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TargetReplicase polyprotein 1ab(2019-nCoV)
Australian National University

Curated by ChEMBL
LigandPNGBDBM50567201(CHEMBL4875501)
Affinity DataKi:  5.70E+4nMAssay Description:Competitive inhibition of SARS CoV-2 main protease using varying concentrations of DABCYL-KTSAVLQ1SGFRKM-E(EDANS)-NH2 as substrate by Dixon plot anal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50457851(CHEMBL4205416)
Affinity DataIC50:  2nMAssay Description:Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50457853(CHEMBL4215340)
Affinity DataIC50:  4nMAssay Description:Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50457851(CHEMBL4205416)
Affinity DataIC50:  4nMAssay Description:Inhibition of PI4K3beta in human PBMC assessed as reduction in mitomycin-C treated human RPMI1788 cells-stimulated lymphocyte proliferation by measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50457886(CHEMBL4211696)
Affinity DataIC50:  4nMAssay Description:Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50457854(CHEMBL4206816)
Affinity DataIC50:  5nMAssay Description:Inhibition of PI4K3beta in human PBMC assessed as reduction in mitomycin-C treated human RPMI1788 cells-stimulated lymphocyte proliferation by measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50457855(CHEMBL4211181)
Affinity DataIC50:  5nMAssay Description:Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50457848(CHEMBL4215244)
Affinity DataIC50:  7nMAssay Description:Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50457867(CHEMBL4203566)
Affinity DataIC50:  7nMAssay Description:Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50457876(CHEMBL4209793)
Affinity DataIC50:  8nMAssay Description:Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50457853(CHEMBL4215340)
Affinity DataIC50:  8nMAssay Description:Inhibition of PI4K3beta in human PBMC assessed as reduction in mitomycin-C treated human RPMI1788 cells-stimulated lymphocyte proliferation by measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50457850(CHEMBL4203041)
Affinity DataIC50:  8nMAssay Description:Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50457868(CHEMBL4202450)
Affinity DataIC50:  8nMAssay Description:Inhibition of PI4K3beta in human PBMC assessed as reduction in mitomycin-C treated human RPMI1788 cells-stimulated lymphocyte proliferation by measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50005005(CHEMBL2397317)
Affinity DataIC50:  8nMAssay Description:Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50457860(CHEMBL4207851)
Affinity DataIC50:  9nMAssay Description:GRAC: human Y1 selective antagonistMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50457870(CHEMBL1652677)
Affinity DataIC50:  10nMAssay Description:Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50457871(CHEMBL4210308)
Affinity DataIC50:  11nMAssay Description:Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50457855(CHEMBL4211181)
Affinity DataIC50:  11nMAssay Description:Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50457848(CHEMBL4215244)
Affinity DataIC50:  13nMAssay Description:Inhibition of PI4K3beta in human PBMC assessed as reduction in mitomycin-C treated human RPMI1788 cells-stimulated lymphocyte proliferation by measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50457870(CHEMBL1652677)
Affinity DataIC50:  16nMAssay Description:Inhibition of PI4K3beta in human PBMC assessed as reduction in mitomycin-C treated human RPMI1788 cells-stimulated lymphocyte proliferation by measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50457862(CHEMBL4204100)
Affinity DataIC50:  18nMAssay Description:Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50457886(CHEMBL4211696)
Affinity DataIC50:  18nMAssay Description:Inhibition of PI4K3beta in human PBMC assessed as reduction in mitomycin-C treated human RPMI1788 cells-stimulated lymphocyte proliferation by measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50042924(CHEMBL1229535)
Affinity DataIC50:  19nMAssay Description:Inhibition of PI4K3beta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50457854(CHEMBL4206816)
Affinity DataIC50:  19nMAssay Description:Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50457866(CHEMBL4207928)
Affinity DataIC50:  20nMAssay Description:Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50457862(CHEMBL4204100)
Affinity DataIC50:  23nMAssay Description:Inhibition of PI4K3beta in human PBMC assessed as reduction in mitomycin-C treated human RPMI1788 cells-stimulated lymphocyte proliferation by measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50042924(CHEMBL1229535)
Affinity DataIC50:  28nMAssay Description:Inhibition of PI4K3beta in human PBMC assessed as reduction in mitomycin-C treated human RPMI1788 cells-stimulated lymphocyte proliferation by measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50457850(CHEMBL4203041)
Affinity DataIC50:  31nMAssay Description:Inhibition of PI4K3beta in human PBMC assessed as reduction in mitomycin-C treated human RPMI1788 cells-stimulated lymphocyte proliferation by measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50457871(CHEMBL4210308)
Affinity DataIC50:  32nMAssay Description:Inhibition of PI4K3beta in human PBMC assessed as reduction in mitomycin-C treated human RPMI1788 cells-stimulated lymphocyte proliferation by measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50457860(CHEMBL4207851)
Affinity DataIC50:  35nMAssay Description:Inhibition of PI4K3beta in human PBMC assessed as reduction in mitomycin-C treated human RPMI1788 cells-stimulated lymphocyte proliferation by measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50457855(CHEMBL4211181)
Affinity DataIC50:  37nMAssay Description:Inhibition of PI4K3beta in human PBMC assessed as reduction in mitomycin-C treated human RPMI1788 cells-stimulated lymphocyte proliferation by measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50457877(CHEMBL4215615)
Affinity DataIC50:  42nMAssay Description:Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50457867(CHEMBL4203566)
Affinity DataIC50:  47nMAssay Description:Inhibition of PI4K3beta in human PBMC assessed as reduction in mitomycin-C treated human RPMI1788 cells-stimulated lymphocyte proliferation by measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50457869(CHEMBL4217096)
Affinity DataIC50:  51nMAssay Description:Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50457876(CHEMBL4209793)
Affinity DataIC50:  53nMAssay Description:Inhibition of PI4K3beta in human PBMC assessed as reduction in mitomycin-C treated human RPMI1788 cells-stimulated lymphocyte proliferation by measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50457869(CHEMBL4217096)
Affinity DataIC50:  53nMAssay Description:Inhibition of PI4K3beta in human PBMC assessed as reduction in mitomycin-C treated human RPMI1788 cells-stimulated lymphocyte proliferation by measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50457866(CHEMBL4207928)
Affinity DataIC50:  60nMAssay Description:Inhibition of PI4K3beta in human PBMC assessed as reduction in mitomycin-C treated human RPMI1788 cells-stimulated lymphocyte proliferation by measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50457877(CHEMBL4215615)
Affinity DataIC50:  71nMAssay Description:Inhibition of PI4K3beta in human PBMC assessed as reduction in mitomycin-C treated human RPMI1788 cells-stimulated lymphocyte proliferation by measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50457852(CHEMBL4205444)
Affinity DataIC50:  85nMAssay Description:Inhibition of PI4K3beta in human PBMC assessed as reduction in mitomycin-C treated human RPMI1788 cells-stimulated lymphocyte proliferation by measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50457878(CHEMBL4209824)
Affinity DataIC50:  114nMAssay Description:Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50457856(CHEMBL4210332)
Affinity DataIC50:  115nMAssay Description:Inhibition of PI4K3beta in human PBMC assessed as reduction in mitomycin-C treated human RPMI1788 cells-stimulated lymphocyte proliferation by measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50457852(CHEMBL4205444)
Affinity DataIC50:  145nMAssay Description:GRAC: human Y1 selective antagonistMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50457878(CHEMBL4209824)
Affinity DataIC50:  150nMAssay Description:Inhibition of PI4K3beta in human PBMC assessed as reduction in mitomycin-C treated human RPMI1788 cells-stimulated lymphocyte proliferation by measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50457861(CHEMBL4216301)
Affinity DataIC50:  173nMAssay Description:Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50457861(CHEMBL4216301)
Affinity DataIC50:  195nMAssay Description:Inhibition of PI4K3beta in human PBMC assessed as reduction in mitomycin-C treated human RPMI1788 cells-stimulated lymphocyte proliferation by measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50457874(CHEMBL4210718)
Affinity DataIC50:  216nMAssay Description:Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50457864(CHEMBL4213363)
Affinity DataIC50:  275nMAssay Description:Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50457856(CHEMBL4210332)
Affinity DataIC50:  312nMAssay Description:Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50457882(CHEMBL4203671)
Affinity DataIC50:  316nMAssay Description:Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50457887(CHEMBL4214728)
Affinity DataIC50:  331nMAssay Description:Inhibition of PI4K3beta in human PBMC assessed as reduction in mitomycin-C treated human RPMI1788 cells-stimulated lymphocyte proliferation by measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

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