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TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50288211(CHEMBL87862 | Zwitterionic sulfobetaine derivative)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibitory activity against rat hepatic squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails Article

TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50288217(CHEMBL87659 | Zwitterionic sulfobetaine derivative)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibitory activity against rat hepatic squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails Article

TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50288206(CHEMBL87671 | Zwitterionic sulfobetaine derivative)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibitory activity against rat hepatic squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails Article

TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50288216(CHEMBL87977 | Zwitterionic sulfobetaine derivative)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibitory activity against rat hepatic squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails Article

TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50288205(CHEMBL86641 | Zwitterionic sulfobetaine derivative)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibitory activity against rat hepatic squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails Article

TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50288209(CHEMBL87515 | Zwitterionic sulfobetaine derivative)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibitory activity against rat hepatic squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails Article

TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50288207(CHEMBL87606 | Zwitterionic sulfobetaine derivative)
Affinity DataIC50:  6.00E+4nMAssay Description:Inhibitory activity against rat hepatic squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails Article

TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50288213(CHEMBL89502 | Zwitterionic sulfobetaine derivative)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibitory activity against rat hepatic squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails Article

TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50288208(CHEMBL87297 | Zwitterionic sulfobetaine derivative)
Affinity DataIC50:  2.00E+5nMAssay Description:Inhibitory activity against rat hepatic squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails Article

TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50288212(CHEMBL87864 | Zwitterionic sulfobetaine derivative)
Affinity DataIC50:  2.00E+5nMAssay Description:Inhibitory activity against rat hepatic squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails Article

TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50288214(CHEMBL87400 | Zwitterionic sulfobetaine derivative)
Affinity DataIC50:  2.00E+5nMAssay Description:Inhibitory activity against rat hepatic squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails Article

TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50288215(CHEMBL420240 | Zwitterionic sulfobetaine derivativ...)
Affinity DataIC50:  2.00E+5nMAssay Description:Inhibitory activity against rat hepatic squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails Article

TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50288210(CHEMBL89610 | Zwitterionic sulfobetaine derivative)
Affinity DataIC50:  2.00E+5nMAssay Description:Inhibitory activity against rat hepatic squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails Article

TargetOxysterols receptor LXR-alpha(Human)
Dartmouth College

LigandPNGBDBM20187((4R)-4-[(1S,2R,5S,10S,11S,14R,15R)-5-hydroxy-2,15-...)
Affinity DataEC50:  720nMpH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Dartmouth College

LigandPNGBDBM20188(22-[N-(2 -methylpropionyl)amino]-23,24-bisnorchol-...)
Affinity DatapH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Dartmouth College

LigandPNGBDBM20189(1-[(2S)-2-[(1S,2R,5S,10S,11S,14R,15S)-5-hydroxy-2,...)
Affinity DatapH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Dartmouth College

LigandPNGBDBM20190((4R)-4-[(1S,2R,5S,10S,11S,14R,15R)-5-hydroxy-2,15-...)
Affinity DataEC50:  3.00E+3nMpH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Dartmouth College

LigandPNGBDBM20191(cholenic acid methyl ester | methyl (4R)-4-[(1S,2R...)
Affinity DataEC50:  105nMpH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Dartmouth College

LigandPNGBDBM20192((1S,2R,5S,10S,11S,14R,15R)-2,15-dimethyl-14-[(2R)-...)
Affinity DatapH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Dartmouth College

LigandPNGBDBM20186((4R)-4-[(1S,2R,5S,10S,11S,14R,15R)-5-hydroxy-2,15-...)
Affinity DataEC50:  170nMpH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Dartmouth College

LigandPNGBDBM20185((6R)-6-[(1S,2R,5S,10S,11S,14R,15R)-5-hydroxy-2,15-...)
Affinity DataEC50:  180nMpH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Dartmouth College

LigandPNGBDBM20184((2R)-2-[(2R)-2-[(1S,2R,5S,10S,11S,14R,15R)-5-hydro...)
Affinity DatapH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Dartmouth College

LigandPNGBDBM20183((1S,2R,5S,10S,11S,14R,15R)-14-[(2R,6R)-7-hydroxy-6...)
Affinity DataEC50:  250nMpH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Dartmouth College

LigandPNGBDBM20182((1S,2R,5S,10S,11S,14R,15R)-14-[(2R)-6-hydroxy-6-me...)
Affinity DataEC50:  1.16E+3nMpH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Dartmouth College

LigandPNGBDBM20181((1S,2R,5S,10S,11S,14R,15R)-14-[(2R,5R)-5-hydroxy-6...)
Affinity DataEC50:  220nMpH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Dartmouth College

LigandPNGBDBM20180((1S,2R,5S,10S,11S,14R,15R)-14-[(2R,5S)-5-hydroxy-6...)
Affinity DataEC50:  130nMpH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Dartmouth College

LigandPNGBDBM20179((1S,2R,5S,10S,11S,14R,15R)-14-[(2R,4R)-4-hydroxy-6...)
Affinity DatapH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Dartmouth College

LigandPNGBDBM20178((1S,2R,5S,10S,11S,14R,15R)-14-[(2R,4S)-4-hydroxy-6...)
Affinity DataEC50:  5.90E+3nMpH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Dartmouth College

LigandPNGBDBM20177((1S,2R,5S,10S,11S,14R,15S)-14-[(2S,3R)-3-hydroxy-6...)
Affinity DataEC50:  325nMpH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Dartmouth College

LigandPNGBDBM20176((1S,2R,5S,10S,11S,14R,15S)-14-[(2S,3S)-3-hydroxy-6...)
Affinity DatapH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Dartmouth College

LigandPNGBDBM20175((1S,2R,5S,10S,11S,14S,15S)-14-[(2S)-2-hydroxy-6-me...)
Affinity DataEC50:  470nMpH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Dartmouth College

LigandPNGBDBM20164((1S,2R,5S,10S,11S,14R,15R)-14-[(2R)-4-[(2S)-3,3-di...)
Affinity DataEC50:  460nMpH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Dartmouth College

LigandPNGBDBM20174((1S,2R,5S,10S,11S,14R,15R)-14-[(2R)-4-[(2R)-3,3-di...)
Affinity DataEC50:  670nMpH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed