Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 39 with Last Name = 'regier' and Initial = 'rc'
TargetPhenylethanolamine N-methyltransferase(Human)
University of Kansas

LigandPNGBDBM13014(7,8-Dichloro-1,2,3,4-tetrahydro-isoquinoline; hydr...)
Affinity DataKi:  3.10nM ΔG°:  -50.5kJ/molepH: 8.0 T: 37°CAssay Description:Enzyme activity is determined by measuring the amount of 3H incorporated into the substrate during the reaction. AdoMet/[methyl-3H]AdoMet serves as a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank
MMDB
PDB3D3D Structure (crystal)

TargetPhenylethanolamine N-methyltransferase(Human)
University of Kansas

LigandPNGBDBM13014(7,8-Dichloro-1,2,3,4-tetrahydro-isoquinoline; hydr...)
Affinity DataKi:  3.10nMAssay Description:Binding affinity to human PNMTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank
MMDB
PDB3D3D Structure (crystal)

TargetPhenylethanolamine N-methyltransferase(Human)
University of Kansas

LigandPNGBDBM13027(3-(hydroxymethyl)-N-(2,2,2-trifluoroethyl)-1,2,3,4...)
Affinity DataKi:  23nM ΔG°:  -45.4kJ/molepH: 8.0 T: 37°CAssay Description:Enzyme activity is determined by measuring the amount of 3H incorporated into the substrate during the reaction. AdoMet/[methyl-3H]AdoMet serves as a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPhenylethanolamine N-methyltransferase(Human)
University of Kansas

LigandPNGBDBM13023(3-(hydroxymethyl)-1,2,3,4-tetrahydroisoquinoline-7...)
Affinity DataKi:  52nM ΔG°:  -43.2kJ/molepH: 8.0 T: 37°CAssay Description:Enzyme activity is determined by measuring the amount of 3H incorporated into the substrate during the reaction. AdoMet/[methyl-3H]AdoMet serves as a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPhenylethanolamine N-methyltransferase(Human)
University of Kansas

LigandPNGBDBM50072977(7-Bromo-1,2,3,4-tetrahydro-isoquinoline | 7-bromo-...)
Affinity DataKi:  56nMAssay Description:Binding affinity to human PNMTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPhenylethanolamine N-methyltransferase(Human)
University of Kansas

LigandPNGBDBM13025(7-sulfonamide-THIQ 15 | CHEMBL176112 | N-(4-chloro...)
Affinity DataKi:  63nM ΔG°:  -42.8kJ/molepH: 8.0 T: 37°CAssay Description:Enzyme activity is determined by measuring the amount of 3H incorporated into the substrate during the reaction. AdoMet/[methyl-3H]AdoMet serves as a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetPhenylethanolamine N-methyltransferase(Human)
University of Kansas

LigandPNGBDBM50072991(7-Nitro-1,2,3,4-tetrahydro-isoquinoline | 7-nitro-...)
Affinity DataKi:  120nMAssay Description:Binding affinity to human PNMTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPhenylethanolamine N-methyltransferase(Human)
University of Kansas

LigandPNGBDBM13026(3-(fluoromethyl)-N-(2,2,2-trifluoroethyl)-1,2,3,4-...)
Affinity DataKi:  130nM ΔG°:  -40.9kJ/molepH: 8.0 T: 37°CAssay Description:Enzyme activity is determined by measuring the amount of 3H incorporated into the substrate during the reaction. AdoMet/[methyl-3H]AdoMet serves as a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPhenylethanolamine N-methyltransferase(Human)
University of Kansas

LigandPNGBDBM13022(3-(fluoromethyl)-1,2,3,4-tetrahydroisoquinoline-7-...)
Affinity DataKi:  150nM ΔG°:  -40.5kJ/molepH: 8.0 T: 37°CAssay Description:Enzyme activity is determined by measuring the amount of 3H incorporated into the substrate during the reaction. AdoMet/[methyl-3H]AdoMet serves as a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPhenylethanolamine N-methyltransferase(Human)
University of Kansas

LigandPNGBDBM50199508(7-bromo-1,2,3,4-tetrahydrobenzo[h]isoquinoline | C...)
Affinity DataKi:  220nMAssay Description:Binding affinity to human PNMTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPhenylethanolamine N-methyltransferase(Human)
University of Kansas

LigandPNGBDBM13028(3-(fluoromethyl)-N-(3,3,3-trifluoropropyl)-1,2,3,4...)
Affinity DataKi:  220nM ΔG°:  -39.5kJ/molepH: 8.0 T: 37°CAssay Description:Enzyme activity is determined by measuring the amount of 3H incorporated into the substrate during the reaction. AdoMet/[methyl-3H]AdoMet serves as a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetPhenylethanolamine N-methyltransferase(Human)
University of Kansas

LigandPNGBDBM13024(7-sulfonamide-THIQ 14 | CHEMBL290890 | N-(4-chloro...)
Affinity DataKi:  270nM ΔG°:  -39.0kJ/molepH: 8.0 T: 37°CAssay Description:Enzyme activity is determined by measuring the amount of 3H incorporated into the substrate during the reaction. AdoMet/[methyl-3H]AdoMet serves as a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPhenylethanolamine N-methyltransferase(Human)
University of Kansas

LigandPNGBDBM13017(1,2,3,4-tetrahydroisoquinoline-7-sulfonamide | CHE...)
Affinity DataKi:  280nM ΔG°:  -38.9kJ/molepH: 8.0 T: 37°CAssay Description:Enzyme activity is determined by measuring the amount of 3H incorporated into the substrate during the reaction. AdoMet/[methyl-3H]AdoMet serves as a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank
MMDB
PDB3D3D Structure (crystal)

TargetPhenylethanolamine N-methyltransferase(Human)
University of Kansas

LigandPNGBDBM13017(1,2,3,4-tetrahydroisoquinoline-7-sulfonamide | CHE...)
Affinity DataKi:  280nMAssay Description:Binding affinity to human PNMTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank
MMDB
PDB3D3D Structure (crystal)

TargetPhenylethanolamine N-methyltransferase(Human)
University of Kansas

LigandPNGBDBM13018(7-methanesulfonyl-1,2,3,4-tetrahydroisoquinoline |...)
Affinity DataKi:  790nM ΔG°:  -36.2kJ/molepH: 8.0 T: 37°CAssay Description:Enzyme activity is determined by measuring the amount of 3H incorporated into the substrate during the reaction. AdoMet/[methyl-3H]AdoMet serves as a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPhenylethanolamine N-methyltransferase(Human)
University of Kansas

LigandPNGBDBM50199511(7-nitro-1,2,3,4-tetrahydrobenzo[h]isoquinoline | C...)
Affinity DataKi:  900nMAssay Description:Binding affinity to human PNMTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPhenylethanolamine N-methyltransferase(Human)
University of Kansas

LigandPNGBDBM50199512(1,2,3,4-tetrahydrobenzo[h]isoquinolin-7-ol | CHEMB...)
Affinity DataKi:  910nMAssay Description:Binding affinity to human PNMTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPhenylethanolamine N-methyltransferase(Human)
University of Kansas

LigandPNGBDBM13041(3-(fluoromethyl)-7-methanesulfonyl-1,2,3,4-tetrahy...)
Affinity DataKi:  1.10E+3nM ΔG°:  -35.4kJ/molepH: 8.0 T: 37°CAssay Description:Enzyme activity is determined by measuring the amount of 3H incorporated into the substrate during the reaction. AdoMet/[methyl-3H]AdoMet serves as a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPhenylethanolamine N-methyltransferase(Human)
University of Kansas

LigandPNGBDBM13034(((+/-)-3-Fluoromethyl-7-(3,3,3-trifluoropropylsulf...)
Affinity DataKi:  1.30E+3nM ΔG°:  -34.9kJ/molepH: 8.0 T: 37°CAssay Description:Enzyme activity is determined by measuring the amount of 3H incorporated into the substrate during the reaction. AdoMet/[methyl-3H]AdoMet serves as a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPhenylethanolamine N-methyltransferase(Human)
University of Kansas

LigandPNGBDBM13040(3-(fluoromethyl)-7-[(2,2,2-trifluoroethane)sulfony...)
Affinity DataKi:  1.40E+3nM ΔG°:  -34.8kJ/molepH: 8.0 T: 37°CAssay Description:Enzyme activity is determined by measuring the amount of 3H incorporated into the substrate during the reaction. AdoMet/[methyl-3H]AdoMet serves as a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPhenylethanolamine N-methyltransferase(Human)
University of Kansas

LigandPNGBDBM13030(7-sulfonamide-THIQ 20 | CHEMBL177861 | N-ethyl-3-(...)
Affinity DataKi:  1.40E+3nM ΔG°:  -34.8kJ/molepH: 8.0 T: 37°CAssay Description:Enzyme activity is determined by measuring the amount of 3H incorporated into the substrate during the reaction. AdoMet/[methyl-3H]AdoMet serves as a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPhenylethanolamine N-methyltransferase(Human)
University of Kansas

LigandPNGBDBM50072989(1,2,3,4-Tetrahydro-isoquinoline-7-carbonitrile | 1...)
Affinity DataKi:  1.50E+3nMAssay Description:Binding affinity to human PNMTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPhenylethanolamine N-methyltransferase(Human)
University of Kansas

LigandPNGBDBM13031(3-(fluoromethyl)-N-propyl-1,2,3,4-tetrahydroisoqui...)
Affinity DataKi:  1.70E+3nM ΔG°:  -34.3kJ/molepH: 8.0 T: 37°CAssay Description:Enzyme activity is determined by measuring the amount of 3H incorporated into the substrate during the reaction. AdoMet/[methyl-3H]AdoMet serves as a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPhenylethanolamine N-methyltransferase(Human)
University of Kansas

LigandPNGBDBM50199509(7-methoxy-1,2,3,4-tetrahydrobenzo[h]isoquinoline |...)
Affinity DataKi:  2.10E+3nMAssay Description:Binding affinity to human PNMTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPhenylethanolamine N-methyltransferase(Human)
University of Kansas

LigandPNGBDBM50199506(1,2,3,4-tetrahydrobenzo[h]isoquinoline-7-carbonitr...)
Affinity DataKi:  2.30E+3nMAssay Description:Binding affinity to human PNMTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPhenylethanolamine N-methyltransferase(Human)
University of Kansas

LigandPNGBDBM13037(3-(fluoromethyl)-7-(propane-1-sulfonyl)-1,2,3,4-te...)
Affinity DataKi:  2.40E+3nM ΔG°:  -33.4kJ/molepH: 8.0 T: 37°CAssay Description:Enzyme activity is determined by measuring the amount of 3H incorporated into the substrate during the reaction. AdoMet/[methyl-3H]AdoMet serves as a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPhenylethanolamine N-methyltransferase(Human)
University of Kansas

LigandPNGBDBM13029(3-(fluoromethyl)-N-methyl-1,2,3,4-tetrahydroisoqui...)
Affinity DataKi:  3.70E+3nM ΔG°:  -32.3kJ/molepH: 8.0 T: 37°CAssay Description:Enzyme activity is determined by measuring the amount of 3H incorporated into the substrate during the reaction. AdoMet/[methyl-3H]AdoMet serves as a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPhenylethanolamine N-methyltransferase(Human)
University of Kansas

LigandPNGBDBM13032(3-(fluoromethyl)-N-(2-methoxyethyl)-1,2,3,4-tetrah...)
Affinity DataKi:  5.10E+3nM ΔG°:  -31.4kJ/molepH: 8.0 T: 37°CAssay Description:Enzyme activity is determined by measuring the amount of 3H incorporated into the substrate during the reaction. AdoMet/[methyl-3H]AdoMet serves as a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPhenylethanolamine N-methyltransferase(Human)
University of Kansas

LigandPNGBDBM13016(1,2,3,4-tetrahydroisoquinoline | CHEMBL14346 | THI...)
Affinity DataKi:  5.80E+3nM ΔG°:  -31.1kJ/molepH: 8.0 T: 37°CAssay Description:Enzyme activity is determined by measuring the amount of 3H incorporated into the substrate during the reaction. AdoMet/[methyl-3H]AdoMet serves as a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPhenylethanolamine N-methyltransferase(Human)
University of Kansas

LigandPNGBDBM13016(1,2,3,4-tetrahydroisoquinoline | CHEMBL14346 | THI...)
Affinity DataKi:  5.80E+3nMAssay Description:Binding affinity to human PNMTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPhenylethanolamine N-methyltransferase(Human)
University of Kansas

LigandPNGBDBM13021(7-(trichloromethane)sulfonyl-1,2,3,4-tetrahydroiso...)
Affinity DataKi:  6.30E+3nM ΔG°:  -30.9kJ/molepH: 8.0 T: 37°CAssay Description:Enzyme activity is determined by measuring the amount of 3H incorporated into the substrate during the reaction. AdoMet/[methyl-3H]AdoMet serves as a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPhenylethanolamine N-methyltransferase(Human)
University of Kansas

LigandPNGBDBM13020(7-(prop-2-ene-1-sulfonyl)-1,2,3,4-tetrahydroisoqui...)
Affinity DataKi:  9.00E+3nM ΔG°:  -30.0kJ/molepH: 8.0 T: 37°CAssay Description:Enzyme activity is determined by measuring the amount of 3H incorporated into the substrate during the reaction. AdoMet/[methyl-3H]AdoMet serves as a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPhenylethanolamine N-methyltransferase(Human)
University of Kansas

LigandPNGBDBM13036(((+/-)-7-Ethylsulfonyl-3-fluoromethyl-1,2,3,4-tetr...)
Affinity DataKi:  1.40E+4nM ΔG°:  -28.8kJ/molepH: 8.0 T: 37°CAssay Description:Enzyme activity is determined by measuring the amount of 3H incorporated into the substrate during the reaction. AdoMet/[methyl-3H]AdoMet serves as a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPhenylethanolamine N-methyltransferase(Human)
University of Kansas

LigandPNGBDBM13038(7-(butane-1-sulfonyl)-3-(fluoromethyl)-1,2,3,4-tet...)
Affinity DataKi:  1.80E+4nM ΔG°:  -28.2kJ/molepH: 8.0 T: 37°CAssay Description:Enzyme activity is determined by measuring the amount of 3H incorporated into the substrate during the reaction. AdoMet/[methyl-3H]AdoMet serves as a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPhenylethanolamine N-methyltransferase(Human)
University of Kansas

LigandPNGBDBM13019(7-(benzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline...)
Affinity DataKi:  2.30E+4nM ΔG°:  -27.5kJ/molepH: 8.0 T: 37°CAssay Description:Enzyme activity is determined by measuring the amount of 3H incorporated into the substrate during the reaction. AdoMet/[methyl-3H]AdoMet serves as a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPhenylethanolamine N-methyltransferase(Human)
University of Kansas

LigandPNGBDBM13033(((+/-)-3-Fluoromethyl-7-(4-chlorobenzylsulfonyl)-1...)
Affinity DataKi:  3.20E+4nM ΔG°:  -26.7kJ/molepH: 8.0 T: 37°CAssay Description:Enzyme activity is determined by measuring the amount of 3H incorporated into the substrate during the reaction. AdoMet/[methyl-3H]AdoMet serves as a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetPhenylethanolamine N-methyltransferase(Human)
University of Kansas

LigandPNGBDBM50199507(1,2,3,4-tetrahydrobenzo[h]isoquinoline-7-sulfonami...)
Affinity DataKi:  3.30E+4nMAssay Description:Binding affinity to human PNMTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPhenylethanolamine N-methyltransferase(Human)
University of Kansas

LigandPNGBDBM13035(((+/-)-3-Fluoromethyl-7-(4,4,4-trifluorobutylsulfo...)
Affinity DataKi:  6.70E+4nM ΔG°:  -24.8kJ/molepH: 8.0 T: 37°CAssay Description:Enzyme activity is determined by measuring the amount of 3H incorporated into the substrate during the reaction. AdoMet/[methyl-3H]AdoMet serves as a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPhenylethanolamine N-methyltransferase(Human)
University of Kansas

LigandPNGBDBM13039(3-(fluoromethyl)-7-[(3-methoxypropane)sulfonyl]-1,...)
Affinity DataKi:  7.20E+4nM ΔG°:  -24.6kJ/molepH: 8.0 T: 37°CAssay Description:Enzyme activity is determined by measuring the amount of 3H incorporated into the substrate during the reaction. AdoMet/[methyl-3H]AdoMet serves as a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed