Compile Data Set for Download or QSAR
Found 863 with Last Name = 'shackleford' and Initial = 'dm'
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cytopia Research Pty Ltd

Curated by ChEMBL
LigandPNGBDBM50311010(CHEMBL1078889 | N-(4-{2-[4-(1,1-Dioxo-1lambda*6*-t...)
Affinity DataIC50:  2nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cytopia Research Pty Ltd

Curated by ChEMBL
LigandPNGBDBM50311001(2-methoxy-4-(2-(4-morpholinophenylamino)pyrimidin-...)
Affinity DataIC50:  3nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
Monash University

Curated by ChEMBL
LigandPNGBDBM308131(US9649309, Compound UNC2876A)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of MERTK (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate incubated for 180 mins in presence of ATP by microfluidic capillary...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cytopia Research Pty Ltd

Curated by ChEMBL
LigandPNGBDBM50311011(CHEMBL1079077 | N-(4-(2-(4-morpholinophenylamino)p...)
Affinity DataIC50:  4nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
Monash University

Curated by ChEMBL
LigandPNGBDBM50602486(CHEMBL5196154)
Affinity DataIC50:  4nMAssay Description:Inhibition of MERTK (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate incubated for 180 mins in presence of ATP by microfluidic capillary...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
Monash University

Curated by ChEMBL
LigandPNGBDBM50602485(CHEMBL5171919)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of MERTK (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate incubated for 180 mins in presence of ATP by microfluidic capillary...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50527224(CHEMBL4468833 | US10829446, Compound 48)
Affinity DataIC50:  5nMAssay Description:Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Cytopia Research Pty Ltd

Curated by ChEMBL
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)
Affinity DataIC50:  5nMAssay Description:Inhibition of GST-tagged JAK3 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50527244(CHEMBL4437798 | US10829446, Compound 105)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cytopia Research Pty Ltd

Curated by ChEMBL
LigandPNGBDBM50311012(CHEMBL1079078 | N-(4-(2-(4-(4-hydroxypiperidin-1-y...)
Affinity DataIC50:  6nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cytopia Research Pty Ltd

Curated by ChEMBL
LigandPNGBDBM50311002(CHEMBL1078275 | N-(4-(2-(3-(pyrrolidin-1-ylmethyl)...)
Affinity DataIC50:  6nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50527381(CHEMBL4466823 | US10829446, Compound 41)
Affinity DataIC50:  6nMAssay Description:Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50527355(CHEMBL4456585 | US10829446, Compound 46)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50527250(CHEMBL4475883 | US10829446, Compound 67)
Affinity DataIC50:  7nMAssay Description:Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cytopia Research Pty Ltd

Curated by ChEMBL
LigandPNGBDBM50311004(CHEMBL1078277 | N-(4-(2-(3-(morpholinomethyl)pheny...)
Affinity DataIC50:  8nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cytopia Research Pty Ltd

Curated by ChEMBL
LigandPNGBDBM50311022(CHEMBL1078005 | N-(cyanomethyl)-4-(5-methyl-2-(4-m...)
Affinity DataIC50:  8nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50527238(CHEMBL4539384 | US10829446, Compound 42)
Affinity DataIC50:  8nMAssay Description:Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Cytopia Research Pty Ltd

Curated by ChEMBL
LigandPNGBDBM50311019(CHEMBL1078364 | N-(cyanomethyl)-2-methoxy-4-(2-(4-...)
Affinity DataIC50:  9nMAssay Description:Inhibition of GST-tagged JAK3 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cytopia Research Pty Ltd

Curated by ChEMBL
LigandPNGBDBM50311006(CHEMBL1078689 | N-(4-(2-(4-(morpholinomethyl)pheny...)
Affinity DataIC50:  9nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50527245(CHEMBL4521125 | US10829446, Compound 89)
Affinity DataIC50:  9nMAssay Description:Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50527328(CHEMBL4441439 | US10829446, Compound 49)
Affinity DataIC50:  9nMAssay Description:Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50527225(CHEMBL4565790 | US10829446, Compound 101)
Affinity DataIC50:  9.40nMAssay Description:Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cytopia Research Pty Ltd

Curated by ChEMBL
LigandPNGBDBM50311016(2-cyano-N-(4-(2-(4-morpholinophenylamino)pyrimidin...)
Affinity DataIC50:  10nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50527243(CHEMBL4458272 | US10829446, Compound 153)
Affinity DataIC50:  11nMAssay Description:Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cytopia Research Pty Ltd

Curated by ChEMBL
LigandPNGBDBM50311003(CHEMBL1078276 | N-(4-(2-(4-(piperidin-1-ylmethyl)p...)
Affinity DataIC50:  11nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Cytopia Research Pty Ltd

Curated by ChEMBL
LigandPNGBDBM50311017(CHEMBL1078178 | Momelotinib | N-(cyanomethyl)-4-(2...)
Affinity DataIC50:  11nMAssay Description:Inhibition of GST-tagged JAK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cytopia Research Pty Ltd

Curated by ChEMBL
LigandPNGBDBM50311005(CHEMBL1078688 | N-(4-(2-(3-((4-hydroxypiperidin-1-...)
Affinity DataIC50:  12nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50527263(CHEMBL4465716 | US10829446, Compound 63)
Affinity DataIC50:  13nMAssay Description:Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50527246(CHEMBL4445473 | US10829446, Compound 84)
Affinity DataIC50:  13nMAssay Description:Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM151585(US11739089, Compound Ketoconazole | US8987315, Ket...)
Affinity DataIC50:  13nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as testosterone 6beta-hydroxylation after 4 to 40 mins in presence of NADPH by LCMS analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cytopia Research Pty Ltd

Curated by ChEMBL
LigandPNGBDBM50311008(CHEMBL1078866 | N-(4-(2-(3-((4-methylpiperazin-1-y...)
Affinity DataIC50:  14nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50527235(CHEMBL4516984 | US10829446, Compound 52)
Affinity DataIC50:  14nMAssay Description:Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50527240(CHEMBL4541948 | US10829446, Compound 124)
Affinity DataIC50:  14nMAssay Description:Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50527232(CHEMBL4436877 | US10829446, Compound 78)
Affinity DataIC50:  14nMAssay Description:Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50527366(CHEMBL4449163 | US10829446, Compound 139)
Affinity DataIC50:  15nMAssay Description:Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cytopia Research Pty Ltd

Curated by ChEMBL
LigandPNGBDBM50311000(4-(4-amino-3-methoxyphenyl)-N-(4-morpholinophenyl)...)
Affinity DataIC50:  16nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50527382(CHEMBL4518462 | US10829446, Compound 145)
Affinity DataIC50:  16nMAssay Description:Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50527313(CHEMBL4446917 | US10829446, Compound 137)
Affinity DataIC50:  16nMAssay Description:Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cytopia Research Pty Ltd

Curated by ChEMBL
LigandPNGBDBM50311007(CHEMBL1078767 | N-(4-(2-(4-((4-hydroxypiperidin-1-...)
Affinity DataIC50:  16nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50527302(CHEMBL4573736 | US10829446, Compound 146)
Affinity DataIC50:  17nMAssay Description:Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50527277(CHEMBL4593500)
Affinity DataIC50:  17nMAssay Description:Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
University of Washington

Curated by ChEMBL
LigandPNGBDBM50018011(Aubagio | CHEBI:68540 | HMR-1726 | TERIFLUNOMIDE)
Affinity DataIC50:  17nMAssay Description:Inhibition of C-terminal His6-tagged rat DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assayMore data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50527251(CHEMBL4588945 | US10829446, Compound 66)
Affinity DataIC50:  18nMAssay Description:Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50527346(CHEMBL4566403 | US10829446, Compound 88)
Affinity DataIC50:  18nMAssay Description:Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cytopia Research Pty Ltd

Curated by ChEMBL
LigandPNGBDBM50311009(CHEMBL1078971 | N-(4-(2-(4-((4-methylpiperazin-1-y...)
Affinity DataIC50:  18nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cytopia Research Pty Ltd

Curated by ChEMBL
LigandPNGBDBM50311017(CHEMBL1078178 | Momelotinib | N-(cyanomethyl)-4-(2...)
Affinity DataIC50:  18nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50527365(CHEMBL4455027 | US10829446, Compound 91)
Affinity DataIC50:  20nMAssay Description:Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50527358(CHEMBL4572653 | US10829446, Compound 135)
Affinity DataIC50:  20nMAssay Description:Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM151585(US11739089, Compound Ketoconazole | US8987315, Ket...)
Affinity DataIC50:  22nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as midazolam 1'-hydroxylation after 4 to 40 mins in presence of NADPH by LCMS analysisMore data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50527221(CHEMBL4464911 | US10829446, Compound 64)
Affinity DataIC50:  23nMAssay Description:Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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