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TargetSodium-dependent noradrenaline transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50182758(CHEMBL3819243)
Affinity DataIC50: 0.0650nMAssay Description:Inhibition of human NET expressed in CHO cells assessed as [3H]-Norepinephrine reuptake incubated for 45 mins measured after 30 mins by topcount meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2017
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50182757(CHEMBL3819201)
Affinity DataIC50: 0.0790nMAssay Description:Inhibition of human NET expressed in CHO cells assessed as [3H]-Norepinephrine reuptake incubated for 45 mins measured after 30 mins by topcount meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2017
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50182755(CHEMBL3818117)
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of human NET expressed in CHO cells assessed as [3H]-Norepinephrine reuptake incubated for 45 mins measured after 30 mins by topcount meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2017
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM97478(US8470816, 91)
Affinity DataIC50: 0.0920nMpH: 7.4Assay Description:IM-9 cells (2×10^5 cells/mL) were cultured for 3 days after inoculation, and centrifuged at 500×g for 10 min to give cell pellets. The ob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2013
Entry Details
Go to US Patent

TargetSodium-dependent noradrenaline transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50182754(CHEMBL3817915)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human NET expressed in CHO cells assessed as [3H]-Norepinephrine reuptake incubated for 45 mins measured after 30 mins by topcount meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2017
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50182753(CHEMBL3818953)
Affinity DataIC50: 0.130nMAssay Description:Inhibition of human NET expressed in CHO cells assessed as [3H]-Norepinephrine reuptake incubated for 45 mins measured after 30 mins by topcount meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2017
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50182763(CHEMBL3818901)
Affinity DataIC50: 0.210nMAssay Description:Inhibition of human NET expressed in CHO cells assessed as [3H]-Norepinephrine reuptake incubated for 45 mins measured after 30 mins by topcount meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2017
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM97485(US8470816, 458)
Affinity DataIC50: 0.220nMpH: 7.5Assay Description:CHO cells expressing hNK2 receptor were cultured in a HAM-F12 medium containing 400 ug/mL geneticin, 100 U/mL penicillin, 100 ug/mL streptomycin and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2013
Entry Details
Go to US Patent

TargetSubstance-K receptor(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM97486(US8470816, 464)
Affinity DataIC50: 0.220nMpH: 7.5Assay Description:CHO cells expressing hNK2 receptor were cultured in a HAM-F12 medium containing 400 ug/mL geneticin, 100 U/mL penicillin, 100 ug/mL streptomycin and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2013
Entry Details
Go to US Patent

TargetSubstance-K receptor(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM97489(US8470816, 632)
Affinity DataIC50: 0.220nMpH: 7.5Assay Description:CHO cells expressing hNK2 receptor were cultured in a HAM-F12 medium containing 400 ug/mL geneticin, 100 U/mL penicillin, 100 ug/mL streptomycin and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2013
Entry Details
Go to US Patent

TargetSubstance-K receptor(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM97481(US8470816, 265)
Affinity DataIC50: 0.230nMpH: 7.5Assay Description:CHO cells expressing hNK2 receptor were cultured in a HAM-F12 medium containing 400 ug/mL geneticin, 100 U/mL penicillin, 100 ug/mL streptomycin and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2013
Entry Details
Go to US Patent

TargetSubstance-K receptor(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM97490(US8470816, 633)
Affinity DataIC50: 0.240nMpH: 7.5Assay Description:CHO cells expressing hNK2 receptor were cultured in a HAM-F12 medium containing 400 ug/mL geneticin, 100 U/mL penicillin, 100 ug/mL streptomycin and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2013
Entry Details
Go to US Patent

TargetSubstance-K receptor(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM97483(US8470816, 292)
Affinity DataIC50: 0.25nMpH: 7.5Assay Description:CHO cells expressing hNK2 receptor were cultured in a HAM-F12 medium containing 400 ug/mL geneticin, 100 U/mL penicillin, 100 ug/mL streptomycin and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2013
Entry Details
Go to US Patent

TargetSubstance-K receptor(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM97479(US8470816, 251a)
Affinity DataIC50: 0.310nMpH: 7.5Assay Description:CHO cells expressing hNK2 receptor were cultured in a HAM-F12 medium containing 400 ug/mL geneticin, 100 U/mL penicillin, 100 ug/mL streptomycin and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2013
Entry Details
Go to US Patent

TargetSubstance-K receptor(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM97487(US8470816, 623)
Affinity DataIC50: 0.310nMpH: 7.5Assay Description:CHO cells expressing hNK2 receptor were cultured in a HAM-F12 medium containing 400 ug/mL geneticin, 100 U/mL penicillin, 100 ug/mL streptomycin and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2013
Entry Details
Go to US Patent

TargetSodium-dependent noradrenaline transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50558220(CHEMBL4791288)
Affinity DataIC50: 0.330nMAssay Description:Inhibition of human NET expressed in CHO-K1 cells assessed as inhibition of [3H]-norepinephrine reuptake measured after 45 mins by Microscintillation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098412(CHEMBL3593400)
Affinity DataIC50: 0.330nMAssay Description:Inhibition of human NET expressed in CHOK1 cells incubated for 45 mins by [3H]-norepinephrine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM97491(US8470816, 635)
Affinity DataIC50: 0.360nMpH: 7.5Assay Description:CHO cells expressing hNK2 receptor were cultured in a HAM-F12 medium containing 400 ug/mL geneticin, 100 U/mL penicillin, 100 ug/mL streptomycin and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2013
Entry Details
Go to US Patent

TargetSubstance-K receptor(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM97482(US8470816, 268)
Affinity DataIC50: 0.420nMpH: 7.5Assay Description:CHO cells expressing hNK2 receptor were cultured in a HAM-F12 medium containing 400 ug/mL geneticin, 100 U/mL penicillin, 100 ug/mL streptomycin and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2013
Entry Details
Go to US Patent

TargetSubstance-K receptor(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM97472(US8470816, 18)
Affinity DataIC50: 0.450nMpH: 7.5Assay Description:CHO cells expressing hNK2 receptor were cultured in a HAM-F12 medium containing 400 ug/mL geneticin, 100 U/mL penicillin, 100 ug/mL streptomycin and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2013
Entry Details
Go to US Patent

TargetC-C chemokine receptor type 6(Rhesus macaque)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50463591(CHEMBL4248604)
Affinity DataIC50: 0.450nMAssay Description:Inhibition of monkey CCR6 expressed in CHO cells assessed as decrease in CCL20-induced reduction of forskolin-stimulated cAMP accumulation preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM97488(US8470816, 629)
Affinity DataIC50: 0.550nMpH: 7.5Assay Description:CHO cells expressing hNK2 receptor were cultured in a HAM-F12 medium containing 400 ug/mL geneticin, 100 U/mL penicillin, 100 ug/mL streptomycin and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2013
Entry Details
Go to US Patent

TargetSubstance-K receptor(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM97480(US8470816, 252)
Affinity DataIC50: 0.560nMpH: 7.5Assay Description:CHO cells expressing hNK2 receptor were cultured in a HAM-F12 medium containing 400 ug/mL geneticin, 100 U/mL penicillin, 100 ug/mL streptomycin and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2013
Entry Details
Go to US Patent

TargetSodium-dependent noradrenaline transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50182762(CHEMBL3818471)
Affinity DataIC50: 0.640nMAssay Description:Inhibition of human NET expressed in CHO cells assessed as [3H]-Norepinephrine reuptake incubated for 45 mins measured after 30 mins by topcount meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2017
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098413(CHEMBL3593399)
Affinity DataIC50: 0.770nMAssay Description:Inhibition of human NET expressed in CHOK1 cells incubated for 45 mins by [3H]-norepinephrine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM97478(US8470816, 91)
Affinity DataIC50: 0.790nMpH: 7.5Assay Description:CHO cells expressing hNK2 receptor were cultured in a HAM-F12 medium containing 400 ug/mL geneticin, 100 U/mL penicillin, 100 ug/mL streptomycin and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2013
Entry Details
Go to US Patent

TargetSubstance-K receptor(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM97484(US8470816, 318)
Affinity DataIC50: 0.820nMpH: 7.5Assay Description:CHO cells expressing hNK2 receptor were cultured in a HAM-F12 medium containing 400 ug/mL geneticin, 100 U/mL penicillin, 100 ug/mL streptomycin and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2013
Entry Details
Go to US Patent

TargetSodium-dependent noradrenaline transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50182761(CHEMBL3818345)
Affinity DataIC50: 1nMAssay Description:Inhibition of human NET expressed in CHO cells assessed as [3H]-Norepinephrine reuptake incubated for 45 mins measured after 30 mins by topcount meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2017
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM97475(US8470816, 30)
Affinity DataIC50: 1.10nMpH: 7.5Assay Description:CHO cells expressing hNK2 receptor were cultured in a HAM-F12 medium containing 400 ug/mL geneticin, 100 U/mL penicillin, 100 ug/mL streptomycin and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2013
Entry Details
Go to US Patent

TargetSodium-dependent noradrenaline transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50182759(CHEMBL3819441)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human NET expressed in CHO cells assessed as [3H]-Norepinephrine reuptake incubated for 45 mins measured after 30 mins by topcount meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2017
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50558224(CHEMBL4753874)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human NET expressed in CHO-K1 cells assessed as inhibition of [3H]-norepinephrine reuptake measured after 45 mins by Microscintillation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50182760(CHEMBL3818946)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human NET expressed in CHO cells assessed as [3H]-Norepinephrine reuptake incubated for 45 mins measured after 30 mins by topcount meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2017
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM97477(US8470816, 82)
Affinity DataIC50: 1.5nMpH: 7.4Assay Description:IM-9 cells (2×10^5 cells/mL) were cultured for 3 days after inoculation, and centrifuged at 500×g for 10 min to give cell pellets. The ob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2013
Entry Details
Go to US Patent

TargetSodium-dependent noradrenaline transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50558221(CHEMBL4754287)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human NET expressed in CHO-K1 cells assessed as inhibition of [3H]-norepinephrine reuptake measured after 45 mins by Microscintillation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM97476(US8470816, 31)
Affinity DataIC50: 1.70nMpH: 7.5Assay Description:CHO cells expressing hNK2 receptor were cultured in a HAM-F12 medium containing 400 ug/mL geneticin, 100 U/mL penicillin, 100 ug/mL streptomycin and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2013
Entry Details
Go to US Patent

TargetSodium-dependent noradrenaline transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50558223(CHEMBL4761826)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human NET expressed in CHO-K1 cells assessed as inhibition of [3H]-norepinephrine reuptake measured after 45 mins by Microscintillation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50182764(CHEMBL3819009)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human NET expressed in CHO cells assessed as [3H]-Norepinephrine reuptake incubated for 45 mins measured after 30 mins by topcount meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2017
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM97474(US8470816, 24)
Affinity DataIC50: 2nMpH: 7.5Assay Description:CHO cells expressing hNK2 receptor were cultured in a HAM-F12 medium containing 400 ug/mL geneticin, 100 U/mL penicillin, 100 ug/mL streptomycin and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2013
Entry Details
Go to US Patent

TargetSodium-dependent noradrenaline transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098373(CHEMBL3593395)
Affinity DataIC50: 2nMAssay Description:Inhibition of human NET expressed in CHOK1 cells incubated for 45 mins by [3H]-norepinephrine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098387(CHEMBL3593274)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human NET expressed in CHOK1 cells incubated for 45 mins by [3H]-norepinephrine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM97477(US8470816, 82)
Affinity DataIC50: 2.20nMpH: 7.5Assay Description:CHO cells expressing hNK2 receptor were cultured in a HAM-F12 medium containing 400 ug/mL geneticin, 100 U/mL penicillin, 100 ug/mL streptomycin and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2013
Entry Details
Go to US Patent

TargetSubstance-K receptor(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM97473(US8470816, 21)
Affinity DataIC50: 2.30nMpH: 7.5Assay Description:CHO cells expressing hNK2 receptor were cultured in a HAM-F12 medium containing 400 ug/mL geneticin, 100 U/mL penicillin, 100 ug/mL streptomycin and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2013
Entry Details
Go to US Patent

TargetSodium-dependent noradrenaline transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098410(CHEMBL3593402)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human NET expressed in CHOK1 cells incubated for 45 mins by [3H]-norepinephrine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098410(CHEMBL3593402)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human NET expressed in CHO cells assessed as [3H]-Norepinephrine reuptake incubated for 45 mins measured after 30 mins by topcount meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2017
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50558214(CHEMBL4792902)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human NET expressed in CHO-K1 cells assessed as inhibition of [3H]-norepinephrine reuptake measured after 45 mins by Microscintillation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50558222(CHEMBL4777709)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human NET expressed in CHO-K1 cells assessed as inhibition of [3H]-norepinephrine reuptake measured after 45 mins by Microscintillation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50558225(CHEMBL4752093)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human NET expressed in CHO-K1 cells assessed as inhibition of [3H]-norepinephrine reuptake measured after 45 mins by Microscintillation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50558216(CHEMBL4741247)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human NET expressed in CHO-K1 cells assessed as inhibition of [3H]-norepinephrine reuptake measured after 45 mins by Microscintillation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50558218(CHEMBL4745694)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human NET expressed in CHO-K1 cells assessed as inhibition of [3H]-norepinephrine reuptake measured after 45 mins by Microscintillation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098408(CHEMBL3593404)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human NET expressed in CHOK1 cells incubated for 45 mins by [3H]-norepinephrine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
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