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TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50324667(TBC-1269 | 1,6-bis[3-(3-carboxymethylphenyl)-4-(2-...)
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of P-selectin in human HL-60 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201966(2-(benzo[b]thiophen-3-ylmethyl)-3-hydroxy-7,8,9,10...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201959(2-(2-chlorobenzyl)-3-hydroxy-7,8,9,10-tetrahydrobe...)
Affinity DataIC50: 1.23E+5nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201984(2-(4-chlorobenzyl)-3-hydroxy-7,8,9,10-tetrahydrobe...)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201978(2-(4-chlorophenylamino)-3-hydroxy-8-(trifluorometh...)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201983(2-(3-chlorobenzyl)-3-hydroxy-7,8,9,10-tetrahydrobe...)
Affinity DataIC50: 1.38E+5nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin glycoprotein ligand 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201984(2-(4-chlorobenzyl)-3-hydroxy-7,8,9,10-tetrahydrobe...)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of recombinant PSGL-1 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201967(2-(4-chlorobenzyl)-8-(fur-3-yl)-3-hydroxyquinoline...)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201973(2-((5-chloro-1H-indol-3-yl)methyl)-3-hydroxy-7,8,9...)
Affinity DataIC50: 1.75E+5nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201976(2-(4-chlorobenzyl)-3-(thiophene-2-carbonyloxy)-7,8...)
Affinity DataIC50: 1.75E+5nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin glycoprotein ligand 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50324665(3-Hydroxy-2-(1-phenylethyl)-7,8,9,10-tetrahydroben...)
Affinity DataIC50: 1.75E+5nMAssay Description:Inhibition of recombinant PSGL-1 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201958(2-((5-bromo-1H-indol-3-yl)methyl)-3-hydroxy-7,8,9,...)
Affinity DataIC50: 1.75E+5nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201991(2-(4-chlorobenzyl)-3-(cyclohexanecarbonyloxy)-7,8,...)
Affinity DataIC50: 1.75E+5nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201998(3-(benzoyloxy)-2-(4-chlorobenzyl)-7,8,9,10-tetrahy...)
Affinity DataIC50: 1.90E+5nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201965(3-hydroxy-2-((5-methyl-1H-indol-3-yl)methyl)-7,8,9...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201989(3-hydroxy-2-(5-methylthiophen-2-yl)-7,8,9,10-tetra...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201974(2-(4-chlorobenzyl)-3-hydroxy-8-phenylquinoline-4-c...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201993(2-(4-chlorobenzyl)-3-hydroxy-8-(thien-3-yl)quinoli...)
Affinity DataIC50: 2.25E+5nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201995(3-hydroxy-2-(1H-indol-3-yl)-7,8,9,10-tetrahydroben...)
Affinity DataIC50: 2.25E+5nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201955(2-(benzofuran-3-ylmethyl)-3-hydroxy-7,8,9,10-tetra...)
Affinity DataIC50: 2.25E+5nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201988(2-((1H-indol-3-yl)methyl)-3-hydroxy-7,8,9,10-tetra...)
Affinity DataIC50: 2.25E+5nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201972(2-(4-chlorobenzyl)-3-hydroxy-8-isopropylquinoline-...)
Affinity DataIC50: 2.25E+5nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin glycoprotein ligand 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50324664(3-Hydroxy-2-(1-phenylcyclopropyl)-7,8,9,10-tetrahy...)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of recombinant PSGL-1 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201969(2-((5-chloro-1H-indol-3-yl)methyl)-3-hydroxy-8-(tr...)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201954(2-(4-chlorobenzyl)-8-ethyl-3-hydroxyquinoline-4-ca...)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201953(2-(4-chlorobenzyl)-3-(isobutoxycarbonyloxy)-7,8,9,...)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201960(3-hydroxy-2-((2-methyl-1H-indol-3-yl)methyl)-7,8,9...)
Affinity DataIC50: 2.70E+5nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201979(8-(sec-butyl)-2-(4-chlorobenzyl)-3-hydroxyquinolin...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201962(2-(4-chlorobenzyl)-3-hydroxy-8-(trifluoromethyl)qu...)
Affinity DataIC50: 3.25E+5nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201970(3-hydroxy-2-(1H-indol-3-ylmethyl)-8-(3-thienyl)qui...)
Affinity DataIC50: 3.80E+5nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201985(3-(benzyloxy)-2-(4-chlorobenzyl)-7,8,9,10-tetrahyd...)
Affinity DataIC50: 3.90E+5nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201997(2-(4-chlorobenzyl)-3-(methoxycarbonyloxy)-7,8,9,10...)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201964(3-hydroxy-2-((5-methoxy-1H-indol-3-yl)methyl)-7,8,...)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201977(2-benzyl-3-hydroxy-7,8,9,10-tetrahydrobenzo[h]quin...)
Affinity DataIC50: 4.13E+5nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin glycoprotein ligand 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201977(2-benzyl-3-hydroxy-7,8,9,10-tetrahydrobenzo[h]quin...)
Affinity DataIC50: 4.13E+5nMAssay Description:Inhibition of recombinant PSGL-1 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201987(3-hydroxy-2-(thiophen-2-ylmethyl)-7,8,9,10-tetrahy...)
Affinity DataIC50: 4.13E+5nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201956(3-hydroxy-2-(1H-indol-3-ylmethyl)-8-isopropylquino...)
Affinity DataIC50: 4.15E+5nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201994(8-bromo-2-(4-chlorobenzyl)-3-hydroxyquinoline-4-ca...)
Affinity DataIC50: 4.25E+5nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201951(3-hydroxy-2-phenethyl-7,8,9,10-tetrahydrobenzo[h]q...)
Affinity DataIC50: 4.50E+5nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201963(3-hydroxy-2-(thiophen-3-ylmethyl)-7,8,9,10-tetrahy...)
Affinity DataIC50: 4.75E+5nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201990(2-(4-chlorobenzyl)-3-hydroxy-9-(isopropylsulfonyl)...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201961(2-(4-cyanobenzyl)-3-hydroxy-7,8,9,10-tetrahydroben...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201982(3-acetoxy-2-(4-chlorobenzyl)-7,8,9,10-tetrahydrobe...)
Affinity DataIC50: 5.45E+5nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201968(2-(4-chlorobenzyl)-3-hydroxy-8-(trifluoromethoxy)q...)
Affinity DataIC50: 5.50E+5nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201957(3-hydroxy-2-phenyl-7,8,9,10-tetrahydrobenzo[h]quin...)
Affinity DataIC50: 5.50E+5nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201981(8-(4-chlorobenzyl)-7-hydroxy-2,3-dihydro-1H-9-aza-...)
Affinity DataIC50: 5.80E+5nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201975(3-hydroxy-2-(4-(trifluoromethoxy)benzyl)-7,8,9,10-...)
Affinity DataIC50: 6.10E+5nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201980(2-(4-chlorobenzyl)-3-hydroxy-9-(methylsulfonyl)-7,...)
Affinity DataIC50: 6.25E+5nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201971(6-bromo-2-(4-chlorobenzyl)-3-hydroxyquinoline-4-ca...)
Affinity DataIC50: 6.50E+5nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201992(8-chloro-2-(4-chlorobenzyl)-3-hydroxyquinoline-4-c...)
Affinity DataIC50: 7.15E+5nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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