expressed in CHOK1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP accumulation preincubated ...More data for this Ligand-Target Pair
Affinity DataEC50: 1.30E+3nMAssay Description:Agonist activity at human RXFP3 expressed in CHOK1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP accumulation preincubated ...More data for this Ligand-Target Pair
Affinity DataEC50: 4nMAssay Description:Agonist activity at human RXFP4 expressed in CHOK1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP accumulation preincubated ...More data for this Ligand-Target Pair
Affinity DataEC50: 119nMAssay Description:Agonist activity at human RXFP3 expressed in CHOK1 cell membranes assessed as stimulation of [35S]-GTPgammaS binding after 3 hrs by scintillation cou...More data for this Ligand-Target Pair
Affinity DataEC50: 11nMAssay Description:Agonist activity at human RXFP4 expressed in CHOK1 cell membranes assessed as stimulation of [35S]-GTPgammaS binding after 3 hrs by scintillation cou...More data for this Ligand-Target Pair
Affinity DataEC50: 4.90E+3nMAssay Description:Agonist activity at human RXFP3/4 in human U2OS cells assessed as induction of beta-arrestin recruitment incubated for 1 hr by chemiluminescence base...More data for this Ligand-Target Pair
Affinity DataEC50: 2nMAssay Description:Agonist activity at human RXFP4 expressed in CHOK1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP accumulation preincubated ...More data for this Ligand-Target Pair
Affinity DataEC50: 2.70E+3nMAssay Description:Agonist activity at human RXFP3 expressed in CHOK1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP accumulation preincubated ...More data for this Ligand-Target Pair
Affinity DataEC50: 82nMAssay Description:Agonist activity at human RXFP3 expressed in CHOK1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP accumulation preincubated ...More data for this Ligand-Target Pair
Affinity DataEC50: 58nMAssay Description:Agonist activity at human RXFP4 expressed in CHOK1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP accumulation preincubated ...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataEC50: 50nMAssay Description:Binding affinity to human STING incubated for 60 mins measured by competitive TR-FRET assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataEC50: 700nMAssay Description:Binding affinity to human STING incubated for 60 mins measured by competitive TR-FRET assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataEC50: 1.31E+3nMAssay Description:Binding affinity to human STING incubated for 60 mins measured by competitive TR-FRET assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataEC50: 1.16E+4nMAssay Description:Binding affinity to human STING incubated for 60 mins measured by competitive TR-FRET assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataEC50: 8.45E+3nMAssay Description:Binding affinity to human STING incubated for 60 mins measured by competitive TR-FRET assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataEC50: 250nMAssay Description:Binding affinity to human STING incubated for 60 mins measured by competitive TR-FRET assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataEC50: 890nMAssay Description:Binding affinity to human STING incubated for 60 mins measured by competitive TR-FRET assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataEC50: 4.24E+4nMAssay Description:Binding affinity to human STING incubated for 60 mins measured by competitive TR-FRET assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataEC50: 4.20E+4nMAssay Description:Binding affinity to human STING incubated for 60 mins measured by competitive TR-FRET assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataEC50: 3.99E+4nMAssay Description:Binding affinity to human STING incubated for 60 mins measured by competitive TR-FRET assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataEC50: 85nMAssay Description:Binding affinity to human STING incubated for 60 mins measured by competitive TR-FRET assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataEC50: 102nMAssay Description:Binding affinity to human STING incubated for 60 mins measured by competitive TR-FRET assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataEC50: 80nMAssay Description:Binding affinity to human STING incubated for 60 mins measured by competitive TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetStimulator of interferon genes protein(Human)
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataEC50: 310nMAssay Description:Binding affinity to human STING incubated for 60 mins measured by competitive TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetStimulator of interferon genes protein(Human)
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataEC50: 1.03E+4nMAssay Description:Binding affinity to human STING incubated for 60 mins measured by competitive TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetStimulator of interferon genes protein(Human)
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataEC50: 172nMAssay Description:Binding affinity to human STING incubated for 60 mins measured by competitive TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetStimulator of interferon genes protein(Human)
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataEC50: 100nMAssay Description:Binding affinity to human STING incubated for 60 mins measured by competitive TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetStimulator of interferon genes protein(Human)
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataEC50: 150nMAssay Description:Binding affinity to human STING incubated for 60 mins measured by competitive TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetStimulator of interferon genes protein(Human)
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataEC50: 30nMAssay Description:Binding affinity to human STING incubated for 60 mins measured by competitive TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetStimulator of interferon genes protein(Human)
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataEC50: 3.10E+3nMAssay Description:Binding affinity to human STING incubated for 60 mins measured by competitive TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetStimulator of interferon genes protein(Human)
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataEC50: 1.91E+3nMAssay Description:Binding affinity to human STING incubated for 60 mins measured by competitive TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetStimulator of interferon genes protein(Human)
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataEC50: 1.91E+3nMAssay Description:Binding affinity to human STING incubated for 60 mins measured by competitive TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetStimulator of interferon genes protein(Human)
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at STING KO human THP-1 dual cells incubated for 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at STING KO human THP-1 dual cells incubated for 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at STING KO human THP-1 dual cells incubated for 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Mouse)
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataEC50: 7.16E+3nMAssay Description:Agonist activity at mouse STING in THP-1 dual cells incubated for 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Mouse)
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataEC50: 700nMAssay Description:Agonist activity at mouse STING in THP-1 dual cells incubated for 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Mouse)
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataEC50: 280nMAssay Description:Agonist activity at mouse STING in THP-1 dual cells incubated for 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Mouse)
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataEC50: 7.38E+3nMAssay Description:Agonist activity at STING in mouse RAW264.7 cells incubated for 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
