Report error Found 18704 with Last Name = 'scozzafava' and Initial = 'a'
TargetCarbonic anhydrase 5A, mitochondrial(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr
Curated by ChEMBL
Istituto Di Biostrutture E Bioimmagini-Cnr
Curated by ChEMBL
Affinity DataKd: 20.6nMAssay Description:Inhibition of human carbonic anhydrase 5AMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 5A, mitochondrial(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr
Curated by ChEMBL
Istituto Di Biostrutture E Bioimmagini-Cnr
Curated by ChEMBL
Affinity DataKd: 25.4nMAssay Description:Inhibition of human carbonic anhydrase 5AMore data for this Ligand-Target Pair
Affinity DataKd: 47.6nMAssay Description:Inhibition of human carbonic anhydrase 2More data for this Ligand-Target Pair
Affinity DataKd: 13.8nMAssay Description:Inhibition of human carbonic anhydrase 2More data for this Ligand-Target Pair
Affinity DataIC50: 4.80nMAssay Description:Inhibition of human recombinant MMP9 expressed in mouse myeloma cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibitory activity of compound against human carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataIC50: 8.90nMAssay Description:Inhibition of human carbonic anhydrase 2More data for this Ligand-Target Pair
TargetCarbonic anhydrase 3(Human)
University of Tampere and Tampere University Hospital
Curated by ChEMBL
University of Tampere and Tampere University Hospital
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human carbonic anhydrase 3 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibitory activity of compound against human carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibitory activity of compound against human carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibitory activity of compound against human carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibitory activity of compound against human carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMpH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataIC50: 16.2nMAssay Description:Inhibition of human carbonic anhydrase 2 in presence of 0.01 mM beta-mercaptoethanolMore data for this Ligand-Target Pair
Affinity DataIC50: 16.2nMAssay Description:Inhibition of human carbonic anhydrase 2 in presence of 0.01 mM tris-(carboxyethyl)-phosphineMore data for this Ligand-Target Pair
Affinity DataIC50: 18.5nMAssay Description:Inhibition of human carbonic anhydrase 2 in presence of 0.01 mM threitolMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMpH: 7.4 T: 2°CAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of human carbonic anhydrase 9More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibitory activity of compound against human carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant MMP2 expressed in mouse myeloma cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMpH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of human carbonic anhydrase 2 assessed as 4-nitrophenyl acetate hydrolysisMore data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibitory activity of compound against human carbonic anhydrase IMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of human carbonic anhydrase 9 catalytic domainMore data for this Ligand-Target Pair
Affinity DataIC50: 34.3nMAssay Description:Inhibition of human carbonic anhydrase 2 in presence of 0.05 mM tris-(carboxyethyl)-phosphineMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of human carbonic anhydrase 2 in presence of 0.05 mM threitolMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibitory activity of compound against bovine carbonic anhydrase IVMore data for this Ligand-Target Pair
Affinity DataIC50: 36.2nMAssay Description:Inhibition of human carbonic anhydrase 9 in presence of 0.01 mM tris-(carboxyethyl)-phosphineMore data for this Ligand-Target Pair
Affinity DataIC50: 36.7nMAssay Description:Inhibition of human carbonic anhydrase 9 in presence of 0.01 mM threitolMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibitory activity of compound against human carbonic anhydrase IMore data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Inhibitory activity of compound against human carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibitory activity of compound against human carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataIC50: 42.1nMAssay Description:Inhibition of human carbonic anhydrase 9 in presence of 0.01 mM beta-mercaptoethanolMore data for this Ligand-Target Pair
Affinity DataIC50: 43nMpH: 7.4 T: 2°CAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Inhibitory activity of compound against human carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataIC50: 44.3nMAssay Description:Inhibition of human carbonic anhydrase 9 catalytic domain in presence of 0.01 mM beta-mercaptoethanolMore data for this Ligand-Target Pair
Affinity DataIC50: 47.6nMAssay Description:Inhibition of human carbonic anhydrase 2 in presence of 0.10 mM tris-(carboxyethyl)-phosphineMore data for this Ligand-Target Pair
Affinity DataIC50: 48.1nMAssay Description:Inhibition of human carbonic anhydrase 2 in presence of 0.25 mM tris-(carboxyethyl)-phosphineMore data for this Ligand-Target Pair
Affinity DataIC50: 48.3nMAssay Description:Inhibition of human carbonic anhydrase 2 in presence of 1.00 mM tris-(carboxyethyl)-phosphineMore data for this Ligand-Target Pair
Affinity DataIC50: 48.7nMAssay Description:Inhibition of human carbonic anhydrase 9 in presence of 0.05 mM tris-(carboxyethyl)-phosphineMore data for this Ligand-Target Pair
Affinity DataIC50: 48.9nMAssay Description:Inhibition of human carbonic anhydrase 2 in presence of 0.05 mM beta-mercaptoethanolMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibitory activity of compound against human carbonic anhydrase IMore data for this Ligand-Target Pair
Affinity DataIC50: 52.5nMAssay Description:Inhibition of human carbonic anhydrase 9 in presence of 0.05 mM threitolMore data for this Ligand-Target Pair
Affinity DataIC50: 53.1nMAssay Description:Inhibition of human carbonic anhydrase 2 in presence of 0.10 mM beta-mercaptoethanolMore data for this Ligand-Target Pair
Affinity DataIC50: 53.4nMAssay Description:Inhibition of human carbonic anhydrase 9 in presence of 0.10 mM tris-(carboxyethyl)-phosphineMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Inhibition of human carbonic anhydrase 9 in presence of 0.05 mM beta-mercaptoethanolMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Inhibitory activity of compound against bovine carbonic anhydrase IVMore data for this Ligand-Target Pair
Affinity DataIC50: 56.5nMAssay Description:Inhibition of human carbonic anhydrase 2 in presence of 10 mM tris-(carboxyethyl)-phosphineMore data for this Ligand-Target Pair
Affinity DataIC50: 56.7nMAssay Description:Inhibition of human carbonic anhydrase 9 in presence of 0.10 mM threitolMore data for this Ligand-Target Pair
Affinity DataIC50: 59nMAssay Description:Inhibition of human carbonic anhydrase 2 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
