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Report error Found 35 with Last Name = 'stoppie' and Initial = 'p'
LigandPNGBDBM50110039(1-[2-(3-Cyclopropylmethoxy-4-methoxy-phenyl)-propy...)
Affinity DataKi:  3.5nMAssay Description:Displacement of [3H]rolipram from rat forebrain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)
Affinity DataKi:  11nMAssay Description:Inhibition of [3H]rolipram binding to Phosphodiesterase 4 of rat forebrain membraneMore data for this Ligand-Target Pair
LigandPNGBDBM14775(3-(cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-4-...)
Affinity DataKi:  26nMAssay Description:Inhibition of [3H]rolipram binding to Phosphodiesterase 4 of rat forebrain membraneMore data for this Ligand-Target Pair
LigandPNGBDBM50451480(CHEMBL2093042)
Affinity DataKi:  63nMAssay Description:Displacement of [3H]rolipram from rat forebrain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50110030(1-{2-[3-(Indan-2-yloxy)-4-methoxy-phenyl]-propyl}-...)
Affinity DataKi:  180nMAssay Description:Displacement of [3H]rolipram from rat forebrain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50366802(CHEMBL1788264)
Affinity DataKi:  220nMAssay Description:Displacement of [3H]rolipram from rat forebrain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM14775(3-(cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-4-...)
Affinity DataIC50:  0.200nMAssay Description:Inhibitory activity against recombinant phosphodiesterase 4B (PDE4B) of human mononuclear lymphocytesMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50219313(CHEMBL157812)
Affinity DataIC50: <10nMAssay Description:Inhibitory activity against recombinant phosphodiesterase 4B (PDE4B) of human mononuclear lymphocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50110030(1-{2-[3-(Indan-2-yloxy)-4-methoxy-phenyl]-propyl}-...)
Affinity DataIC50:  19nMAssay Description:Inhibitory activity against recombinant phosphodiesterase 4B (PDE4B) of human mononuclear lymphocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50451480(CHEMBL2093042)
Affinity DataIC50:  19nMAssay Description:Inhibitory activity against recombinant phosphodiesterase 4B (PDE4B) of human mononuclear lymphocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50110052(1-{2-[3-(Bicyclo[2.2.1]hept-2-yloxy)-4-methoxy-phe...)
Affinity DataIC50:  21nMAssay Description:Inhibitory activity against recombinant phosphodiesterase 4B (PDE4B) of human mononuclear lymphocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50110046(1-[2-(3-Cyclopropylmethoxy-4-difluoromethoxy-pheny...)
Affinity DataIC50:  22nMAssay Description:Inhibitory activity against recombinant phosphodiesterase 4B (PDE4B) of human mononuclear lymphocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50110038(1-{2-Fluoro-2-[3-(indan-2-yloxy)-4-methoxy-phenyl]...)
Affinity DataIC50:  24nMAssay Description:Inhibitory activity against recombinant phosphodiesterase 4B (PDE4B) of human mononuclear lymphocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50110040(1-[2-(3-Cyclopentyloxy-4-methoxy-phenyl)-propyl]-1...)
Affinity DataIC50:  24nMAssay Description:Inhibitory activity against recombinant phosphodiesterase 4B (PDE4B) of human mononuclear lymphocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50110034(1-{2-[4-Difluoromethoxy-3-(5-phenyl-pentyloxy)-phe...)
Affinity DataIC50:  28nMAssay Description:Inhibitory activity against recombinant phosphodiesterase 4B (PDE4B) of human mononuclear lymphocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50110037(1-[2-(3-Cyclopentyloxy-4-methoxy-phenyl)-propyl]-1...)
Affinity DataIC50:  30nMAssay Description:Inhibitory activity against recombinant phosphodiesterase 4B (PDE4B) of human mononuclear lymphocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50110051(1-{2-[4-Methoxy-3-(5-phenyl-pentyloxy)-phenyl]-pro...)
Affinity DataIC50:  36nMAssay Description:Inhibitory activity against recombinant phosphodiesterase 4B (PDE4B) of human mononuclear lymphocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50110047(1-[1-(3-Cyclopentyloxy-4-difluoromethoxy-phenyl)-c...)
Affinity DataIC50:  39nMAssay Description:Inhibitory activity against recombinant phosphodiesterase 4B (PDE4B) of human mononuclear lymphocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50110035(1-[2-(3-Cyclopropylmethoxy-4-methoxy-phenyl)-propy...)
Affinity DataIC50:  57nMAssay Description:Inhibitory activity against recombinant phosphodiesterase 4B (PDE4B) of human mononuclear lymphocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50366802(CHEMBL1788264)
Affinity DataIC50:  57nMAssay Description:Inhibitory activity against recombinant phosphodiesterase 4B (PDE4B) of human mononuclear lymphocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50110033(1-{2-[3-(2-Indan-2-yl-ethoxy)-4-methoxy-phenyl]-pr...)
Affinity DataIC50:  68nMAssay Description:Inhibitory activity against recombinant phosphodiesterase 4B (PDE4B) of human mononuclear lymphocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50346088((1r,4r)-4-cyano-4-(3-(cyclopentyloxy)-4-methoxyphe...)
Affinity DataIC50:  71nMAssay Description:Inhibitory activity against recombinant phosphodiesterase 4B (PDE4B) of human mononuclear lymphocytesMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50110039(1-[2-(3-Cyclopropylmethoxy-4-methoxy-phenyl)-propy...)
Affinity DataIC50:  86nMAssay Description:Inhibitory activity against recombinant phosphodiesterase 4B (PDE4B) of human mononuclear lymphocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50110036(1-[2-(3-Cyclopentyloxy-4-methoxy-phenyl)-ethyl]-1,...)
Affinity DataIC50:  110nMAssay Description:Inhibitory activity against recombinant phosphodiesterase 4B (PDE4B) of human mononuclear lymphocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50110045(1-{2-[4-Methoxy-3-(tetrahydro-furan-3-yloxy)-pheny...)
Affinity DataIC50:  196nMAssay Description:Inhibitory activity against recombinant phosphodiesterase 4B (PDE4B) of human mononuclear lymphocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50110029(1-{2-[4-Methoxy-3-(tetrahydro-furan-3-yloxy)-pheny...)
Affinity DataIC50:  241nMAssay Description:Inhibitory activity against recombinant phosphodiesterase 4B (PDE4B) of human mononuclear lymphocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50110032(1-[2-(3-Cyclopentyloxy-4-methoxy-phenyl)-1-methyl-...)
Affinity DataIC50:  277nMAssay Description:Inhibitory activity against recombinant phosphodiesterase 4B (PDE4B) of human mononuclear lymphocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50110048(1-{2-Fluoro-2-[4-methoxy-3-(tetrahydro-furan-3-ylo...)
Affinity DataIC50:  327nMAssay Description:Inhibitory activity against recombinant phosphodiesterase 4B (PDE4B) of human mononuclear lymphocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50110041(1-[1-(3-Cyclopentyloxy-4-methoxy-phenyl)-cycloprop...)
Affinity DataIC50:  341nMAssay Description:Inhibitory activity against recombinant phosphodiesterase 4B (PDE4B) of human mononuclear lymphocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50110043(1-[2-(3-Cyclopentyloxy-4-methoxy-phenyl)-2-methyl-...)
Affinity DataIC50:  367nMAssay Description:Inhibitory activity against recombinant phosphodiesterase 4B (PDE4B) of human mononuclear lymphocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50110031(1-{2-Hydroxy-2-[3-(indan-2-yloxy)-4-methoxy-phenyl...)
Affinity DataIC50:  399nMAssay Description:Inhibitory activity against recombinant phosphodiesterase 4B (PDE4B) of human mononuclear lymphocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50110044(1-[2-(3-Cyclopentyloxy-4-methoxy-phenyl)-2-oxo-eth...)
Affinity DataIC50:  486nMAssay Description:Inhibitory activity against recombinant phosphodiesterase 4B (PDE4B) of human mononuclear lymphocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)
Affinity DataIC50:  741nMAssay Description:Inhibitory activity against recombinant phosphodiesterase 4B (PDE4B) of human mononuclear lymphocytesMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50110050(1-{2-Hydroxy-2-[4-methoxy-3-(tetrahydro-furan-3-yl...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity against recombinant phosphodiesterase 4B (PDE4B) of human mononuclear lymphocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50110049(1-[2-(3-Cyclopentyloxy-4-trifluoromethoxy-phenyl)-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity against recombinant phosphodiesterase 4B (PDE4B) of human mononuclear lymphocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed