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TargetAryl hydrocarbon receptor(Human)
Wisconsin Alumni Research Foundation

US Patent
LigandPNGBDBM50049065(CHEMBL3319497 | US9969686, Compound 6 | US10730833...)
Affinity DataEC50:  270nMAssay Description:AhR readily binds to various endogenous and xenobiotic polyaromatic heterocycles.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAryl hydrocarbon receptor(Human)
Wisconsin Alumni Research Foundation

US Patent
LigandPNGBDBM50049064(CHEMBL3319498 | US9969686, Compound 11a | US107308...)
Affinity DataEC50:  93nMAssay Description:AhR readily binds to various endogenous and xenobiotic polyaromatic heterocycles.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAryl hydrocarbon receptor(Human)
Wisconsin Alumni Research Foundation

US Patent
LigandPNGBDBM50049063(CHEMBL3319499 | US9969686, Compound 11b | US107308...)
Affinity DataEC50:  320nMAssay Description:AhR readily binds to various endogenous and xenobiotic polyaromatic heterocycles.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAryl hydrocarbon receptor(Human)
Wisconsin Alumni Research Foundation

US Patent
LigandPNGBDBM50049062(CHEMBL3319500 | US9969686, Compound 11c | US107308...)
Affinity DataEC50:  230nMAssay Description:AhR readily binds to various endogenous and xenobiotic polyaromatic heterocycles.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAryl hydrocarbon receptor(Human)
Wisconsin Alumni Research Foundation

US Patent
LigandPNGBDBM50049061(CHEMBL3319501 | US9969686, Compound 11d | US107308...)
Affinity DataEC50:  55nMAssay Description:AhR readily binds to various endogenous and xenobiotic polyaromatic heterocycles.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAryl hydrocarbon receptor(Human)
Wisconsin Alumni Research Foundation

US Patent
LigandPNGBDBM50049060(CHEMBL3319502 | US9969686, Compound 6' | US1073083...)
Affinity DataEC50:  215nMAssay Description:AhR readily binds to various endogenous and xenobiotic polyaromatic heterocycles.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAryl hydrocarbon receptor(Human)
Wisconsin Alumni Research Foundation

US Patent
LigandPNGBDBM50049059(CHEMBL3319503 | US9969686, Compound 10a | US107308...)
Affinity DataEC50: >6.70E+3nMAssay Description:AhR readily binds to various endogenous and xenobiotic polyaromatic heterocycles.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAryl hydrocarbon receptor(Human)
Wisconsin Alumni Research Foundation

US Patent
LigandPNGBDBM50049058(CHEMBL3319504 | US9969686, Compound 10c | US107308...)
Affinity DataEC50:  94nMAssay Description:AhR readily binds to various endogenous and xenobiotic polyaromatic heterocycles.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAryl hydrocarbon receptor(Human)
Wisconsin Alumni Research Foundation

US Patent
LigandPNGBDBM50049057(CHEMBL3319505 | US9969686, Compound 10d | US107308...)
Affinity DataEC50:  86nMAssay Description:AhR readily binds to various endogenous and xenobiotic polyaromatic heterocycles.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAryl hydrocarbon receptor(Human)
Wisconsin Alumni Research Foundation

US Patent
LigandPNGBDBM50049065(CHEMBL3319497 | US9969686, Compound 6 | US10730833...)
Affinity DataEC50:  270nMAssay Description:This assay measures the induction of cytochrome P450-1A1 (CYP1A1), which is a major outcome of AhR activation. Whyte, J. J.; Jung, R. E.; Schmitt, C....More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAryl hydrocarbon receptor(Human)
Wisconsin Alumni Research Foundation

US Patent
LigandPNGBDBM50049064(CHEMBL3319498 | US9969686, Compound 11a | US107308...)
Affinity DataEC50:  93nMAssay Description:This assay measures the induction of cytochrome P450-1A1 (CYP1A1), which is a major outcome of AhR activation. Whyte, J. J.; Jung, R. E.; Schmitt, C....More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAryl hydrocarbon receptor(Human)
Wisconsin Alumni Research Foundation

US Patent
LigandPNGBDBM50049063(CHEMBL3319499 | US9969686, Compound 11b | US107308...)
Affinity DataEC50:  320nMAssay Description:This assay measures the induction of cytochrome P450-1A1 (CYP1A1), which is a major outcome of AhR activation. Whyte, J. J.; Jung, R. E.; Schmitt, C....More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAryl hydrocarbon receptor(Human)
Wisconsin Alumni Research Foundation

US Patent
LigandPNGBDBM50049062(CHEMBL3319500 | US9969686, Compound 11c | US107308...)
Affinity DataEC50:  230nMAssay Description:This assay measures the induction of cytochrome P450-1A1 (CYP1A1), which is a major outcome of AhR activation. Whyte, J. J.; Jung, R. E.; Schmitt, C....More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAryl hydrocarbon receptor(Human)
Wisconsin Alumni Research Foundation

US Patent
LigandPNGBDBM50049061(CHEMBL3319501 | US9969686, Compound 11d | US107308...)
Affinity DataEC50:  55nMAssay Description:This assay measures the induction of cytochrome P450-1A1 (CYP1A1), which is a major outcome of AhR activation. Whyte, J. J.; Jung, R. E.; Schmitt, C....More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAryl hydrocarbon receptor(Human)
Wisconsin Alumni Research Foundation

US Patent
LigandPNGBDBM50049060(CHEMBL3319502 | US9969686, Compound 6' | US1073083...)
Affinity DataEC50:  215nMAssay Description:This assay measures the induction of cytochrome P450-1A1 (CYP1A1), which is a major outcome of AhR activation. Whyte, J. J.; Jung, R. E.; Schmitt, C....More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAryl hydrocarbon receptor(Human)
Wisconsin Alumni Research Foundation

US Patent
LigandPNGBDBM50049059(CHEMBL3319503 | US9969686, Compound 10a | US107308...)
Affinity DataEC50: >6.70E+3nMAssay Description:This assay measures the induction of cytochrome P450-1A1 (CYP1A1), which is a major outcome of AhR activation. Whyte, J. J.; Jung, R. E.; Schmitt, C....More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAryl hydrocarbon receptor(Human)
Wisconsin Alumni Research Foundation

US Patent
LigandPNGBDBM50049058(CHEMBL3319504 | US9969686, Compound 10c | US107308...)
Affinity DataEC50:  94nMAssay Description:This assay measures the induction of cytochrome P450-1A1 (CYP1A1), which is a major outcome of AhR activation. Whyte, J. J.; Jung, R. E.; Schmitt, C....More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAryl hydrocarbon receptor(Human)
Wisconsin Alumni Research Foundation

US Patent
LigandPNGBDBM50049057(CHEMBL3319505 | US9969686, Compound 10d | US107308...)
Affinity DataEC50:  86nMAssay Description:This assay measures the induction of cytochrome P450-1A1 (CYP1A1), which is a major outcome of AhR activation. Whyte, J. J.; Jung, R. E.; Schmitt, C....More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052113((2-Methoxy-ethyl)-carbamic acid (3R,4aR,5S,6S,6aS,...)
Affinity DataEC50:  1.60E+3nMAssay Description:Conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052136(3-((3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-Acetoxy-10,1...)
Affinity DataEC50:  3.50E+3nMAssay Description:Conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052111((2-Methoxy-ethyl)-carbamic acid (3R,4aR,5S,6S,6aS,...)
Affinity DataEC50:  3.10E+3nMAssay Description:Conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052125(3-((3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5,10,10b-Trihy...)
Affinity DataEC50: >2.00E+3nMAssay Description:Ability to activate the conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052127(Acetic acid (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-10,10...)
Affinity DataEC50: >2.00E+3nMAssay Description:Ability to activate the conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052144((2-Hydroxy-ethyl)-carbamic acid (3R,4aR,5S,6S,6aS,...)
Affinity DataEC50: >2.00E+3nMAssay Description:Ability to activate the conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052119((3,3-Dimethyl-butyl)-carbamic acid (3R,4aR,5S,6S,6...)
Affinity DataEC50:  2.10E+3nMAssay Description:Conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052134(Acetic acid (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-6-(3,...)
Affinity DataEC50: >2.00E+3nMAssay Description:Ability to activate the conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052132(Acetic acid (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-6-(2-...)
Affinity DataEC50:  2.00E+3nMAssay Description:Conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052112((3,3-Dimethyl-butyl)-carbamic acid (3R,4aR,5S,6S,6...)
Affinity DataEC50:  9.60E+3nMAssay Description:Conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052113((2-Methoxy-ethyl)-carbamic acid (3R,4aR,5S,6S,6aS,...)
Affinity DataEC50: >2.00E+3nMAssay Description:Ability to activate the conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052116(Isobutyl-carbamic acid (3R,4aR,5S,6S,6aS,10S,10aR,...)
Affinity DataEC50:  2.70E+3nMAssay Description:Conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052131(Propyl-carbamic acid (3R,4aR,5S,6S,6aS,10S,10aR,10...)
Affinity DataEC50:  1.30E+3nMAssay Description:Conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052133(Acetic acid (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-6-cyc...)
Affinity DataEC50:  6.60E+3nMAssay Description:Conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052140(Acetic acid (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-10,10...)
Affinity DataEC50:  500nMAssay Description:Conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052120(Isobutyl-carbamic acid (3R,4aR,5S,6S,6aS,10S,10aR,...)
Affinity DataEC50: >2.00E+3nMAssay Description:Ability to activate the conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052126((2-Piperidin-1-yl-ethyl)-carbamic acid (3R,4aR,5S,...)
Affinity DataEC50:  1.20E+3nMAssay Description:Conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052115((2-Dimethylamino-ethyl)-carbamic acid (3R,4aR,5S,6...)
Affinity DataEC50: >2.00E+3nMAssay Description:Ability to activate the conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052148((2-Piperidin-1-yl-ethyl)-carbamic acid (3R,4aR,5S,...)
Affinity DataEC50:  1.70E+3nMAssay Description:Conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052139(Allyl-carbamic acid (3R,4aR,5S,6S,6aS,10S,10aR,10b...)
Affinity DataEC50: >2.00E+3nMAssay Description:Ability to activate the conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052146((2-Pyridin-2-yl-ethyl)-carbamic acid (3R,4aR,5S,6S...)
Affinity DataEC50:  1.80E+3nMAssay Description:Conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052122(Acetic acid (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-10,10...)
Affinity DataEC50: >2.00E+3nMAssay Description:Ability to activate the conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052121(3-((3R,4aR,5S,6S,6aS,10S,10aR,10bS)-6,10,10b-Trihy...)
Affinity DataEC50: >2.00E+3nMAssay Description:Ability to activate the conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052134(Acetic acid (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-6-(3,...)
Affinity DataEC50:  8.10E+3nMAssay Description:Conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052145([2-(4-Amino-phenyl)-ethyl]-carbamic acid (3R,4aR,5...)
Affinity DataEC50: >2.00E+3nMAssay Description:Ability to activate the conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052133(Acetic acid (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-6-cyc...)
Affinity DataEC50: >2.00E+3nMAssay Description:Ability to activate the conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052149(Acetic acid (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-6-all...)
Affinity DataEC50: >2.00E+3nMAssay Description:Ability to activate the conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052138(Allyl-carbamic acid (3R,4aR,5S,6S,6aS,10S,10aR,10b...)
Affinity DataEC50: >2.00E+3nMAssay Description:Ability to activate the conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052114(Phenethyl-carbamic acid (3R,4aR,5S,6S,6aS,10S,10aR...)
Affinity DataEC50: >2.00E+3nMAssay Description:Ability to activate the conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052130((2-Pyridin-2-yl-ethyl)-carbamic acid (3R,4aR,5S,6S...)
Affinity DataEC50:  1.10E+3nMAssay Description:Conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052135((2-Dimethylamino-ethyl)-carbamic acid (3R,4aR,5S,6...)
Affinity DataEC50: >2.00E+3nMAssay Description:Ability to activate the conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052128(Cyclohexylmethyl-carbamic acid (3R,4aR,5S,6S,6aS,1...)
Affinity DataEC50: >2.00E+3nMAssay Description:Ability to activate the conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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