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Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM36536(D153215)
Affinity DataEC50:  243nMAssay Description:In vitro biochemical assay using scavenger decapping enzyme (DcpS) as a target and cell based assay using SMN2 b-lactamase NSC-34 cell reporter gene.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2011
Entry Details Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM36535(D157554)
Affinity DataEC50:  921nMAssay Description:In vitro biochemical assay using scavenger decapping enzyme (DcpS) as a target and cell based assay using SMN2 b-lactamase NSC-34 cell reporter gene.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2011
Entry Details Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM36534(D156095)
Affinity DataEC50:  104nMAssay Description:In vitro biochemical assay using scavenger decapping enzyme (DcpS) as a target and cell based assay using SMN2 b-lactamase NSC-34 cell reporter gene.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2011
Entry Details Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM50232538(D156844 | CHEMBL251429 | 5-((1-(2-fluorobenzyl)pip...)
Affinity DataIC50: 7.62nM EC50:  4nMAssay Description:In vitro biochemical assay using scavenger decapping enzyme (DcpS) as a target and cell based assay using SMN2 b-lactamase NSC-34 cell reporter gene.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM36533(D157555)
Affinity DataIC50: 9.38nM EC50:  108nMAssay Description:In vitro biochemical assay using scavenger decapping enzyme (DcpS) as a target and cell based assay using SMN2 b-lactamase NSC-34 cell reporter gene.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2011
Entry Details Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM36531(D158963)
Affinity DataIC50: 23.4nM EC50:  223nMAssay Description:In vitro biochemical assay using scavenger decapping enzyme (DcpS) as a target and cell based assay using SMN2 b-lactamase NSC-34 cell reporter gene.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2011
Entry Details Article
PubMed
TargetActin [R335K](Baker's yeast)
Novartis Pharma

LigandPNGBDBM65515(LAT-A | 76343-93-6 | LatA | Latrunculin A)
Affinity DataIC50: 40nMT: 2°CAssay Description:Saturated ACT1 wild type (WT) as well as engineered ACT1 R183K (R183K) and ACT1 R335K (R335K) cultures were adjusted to 10 OD600 and 3 uL of serial 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM36530(D157493)
Affinity DataIC50: 43.9nM EC50:  67nMAssay Description:In vitro biochemical assay using scavenger decapping enzyme (DcpS) as a target and cell based assay using SMN2 b-lactamase NSC-34 cell reporter gene.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetActin(Baker's yeast)
Novartis Pharma

LigandPNGBDBM65515(LAT-A | 76343-93-6 | LatA | Latrunculin A)
Affinity DataIC50: 70nMT: 2°CAssay Description:Saturated ACT1 wild type (WT) as well as engineered ACT1 R183K (R183K) and ACT1 R335K (R335K) cultures were adjusted to 10 OD600 and 3 uL of serial 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM36532(D158885)
Affinity DataIC50: 101nM EC50:  795nMAssay Description:In vitro biochemical assay using scavenger decapping enzyme (DcpS) as a target and cell based assay using SMN2 b-lactamase NSC-34 cell reporter gene.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2011
Entry Details Article
PubMed
TargetActin [R183K](Baker's yeast)
Novartis Pharma

LigandPNGBDBM65515(LAT-A | 76343-93-6 | LatA | Latrunculin A)
Affinity DataIC50: 110nMT: 2°CAssay Description:Saturated ACT1 wild type (WT) as well as engineered ACT1 R183K (R183K) and ACT1 R335K (R335K) cultures were adjusted to 10 OD600 and 3 uL of serial 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetActin(Baker's yeast)
Novartis Pharma

LigandPNGBDBM65506(SCHEMBL1889389 | CHEBI:80062 | Chivosazole F)
Affinity DataIC50: 140nMT: 2°CAssay Description:Saturated ACT1 wild type (WT) as well as engineered ACT1 R183K (R183K) and ACT1 R335K (R335K) cultures were adjusted to 10 OD600 and 3 uL of serial 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetActin [R335K](Baker's yeast)
Novartis Pharma

LigandPNGBDBM65506(SCHEMBL1889389 | CHEBI:80062 | Chivosazole F)
Affinity DataIC50: 270nMT: 2°CAssay Description:Saturated ACT1 wild type (WT) as well as engineered ACT1 R183K (R183K) and ACT1 R335K (R335K) cultures were adjusted to 10 OD600 and 3 uL of serial 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM36529(D156676)
Affinity DataIC50: 339nM EC50:  2.54E+3nMAssay Description:In vitro biochemical assay using scavenger decapping enzyme (DcpS) as a target and cell based assay using SMN2 b-lactamase NSC-34 cell reporter gene.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2011
Entry Details Article
PubMed
TargetActin [R183K](Baker's yeast)
Novartis Pharma

LigandPNGBDBM65506(SCHEMBL1889389 | CHEBI:80062 | Chivosazole F)
Affinity DataIC50: 380nMT: 2°CAssay Description:Saturated ACT1 wild type (WT) as well as engineered ACT1 R183K (R183K) and ACT1 R335K (R335K) cultures were adjusted to 10 OD600 and 3 uL of serial 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetActin [R183K](Baker's yeast)
Novartis Pharma

LigandPNGBDBM65516(CHEBI:84382 | CHEMBL2426321 | Chondramide C)
Affinity DataIC50: 1.19E+4nMT: 2°CAssay Description:Saturated ACT1 wild type (WT) as well as engineered ACT1 R183K (R183K) and ACT1 R335K (R335K) cultures were adjusted to 10 OD600 and 3 uL of serial 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetActin [R335K](Baker's yeast)
Novartis Pharma

LigandPNGBDBM65516(CHEBI:84382 | CHEMBL2426321 | Chondramide C)
Affinity DataIC50: 1.51E+4nMT: 2°CAssay Description:Saturated ACT1 wild type (WT) as well as engineered ACT1 R183K (R183K) and ACT1 R335K (R335K) cultures were adjusted to 10 OD600 and 3 uL of serial 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetActin(Baker's yeast)
Novartis Pharma

LigandPNGBDBM65516(CHEBI:84382 | CHEMBL2426321 | Chondramide C)
Affinity DataIC50: 1.67E+4nMT: 2°CAssay Description:Saturated ACT1 wild type (WT) as well as engineered ACT1 R183K (R183K) and ACT1 R335K (R335K) cultures were adjusted to 10 OD600 and 3 uL of serial 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed