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Found 26 with Last Name = 'seoane' and Initial = 's'
TargetVitamin D3 receptor(Homo sapiens (Human))
University Of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50200182((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...)
Affinity DataIC50:  1.20nMAssay Description:Competitive binding affinity to His-tagged human VDR LBD (156 to 453 residues) expressed in Escherichia coli BL23 (DE3) cells in presence of 1,25D3 b...More data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetVitamin D3 receptor(Homo sapiens (Human))
University Of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50200182((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...)
Affinity DataIC50:  1.24nMAssay Description:Binding affinity to VDR assessed as inhibition of fluorescent ligand by fluorescence polarization competition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetVitamin D3 receptor(Homo sapiens (Human))
University Of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50200182((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...)
Affinity DataIC50:  1.30nMAssay Description:Displacement of fluormone from human full length VDR after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetVitamin D3 receptor(Homo sapiens (Human))
University Of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50455852(CHEMBL4209452)
Affinity DataIC50:  3.5nMAssay Description:Displacement of fluormone from human full length VDR after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
University Of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50455853(CHEMBL4202828)
Affinity DataIC50:  4.5nMAssay Description:Displacement of fluormone from human full length VDR after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
University Of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50455855(CHEMBL4202601)
Affinity DataIC50:  5.60nMAssay Description:Displacement of fluormone from human full length VDR after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
University Of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50455851(CHEMBL4203540)
Affinity DataIC50:  8.30nMAssay Description:Displacement of fluormone from human full length VDR after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
University Of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50455854(CHEMBL4203464)
Affinity DataIC50:  10nMAssay Description:Displacement of fluormone from human full length VDR after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
University Of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50589996(CHEMBL5182683)
Affinity DataIC50:  15.7nMAssay Description:Competitive binding affinity to His-tagged human VDR LBD (156 to 453 residues) expressed in Escherichia coli BL23 (DE3) cells in presence of 1,25D3 b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
University Of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50397221(CHEMBL2172537)
Affinity DataIC50:  15.7nMAssay Description:Binding affinity to VDR assessed as inhibition of fluorescent ligand by fluorescence polarization competition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
University Of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50397223(CHEMBL2172539)
Affinity DataIC50:  20.9nMAssay Description:Binding affinity to VDR assessed as inhibition of fluorescent ligand by fluorescence polarization competition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
University Of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50397222(CHEMBL2172538)
Affinity DataIC50:  27.3nMAssay Description:Binding affinity to VDR assessed as inhibition of fluorescent ligand by fluorescence polarization competition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
University Of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50589995(CHEMBL5175578)
Affinity DataIC50:  27.3nMAssay Description:Competitive binding affinity to His-tagged human VDR LBD (156 to 453 residues) expressed in Escherichia coli BL23 (DE3) cells in presence of 1,25D3 b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
University Of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50455853(CHEMBL4202828)
Affinity DataEC50:  5.60nMAssay Description:Agonist activity at VDR in human MCF7 cells assessed as increase in transcription of CYP24A1 gene after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
University Of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50455854(CHEMBL4203464)
Affinity DataEC50:  9nMAssay Description:Agonist activity at VDR in human MCF7 cells assessed as increase in transcription of CYP24A1 gene after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
University Of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50455852(CHEMBL4209452)
Affinity DataEC50:  29nMAssay Description:Agonist activity at VDR in human MCF7 cells assessed as increase in transcription of CYP24A1 gene after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
University Of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50455851(CHEMBL4203540)
Affinity DataEC50:  10nMAssay Description:Agonist activity at VDR in human MCF7 cells assessed as increase in transcription of CYP24A1 gene after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
University Of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50397223(CHEMBL2172539)
Affinity DataEC50:  8.19nMAssay Description:Agonist activity at VDR in human MCF7 cells assessed as transcription of CYP24A1 gene after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
University Of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50397222(CHEMBL2172538)
Affinity DataEC50:  9.04nMAssay Description:Agonist activity at VDR in human MCF7 cells assessed as transcription of CYP24A1 gene after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
University Of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50200182((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...)
Affinity DataEC50:  3.28nMAssay Description:Agonist activity at VDR in human MCF7 cells assessed as transcription of CYP24A1 gene after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
University Of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50200182((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...)
Affinity DataEC50:  3nMAssay Description:Induction of CYP24A1 (unknown orgin) transcriptional activity trasfected in human MCF7 cells incuabted for 48 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
University Of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50589995(CHEMBL5175578)
Affinity DataEC50:  5.60nMAssay Description:Induction of CYP24A1 (unknown orgin) transcriptional activity trasfected in human MCF7 cells incuabted for 48 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
University Of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50589996(CHEMBL5182683)
Affinity DataEC50:  3nMAssay Description:Induction of CYP24A1 (unknown orgin) transcriptional activity trasfected in human MCF7 cells incuabted for 48 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
University Of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50397221(CHEMBL2172537)
Affinity DataEC50:  5.74nMAssay Description:Agonist activity at VDR in human MCF7 cells assessed as transcription of CYP24A1 gene after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
University Of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50200182((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...)
Affinity DataEC50:  1.60nMAssay Description:Agonist activity at VDR in human MCF7 cells assessed as increase in transcription of CYP24A1 gene after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetVitamin D3 receptor(Homo sapiens (Human))
University Of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50455855(CHEMBL4202601)
Affinity DataEC50:  8.60nMAssay Description:Agonist activity at VDR in human MCF7 cells assessed as increase in transcription of CYP24A1 gene after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed