Compile Data Set for Download or QSAR
Found 7262 with Last Name = 'shen' and Initial = 'm'
TargetPhosphodiesterase(Macaca mulatta (Rhesus macaque))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM355246(US9815796, Example 337)
Affinity DataKi:  0.400nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM354912(1-Methylcyclopropanamine Oxalate | US9815796, Exam...)
Affinity DataKi:  0.450nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM355376(N-{(1R)-2,2-dimethyl-1-[4- (trifluoromethoxy)pheny...)
Affinity DataKi:  0.490nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM355552(N-{(1S)-1-[2-chloro-4- (trifluoromethyl)phenyl]-2-...)
Affinity DataKi:  0.5nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM355445(N-[(1R)-1-(4-cyclopropylphenyl)- 2,2-dimethylpropy...)
Affinity DataKi:  0.510nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM354913(2-Methyl-2-(1H-pyrazol-1-yl)propanimidamide acetat...)
Affinity DataKi:  0.520nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphodiesterase(Macaca mulatta (Rhesus macaque))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM354912(1-Methylcyclopropanamine Oxalate | US9815796, Exam...)
Affinity DataKi:  0.540nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphodiesterase(Macaca mulatta (Rhesus macaque))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM354913(2-Methyl-2-(1H-pyrazol-1-yl)propanimidamide acetat...)
Affinity DataKi:  0.560nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM355364(N-{(1R)-2,2-dimethyl-1-[4- (trifluoromethyl)phenyl...)
Affinity DataKi:  0.600nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphodiesterase(Macaca mulatta (Rhesus macaque))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM355373(N-{(1R)-1-[3-fluoro-4- (trifluoromethoxy)phenyl]-2...)
Affinity DataKi:  0.600nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM355374(N-[(1R)-2,2-dimethyl-1-{4- [(trifluoromethyl)sulfa...)
Affinity DataKi:  0.620nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphodiesterase(Macaca mulatta (Rhesus macaque))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM355376(N-{(1R)-2,2-dimethyl-1-[4- (trifluoromethoxy)pheny...)
Affinity DataKi:  0.620nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphodiesterase(Macaca mulatta (Rhesus macaque))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM355374(N-[(1R)-2,2-dimethyl-1-{4- [(trifluoromethyl)sulfa...)
Affinity DataKi:  0.620nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM355366(N-{(1R)-2,2-dimethyl-1-[4- (trifluoromethyl)phenyl...)
Affinity DataKi:  0.640nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphodiesterase(Macaca mulatta (Rhesus macaque))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM355171(2-cyclopropyl-N-{(1R)-2,2-dimethyl- 1-[4-(trifluor...)
Affinity DataKi:  0.650nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphodiesterase(Macaca mulatta (Rhesus macaque))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM355366(N-{(1R)-2,2-dimethyl-1-[4- (trifluoromethyl)phenyl...)
Affinity DataKi:  0.680nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphodiesterase(Macaca mulatta (Rhesus macaque))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM355364(N-{(1R)-2,2-dimethyl-1-[4- (trifluoromethyl)phenyl...)
Affinity DataKi:  0.680nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM355373(N-{(1R)-1-[3-fluoro-4- (trifluoromethoxy)phenyl]-2...)
Affinity DataKi:  0.690nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphodiesterase(Macaca mulatta (Rhesus macaque))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM355417(2-(3-fluoro-4-methoxybenzyl)-N- {(1R)-1-[3-fluoro-...)
Affinity DataKi:  0.770nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM355344(2-cyclopropyl-N-[(1R)-1-(4- cyclopropyl-3-fluoroph...)
Affinity DataKi:  0.780nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM355375(N-{(1R)-1-[3-fluoro-4- (trifluoromethyl)phenyl]-2,...)
Affinity DataKi:  0.790nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM355171(2-cyclopropyl-N-{(1R)-2,2-dimethyl- 1-[4-(trifluor...)
Affinity DataKi:  0.790nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM355417(2-(3-fluoro-4-methoxybenzyl)-N- {(1R)-1-[3-fluoro-...)
Affinity DataKi:  0.800nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM355415(2-(3-fluoro-4-methoxybenzyl)-N- {(1R)-1-[3-fluoro-...)
Affinity DataKi:  0.800nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM355372(2-cyclopropyl-N-{(1R)-2,2- dimethyl-1-[4- (trifluo...)
Affinity DataKi:  0.840nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphodiesterase(Macaca mulatta (Rhesus macaque))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM355171(2-cyclopropyl-N-{(1R)-2,2-dimethyl- 1-[4-(trifluor...)
Affinity DataKi:  0.850nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphodiesterase(Macaca mulatta (Rhesus macaque))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM355375(N-{(1R)-1-[3-fluoro-4- (trifluoromethyl)phenyl]-2,...)
Affinity DataKi:  0.850nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM355382(N-{(1R)-1-[3-fluoro-4- (trifluoromethoxy)phenyl]-2...)
Affinity DataKi:  0.860nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphodiesterase(Macaca mulatta (Rhesus macaque))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM355418(N-{(1R)-2,2-dimethyl-1-[4- (trifluoromethoxy)pheny...)
Affinity DataKi:  0.880nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM355378(2-(4-methoxybenzyl)-N-[(1R)-2- methyl-1-{4- [(trif...)
Affinity DataKi:  0.910nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphodiesterase(Macaca mulatta (Rhesus macaque))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM355415(2-(3-fluoro-4-methoxybenzyl)-N- {(1R)-1-[3-fluoro-...)
Affinity DataKi:  0.920nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphodiesterase(Macaca mulatta (Rhesus macaque))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM355378(2-(4-methoxybenzyl)-N-[(1R)-2- methyl-1-{4- [(trif...)
Affinity DataKi:  0.960nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM355418(N-{(1R)-2,2-dimethyl-1-[4- (trifluoromethoxy)pheny...)
Affinity DataKi:  0.990nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphodiesterase(Macaca mulatta (Rhesus macaque))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM355153(2-cyclopropyl-N-[(1R)-1-{3-fluoro-4- [(trifluorome...)
Affinity DataKi:  0.990nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphodiesterase(Macaca mulatta (Rhesus macaque))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM355169(N-[(1R)-1-{3-fluoro-4- [(trifluoromethyl)sulfanyl]...)
Affinity DataKi:  1nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphodiesterase(Macaca mulatta (Rhesus macaque))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM355348(2-cyclopropyl-N-[(1R)-2,2-dimethyl- 1-{4- [(triflu...)
Affinity DataKi:  1nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM355424(2-(3-fluoro-4-methoxybenzyl)-N- {(1R)-1-[3-fluoro-...)
Affinity DataKi:  1nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM355416(N-[(1R)-2,2-dimethyl-1-{4- [(trifluoromethyl)sulfa...)
Affinity DataKi:  1nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphodiesterase(Macaca mulatta (Rhesus macaque))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM355416(N-[(1R)-2,2-dimethyl-1-{4- [(trifluoromethyl)sulfa...)
Affinity DataKi:  1.10nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphodiesterase(Macaca mulatta (Rhesus macaque))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM355382(N-{(1R)-1-[3-fluoro-4- (trifluoromethoxy)phenyl]-2...)
Affinity DataKi:  1.10nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphodiesterase(Macaca mulatta (Rhesus macaque))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM355424(2-(3-fluoro-4-methoxybenzyl)-N- {(1R)-1-[3-fluoro-...)
Affinity DataKi:  1.10nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM355437(2-(3-fluoro-4-methoxybenzyl)-N- {(1R)-1-[3-fluoro-...)
Affinity DataKi:  1.10nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphodiesterase(Macaca mulatta (Rhesus macaque))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM355344(2-cyclopropyl-N-[(1R)-1-(4- cyclopropyl-3-fluoroph...)
Affinity DataKi:  1.10nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM355246(US9815796, Example 337)
Affinity DataKi:  1.10nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM355037(2-cyclopropyl-N-{(1R)-1-[3-fluoro-4- (trifluoromet...)
Affinity DataKi:  1.20nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphodiesterase(Macaca mulatta (Rhesus macaque))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM355246(US9815796, Example 337)
Affinity DataKi:  1.20nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphodiesterase(Macaca mulatta (Rhesus macaque))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM355346(2-cyclopropyl-N-{(1R)-1-[3-fluoro-4- (trifluoromet...)
Affinity DataKi:  1.20nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThyrotropin-releasing hormone receptor(MOUSE)
Washington University

Curated by ChEMBL
LigandPNGBDBM50050531(1-[3-(1-methyl-4-imidazolyl)-2-[2-oxo-(5S)-dihydro...)
Affinity DataKi:  1.20nMAssay Description:Binding affinity against TRH-R receptor in AtT-20 mouse pituitary tumor cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM355454(N-{(1R)-1-[2-fluoro-4- (trifluoromethyl)phenyl]-2,...)
Affinity DataKi:  1.20nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphodiesterase(Macaca mulatta (Rhesus macaque))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM355372(2-cyclopropyl-N-{(1R)-2,2- dimethyl-1-[4- (trifluo...)
Affinity DataKi:  1.20nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Displayed 1 to 50 (of 7262 total ) | Next | Last >>
Jump to: