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TargetEpidermal growth factor receptor(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM31826(4-aminoquinazoline, 2a | BMC163482 Compound 3 | CH...)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of wild type EGFR by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetEpidermal growth factor receptor(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of wild type EGFR by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank
MMDB
PDB3D3D Structure (crystal)

TargetEpidermal growth factor receptor(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50314991(CHEMBL1089524 | N-(4-(3-Bromophenylamino)quinolin-...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of wild type EGFR by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50314992(CHEMBL1092382 | N-(4-(3-Bromophenylamino)quinolin-...)
Affinity DataIC50:  16nMAssay Description:Inhibition of wild type EGFR by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50314989(CHEMBL1092250 | N-(3-Ethynylphenyl)-6,7-dimethoxyq...)
Affinity DataIC50:  19nMAssay Description:Inhibition of wild type EGFR by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 9(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM13533(1-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-3...)
Affinity DataIC50:  27nMAssay Description:Displacemnt of N,N'-(2,2'-(3,3'-disulfanediylbis(2,5-dioxopyrrolidine-3,1-diyl))bis(ethane-2,1-diyl))bis(2-(3-(3-tert-butyl-5-(3-naphthalen-1-ylureid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetEpidermal growth factor receptor(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50314990(CHEMBL1089203 | N-(3-Ethynylphenyl)-6,7-bis(2-meth...)
Affinity DataIC50:  30nMAssay Description:Inhibition of wild type EGFR by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 14(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50303597((S)-2-(2-amino-3-phenylpropylamino)-3-methyl-5-(na...)
Affinity DataIC50:  35nMAssay Description:Inhibition of p38alpha active form expressed in Escherichia coli BL21(DE3) cells by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 14(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50266947(2-(6-chloro-5-((2R,5S)-4-(4-fluorobenzyl)-2,5-dime...)
Affinity DataIC50:  36nMAssay Description:Inhibition of p38alpha active form expressed in Escherichia coli BL21(DE3) cells by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetMitogen-activated protein kinase 14(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50303586(1-(3-tert-Butyl-1-(3-nitrophenyl)-1H-pyrazol-5-yl)...)
Affinity DataIC50:  45nMAssay Description:Displacemnt of N,N'-(2,2'-(3,3'-disulfanediylbis(2,5-dioxopyrrolidine-3,1-diyl))bis(ethane-2,1-diyl))bis(2-(3-(3-tert-butyl-5-(3-naphthalen-1-ylureid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 9(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM31825(1-(1-(3-Aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl)...)
Affinity DataIC50:  70nMAssay Description:Displacemnt of N,N'-(2,2'-(3,3'-disulfanediylbis(2,5-dioxopyrrolidine-3,1-diyl))bis(ethane-2,1-diyl))bis(2-(3-(3-tert-butyl-5-(3-naphthalen-1-ylureid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 14(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50303597((S)-2-(2-amino-3-phenylpropylamino)-3-methyl-5-(na...)
Affinity DataIC50:  75nMAssay Description:Displacemnt of N,N'-(2,2'-(3,3'-disulfanediylbis(2,5-dioxopyrrolidine-3,1-diyl))bis(ethane-2,1-diyl))bis(2-(3-(3-tert-butyl-5-(3-naphthalen-1-ylureid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 9(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50303597((S)-2-(2-amino-3-phenylpropylamino)-3-methyl-5-(na...)
Affinity DataIC50:  76nMAssay Description:Inhibition of JNK2 active form by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 14(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM31825(1-(1-(3-Aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl)...)
Affinity DataIC50:  90nMAssay Description:Inhibition of p38alpha active form expressed in Escherichia coli BL21(DE3) cells by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank
PDB3D3D Structure (crystal)

TargetMitogen-activated protein kinase 9(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM31825(1-(1-(3-Aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl)...)
Affinity DataIC50:  90nMAssay Description:Inhibition of JNK2 active form by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 14(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50303594(1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(3-(6...)
Affinity DataIC50:  95nMAssay Description:Displacemnt of N,N'-(2,2'-(3,3'-disulfanediylbis(2,5-dioxopyrrolidine-3,1-diyl))bis(ethane-2,1-diyl))bis(2-(3-(3-tert-butyl-5-(3-naphthalen-1-ylureid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB
PDB3D3D Structure (crystal)

TargetMitogen-activated protein kinase 14(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50266947(2-(6-chloro-5-((2R,5S)-4-(4-fluorobenzyl)-2,5-dime...)
Affinity DataIC50:  96nMAssay Description:Displacemnt of N,N'-(2,2'-(3,3'-disulfanediylbis(2,5-dioxopyrrolidine-3,1-diyl))bis(ethane-2,1-diyl))bis(2-(3-(3-tert-butyl-5-(3-naphthalen-1-ylureid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetMitogen-activated protein kinase 9(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50303591(1-(4-(6-aminoquinolin-4-ylamino)phenyl)-3-(3-tert-...)
Affinity DataIC50:  100nMAssay Description:Displacemnt of N,N'-(2,2'-(3,3'-disulfanediylbis(2,5-dioxopyrrolidine-3,1-diyl))bis(ethane-2,1-diyl))bis(2-(3-(3-tert-butyl-5-(3-naphthalen-1-ylureid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 14(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50303584(1-(3-tert-butyl-1-(3-nitrophenyl)-1H-pyrazol-5-yl)...)
Affinity DataIC50:  100nMAssay Description:Inhibition of p38alpha active form expressed in Escherichia coli BL21(DE3) cells by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 14(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM14832(3-(4-fluorophenyl)-2-pyridin-4-yl-6-thia-1,4-diaza...)
Affinity DataIC50:  110nMAssay Description:Inhibition of p38alpha active form expressed in Escherichia coli BL21(DE3) cells by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 14(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50303585(1-(3-tert-butyl-1-(3-nitrophenyl)-1H-pyrazol-5-yl)...)
Affinity DataIC50:  120nMAssay Description:Inhibition of p38alpha active form expressed in Escherichia coli BL21(DE3) cells by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 14(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50303596(CHEMBL566100 | N-(4-(3-(3-(3-tert-butyl-1-p-tolyl-...)
Affinity DataIC50:  140nMAssay Description:Inhibition of p38alpha active form expressed in Escherichia coli BL21(DE3) cells by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 14(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50303586(1-(3-tert-Butyl-1-(3-nitrophenyl)-1H-pyrazol-5-yl)...)
Affinity DataIC50:  150nMAssay Description:Inhibition of p38alpha active form expressed in Escherichia coli BL21(DE3) cells by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 14(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50303594(1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(3-(6...)
Affinity DataIC50:  150nMAssay Description:Inhibition of p38alpha active form expressed in Escherichia coli BL21(DE3) cells by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB
PDB3D3D Structure (crystal)

TargetMitogen-activated protein kinase 9(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM13533(1-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-3...)
Affinity DataIC50:  150nMAssay Description:Inhibition of JNK2 active form by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetMitogen-activated protein kinase 9(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM31831(quinazoline-pyrazolourea hybrid compound, 3e)
Affinity DataIC50:  150nMAssay Description:Inhibition of JNK2 active form by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 14(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM31825(1-(1-(3-Aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl)...)
Affinity DataIC50:  170nMAssay Description:Displacemnt of N,N'-(2,2'-(3,3'-disulfanediylbis(2,5-dioxopyrrolidine-3,1-diyl))bis(ethane-2,1-diyl))bis(2-(3-(3-tert-butyl-5-(3-naphthalen-1-ylureid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank
PDB3D3D Structure (crystal)

TargetMitogen-activated protein kinase 14(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM13533(1-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-3...)
Affinity DataIC50:  220nMAssay Description:Displacemnt of N,N'-(2,2'-(3,3'-disulfanediylbis(2,5-dioxopyrrolidine-3,1-diyl))bis(ethane-2,1-diyl))bis(2-(3-(3-tert-butyl-5-(3-naphthalen-1-ylureid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank
MMDB
PDB3D3D Structure (crystal)

TargetMitogen-activated protein kinase 14(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50303585(1-(3-tert-butyl-1-(3-nitrophenyl)-1H-pyrazol-5-yl)...)
Affinity DataIC50:  220nMAssay Description:Displacemnt of N,N'-(2,2'-(3,3'-disulfanediylbis(2,5-dioxopyrrolidine-3,1-diyl))bis(ethane-2,1-diyl))bis(2-(3-(3-tert-butyl-5-(3-naphthalen-1-ylureid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 14(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50303584(1-(3-tert-butyl-1-(3-nitrophenyl)-1H-pyrazol-5-yl)...)
Affinity DataIC50:  220nMAssay Description:Displacemnt of N,N'-(2,2'-(3,3'-disulfanediylbis(2,5-dioxopyrrolidine-3,1-diyl))bis(ethane-2,1-diyl))bis(2-(3-(3-tert-butyl-5-(3-naphthalen-1-ylureid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 9(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50303597((S)-2-(2-amino-3-phenylpropylamino)-3-methyl-5-(na...)
Affinity DataIC50:  220nMAssay Description:Displacemnt of N,N'-(2,2'-(3,3'-disulfanediylbis(2,5-dioxopyrrolidine-3,1-diyl))bis(ethane-2,1-diyl))bis(2-(3-(3-tert-butyl-5-(3-naphthalen-1-ylureid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 14(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50303595(1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(3-(q...)
Affinity DataIC50:  230nMAssay Description:Displacemnt of N,N'-(2,2'-(3,3'-disulfanediylbis(2,5-dioxopyrrolidine-3,1-diyl))bis(ethane-2,1-diyl))bis(2-(3-(3-tert-butyl-5-(3-naphthalen-1-ylureid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 14(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM13533(1-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-3...)
Affinity DataIC50:  250nMAssay Description:Inhibition of p38alpha active form expressed in Escherichia coli BL21(DE3) cells by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank
MMDB
PDB3D3D Structure (crystal)

TargetMitogen-activated protein kinase 14(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50303596(CHEMBL566100 | N-(4-(3-(3-(3-tert-butyl-1-p-tolyl-...)
Affinity DataIC50:  250nMAssay Description:Displacemnt of N,N'-(2,2'-(3,3'-disulfanediylbis(2,5-dioxopyrrolidine-3,1-diyl))bis(ethane-2,1-diyl))bis(2-(3-(3-tert-butyl-5-(3-naphthalen-1-ylureid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 14(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50303593(1-(3-(6-aminoquinolin-4-ylamino)phenyl)-3-(3-tert-...)
Affinity DataIC50:  290nMAssay Description:Inhibition of p38alpha active form expressed in Escherichia coli BL21(DE3) cells by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB
PDB3D3D Structure (crystal)

TargetMitogen-activated protein kinase 14(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50303595(1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(3-(q...)
Affinity DataIC50:  290nMAssay Description:Inhibition of p38alpha active form expressed in Escherichia coli BL21(DE3) cells by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 14(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50303593(1-(3-(6-aminoquinolin-4-ylamino)phenyl)-3-(3-tert-...)
Affinity DataIC50:  310nMAssay Description:Displacemnt of N,N'-(2,2'-(3,3'-disulfanediylbis(2,5-dioxopyrrolidine-3,1-diyl))bis(ethane-2,1-diyl))bis(2-(3-(3-tert-butyl-5-(3-naphthalen-1-ylureid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB
PDB3D3D Structure (crystal)

TargetMitogen-activated protein kinase 14(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM31831(quinazoline-pyrazolourea hybrid compound, 3e)
Affinity DataIC50:  320nMAssay Description:Inhibition of p38alpha active form expressed in Escherichia coli BL21(DE3) cells by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB
PDB3D3D Structure (crystal)

TargetMitogen-activated protein kinase 14(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50303590(1-(3-(6-aminoquinazolin-4-ylamino)phenyl)-3-(3-ter...)
Affinity DataIC50:  370nMAssay Description:Displacemnt of N,N'-(2,2'-(3,3'-disulfanediylbis(2,5-dioxopyrrolidine-3,1-diyl))bis(ethane-2,1-diyl))bis(2-(3-(3-tert-butyl-5-(3-naphthalen-1-ylureid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB
PDB3D3D Structure (crystal)

TargetMitogen-activated protein kinase 9(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50303591(1-(4-(6-aminoquinolin-4-ylamino)phenyl)-3-(3-tert-...)
Affinity DataIC50:  380nMAssay Description:Inhibition of JNK2 active form by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 14(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Affinity DataIC50:  400nMAssay Description:Displacemnt of N,N'-(2,2'-(3,3'-disulfanediylbis(2,5-dioxopyrrolidine-3,1-diyl))bis(ethane-2,1-diyl))bis(2-(3-(3-tert-butyl-5-(3-naphthalen-1-ylureid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB
PDB3D3D Structure (crystal)

TargetMitogen-activated protein kinase 14(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM31831(quinazoline-pyrazolourea hybrid compound, 3e)
Affinity DataIC50:  420nMAssay Description:Displacemnt of N,N'-(2,2'-(3,3'-disulfanediylbis(2,5-dioxopyrrolidine-3,1-diyl))bis(ethane-2,1-diyl))bis(2-(3-(3-tert-butyl-5-(3-naphthalen-1-ylureid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB
PDB3D3D Structure (crystal)

TargetMitogen-activated protein kinase 14(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50303592(CHEMBL568756 | N-(4-(4-(3-(3-tert-butyl-1-m-tolyl-...)
Affinity DataIC50:  420nMAssay Description:Displacemnt of N,N'-(2,2'-(3,3'-disulfanediylbis(2,5-dioxopyrrolidine-3,1-diyl))bis(ethane-2,1-diyl))bis(2-(3-(3-tert-butyl-5-(3-naphthalen-1-ylureid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 14(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50115216(1-(1-(3-Aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl)...)
Affinity DataIC50:  440nMAssay Description:Displacemnt of N,N'-(2,2'-(3,3'-disulfanediylbis(2,5-dioxopyrrolidine-3,1-diyl))bis(ethane-2,1-diyl))bis(2-(3-(3-tert-butyl-5-(3-naphthalen-1-ylureid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 9(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50303587(1-(3-tert-butyl-1-m-tolyl-1H-pyrazol-5-yl)-3-(4-ch...)
Affinity DataIC50:  440nMAssay Description:Displacemnt of N,N'-(2,2'-(3,3'-disulfanediylbis(2,5-dioxopyrrolidine-3,1-diyl))bis(ethane-2,1-diyl))bis(2-(3-(3-tert-butyl-5-(3-naphthalen-1-ylureid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 14(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50303590(1-(3-(6-aminoquinazolin-4-ylamino)phenyl)-3-(3-ter...)
Affinity DataIC50:  460nMAssay Description:Inhibition of p38alpha active form expressed in Escherichia coli BL21(DE3) cells by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB
PDB3D3D Structure (crystal)

TargetMitogen-activated protein kinase 14(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50303591(1-(4-(6-aminoquinolin-4-ylamino)phenyl)-3-(3-tert-...)
Affinity DataIC50:  470nMAssay Description:Displacemnt of N,N'-(2,2'-(3,3'-disulfanediylbis(2,5-dioxopyrrolidine-3,1-diyl))bis(ethane-2,1-diyl))bis(2-(3-(3-tert-butyl-5-(3-naphthalen-1-ylureid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB
PDB3D3D Structure (crystal)

TargetMitogen-activated protein kinase 9(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM31828(quinazoline-pyrazolourea hybrid compound, 3b)
Affinity DataIC50:  570nMAssay Description:Inhibition of JNK2 active form by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 14(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50303588(1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-p-tol...)
Affinity DataIC50:  680nMAssay Description:Displacemnt of N,N'-(2,2'-(3,3'-disulfanediylbis(2,5-dioxopyrrolidine-3,1-diyl))bis(ethane-2,1-diyl))bis(2-(3-(3-tert-butyl-5-(3-naphthalen-1-ylureid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 14(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM31827(quinazoline-pyrazolourea hybrid compound, 3a)
Affinity DataIC50:  760nMAssay Description:Displacemnt of N,N'-(2,2'-(3,3'-disulfanediylbis(2,5-dioxopyrrolidine-3,1-diyl))bis(ethane-2,1-diyl))bis(2-(3-(3-tert-butyl-5-(3-naphthalen-1-ylureid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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