TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Guru Nanak Dev University
Curated by ChEMBL
Guru Nanak Dev University
Curated by ChEMBL
Affinity DataKi: 0.0417nMAssay Description:Mixed type inhibition of electric eel AChE assessed as inhibition constant using varying levels of acetylthiocholine as substrate by reciprocal Linew...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataKi: 0.0617nMAssay Description:Inhibition of human PDE4D2 expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit basedMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataKi: 0.120nMAssay Description:Inhibition of human PDE4D2 expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit basedMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataKi: 0.123nMAssay Description:Inhibition of human PDE4D2 expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit basedMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataKi: 0.155nMAssay Description:Inhibition of human PDE4D2 expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit basedMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataKi: 0.155nMAssay Description:Inhibition of human PDE4D2 expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit basedMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataKi: 0.162nMAssay Description:Inhibition of human PDE4D2 expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit basedMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataKi: 0.170nMAssay Description:Inhibition of human PDE4D2 expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit basedMore data for this Ligand-Target Pair
Affinity DataKi: 0.170nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptorMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataKi: 0.224nMAssay Description:Inhibition of human PDE4D2 expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit basedMore data for this Ligand-Target Pair
Affinity DataKi: 0.230nMAssay Description:Displacement of [125I]SI-Ang2 from AT1 receptor in Sprague-Dawley rat liver membraneMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataKi: 0.234nMAssay Description:Inhibition of human PDE4D2 expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit basedMore data for this Ligand-Target Pair
Affinity DataKi: 0.260nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptorMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataKi: 0.302nMAssay Description:Inhibition of human PDE4D2 expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit basedMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataKi: 0.316nMAssay Description:Inhibition of human PDE4D2 expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit basedMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataKi: 0.316nMAssay Description:Inhibition of human PDE4D2 expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit basedMore data for this Ligand-Target Pair
Affinity DataKi: 0.340nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.340nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.350nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptorMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataKi: 0.355nMAssay Description:Inhibition of human PDE4D2 expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit basedMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataKi: 0.389nMAssay Description:Inhibition of human PDE4D2 expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit basedMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Vrije Universiteit Amsterdam
Curated by ChEMBL
Vrije Universiteit Amsterdam
Curated by ChEMBL
Affinity DataKi: 0.398nMAssay Description:Inhibition of full length recombinant human PDE4B1 expressed in Sf21 insect cells using cAMP as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.460nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from rat cloned H3 receptorMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataKi: 0.513nMAssay Description:Inhibition of human PDE4D2 expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit basedMore data for this Ligand-Target Pair
Affinity DataKi: 0.530nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.530nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.540nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.560nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from rat cloned H3 receptorMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataKi: 0.562nMAssay Description:Inhibition of human PDE4D2 expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit basedMore data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [501-599,Q508K,L534I,L564I,C568A,C596A](Human immunodeficiency virus type 1)
University of Queensland
University of Queensland
Affinity DataKi: 0.600nM ΔG°: -54.8kJ/molepH: 6.5 T: 2°CAssay Description:he Ki values were determined using fluorogenic substrate, 2-(aminobenzoyl)-Thr-Ile-Nle-Phe(p-NO2)-Gln-ArgNH2. A standard curve relating changes in fl...More data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptorMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Vrije Universiteit Amsterdam
Curated by ChEMBL
Vrije Universiteit Amsterdam
Curated by ChEMBL
Affinity DataKi: 0.631nMAssay Description:Inhibition of full length recombinant human PDE4B1 expressed in Sf21 insect cells using cAMP as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.640nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from rat cloned H3 receptorMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataKi: 0.661nMAssay Description:Inhibition of human PDE4D2 expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit basedMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataKi: 0.676nMAssay Description:Inhibition of human PDE4D2 expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit basedMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataKi: 0.676nMAssay Description:Inhibition of human PDE4D2 expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit basedMore data for this Ligand-Target Pair
Affinity DataKi: 0.720nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from rat cloned H3 receptorMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataKi: 0.851nMAssay Description:Inhibition of human PDE4D2 expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit basedMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataKi: 0.871nMAssay Description:Inhibition of human PDE4D2 expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit basedMore data for this Ligand-Target Pair
Affinity DataKi: 0.890nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from rat cloned H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.970nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from rat cloned H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.01nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from rat cloned H3 receptorMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Inhibition of human PDE4D2 expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit basedMore data for this Ligand-Target Pair
Affinity DataKi: 1.29nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from rat cloned H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
