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TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50559449(CHEMBL4779950)
Affinity DataEC50:  120nMAssay Description:Agonist activity at rat GPR119 expressed in CHO cells co-expressing cyclic AMP response element incubated for 2 hrs by steady-glo luciferase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50559449(CHEMBL4779950)
Affinity DataEC50:  19nMAssay Description:Agonist activity at GPR119 in glucose-induced mouse L cells assessed as induction of GLP-1 secretion after 2 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Targetglucose-dependent insulinotropic receptor(Golden hamster)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50559449(CHEMBL4779950)
Affinity DataEC50:  25nMAssay Description:Agonist activity at GPR119 in glucose-induced golden hamster HIT-T15 cells assessed as increase in insulin secretion after 2 hrs by A1phaLISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50559450(CHEMBL4780567)
Affinity DataEC50:  48nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing cyclic AMP response element incubated for 2 hrs by steady-glo luciferase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50559451(CHEMBL4798241)
Affinity DataEC50:  15nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing cyclic AMP response element incubated for 2 hrs by steady-glo luciferase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50559452(CHEMBL4746627)
Affinity DataEC50:  36nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing cyclic AMP response element incubated for 2 hrs by steady-glo luciferase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50559453(CHEMBL4760572)
Affinity DataEC50:  9.70nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing cyclic AMP response element incubated for 2 hrs by steady-glo luciferase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50559454(CHEMBL4763323)
Affinity DataEC50:  24nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing cyclic AMP response element incubated for 2 hrs by steady-glo luciferase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50559455(CHEMBL4755582)
Affinity DataEC50:  75nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing cyclic AMP response element incubated for 2 hrs by steady-glo luciferase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50559456(CHEMBL4759952)
Affinity DataEC50:  17nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing cyclic AMP response element incubated for 2 hrs by steady-glo luciferase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50559457(CHEMBL4780236)
Affinity DataEC50:  89nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing cyclic AMP response element incubated for 2 hrs by steady-glo luciferase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50559458(CHEMBL4754973)
Affinity DataEC50:  90nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing cyclic AMP response element incubated for 2 hrs by steady-glo luciferase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50559459(CHEMBL4739871)
Affinity DataEC50:  25nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing cyclic AMP response element incubated for 2 hrs by steady-glo luciferase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50559449(CHEMBL4779950)
Affinity DataEC50:  16nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing cyclic AMP response element incubated for 2 hrs by steady-glo luciferase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50446699(CHEMBL3112602)
Affinity DataEC50:  3.90nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing cyclic AMP response element incubated for 2 hrs by steady-glo luciferase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50446691(CHEMBL3113623)
Affinity DataEC50:  7.70nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing cyclic AMP response element incubated for 2 hrs by steady-glo luciferase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50446696(CHEMBL3113840)
Affinity DataEC50:  17nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing cyclic AMP response element incubated for 2 hrs by steady-glo luciferase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50559460(CHEMBL4778132)
Affinity DataEC50:  3.20nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing cyclic AMP response element incubated for 2 hrs by steady-glo luciferase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50559461(CHEMBL4789349)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing cyclic AMP response element incubated for 2 hrs by steady-glo luciferase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50559462(CHEMBL4752544)
Affinity DataEC50:  41nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing cyclic AMP response element incubated for 2 hrs by steady-glo luciferase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50559463(CHEMBL4790055)
Affinity DataEC50:  48nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing cyclic AMP response element incubated for 2 hrs by steady-glo luciferase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50559464(CHEMBL4757058)
Affinity DataEC50:  14nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing cyclic AMP response element incubated for 2 hrs by steady-glo luciferase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50559464(CHEMBL4757058)
Affinity DataEC50:  14nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing cyclic AMP response element incubated for 2 hrs by steady-glo luciferase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50559464(CHEMBL4757058)
Affinity DataEC50:  57nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing cyclic AMP response element incubated for 2 hrs by steady-glo luciferase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50559465(CHEMBL4788517)
Affinity DataEC50:  33nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing cyclic AMP response element incubated for 2 hrs by steady-glo luciferase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50559466(CHEMBL4796498)
Affinity DataEC50:  17nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing cyclic AMP response element incubated for 2 hrs by steady-glo luciferase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50446696(CHEMBL3113840)
Affinity DataEC50:  17nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing cyclic AMP response element-luciferase reporter gene incubated for 2 hrs by ste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50559449(CHEMBL4779950)
Affinity DataEC50:  16nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing cyclic AMP response element-luciferase reporter gene incubated for 2 hrs by ste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50568079(CHEMBL4870635)
Affinity DataEC50:  4.60nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing cyclic AMP response element-luciferase reporter gene incubated for 2 hrs by ste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50446714(CHEMBL3113626)
Affinity DataEC50:  68nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing cyclic AMP response element-luciferase reporter gene incubated for 2 hrs by ste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50446711(CHEMBL3113629)
Affinity DataEC50:  8.40nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing cyclic AMP response element-luciferase reporter gene incubated for 2 hrs by ste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50568080(CHEMBL4856239)
Affinity DataEC50:  300nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing cyclic AMP response element-luciferase reporter gene incubated for 2 hrs by ste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50568081(CHEMBL4871114)
Affinity DataEC50:  21nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing cyclic AMP response element-luciferase reporter gene incubated for 2 hrs by ste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50568082(CHEMBL4861760)
Affinity DataEC50:  14nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing cyclic AMP response element-luciferase reporter gene incubated for 2 hrs by ste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50568083(CHEMBL4877468)
Affinity DataEC50:  18nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing cyclic AMP response element-luciferase reporter gene incubated for 2 hrs by ste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50568084(CHEMBL4858330)
Affinity DataEC50:  51nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing cyclic AMP response element-luciferase reporter gene incubated for 2 hrs by ste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50568085(CHEMBL4873459)
Affinity DataEC50:  29nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing cyclic AMP response element-luciferase reporter gene incubated for 2 hrs by ste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50568086(CHEMBL4875358)
Affinity DataEC50:  2.5nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing cyclic AMP response element-luciferase reporter gene incubated for 2 hrs by ste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50568087(CHEMBL4876465)
Affinity DataEC50:  43nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing cyclic AMP response element-luciferase reporter gene incubated for 2 hrs by ste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50568088(CHEMBL4853684)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing cyclic AMP response element-luciferase reporter gene incubated for 2 hrs by ste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50568089(CHEMBL4855738)
Affinity DataEC50:  3.60nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing cyclic AMP response element-luciferase reporter gene incubated for 2 hrs by ste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50568090(CHEMBL4846489)
Affinity DataEC50:  270nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing cyclic AMP response element-luciferase reporter gene incubated for 2 hrs by ste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50568091(CHEMBL4851910)
Affinity DataEC50:  7.10E+3nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing cyclic AMP response element-luciferase reporter gene incubated for 2 hrs by ste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50568092(CHEMBL4857801)
Affinity DataEC50:  960nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing cyclic AMP response element-luciferase reporter gene incubated for 2 hrs by ste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50568093(CHEMBL4851479)
Affinity DataEC50:  2.70nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing cyclic AMP response element-luciferase reporter gene incubated for 2 hrs by ste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50568094(CHEMBL4846307)
Affinity DataEC50:  5.40nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing cyclic AMP response element-luciferase reporter gene incubated for 2 hrs by ste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50568095(CHEMBL4869157)
Affinity DataEC50:  2.90nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing cyclic AMP response element-luciferase reporter gene incubated for 2 hrs by ste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50568079(CHEMBL4870635)
Affinity DataEC50:  24nMAssay Description:Agonist activity at rat GPR119 expressed in CHO cells co-expressing cyclic AMP response element-luciferase reporter gene incubated for 2 hrs by stead...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50568079(CHEMBL4870635)
Affinity DataEC50:  4.80nMAssay Description:Agonist activity at rat GPR119 in golden hamster HIT-T15 cells assessed as induction of glucose-induced insulin secretion after 2 hrs by A1phaLISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50568079(CHEMBL4870635)
Affinity DataEC50:  3.80nMAssay Description:Agonist activity at rat GPR119 in GLUTag cells assessed as induction of GLP-1 secretion after 2 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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