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TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50243592(1-(4-methoxyphenyl)-6-(4-(1-(pyrrolidin-1-ylmethyl...)
Affinity DataKi:  0.0200nMAssay Description:Binding affinity to human coagulation factor 10aMore data for this Ligand-Target Pair
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50266214(6-(4-(1-(2-(dimethylamino)ethyl)cyclopropyl)phenyl...)
Affinity DataKi:  0.0200nMAssay Description:Binding affinity to human coagulation factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50266249(6-(4-(1-(4,5-dihydro-1H-imidazol-2-yl)cyclopropyl)...)
Affinity DataKi:  0.0200nMAssay Description:Binding affinity to human coagulation factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50266215(1-(4-methoxyphenyl)-6-(4-(1-(2-(pyrrolidin-1-yl)et...)
Affinity DataKi:  0.0200nMAssay Description:Binding affinity to human coagulation factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50243592(1-(4-methoxyphenyl)-6-(4-(1-(pyrrolidin-1-ylmethyl...)
Affinity DataKi:  0.0210nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50243668(1-(4-methoxyphenyl)-6-(4-(1-((2-methyl-1H-imidazol...)
Affinity DataKi:  0.0250nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50243668(1-(4-methoxyphenyl)-6-(4-(1-((2-methyl-1H-imidazol...)
Affinity DataKi:  0.0250nMAssay Description:Binding affinity to human coagulation factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50266047(1-(4-methoxyphenyl)-7-oxo-6-(4-(1-(pyrrolidin-1-yl...)
Affinity DataKi:  0.0270nMAssay Description:Binding affinity to human coagulation factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50243540(6-(4-(1-((dimethylamino)methyl)cyclopropyl)phenyl)...)
Affinity DataKi:  0.0350nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50243540(6-(4-(1-((dimethylamino)methyl)cyclopropyl)phenyl)...)
Affinity DataKi:  0.0350nMAssay Description:Binding affinity to human coagulation factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50243340((R)-6-(4-(1-((3-hydroxypyrrolidin-1-yl)methyl)cycl...)
Affinity DataKi:  0.0380nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50266010(6-(4-(1-((dimethylamino)methyl)cyclopropyl)phenyl)...)
Affinity DataKi:  0.0400nMAssay Description:Binding affinity to human coagulation factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50266049(1-(4-methoxyphenyl)-6-(4-(1-(morpholinomethyl)cycl...)
Affinity DataKi:  0.0400nMAssay Description:Binding affinity to human coagulation factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265826(6-(4-(1-(dimethylamino)cyclopropyl)phenyl)-1-(4-me...)
Affinity DataKi:  0.0400nMAssay Description:Binding affinity to human coagulation factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50243590(6-(4-(1-((isopropylamino)methyl)cyclopropyl)phenyl...)
Affinity DataKi:  0.0420nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50266012(1-(4-methoxyphenyl)-3-(methylsulfonyl)-6-(4-(1-(py...)
Affinity DataKi:  0.0500nMAssay Description:Binding affinity to human coagulation factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50046440(CHEMBL3314447)
Affinity DataKi:  0.0500nMAssay Description:Inhibition of purified human factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50046438(CHEMBL3359592)
Affinity DataKi:  0.0500nMAssay Description:Inhibition of purified human factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50266009(6-(4-(1-((dimethylamino)methyl)cyclopropyl)phenyl)...)
Affinity DataKi:  0.0500nMAssay Description:Binding affinity to human coagulation factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50266011(6-(4-(1-((dimethylamino)methyl)cyclopropyl)phenyl)...)
Affinity DataKi:  0.0500nMAssay Description:Binding affinity to human coagulation factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50243630(1-(4-methoxyphenyl)-6-(4-(1-((thiazol-2-ylamino)me...)
Affinity DataKi:  0.0540nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50243669(CHEMBL511486 | N-((1-(4-(1-(4-methoxyphenyl)-7-oxo...)
Affinity DataKi:  0.0550nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265977(1-(4-methoxyphenyl)-6-(4-(1-((methylamino)methyl)c...)
Affinity DataKi:  0.0600nMAssay Description:Binding affinity to human coagulation factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50243628(1-(4-methoxyphenyl)-6-(4-(1-(morpholinomethyl)cycl...)
Affinity DataKi:  0.0600nMAssay Description:Binding affinity to human coagulation factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50046441(CHEMBL3314448)
Affinity DataKi:  0.0600nMAssay Description:Inhibition of purified human factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50243628(1-(4-methoxyphenyl)-6-(4-(1-(morpholinomethyl)cycl...)
Affinity DataKi:  0.0640nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50046434(CHEMBL3314445)
Affinity DataKi:  0.0700nMAssay Description:Inhibition of purified human factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50046521(CHEMBL3314454)
Affinity DataKi:  0.0700nMAssay Description:Inhibition of purified human factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50266080(1-(4-methoxyphenyl)-6-(4-(1-((2-methyl-1H-imidazol...)
Affinity DataKi:  0.0700nMAssay Description:Binding affinity to human coagulation factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50266320(1-(4-methoxyphenyl)-6-(4-(1-(methylamino)cycloprop...)
Affinity DataKi:  0.0700nMAssay Description:Binding affinity to human coagulation factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265916(1-(4-methoxyphenyl)-6-(4-(1-(methylsulfonylmethyl)...)
Affinity DataKi:  0.0700nMAssay Description:Binding affinity to human coagulation factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265948(6-(4-(1-((2-hydroxyethyl)(methyl)amino)cyclopropyl...)
Affinity DataKi:  0.0700nMAssay Description:Binding affinity to human coagulation factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50266013(1-(4-methoxyphenyl)-7-oxo-6-(4-(1-(pyrrolidin-1-yl...)
Affinity DataKi:  0.0700nMAssay Description:Binding affinity to human coagulation factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50243670(CHEMBL471734 | N-((1-(4-(1-(4-methoxyphenyl)-7-oxo...)
Affinity DataKi:  0.0740nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM19023(1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-y...)
Affinity DataKi:  0.0800nMAssay Description:Inhibition of purified human factor XaMore data for this Ligand-Target Pair
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM19023(1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-y...)
Affinity DataKi:  0.0800nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM19023(1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-y...)
Affinity DataKi:  0.0800nMAssay Description:Binding affinity to human coagulation factor 10aMore data for this Ligand-Target Pair
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265827(6-(4-(1-(dimethylamino)cyclopropyl)phenyl)-1-(4-me...)
Affinity DataKi:  0.0800nMAssay Description:Binding affinity to human coagulation factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50266048(1-(4-methoxyphenyl)-3-(methylsulfonyl)-6-(4-(1-(mo...)
Affinity DataKi:  0.0800nMAssay Description:Binding affinity to human coagulation factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50266112(6-(4-(1-(dimethylamino)cyclopropyl)phenyl)-1-(4-me...)
Affinity DataKi:  0.0900nMAssay Description:Binding affinity to human coagulation factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50266050(1-(4-methoxyphenyl)-6-(4-(1-(morpholinomethyl)cycl...)
Affinity DataKi:  0.0900nMAssay Description:Binding affinity to human coagulation factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50046430(CHEMBL3314442)
Affinity DataKi:  0.110nMAssay Description:Inhibition of purified human factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50266082(1-(4-methoxyphenyl)-7-oxo-6-(4-(1-((2-oxopyrrolidi...)
Affinity DataKi:  0.110nMAssay Description:Binding affinity to human coagulation factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Pharmaron Beijing

Curated by ChEMBL
LigandPNGBDBM50604026(CHEMBL5192384)
Affinity DataKi:  0.110nMAssay Description:Displacement of [3H] labeled-N-(4-Fluorophenyl)-3-(4-(4-(2-hydroxypropan-2-yl)-6-(trifluoromethyl)pyridin-3-yl)phenyl)oxetane-3-carboxamide from huma...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50243591(6-(4-(1-((cyclopentylamino)methyl)cyclopropyl)phen...)
Affinity DataKi:  0.120nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50266113(6-(4-(1-((2-hydroxyethyl)(methyl)amino)cyclopropyl...)
Affinity DataKi:  0.120nMAssay Description:Binding affinity to human coagulation factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrotensin-2 receptor(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50302273((4R,7S,10S,13S,16S,19R)-13-((1H-indol-3-yl)methyl)...)
Affinity DataKi:  0.120nMAssay Description:Displacement of [125I]urotensin 2 from rat urotensin 2 receptor expressed in CHOK1 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50243629(6-(4-(1-((4-hydroxypiperidin-1-yl)methyl)cycloprop...)
Affinity DataKi:  0.140nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50242831(3-ethyl-1-((1-(4-(1-(4-methoxyphenyl)-7-oxo-3-(tri...)
Affinity DataKi:  0.140nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265828(1-(4-methoxyphenyl)-6-(4-(1-(2-morpholinoethyl)cyc...)
Affinity DataKi:  0.140nMAssay Description:Binding affinity to human coagulation factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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