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TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM81462((R)-Trihexyphenidyl | (S)-Trihexyphenidyl | Benzhe...)
Affinity DataKi:  0.370nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM50176065(4-DAMP | 4-Diphenylacetoxy-1,1-dimethyl-piperidini...)
Affinity DataKi:  0.520nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM50176065(4-DAMP | 4-Diphenylacetoxy-1,1-dimethyl-piperidini...)
Affinity DataKi:  0.580nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM81462((R)-Trihexyphenidyl | (S)-Trihexyphenidyl | Benzhe...)
Affinity DataKi:  0.830nMMore data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM50176065(4-DAMP | 4-Diphenylacetoxy-1,1-dimethyl-piperidini...)
Affinity DataKi:  1.05nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM50176065(4-DAMP | 4-Diphenylacetoxy-1,1-dimethyl-piperidini...)
Affinity DataKi:  1.17nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM81898((R)-Hexbutinol | (S)-Hexbutinol | CAS_2054312 | CA...)
Affinity DataKi:  2.18nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM81462((R)-Trihexyphenidyl | (S)-Trihexyphenidyl | Benzhe...)
Affinity DataKi:  2.45nMMore data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM81898((R)-Hexbutinol | (S)-Hexbutinol | CAS_2054312 | CA...)
Affinity DataKi:  3.02nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM50176065(4-DAMP | 4-Diphenylacetoxy-1,1-dimethyl-piperidini...)
Affinity DataKi:  3.80nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM81900(AQ-RA 741 | CAS_129989 | NSC_129989)
Affinity DataKi:  4.27nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM81462((R)-Trihexyphenidyl | (S)-Trihexyphenidyl | Benzhe...)
Affinity DataKi:  5.01nMMore data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM81898((R)-Hexbutinol | (S)-Hexbutinol | CAS_2054312 | CA...)
Affinity DataKi:  5.5nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM81901(AF-DX 384 | CAS_119356 | CHEMBL279453 | NSC_119356)
Affinity DataKi:  6.03nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM39341(11-[(4-methylpiperazin-1-yl)acetyl]-5,11-dihydro-6...)
Affinity DataKi:  6.31nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM81900(AQ-RA 741 | CAS_129989 | NSC_129989)
Affinity DataKi:  6.46nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM81462((R)-Trihexyphenidyl | (S)-Trihexyphenidyl | Benzhe...)
Affinity DataKi:  7.08nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM50071173((3R,4R,4aS,8aR)-4-[(E)-2-((2S,6S)-1,6-Dimethyl-pip...)
Affinity DataKi:  10nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM81901(AF-DX 384 | CAS_119356 | CHEMBL279453 | NSC_119356)
Affinity DataKi:  10nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM50071173((3R,4R,4aS,8aR)-4-[(E)-2-((2S,6S)-1,6-Dimethyl-pip...)
Affinity DataKi:  11.0nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM50064176(CHEMBL27673 | CHEMBL500996 | METHOCTRAMINE | N,N''...)
Affinity DataKi:  13.2nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM81897(CAS_5311091 | NSC_5311091 | p-F-HHSiD)
Affinity DataKi:  15.5nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM81898((R)-Hexbutinol | (S)-Hexbutinol | CAS_2054312 | CA...)
Affinity DataKi:  19.5nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM81898((R)-Hexbutinol | (S)-Hexbutinol | CAS_2054312 | CA...)
Affinity DataKi:  20.9nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM81897(CAS_5311091 | NSC_5311091 | p-F-HHSiD)
Affinity DataKi:  22.4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM81898((R)-Hexbutinol | (S)-Hexbutinol | CAS_2054312 | CA...)
Affinity DataKi:  26.3nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM81900(AQ-RA 741 | CAS_129989 | NSC_129989)
Affinity DataKi:  28.8nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM81901(AF-DX 384 | CAS_119356 | CHEMBL279453 | NSC_119356)
Affinity DataKi:  30.9nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM50064176(CHEMBL27673 | CHEMBL500996 | METHOCTRAMINE | N,N''...)
Affinity DataKi:  31.6nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM81897(CAS_5311091 | NSC_5311091 | p-F-HHSiD)
Affinity DataKi:  31.6nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM39341(11-[(4-methylpiperazin-1-yl)acetyl]-5,11-dihydro-6...)
Affinity DataKi:  37.1nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM81898((R)-Hexbutinol | (S)-Hexbutinol | CAS_2054312 | CA...)
Affinity DataKi:  45.7nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM50064176(CHEMBL27673 | CHEMBL500996 | METHOCTRAMINE | N,N''...)
Affinity DataKi:  50.1nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM81896(6H-Pyrido[2,3-b][1,4]benzodiazepin-6-one,11-[2-[2-...)
Affinity DataKi:  55.0nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM81900(AQ-RA 741 | CAS_129989 | NSC_129989)
Affinity DataKi:  63.1nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM81901(AF-DX 384 | CAS_119356 | CHEMBL279453 | NSC_119356)
Affinity DataKi:  66.1nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM81898((R)-Hexbutinol | (S)-Hexbutinol | CAS_2054312 | CA...)
Affinity DataKi:  72.4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM81898((R)-Hexbutinol | (S)-Hexbutinol | CAS_2054312 | CA...)
Affinity DataKi:  75.9nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM39341(11-[(4-methylpiperazin-1-yl)acetyl]-5,11-dihydro-6...)
Affinity DataKi:  89.1nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM50071173((3R,4R,4aS,8aR)-4-[(E)-2-((2S,6S)-1,6-Dimethyl-pip...)
Affinity DataKi:  93.3nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM81897(CAS_5311091 | NSC_5311091 | p-F-HHSiD)
Affinity DataKi:  93.3nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM50071173((3R,4R,4aS,8aR)-4-[(E)-2-((2S,6S)-1,6-Dimethyl-pip...)
Affinity DataKi:  107nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM81462((R)-Trihexyphenidyl | (S)-Trihexyphenidyl | Benzhe...)
Affinity DataKi:  123nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM81897(CAS_5311091 | NSC_5311091 | p-F-HHSiD)
Affinity DataKi:  132nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM50064176(CHEMBL27673 | CHEMBL500996 | METHOCTRAMINE | N,N''...)
Affinity DataKi:  135nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM39341(11-[(4-methylpiperazin-1-yl)acetyl]-5,11-dihydro-6...)
Affinity DataKi:  138nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM81896(6H-Pyrido[2,3-b][1,4]benzodiazepin-6-one,11-[2-[2-...)
Affinity DataKi:  162nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM50064176(CHEMBL27673 | CHEMBL500996 | METHOCTRAMINE | N,N''...)
Affinity DataKi:  214nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM39341(11-[(4-methylpiperazin-1-yl)acetyl]-5,11-dihydro-6...)
Affinity DataKi:  224nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM81462((R)-Trihexyphenidyl | (S)-Trihexyphenidyl | Benzhe...)
Affinity DataKi:  269nMMore data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

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