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TargetHydroxycarboxylic acid receptor 2(Human)
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM23515(pyridine-3-carboxylic acid | CHEMBL573 | [5, 6-3H]...)
Affinity DataEC50:  2.75E+3nMAssay Description:Agonist activity at human GPR109a expressed in HTLA cells assessed as increase in beta-arrestin2 recruitment after overnight incubation by Tango assa...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetHydroxycarboxylic acid receptor 2(Human)
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50405697(CHEMBL4164140)
Affinity DataEC50:  11nMAssay Description:Agonist activity at human GPR109a expressed in HEK293 cells harboring glosensor-22F cAMP plasmid DNA assessed as inhibition of forskolin-stimulated c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50405698(CHEMBL4159670)
Affinity DataEC50:  457nMAssay Description:Agonist activity at human GPR109a expressed in HTLA cells assessed as increase in beta-arrestin2 recruitment after overnight incubation by Tango assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50405699(CHEMBL4174798)
Affinity DataEC50:  232nMAssay Description:Agonist activity at human GPR109a expressed in HTLA cells assessed as increase in beta-arrestin2 recruitment after overnight incubation by Tango assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM23515(pyridine-3-carboxylic acid | CHEMBL573 | [5, 6-3H]...)
Affinity DataEC50:  2.73E+3nMAssay Description:Agonist activity at human GPR109a expressed in HTLA cells assessed as increase in beta-arrestin2 recruitment after overnight incubation by Tango assa...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetHydroxycarboxylic acid receptor 2(Human)
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50405697(CHEMBL4164140)
Affinity DataEC50:  11nMAssay Description:Agonist activity at human GPR109a expressed in HEK293 cells harboring glosensor-22F cAMP plasmid DNA assessed as inhibition of forskolin-stimulated c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50405699(CHEMBL4174798)
Affinity DataEC50:  30nMAssay Description:Agonist activity at human GPR109a expressed in HEK293 cells harboring glosensor-22F cAMP plasmid DNA assessed as inhibition of forskolin-stimulated c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM23515(pyridine-3-carboxylic acid | CHEMBL573 | [5, 6-3H]...)
Affinity DataEC50:  21nMAssay Description:Agonist activity at human GPR109a expressed in HEK293 cells harboring glosensor-22F cAMP plasmid DNA assessed as inhibition of forskolin-stimulated c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetHydroxycarboxylic acid receptor 2(Human)
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50405698(CHEMBL4159670)
Affinity DataEC50:  454nMAssay Description:Agonist activity at human GPR109a expressed in HTLA cells assessed as increase in beta-arrestin2 recruitment after overnight incubation by Tango assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50405697(CHEMBL4164140)
Affinity DataEC50:  1.69E+3nMAssay Description:Agonist activity at human GPR109a expressed in HTLA cells assessed as increase in beta-arrestin2 recruitment after overnight incubation by Tango assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50405699(CHEMBL4174798)
Affinity DataEC50:  31nMAssay Description:Agonist activity at human GPR109a expressed in HEK293 cells harboring glosensor-22F cAMP plasmid DNA assessed as inhibition of forskolin-stimulated c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50405700(CHEMBL4163051)
Affinity DataEC50:  275nMAssay Description:Agonist activity at human GPR109a expressed in HTLA cells assessed as increase in beta-arrestin2 recruitment after overnight incubation by Tango assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50405701(CHEMBL4167588)
Affinity DataEC50:  1.02E+3nMAssay Description:Agonist activity at human GPR109a expressed in HTLA cells assessed as increase in beta-arrestin2 recruitment after overnight incubation by Tango assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50405697(CHEMBL4164140)
Affinity DataEC50:  1.70E+3nMAssay Description:Agonist activity at human GPR109a expressed in HTLA cells assessed as increase in beta-arrestin2 recruitment after overnight incubation by Tango assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50405699(CHEMBL4174798)
Affinity DataEC50:  234nMAssay Description:Agonist activity at human GPR109a expressed in HTLA cells assessed as increase in beta-arrestin2 recruitment after overnight incubation by Tango assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50405700(CHEMBL4163051)
Affinity DataEC50:  276nMAssay Description:Agonist activity at human GPR109a expressed in HTLA cells assessed as increase in beta-arrestin2 recruitment after overnight incubation by Tango assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50405701(CHEMBL4167588)
Affinity DataEC50:  1.01E+3nMAssay Description:Agonist activity at human GPR109a expressed in HTLA cells assessed as increase in beta-arrestin2 recruitment after overnight incubation by Tango assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM23515(pyridine-3-carboxylic acid | CHEMBL573 | [5, 6-3H]...)
Affinity DataEC50:  21nMAssay Description:Agonist activity at human GPR109a expressed in HEK293 cells harboring glosensor-22F cAMP plasmid DNA assessed as inhibition of forskolin-stimulated c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetD(2) dopamine receptor(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50463981(CHEMBL4242192)
Affinity DataEC50:  3nMAssay Description:Agonist activity at human dopamine D2 receptor expressed in HEK293T cells assessed as reduction in forskolin-induced cAMP accumulation preincubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50463984(CHEMBL4241844)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at human dopamine D2 receptor /mGluR5a (unknown origin) expressed in HEK293T cells assessed as reduction in forskolin-induced cAMP a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50463984(CHEMBL4241844)
Affinity DataEC50:  3.30nMAssay Description:Agonist activity at human dopamine D2 receptor expressed in HEK293T cells assessed as reduction in forskolin-induced cAMP accumulation preincubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50463986(CHEMBL4246185)
Affinity DataEC50:  5.5nMAssay Description:Agonist activity at human dopamine D2 receptor expressed in HEK293T cells assessed as reduction in forskolin-induced cAMP accumulation preincubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50463981(CHEMBL4242192)
Affinity DataEC50:  6.5nMAssay Description:Agonist activity at human dopamine D2 receptor /mGluR5a (unknown origin) expressed in HEK293T cells assessed as reduction in forskolin-induced cAMP a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50463986(CHEMBL4246185)
Affinity DataEC50:  32nMAssay Description:Agonist activity at human dopamine D2 receptor /mGluR5a (unknown origin) expressed in HEK293T cells assessed as reduction in forskolin-induced cAMP a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50018958(CHEBI:75401 | QUINPIROLE)
Affinity DataEC50:  1.90nMAssay Description:Agonist activity at human dopamine D2 receptor /mGluR5a (unknown origin) expressed in HEK293T cells assessed as reduction in forskolin-induced cAMP a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50463982(CHEMBL4239987)
Affinity DataEC50:  7.60nMAssay Description:Agonist activity at human dopamine D2 receptor expressed in HEK293T cells assessed as reduction in forskolin-induced cAMP accumulation preincubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50463982(CHEMBL4239987)
Affinity DataEC50:  20nMAssay Description:Agonist activity at human dopamine D2 receptor /mGluR5a (unknown origin) expressed in HEK293T cells assessed as reduction in forskolin-induced cAMP a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50018958(CHEBI:75401 | QUINPIROLE)
Affinity DataEC50:  1.80nMAssay Description:Agonist activity at human dopamine D2 receptor expressed in HEK293T cells assessed as reduction in forskolin-induced cAMP accumulation preincubated f...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Academy of Scientific and Innovative Research (Acsir)

Curated by ChEMBL
LigandPNGBDBM50524364(CHEMBL4563363)
Affinity DataEC50:  100nMAssay Description:Agonist activity at recombinant human Gs-coupled H2 receptor expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP accumulat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Academy of Scientific and Innovative Research (Acsir)

Curated by ChEMBL
LigandPNGBDBM50524366(CHEMBL4576986)
Affinity DataEC50:  80nMAssay Description:Agonist activity at recombinant human Gs-coupled H2 receptor expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP accumulat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Academy of Scientific and Innovative Research (Acsir)

Curated by ChEMBL
LigandPNGBDBM50524367(CHEMBL4580450)
Affinity DataEC50:  840nMAssay Description:Agonist activity at recombinant human Gs-coupled H2 receptor expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP accumulat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Academy of Scientific and Innovative Research (Acsir)

Curated by ChEMBL
LigandPNGBDBM50524368(CHEMBL4452406)
Affinity DataEC50:  250nMAssay Description:Agonist activity at recombinant human Gs-coupled H2 receptor expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP accumulat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Academy of Scientific and Innovative Research (Acsir)

Curated by ChEMBL
LigandPNGBDBM50524363(CHEMBL4585616)
Affinity DataEC50:  360nMAssay Description:Agonist activity at recombinant human Gs-coupled H2 receptor expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP accumulat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Academy of Scientific and Innovative Research (Acsir)

Curated by ChEMBL
LigandPNGBDBM50524369(CHEMBL4567405)
Affinity DataEC50:  2.12E+3nMAssay Description:Agonist activity at recombinant human Gs-coupled H2 receptor expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP accumulat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Academy of Scientific and Innovative Research (Acsir)

Curated by ChEMBL
LigandPNGBDBM50524370(CHEMBL4568452)
Affinity DataEC50:  1.39E+3nMAssay Description:Agonist activity at recombinant human Gs-coupled H2 receptor expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP accumulat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Academy of Scientific and Innovative Research (Acsir)

Curated by ChEMBL
LigandPNGBDBM50524364(CHEMBL4563363)
Affinity DataEC50:  95nMAssay Description:Agonist activity at recombinant human Gs-coupled H2 receptor expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP accumulat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Academy of Scientific and Innovative Research (Acsir)

Curated by ChEMBL
LigandPNGBDBM50524371(CHEMBL4456972)
Affinity DataEC50:  76nMAssay Description:Agonist activity at recombinant human Gs-coupled H2 receptor expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP accumulat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Academy of Scientific and Innovative Research (Acsir)

Curated by ChEMBL
LigandPNGBDBM50524367(CHEMBL4580450)
Affinity DataEC50:  840nMAssay Description:Agonist activity at recombinant human Gs-coupled H2 receptor expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP accumulat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Academy of Scientific and Innovative Research (Acsir)

Curated by ChEMBL
LigandPNGBDBM50524363(CHEMBL4585616)
Affinity DataEC50:  363nMAssay Description:Agonist activity at recombinant human Gs-coupled H2 receptor expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP accumulat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Academy of Scientific and Innovative Research (Acsir)

Curated by ChEMBL
LigandPNGBDBM50524369(CHEMBL4567405)
Affinity DataEC50:  2.14E+3nMAssay Description:Agonist activity at recombinant human Gs-coupled H2 receptor expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP accumulat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Academy of Scientific and Innovative Research (Acsir)

Curated by ChEMBL
LigandPNGBDBM50524368(CHEMBL4452406)
Affinity DataEC50:  245nMAssay Description:Agonist activity at recombinant human Gs-coupled H2 receptor expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP accumulat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Academy of Scientific and Innovative Research (Acsir)

Curated by ChEMBL
LigandPNGBDBM50524371(CHEMBL4456972)
Affinity DataEC50:  80nMAssay Description:Agonist activity at recombinant human Gs-coupled H2 receptor expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP accumulat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Academy of Scientific and Innovative Research (Acsir)

Curated by ChEMBL
LigandPNGBDBM50524372(CHEMBL4565419)
Affinity DataEC50:  5.29E+3nMAssay Description:Agonist activity at recombinant human Gs-coupled H2 receptor expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP accumulat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Academy of Scientific and Innovative Research (Acsir)

Curated by ChEMBL
LigandPNGBDBM50524377(CHEMBL4519923)
Affinity DataEC50:  5.18E+3nMAssay Description:Agonist activity at recombinant human Gs-coupled H2 receptor expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP accumulat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Academy of Scientific and Innovative Research (Acsir)

Curated by ChEMBL
LigandPNGBDBM50524370(CHEMBL4568452)
Affinity DataEC50:  1.29E+3nMAssay Description:Agonist activity at recombinant human Gs-coupled H2 receptor expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP accumulat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Academy of Scientific and Innovative Research (Acsir)

Curated by ChEMBL
LigandPNGBDBM50524366(CHEMBL4576986)
Affinity DataEC50:  78nMAssay Description:Agonist activity at recombinant human Gs-coupled H2 receptor expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP accumulat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Academy of Scientific and Innovative Research (Acsir)

Curated by ChEMBL
LigandPNGBDBM50524377(CHEMBL4519923)
Affinity DataEC50:  5.25E+3nMAssay Description:Agonist activity at recombinant human Gs-coupled H2 receptor expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP accumulat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Academy of Scientific and Innovative Research (Acsir)

Curated by ChEMBL
LigandPNGBDBM50524362(CHEMBL4467878)
Affinity DataEC50:  891nMAssay Description:Agonist activity at recombinant human Gs-coupled H2 receptor expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP accumulat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Academy of Scientific and Innovative Research (Acsir)

Curated by ChEMBL
LigandPNGBDBM50524372(CHEMBL4565419)
Affinity DataEC50:  5.37E+3nMAssay Description:Agonist activity at recombinant human Gs-coupled H2 receptor expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP accumulat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Academy of Scientific and Innovative Research (Acsir)

Curated by ChEMBL
LigandPNGBDBM50524362(CHEMBL4467878)
Affinity DataEC50:  880nMAssay Description:Agonist activity at recombinant human Gs-coupled H2 receptor expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP accumulat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
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