Report error Found 162 with Last Name = 'perrakis' and Initial = 'a'
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataEC50: 100nMAssay Description:Inhibition of LPA-mediated ATX activation in human BJeH cells assessed as AKT phosphorylation level incubated for 30 mins by Western blot analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataEC50: 60nMAssay Description:Inhibition of LPA-mediated ATX activation in human BJeH cells assessed as AKT phosphorylation level incubated for 30 mins by Western blot analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataEC50: 100nMAssay Description:Inhibition of LPA-mediated ATX activation in human BJeH cells assessed as ERK phosphorylation level incubated for 30 mins by Western blot analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataEC50: 60nMAssay Description:Inhibition of LPA-mediated ATX activation in human BJeH cells assessed as ERK phosphorylation level incubated for 30 mins by Western blot analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataEC50: 186nMAssay Description:Inhibition of LPA-mediated ATX activation in human MDA-MB-231 cells assessed as reduction in cell migration incubated for 4 hrs in using18:1 LPC as s...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of ATX (unknown origin) using lysophosphatidyl choline as substrateMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human ATX expressed in HEK293 cells using FS-3 as substrate preincubated for 15 mins followed by substrate addition measured after 30 m...More data for this Ligand-Target Pair
3D Structure (crystal)TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human ATX expressed in HEK293 cells using FS-3 as substrate after 15 minsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant human ATX using bisP-nitrophenyl phosphate as substrate measured after 30 minsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human ATX using bisP-nitrophenyl phosphate as substrate measured after 30 minsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataIC50: 5.30nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells assessed as choline release using lysophosphatidylcholine as substr...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataIC50: 5.70nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells assessed as choline release using lysophosphatidylcholine as substr...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataIC50: 6.70nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells assessed as choline release using lysophosphatidylcholine as substr...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataIC50: 7.30nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells assessed as choline release using lysophosphatidylcholine as substr...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataIC50: 8.30nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells assessed as choline release using lysophosphatidylcholine as substr...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells assessed as choline release using lysophosphatidylcholine as substr...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of human ATX expressed in HEK293 Flp-In cells using LPC as substrate measured every 30 sec for 90 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of human ATX expressed in HEK293 Flp-In cells assessed as decrease in choline release from LPC measured every 30 secs for 90 mins by HVA b...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of rat ATX lysoPLD activity using LPC as substrate assessed as reduction in choline release measured after 60 mins by HVA fluorescence bas...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant HA-tagged ATX (unknown origin) using FS-3 as substrate measured after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant human ATX using bisP-nitrophenyl phosphate as substrate measured after 30 minsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells assessed as choline release using lysophosphatidylcholine as substr...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of human ATX expressed in HEK293 Flp-In cells using LPC as substrate measured every 30 sec for 90 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of human ATX expressed in HEK293 Flp-In cells using LPC as substrate measured every 30 sec for 90 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells assessed as choline release using lysophosphatidylcholine as substr...More data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibition of rat ATX lysoPLD activity assessed as reduction in choline release using 18:1 LPC as substrate measured after 60 mins by HVA fluorescenc...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of rat ATX lysoPLD activity using LPC as substrate assessed as reduction in choline release measured after 60 mins by HVA fluorescence bas...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of human ATX expressed in HEK293 Flp-In cells using LPC as substrate measured every 30 sec for 90 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of rat ATX lysoPLD activity assessed as reduction in choline release using 20:0 LPC as substrate measured after 60 mins by HVA fluorescenc...More data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Inhibition of rat ATX lysoPLD activity assessed as reduction in choline release using 20:0 LPC as substrate measured after 60 mins by HVA fluorescenc...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibition of recombinant human ATX using bisP-nitrophenyl phosphate as substrate measured after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibition of rat ATX lysoPLD activity assessed as reduction in choline release using 16:0 LPC as substrate measured after 60 mins by HVA fluorescenc...More data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Inhibition of rat ATX lysoPLD activity assessed as reduction in choline release using 18:1 LPC as substrate measured after 60 mins by HVA fluorescenc...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of rat ATX lysoPLD activity using LPC as substrate assessed as reduction in choline release measured after 60 mins by HVA fluorescence bas...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of rat ATX lysoPLD activity using LPC as substrate assessed as reduction in choline release measured after 60 mins by HVA fluorescence bas...More data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Inhibition of rat ATX lysoPLD activity assessed as reduction in choline release using 14:0 LPC as substrate measured after 60 mins by HVA fluorescenc...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells assessed as choline release using lysophosphatidylcholine as substr...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataIC50: 59nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells assessed as choline release using lysophosphatidylcholine as substr...More data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of rat ATX lysoPLD activity using LPC as substrate assessed as reduction in choline release measured after 60 mins by HVA fluorescence bas...More data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of rat ATX lysoPLD activity using LPC as substrate assessed as reduction in choline release measured after 60 mins by HVA fluorescence bas...More data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of rat ATX lysoPLD activity using LPC as substrate assessed as reduction in choline release measured after 60 mins by HVA fluorescence bas...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataIC50: 71nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells assessed as choline release using lysophosphatidylcholine as substr...More data for this Ligand-Target Pair
Affinity DataIC50: 72nMAssay Description:Inhibition of rat ATX lysoPLD activity assessed as reduction in choline release using 16:0 LPC as substrate measured after 60 mins by HVA fluorescenc...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataIC50: 75nMAssay Description:Inhibition of recombinant human ATX using bisP-nitrophenyl phosphate as substrate measured after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of rat ATX lysoPLD activity using LPC as substrate assessed as reduction in choline release measured after 60 mins by HVA fluorescence bas...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataIC50: 81nMAssay Description:Inhibition of human ATX expressed in HEK293 Flp-In cells using LPC as substrate measured every 30 sec for 90 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 84nMAssay Description:Inhibition of rat ATX lysoPLD activity assessed as reduction in choline release using 14:0 LPC as substrate measured after 60 mins by HVA fluorescenc...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataIC50: 85nMAssay Description:Inhibition of recombinant human ATX using bisP-nitrophenyl phosphate as substrate measured after 30 minsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataIC50: 89nMAssay Description:Inhibition of recombinant human ATX using bisP-nitrophenyl phosphate as substrate measured after 30 minsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of human ATX expressed in HEK293 Flp-In cells assessed as decrease in choline release from LPC measured every 30 secs for 90 mins by HVA b...More data for this Ligand-Target Pair
