Compile Data Set for Download or QSAR
Report error Found 524 with Last Name = 'temml' and Initial = 'v'
TargetEstrogen receptor(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM50130177(2,6,8-Trihydroxy-10,11-dioxa-benzo[b]fluoren-5-one...)
Affinity DataEC50:  21nMAssay Description:Agonist activity at human ERalpha expressed in yeast cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAryl hydrocarbon receptor(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM50130177(2,6,8-Trihydroxy-10,11-dioxa-benzo[b]fluoren-5-one...)
Affinity DataEC50:  1.34E+3nMAssay Description:Agonist activity at human AHR expressed in yeast cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Sassari

Curated by ChEMBL
LigandPNGBDBM50515335(CHEMBL4532589)
Affinity DataEC50:  600nMAssay Description:Agonist activity at human alpha4beta2 nAChR expressed in GH4C1 cells assessed as increase in inward channel current measured after 3 to 4 days at -70...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Sassari

Curated by ChEMBL
LigandPNGBDBM50515320(CHEMBL4441630)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at human alpha4beta2 nAChR expressed in GH4C1 cells assessed as increase in inward channel current measured after 3 to 4 days at -70...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
University of Sassari

Curated by ChEMBL
LigandPNGBDBM50515333(CHEMBL4460815)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human alpha3beta4 nAChR expressed in GH4C1 cells assessed as increase in inward channel current measured after 3 to 4 days at -70...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Sassari

Curated by ChEMBL
LigandPNGBDBM50515333(CHEMBL4460815)
Affinity DataEC50:  520nMAssay Description:Agonist activity at human alpha4beta2 nAChR expressed in GH4C1 cells assessed as increase in inward channel current measured after 3 to 4 days at -70...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
University of Sassari

Curated by ChEMBL
LigandPNGBDBM50515335(CHEMBL4532589)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human alpha3beta4 nAChR expressed in GH4C1 cells assessed as increase in inward channel current measured after 3 to 4 days at -70...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50521309(CHEMBL4467796)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant human sEH preincubated for 10 mins followed by PHOME substrate addition and measured after 60 mins by fluorescence-based as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50521307(CHEMBL4559364)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of recombinant human sEH preincubated for 10 mins followed by PHOME substrate addition and measured after 60 mins by fluorescence-based as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50521297(CHEMBL4584048)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human sEH preincubated for 10 mins followed by PHOME substrate addition and measured after 60 mins by fluorescence-based as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50521298(CHEMBL4474511)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of recombinant human sEH preincubated for 10 mins followed by PHOME substrate addition and measured after 60 mins by fluorescence-based as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50521295(CHEMBL4513805)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of recombinant human sEH preincubated for 10 mins followed by PHOME substrate addition and measured after 60 mins by fluorescence-based as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM13065(5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluor...)
Affinity DataIC50: 6nMAssay Description:Inhibition of ovine COX-1 assessed as reduction in PGE2 production using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mins foll...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50521291(CHEMBL4467433)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of recombinant human sEH preincubated for 10 mins followed by PHOME substrate addition and measured after 60 mins by fluorescence-based as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Sannio

Curated by ChEMBL
LigandPNGBDBM50624927(CHEMBL5398068)
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant human 5-lipoxygenase expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 5 to 10 mins w...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Sannio

Curated by ChEMBL
LigandPNGBDBM50624931(CHEMBL5421129)
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant human 5-lipoxygenase expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 5 to 10 mins w...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Sannio

Curated by ChEMBL
LigandPNGBDBM50624929(CHEMBL5395696)
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human 5-lipoxygenase expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 5 to 10 mins w...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50521303(CHEMBL4578414)
Affinity DataIC50: 9.10nMAssay Description:Inhibition of recombinant human sEH preincubated for 10 mins followed by PHOME substrate addition and measured after 60 mins by fluorescence-based as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50521306(CHEMBL4585429)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human sEH preincubated for 10 mins followed by PHOME substrate addition and measured after 60 mins by fluorescence-based as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Sannio

Curated by ChEMBL
LigandPNGBDBM50624928(CHEMBL5413117)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human 5-lipoxygenase expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 5 to 10 mins w...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Sannio

Curated by ChEMBL
LigandPNGBDBM50624930(CHEMBL5401317)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human 5-lipoxygenase expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 5 to 10 mins w...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50521302(CHEMBL4439758)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human sEH preincubated for 10 mins followed by PHOME substrate addition and measured after 60 mins by fluorescence-based as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50521292(CHEMBL4447668)
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant human sEH preincubated for 10 mins followed by PHOME substrate addition and measured after 60 mins by fluorescence-based as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50521300(CHEMBL4456287)
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human sEH preincubated for 10 mins followed by PHOME substrate addition and measured after 60 mins by fluorescence-based as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50521304(CHEMBL4464098)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human sEH preincubated for 10 mins followed by PHOME substrate addition and measured after 60 mins by fluorescence-based as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50521296(CHEMBL4464435)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human sEH preincubated for 10 mins followed by PHOME substrate addition and measured after 60 mins by fluorescence-based as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Sannio

Curated by ChEMBL
LigandPNGBDBM50624922(CHEMBL5418840)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human 5-lipoxygenase expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 5 to 10 mins w...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Sannio

Curated by ChEMBL
LigandPNGBDBM50624923(CHEMBL5413658)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human 5-lipoxygenase expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 5 to 10 mins w...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50557581(CHEMBL4755060)
Affinity DataIC50: 21nMAssay Description:Competitive inhibition of ovine COX-1 assessed as reduction in PGE2 production using 250 nM arachidonic acid as substrate preincubated with enzyme fo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50521293(CHEMBL4291038)
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant human sEH preincubated for 10 mins followed by PHOME substrate addition and measured after 60 mins by fluorescence-based as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50521301(CHEMBL4572575)
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human sEH preincubated for 10 mins followed by PHOME substrate addition and measured after 60 mins by fluorescence-based as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50521299(CHEMBL4470478)
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant human sEH preincubated for 10 mins followed by PHOME substrate addition and measured after 60 mins by fluorescence-based as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Sannio

Curated by ChEMBL
LigandPNGBDBM50231998(CHEMBL4085835)
Affinity DataIC50: 28nMAssay Description:Inhibition of 5-lipoxygenase in human neutrophils assessed as inhibition of A23187-induced product formation using arachidonic acid as substrate prei...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Sannio

Curated by ChEMBL
LigandPNGBDBM50624926(CHEMBL5425532)
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human 5-lipoxygenase expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 5 to 10 mins w...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Sannio

Curated by ChEMBL
LigandPNGBDBM50231999(CHEMBL4103758)
Affinity DataIC50: 30nMAssay Description:Inhibition of 5-LOX in human PMNL cellsMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Sannio

Curated by ChEMBL
LigandPNGBDBM50231991(CHEMBL4093584)
Affinity DataIC50: 30nMAssay Description:Inhibition of 5-lipoxygenase in human neutrophils assessed as inhibition of A23187-induced product formation using arachidonic acid as substrate prei...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50521305(CHEMBL4468253)
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant human sEH preincubated for 10 mins followed by PHOME substrate addition and measured after 60 mins by fluorescence-based as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Sannio

Curated by ChEMBL
LigandPNGBDBM50576500(CHEMBL4847874)
Affinity DataIC50: 40nMAssay Description:Inhibition of 5-LOX in human PMNL assessed as reduction in 5-LOX product formation preincubated for 10 mins before addition of AA and A23187 and meas...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Sannio

Curated by ChEMBL
LigandPNGBDBM50624925(CHEMBL5441068)
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant human 5-lipoxygenase expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 5 to 10 mins w...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM50130177(2,6,8-Trihydroxy-10,11-dioxa-benzo[b]fluoren-5-one...)
Affinity DataIC50: 49nMAssay Description:Inhibition of human 17beta-HSD1 expressed in HEK293 cell lysates incubated for 10 mins using [2,4,6,7-3H]-estrone and NADPH by scintillation counting...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Sannio

Curated by ChEMBL
LigandPNGBDBM50380205(NYMPHAEOL A)
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant 5-LOX assessed as reduction in leukotriene B4 production pre-incubated for 10 mins before arachidonic acid addition a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Sannio

Curated by ChEMBL
LigandPNGBDBM50555731(CHEMBL4743283)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant human 5-LO expressed in Escherichia coli BL21(DE3) assessed as reduction in LTB4 and 5-H(P)ETE formation using arachidonic ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Sannio

Curated by ChEMBL
LigandPNGBDBM50576502(CHEMBL3092679)
Affinity DataIC50: 50nMAssay Description:Inhibition of 5-LOX in human PMNL assessed as reduction in 5-LOX product formation preincubated for 10 mins before addition of AA and A23187 and meas...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Sannio

Curated by ChEMBL
LigandPNGBDBM50576500(CHEMBL4847874)
Affinity DataIC50: 50nMAssay Description:Inhibition of 5-LOX in human PMNL assessed as reduction in 5-LOX product formation preincubated for 10 mins before addition of A23187 and measured af...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Sannio

Curated by ChEMBL
LigandPNGBDBM50624921(4-Phenylcatechol | CHEMBL475398)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant human 5-lipoxygenase expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 5 to 10 mins w...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Sannio

Curated by ChEMBL
LigandPNGBDBM50527521(CHEMBL4463788)
Affinity DataIC50: 57nMAssay Description:Inhibition of recombinant human 5-LO expressed in Escherichia coli BL21(DE3) assessed as reduction in LTB4 and 5-H(P)ETE formation using arachidonic ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Sannio

Curated by ChEMBL
LigandPNGBDBM50468223(CHEMBL463675)
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant 5-LOX assessed as reduction in leukotriene B4 production pre-incubated for 10 mins before arachidonic acid addition a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Sannio

Curated by ChEMBL
LigandPNGBDBM50527521(CHEMBL4463788)
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli BL21 (DE3) cells preincubated for 10 mins followed by arachidonic acid addition a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Sannio

Curated by ChEMBL
LigandPNGBDBM50231998(CHEMBL4085835)
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant human 5-lipoxygenase expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins follow...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50521310(CHEMBL4529502)
Affinity DataIC50: 62nMAssay Description:Inhibition of recombinant human sEH preincubated for 10 mins followed by PHOME substrate addition and measured after 60 mins by fluorescence-based as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Displayed 1 to 50 (of 524 total ) | Next | Last >>
Jump to: