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TargetPyruvate decarboxylase(Zymomonas mobilis subsp. mobilis (strain ATCC 3182...)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50589544(CHEMBL3559521)
Affinity DataKi:  0.0300nMAssay Description:Inhibition of Zymomonas mobilis pyruvate decarboxylase incubated for 3 mins using pyruvate as substrate in presence of TPP by spectrophotometric anal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50615069(CHEMBL5271689)
Affinity DataKi:  30nMAssay Description:Inhibition of porcine PDHc E1-subunit assessed as inhibition constant preincubated for 30 mins followed by pyruvate addition using 10 uM ThDP as subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50615071(CHEMBL5290932)
Affinity DataKi:  40nMAssay Description:Inhibition of porcine PDHc E1-subunit assessed as inhibition constant preincubated for 30 mins followed by pyruvate addition using 10 uM ThDP as subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50615070(CHEMBL5268763)
Affinity DataKi:  45nMAssay Description:Inhibition of porcine PDHc E1-subunit assessed as inhibition constant preincubated for 30 mins followed by pyruvate addition using 10 uM ThDP as subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPyruvate decarboxylase(Zymomonas mobilis subsp. mobilis (strain ATCC 3182...)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50589543(CHEMBL4277786)
Affinity DataKi:  3.00E+5nMAssay Description:Inhibition of Zymomonas mobilis pyruvate decarboxylase incubated for 3 mins using pyruvate as substrate in presence of TPP by spectrophotometric anal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPantothenate kinase 1, putative(Plasmodium falciparum (isolate 3D7))
The Australian National University

Curated by ChEMBL
LigandPNGBDBM50285608(CHEMBL4167606)
Affinity DataIC50:  140nMAssay Description:Inhibition of pantothenate kinase in Plasmodium falciparum 3D7 trophozoites using [14C]pantothenate as substrate after 15 mins by TopCount scintillat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50615069(CHEMBL5271689)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of porcine PDHc E1-subunit assessed as DCPIP reduction preincubated for 30 mins followed by pyruvate addition using 10 uM ThDP as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50615071(CHEMBL5290932)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of porcine PDHc E1-subunit assessed as DCPIP reduction preincubated for 30 mins followed by pyruvate addition using 10 uM ThDP as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50615070(CHEMBL5268763)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of porcine PDHc E1-subunit assessed as DCPIP reduction preincubated for 30 mins followed by pyruvate addition using 10 uM ThDP as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPantothenate kinase 1, putative(Plasmodium falciparum (isolate 3D7))
The Australian National University

Curated by ChEMBL
LigandPNGBDBM50285609(CHEMBL4164243)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of pantothenate kinase in Plasmodium falciparum 3D7 trophozoites using [14C]pantothenate as substrate after 15 mins by TopCount scintillat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed