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TargetEstrogen receptor beta(Human)
Inserm Unit�

Curated by ChEMBL
LigandPNGBDBM50471261(CHEMBL1627868)
Affinity DataEC50: <10nMAssay Description:Compound concentration required to induce transcriptional activation in MVLN cells comparable to 50% of 0.1 nM estradiol responseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEstrogen receptor beta(Human)
Inserm Unit�

Curated by ChEMBL
LigandPNGBDBM50471263(CHEMBL1627873)
Affinity DataEC50:  6nMAssay Description:Compound concentration required to induce transcriptional activation in MVLN cells comparable to 50% of 0.1 nM estradiol responseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEstrogen receptor beta(Human)
Inserm Unit�

Curated by ChEMBL
LigandPNGBDBM50471265(CHEMBL1627460)
Affinity DataEC50:  110nMAssay Description:Compound concentration required to induce transcriptional activation in MVLN cells comparable to 50% of 0.1 nM estradiol responseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50556952(CHEMBL4754487)
Affinity DataKd:  0.940nMAssay Description:Mixed-type inhibition of recombinant human AChE using varying concentration of acetylthiocholine iodide as substrate at 0.17 to 1.36 nM by Lineweaver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50556952(CHEMBL4754487)
Affinity DataKd:  3.60nMAssay Description:Displacement of propidium iodide from PAS-region of electric eel AChE assessed as dissociation constant by spectrofluorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50556952(CHEMBL4754487)
Affinity DataIC50: 0.770nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50556958(CHEMBL4744528)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM10592(7-chloro-15-methyl-10-azatetracyclo[11.3.1.0^{2,11...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50556953(CHEMBL4748114)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50556954(CHEMBL4782921)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEstrogen receptor beta(Human)
Inserm Unit�

Curated by ChEMBL
LigandPNGBDBM50471264(CHEMBL1627893)
Affinity DataIC50: 3nMAssay Description:Compound concentration required to induce transcriptional activation in MVLN cells equal to 50% of 0.1 nM estradiol responseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEstrogen receptor beta(Human)
Inserm Unit�

Curated by ChEMBL
LigandPNGBDBM50276802(4-OHT | Afimoxifene | TamoGel)
Affinity DataIC50: 3nMAssay Description:Anti-estrogenicity for 50% inhibition of the MVLN cell luciferase activity due to 0.1 nM E2 (estradiol)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEstrogen receptor beta(Human)
Inserm Unit�

Curated by ChEMBL
LigandPNGBDBM50471259(CHEMBL1627458)
Affinity DataIC50: 4nMAssay Description:Compound concentration required to induce transcriptional activation in MVLN cells equal to 50% of 0.1 nM estradiol responseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50556951(CHEMBL4788434)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50556956(CHEMBL4741162)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50556950(CHEMBL4743210)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50556957(CHEMBL4794769)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEstrogen receptor beta(Human)
Inserm Unit�

Curated by ChEMBL
LigandPNGBDBM50471260(CHEMBL1628165)
Affinity DataIC50: 6nMAssay Description:Compound concentration required to induce transcriptional activation in MVLN cells equal to 50% of 0.1 nM estradiol responseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEstrogen receptor beta(Human)
Inserm Unit�

Curated by ChEMBL
LigandPNGBDBM50471266(CHEMBL303196)
Affinity DataIC50: 7nMAssay Description:Compound concentration required to induce transcriptional activation in MVLN cells equal to 50% of 0.1 nM estradiol responseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50556958(CHEMBL4744528)
Affinity DataIC50: 7.30nMAssay Description:Inhibition of human serum BChE using butyrylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50556955(CHEMBL4782267)
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50556952(CHEMBL4754487)
Affinity DataIC50: 31nMAssay Description:Inhibition of human serum BChE using butyrylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50556954(CHEMBL4782921)
Affinity DataIC50: 36nMAssay Description:Inhibition of human serum BChE using butyrylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50556950(CHEMBL4743210)
Affinity DataIC50: 52nMAssay Description:Inhibition of human serum BChE using butyrylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50556953(CHEMBL4748114)
Affinity DataIC50: 52nMAssay Description:Inhibition of human serum BChE using butyrylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50556957(CHEMBL4794769)
Affinity DataIC50: 53nMAssay Description:Inhibition of human serum BChE using butyrylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50556951(CHEMBL4788434)
Affinity DataIC50: 70nMAssay Description:Inhibition of human serum BChE using butyrylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50556956(CHEMBL4741162)
Affinity DataIC50: 78nMAssay Description:Inhibition of human serum BChE using butyrylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEstrogen receptor beta(Human)
Inserm Unit�

Curated by ChEMBL
LigandPNGBDBM50471588(CHEMBL1237293)
Affinity DataIC50: 150nMAssay Description:Anti-estrogenicity for 50% inhibition of the MVLN cell luciferase activity due to 0.1 nM E2 (estradiol)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM10592(7-chloro-15-methyl-10-azatetracyclo[11.3.1.0^{2,11...)
Affinity DataIC50: 181nMAssay Description:Inhibition of human serum BChE using butyrylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEstrogen receptor beta(Human)
Inserm Unit�

Curated by ChEMBL
LigandPNGBDBM50471604(CHEMBL273663)
Affinity DataIC50: 200nMAssay Description:Anti-estrogenicity for 50% inhibition of the MVLN cell luciferase activity due to 0.1 nM E2 (estradiol)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50556955(CHEMBL4782267)
Affinity DataIC50: 290nMAssay Description:Inhibition of human serum BChE using butyrylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEstrogen receptor beta(Human)
Inserm Unit�

Curated by ChEMBL
LigandPNGBDBM20607((2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethy...)
Affinity DataIC50: 300nMAssay Description:Anti-estrogenicity for 50% inhibition of the MVLN cell luciferase activity due to 0.1 nM E2 (estradiol)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEstrogen receptor beta(Human)
Inserm Unit�

Curated by ChEMBL
LigandPNGBDBM50471262(CHEMBL1628147)
Affinity DataIC50: 320nMAssay Description:Compound concentration required to induce transcriptional activation in MVLN cells equal to 50% of 0.1 nM estradiol responseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50459230(CHEMBL4215472)
Affinity DataIC50: 400nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv His-tagged ptpB expressed in Escherichia coli BL21(DE3) using pNPP as substrate preincubated for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEstrogen receptor beta(Human)
Inserm Unit�

Curated by ChEMBL
LigandPNGBDBM50471587(CHEMBL13289)
Affinity DataIC50: 500nMAssay Description:Anti-estrogenicity for 50% inhibition of the MVLN cell luciferase activity due to 0.1 nM E2 (estradiol)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEstrogen receptor beta(Human)
Inserm Unit�

Curated by ChEMBL
LigandPNGBDBM50471592(CHEMBL12959)
Affinity DataIC50: 500nMAssay Description:Anti-estrogenicity for 50% inhibition of the MVLN cell luciferase activity due to 0.1 nM E2 (estradiol)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50459230(CHEMBL4215472)
Affinity DataIC50: 780nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv His-tagged ptpB R136A mutant expressed in Escherichia coli BL21(DE3) using pNPP as substrate preincuba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50459225(CHEMBL4211060)
Affinity DataIC50: 900nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv His-tagged ptpB expressed in Escherichia coli BL21(DE3) using pNPP as substrate preincubated for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEstrogen receptor beta(Human)
Inserm Unit�

Curated by ChEMBL
LigandPNGBDBM50471598(CHEMBL13489)
Affinity DataIC50: 900nMAssay Description:Anti-estrogenicity for 50% inhibition of the MVLN cell luciferase activity due to 0.1 nM E2 (estradiol)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50459227(CHEMBL4217308)
Affinity DataIC50: 920nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv His-tagged ptpB expressed in Escherichia coli BL21(DE3) using pNPP as substrate preincubated for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50459227(CHEMBL4217308)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv His-tagged ptpB R136A mutant expressed in Escherichia coli BL21(DE3) using pNPP as substrate preincuba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50459230(CHEMBL4215472)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv His-tagged ptpB H94A mutant expressed in Escherichia coli BL21(DE3) using pNPP as substrate preincubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50459232(CHEMBL4206173)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv His-tagged ptpB expressed in Escherichia coli BL21(DE3) using pNPP as substrate preincubated for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50459233(CHEMBL4207543)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv His-tagged ptpB expressed in Escherichia coli BL21(DE3) using pNPP as substrate preincubated for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50459227(CHEMBL4217308)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv His-tagged ptpB H94A mutant expressed in Escherichia coli BL21(DE3) using pNPP as substrate preincubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEstrogen receptor beta(Human)
Inserm Unit�

Curated by ChEMBL
LigandPNGBDBM50471605(CHEMBL13251)
Affinity DataIC50: 1.30E+3nMAssay Description:Anti-estrogenicity for 50% inhibition of the MVLN cell luciferase activity due to 0.1 nM E2 (estradiol)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50459226(CHEMBL4210532)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv His-tagged ptpB expressed in Escherichia coli BL21(DE3) using pNPP as substrate preincubated for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEstrogen receptor beta(Human)
Inserm Unit�

Curated by ChEMBL
LigandPNGBDBM50471593(CHEMBL269227)
Affinity DataIC50: 1.50E+3nMAssay Description:Anti-estrogenicity for 50% inhibition of the MVLN cell luciferase activity due to 0.1 nM E2 (estradiol)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEstrogen receptor beta(Human)
Inserm Unit�

Curated by ChEMBL
LigandPNGBDBM50471600(CHEMBL12865)
Affinity DataIC50: 1.50E+3nMAssay Description:Anti-estrogenicity for 50% inhibition of the MVLN cell luciferase activity due to 0.1 nM E2 (estradiol)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
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