Compile Data Set for Download or QSAR
Report error Found 2486 with Last Name = 'rehwinkel' and Initial = 'h'
TargetGlucocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM18207(dexamethasone (tetramethyl-rhodamine conjugated ) ...)
Affinity DataEC50:  7.94nMAssay Description:Transactivation activity at glucocorticoid receptor in human HeLa cells assessed as induction of MMTV promoter activity by luciferase reporter gene a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50172022(4-(5-Fluoro-2-hydroxy-phenyl)-2-hydroxy-4-methyl-2...)
Affinity DataEC50:  25.1nMAssay Description:Transactivation activity at glucocorticoid receptor in human HeLa cells assessed as induction of MMTV promoter activity by luciferase reporter gene a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50416868(CHEMBL1257453)
Affinity DataEC50:  79.4nMAssay Description:Transactivation activity at glucocorticoid receptor in human HeLa cells assessed as induction of MMTV promoter activity by luciferase reporter gene a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50416873(CHEMBL1257454)
Affinity DataEC50:  25.1nMAssay Description:Transactivation activity at glucocorticoid receptor in human HeLa cells assessed as induction of MMTV promoter activity by luciferase reporter gene a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50416869(CHEMBL1257572)
Affinity DataEC50:  12.6nMAssay Description:Transactivation activity at glucocorticoid receptor in human HeLa cells assessed as induction of MMTV promoter activity by luciferase reporter gene a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50201099(4-(2,3-dihydrobenzofuran-7-yl)-2-hydroxy-4-methyl-...)
Affinity DataEC50:  12.6nMAssay Description:Transactivation activity at glucocorticoid receptor in human HeLa cells assessed as induction of MMTV promoter activity by luciferase reporter gene a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50250114(CHEMBL4104286)
Affinity DataIC50: 0.0200nMAssay Description:Transrepression of glucocorticoid receptor in PMA-stimulated human ChaGoK1 cells expressing TRE-LacZ construct assessed as inhibition of AP-1 mediate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50250125(CHEMBL4061359)
Affinity DataIC50: 0.0290nMAssay Description:Transrepression of glucocorticoid receptor in PMA-stimulated human ChaGoK1 cells expressing TRE-LacZ construct assessed as inhibition of AP-1 mediate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50203432(CHEMBL3911831)
Affinity DataIC50: 0.0300nMAssay Description:Agonist activity at glucocorticoid receptor in human ChaGoK1 cells assessed as inhibition of AP1-mediated transcriptional activity by measuring reduc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2018
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50250115(CHEMBL4086388)
Affinity DataIC50: 0.0320nMAssay Description:Transrepression of glucocorticoid receptor in human PBMC assessed as inhibition of LPS induced TNF alpha release preincubated for 45 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM141378(US8916600, 12 | US9738632, Example 12)
Affinity DataIC50: 0.0370nMAssay Description:Transrepression of glucocorticoid receptor in PMA-stimulated human ChaGoK1 cells expressing TRE-LacZ construct assessed as inhibition of AP-1 mediate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50354849(Flovent hfa | Cutivate | Flovent | Flovent diskus ...)
Affinity DataIC50: 0.0400nMAssay Description:Transrepression of glucocorticoid receptor in human PBMC assessed as inhibition of LPS induced TNF alpha release preincubated for 45 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50203441(CHEMBL3973775)
Affinity DataIC50: 0.0400nMAssay Description:Agonist activity at glucocorticoid receptor in human ChaGoK1 cells assessed as inhibition of AP1-mediated transcriptional activity by measuring reduc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2018
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50203418(CHEMBL3902818)
Affinity DataIC50: 0.0400nMAssay Description:Agonist activity at glucocorticoid receptor in human ChaGoK1 cells assessed as inhibition of AP1-mediated transcriptional activity by measuring reduc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2018
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50354849(Flovent hfa | Cutivate | Flovent | Flovent diskus ...)
Affinity DataIC50: 0.0440nMAssay Description:Transrepression of glucocorticoid receptor in human PBMC assessed as inhibition of LPS induced TNF alpha release preincubated for 45 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50250112(CHEMBL4072756)
Affinity DataIC50: 0.0490nMAssay Description:Transrepression of glucocorticoid receptor in human PBMC assessed as inhibition of LPS induced TNF alpha release preincubated for 45 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlucocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50203413(CHEMBL3920760)
Affinity DataIC50: 0.0500nMAssay Description:Agonist activity at glucocorticoid receptor in human ChaGoK1 cells assessed as inhibition of AP1-mediated transcriptional activity by measuring reduc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2018
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM141371(US8916600, 5 | US9738632, Example 5)
Affinity DataIC50: 0.0510nMAssay Description:Transrepression of glucocorticoid receptor in PMA-stimulated human ChaGoK1 cells expressing TRE-LacZ construct assessed as inhibition of AP-1 mediate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM141372(US8916600, 6 | US9738632, Example 6)
Affinity DataIC50: 0.0560nMAssay Description:Transrepression of glucocorticoid receptor in PMA-stimulated human ChaGoK1 cells expressing TRE-LacZ construct assessed as inhibition of AP-1 mediate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM141379(US8916600, 13 | US9738632, Example 13)
Affinity DataIC50: 0.0620nMAssay Description:Transrepression of glucocorticoid receptor in PMA-stimulated human ChaGoK1 cells expressing TRE-LacZ construct assessed as inhibition of AP-1 mediate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50250126(CHEMBL4094154)
Affinity DataIC50: 0.0660nMAssay Description:Transrepression of glucocorticoid receptor in human PBMC assessed as inhibition of LPS induced TNF alpha release preincubated for 45 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50250125(CHEMBL4061359)
Affinity DataIC50: 0.0730nMAssay Description:Transrepression of glucocorticoid receptor in human PBMC assessed as inhibition of LPS induced TNF alpha release preincubated for 45 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50250114(CHEMBL4104286)
Affinity DataIC50: 0.0800nMAssay Description:Transrepression of glucocorticoid receptor in human PBMC assessed as inhibition of LPS induced TNF alpha release preincubated for 45 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50203430(CHEMBL3901719)
Affinity DataIC50: 0.0800nMAssay Description:Agonist activity at glucocorticoid receptor in human ChaGoK1 cells assessed as inhibition of AP1-mediated transcriptional activity by measuring reduc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2018
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50203423(CHEMBL3960682)
Affinity DataIC50: 0.0900nMAssay Description:Agonist activity at glucocorticoid receptor in human ChaGoK1 cells assessed as inhibition of AP1-mediated transcriptional activity by measuring reduc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2018
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50203435(CHEMBL3940724)
Affinity DataIC50: 0.0900nMAssay Description:Agonist activity at glucocorticoid receptor in human ChaGoK1 cells assessed as inhibition of AP1-mediated transcriptional activity by measuring reduc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2018
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Rat)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM141379(US8916600, 13 | US9738632, Example 13)
Affinity DataIC50: 0.100nMAssay Description:Transrepression of glucocorticoid receptor in Wistar rat PBMC assessed as inhibition of LPS induced TNF alpha release preincubated for 45 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50250115(CHEMBL4086388)
Affinity DataIC50: 0.101nMAssay Description:Transrepression of glucocorticoid receptor in human PBMC assessed as inhibition of LPS induced TNF alpha release preincubated for 45 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50250118(CHEMBL4070346)
Affinity DataIC50: 0.120nMAssay Description:Transrepression of glucocorticoid receptor in PMA-stimulated human ChaGoK1 cells expressing TRE-LacZ construct assessed as inhibition of AP-1 mediate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50203419(CHEMBL3915997)
Affinity DataIC50: 0.130nMAssay Description:Transrepression of glucocorticoid receptor in PMA-stimulated human ChaGoK1 cells expressing TRE-LacZ construct assessed as inhibition of AP-1 mediate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50203419(CHEMBL3915997)
Affinity DataIC50: 0.130nMAssay Description:Agonist activity at glucocorticoid receptor in human ChaGoK1 cells assessed as inhibition of AP1-mediated transcriptional activity by measuring reduc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2018
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50250126(CHEMBL4094154)
Affinity DataIC50: 0.132nMAssay Description:Transrepression of glucocorticoid receptor in human PBMC assessed as inhibition of LPS induced TNF alpha release preincubated for 45 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Rat)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50354849(Flovent hfa | Cutivate | Flovent | Flovent diskus ...)
Affinity DataIC50: 0.140nMAssay Description:Transrepression of glucocorticoid receptor in Wistar rat PBMC assessed as inhibition of LPS induced TNF alpha release preincubated for 45 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Rat)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50250112(CHEMBL4072756)
Affinity DataIC50: 0.140nMAssay Description:Transrepression of glucocorticoid receptor in Wistar rat PBMC assessed as inhibition of LPS induced TNF alpha release preincubated for 45 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlucocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50250119(CHEMBL4098641)
Affinity DataIC50: 0.150nMAssay Description:Transrepression of glucocorticoid receptor in human PBMC assessed as inhibition of LPS induced TNF alpha release preincubated for 45 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50250116(CHEMBL4066614)
Affinity DataIC50: 0.156nMAssay Description:Transrepression of glucocorticoid receptor in human PBMC assessed as inhibition of LPS induced TNF alpha release preincubated for 45 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50203424(CHEMBL3893393)
Affinity DataIC50: 0.158nMAssay Description:Transrepression activity at glucocorticoid receptor in human THP1 cells assessed as receptor-mediated anti-inflammatory activity by measuring inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2020
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50203424(CHEMBL3893393)
Affinity DataIC50: 0.158nMAssay Description:Transrepression activity at glucocorticoid receptorin human HeLa cells assessed as inhibition of TPA-induced collagenase promoter activity by lucifer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2020
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50250112(CHEMBL4072756)
Affinity DataIC50: 0.160nMAssay Description:Transrepression of glucocorticoid receptor in human PBMC assessed as inhibition of LPS induced TNF alpha release preincubated for 45 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlucocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM141378(US8916600, 12 | US9738632, Example 12)
Affinity DataIC50: 0.170nMAssay Description:Transrepression of glucocorticoid receptor in human PBMC assessed as inhibition of LPS induced TNF alpha release preincubated for 45 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM141368(US8916600, 3 | US8916600, 2 | US9738632, Example 2)
Affinity DataIC50: 0.170nMAssay Description:Transrepression of glucocorticoid receptor in human PBMC assessed as inhibition of LPS induced TNF alpha release preincubated for 45 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM141375(US8916600, 9 | US9738632, Example 9)
Affinity DataIC50: 0.190nMAssay Description:Transrepression of glucocorticoid receptor in PMA-stimulated human ChaGoK1 cells expressing TRE-LacZ construct assessed as inhibition of AP-1 mediate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM141367(US8916600, 4 | US8916600, 1 | US9738632, Example 1)
Affinity DataIC50: 0.210nMAssay Description:Transrepression of glucocorticoid receptor in human PBMC assessed as inhibition of LPS induced TNF alpha release preincubated for 45 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50250127(CHEMBL4096557)
Affinity DataIC50: 0.210nMAssay Description:Transrepression of glucocorticoid receptor in PMA-stimulated human ChaGoK1 cells expressing TRE-LacZ construct assessed as inhibition of AP-1 mediate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50203443(CHEMBL3892759)
Affinity DataIC50: 0.210nMAssay Description:Agonist activity at glucocorticoid receptor in human ChaGoK1 cells assessed as inhibition of AP1-mediated transcriptional activity by measuring reduc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2018
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50250118(CHEMBL4070346)
Affinity DataIC50: 0.25nMAssay Description:Transrepression of glucocorticoid receptor in human PBMC assessed as inhibition of LPS induced TNF alpha release preincubated for 45 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50203436(CHEMBL3935790)
Affinity DataIC50: 0.25nMAssay Description:Agonist activity at glucocorticoid receptor in human ChaGoK1 cells assessed as inhibition of AP1-mediated transcriptional activity by measuring reduc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2018
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Rat)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM141378(US8916600, 12 | US9738632, Example 12)
Affinity DataIC50: 0.290nMAssay Description:Transrepression of glucocorticoid receptor in Wistar rat PBMC assessed as inhibition of LPS induced TNF alpha release preincubated for 45 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Rat)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM141372(US8916600, 6 | US9738632, Example 6)
Affinity DataIC50: 0.300nMAssay Description:Transrepression of glucocorticoid receptor in Wistar rat PBMC assessed as inhibition of LPS induced TNF alpha release preincubated for 45 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50250116(CHEMBL4066614)
Affinity DataIC50: 0.322nMAssay Description:Transrepression of glucocorticoid receptor in human PBMC assessed as inhibition of LPS induced TNF alpha release preincubated for 45 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed
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