Compile Data Set for Download or QSAR
Report error Found 3955 with Last Name = 'thomas' and Initial = 'm'
LigandPNGBDBM576220(WO2022109573, Compound 4)
Affinity DataEC50: <500nMAssay Description:ssing chamber experiments were performed using human bronchial epithelial (HBE) cells derived from CF subjects heterozygous for F508del and a minimal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
WIPO WO2022109573

LigandPNGBDBM576221(WO2022109573, Compound 7)
Affinity DataEC50: <500nMAssay Description:ssing chamber experiments were performed using human bronchial epithelial (HBE) cells derived from CF subjects heterozygous for F508del and a minimal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
WIPO WO2022109573

LigandPNGBDBM576222(WO2022109573, Compound 8)
Affinity DataEC50: <500nMAssay Description:ssing chamber experiments were performed using human bronchial epithelial (HBE) cells derived from CF subjects heterozygous for F508del and a minimal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
WIPO WO2022109573

LigandPNGBDBM576223(WO2022109573, Compound 9)
Affinity DataEC50: <500nMAssay Description:ssing chamber experiments were performed using human bronchial epithelial (HBE) cells derived from CF subjects heterozygous for F508del and a minimal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
WIPO WO2022109573

LigandPNGBDBM576224(WO2022109573, Compound 13)
Affinity DataEC50: <500nMAssay Description:ssing chamber experiments were performed using human bronchial epithelial (HBE) cells derived from CF subjects heterozygous for F508del and a minimal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
WIPO WO2022109573

LigandPNGBDBM576225(WO2022109573, Compound 14)
Affinity DataEC50: <500nMAssay Description:ssing chamber experiments were performed using human bronchial epithelial (HBE) cells derived from CF subjects heterozygous for F508del and a minimal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
WIPO WO2022109573

LigandPNGBDBM576226(WO2022109573, Compound 17)
Affinity DataEC50: <500nMAssay Description:ssing chamber experiments were performed using human bronchial epithelial (HBE) cells derived from CF subjects heterozygous for F508del and a minimal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
WIPO WO2022109573

LigandPNGBDBM576227(WO2022109573, Compound 18)
Affinity DataEC50: <500nMAssay Description:ssing chamber experiments were performed using human bronchial epithelial (HBE) cells derived from CF subjects heterozygous for F508del and a minimal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
WIPO WO2022109573

LigandPNGBDBM576228(WO2022109573, Compound 19)
Affinity DataEC50: <500nMAssay Description:ssing chamber experiments were performed using human bronchial epithelial (HBE) cells derived from CF subjects heterozygous for F508del and a minimal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
WIPO WO2022109573

LigandPNGBDBM576229(WO2022109573, Compound 21)
Affinity DataEC50: <500nMAssay Description:ssing chamber experiments were performed using human bronchial epithelial (HBE) cells derived from CF subjects heterozygous for F508del and a minimal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
WIPO WO2022109573

LigandPNGBDBM576230(WO2022109573, Compound 23)
Affinity DataEC50: <500nMAssay Description:ssing chamber experiments were performed using human bronchial epithelial (HBE) cells derived from CF subjects heterozygous for F508del and a minimal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
WIPO WO2022109573

LigandPNGBDBM576231(WO2022109573, Compound 24)
Affinity DataEC50: <500nMAssay Description:ssing chamber experiments were performed using human bronchial epithelial (HBE) cells derived from CF subjects heterozygous for F508del and a minimal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
WIPO WO2022109573

LigandPNGBDBM576232(WO2022109573, Compound 25)
Affinity DataEC50: <500nMAssay Description:ssing chamber experiments were performed using human bronchial epithelial (HBE) cells derived from CF subjects heterozygous for F508del and a minimal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
WIPO WO2022109573

LigandPNGBDBM576233(WO2022109573, Compound 29)
Affinity DataEC50: <500nMAssay Description:ssing chamber experiments were performed using human bronchial epithelial (HBE) cells derived from CF subjects heterozygous for F508del and a minimal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
WIPO WO2022109573

LigandPNGBDBM576234(WO2022109573, Compound 31)
Affinity DataEC50: <500nMAssay Description:ssing chamber experiments were performed using human bronchial epithelial (HBE) cells derived from CF subjects heterozygous for F508del and a minimal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
WIPO WO2022109573

LigandPNGBDBM576235(WO2022109573, Compound 32)
Affinity DataEC50: <500nMAssay Description:ssing chamber experiments were performed using human bronchial epithelial (HBE) cells derived from CF subjects heterozygous for F508del and a minimal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
WIPO WO2022109573

LigandPNGBDBM576236(WO2022109573, Compound 34)
Affinity DataEC50: <500nMAssay Description:ssing chamber experiments were performed using human bronchial epithelial (HBE) cells derived from CF subjects heterozygous for F508del and a minimal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
WIPO WO2022109573

LigandPNGBDBM576237(WO2022109573, Compound 36)
Affinity DataEC50: <500nMAssay Description:ssing chamber experiments were performed using human bronchial epithelial (HBE) cells derived from CF subjects heterozygous for F508del and a minimal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
WIPO WO2022109573

LigandPNGBDBM576238(WO2022109573, Compound 37)
Affinity DataEC50: <500nMAssay Description:ssing chamber experiments were performed using human bronchial epithelial (HBE) cells derived from CF subjects heterozygous for F508del and a minimal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
WIPO WO2022109573

LigandPNGBDBM576239(WO2022109573, Compound 41)
Affinity DataEC50: <500nMAssay Description:ssing chamber experiments were performed using human bronchial epithelial (HBE) cells derived from CF subjects heterozygous for F508del and a minimal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
WIPO WO2022109573

LigandPNGBDBM576240(WO2022109573, Compound 45)
Affinity DataEC50: <500nMAssay Description:ssing chamber experiments were performed using human bronchial epithelial (HBE) cells derived from CF subjects heterozygous for F508del and a minimal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
WIPO WO2022109573

LigandPNGBDBM576241(WO2022109573, Compound 46)
Affinity DataEC50: <500nMAssay Description:ssing chamber experiments were performed using human bronchial epithelial (HBE) cells derived from CF subjects heterozygous for F508del and a minimal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
WIPO WO2022109573

TargetProbable G-protein coupled receptor 142(Human)
Lilly China Research and Development Center (Lcrdc)

Curated by ChEMBL
LigandPNGBDBM50544789(CHEMBL4647315)
Affinity DataEC50:  30nMAssay Description:Agonist activity at human GPR142 receptor expressed in HEK293 cells assessed as accumulation of inositol phosphate incubated for 1 hr followed by IP1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProbable G-protein coupled receptor 142(Human)
Lilly China Research and Development Center (Lcrdc)

Curated by ChEMBL
LigandPNGBDBM50544790(CHEMBL4648456)
Affinity DataEC50:  131nMAssay Description:Agonist activity at human GPR142 receptor expressed in HEK293 cells assessed as accumulation of inositol phosphate incubated for 1 hr followed by IP1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProbable G-protein coupled receptor 142(Human)
Lilly China Research and Development Center (Lcrdc)

Curated by ChEMBL
LigandPNGBDBM50544791(CHEMBL4642188)
Affinity DataEC50:  52nMAssay Description:Agonist activity at human GPR142 receptor expressed in HEK293 cells assessed as accumulation of inositol phosphate incubated for 1 hr followed by IP1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProbable G-protein coupled receptor 142(Human)
Lilly China Research and Development Center (Lcrdc)

Curated by ChEMBL
LigandPNGBDBM50544792(CHEMBL4646115)
Affinity DataEC50:  63nMAssay Description:Agonist activity at human GPR142 receptor expressed in HEK293 cells assessed as accumulation of inositol phosphate incubated for 1 hr followed by IP1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProbable G-protein coupled receptor 142(Human)
Lilly China Research and Development Center (Lcrdc)

Curated by ChEMBL
LigandPNGBDBM50544793(CHEMBL4649204)
Affinity DataEC50:  81nMAssay Description:Agonist activity at human GPR142 receptor expressed in HEK293 cells assessed as accumulation of inositol phosphate incubated for 1 hr followed by IP1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProbable G-protein coupled receptor 142(Human)
Lilly China Research and Development Center (Lcrdc)

Curated by ChEMBL
LigandPNGBDBM50544794(CHEMBL4633342)
Affinity DataEC50:  93nMAssay Description:Agonist activity at human GPR142 receptor expressed in HEK293 cells assessed as accumulation of inositol phosphate incubated for 1 hr followed by IP1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProbable G-protein coupled receptor 142(Human)
Lilly China Research and Development Center (Lcrdc)

Curated by ChEMBL
LigandPNGBDBM50544795(CHEMBL4636254)
Affinity DataEC50:  147nMAssay Description:Agonist activity at human GPR142 receptor expressed in HEK293 cells assessed as accumulation of inositol phosphate incubated for 1 hr followed by IP1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProbable G-protein coupled receptor 142(Human)
Lilly China Research and Development Center (Lcrdc)

Curated by ChEMBL
LigandPNGBDBM50544796(CHEMBL4641543)
Affinity DataEC50:  51nMAssay Description:Agonist activity at human GPR142 receptor expressed in HEK293 cells assessed as accumulation of inositol phosphate incubated for 1 hr followed by IP1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProbable G-protein coupled receptor 142(Human)
Lilly China Research and Development Center (Lcrdc)

Curated by ChEMBL
LigandPNGBDBM50544797(CHEMBL4644869)
Affinity DataEC50:  71nMAssay Description:Agonist activity at human GPR142 receptor expressed in HEK293 cells assessed as accumulation of inositol phosphate incubated for 1 hr followed by IP1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProbable G-protein coupled receptor 142(Human)
Lilly China Research and Development Center (Lcrdc)

Curated by ChEMBL
LigandPNGBDBM50544798(CHEMBL4641254)
Affinity DataEC50:  110nMAssay Description:Agonist activity at human GPR142 receptor expressed in HEK293 cells assessed as accumulation of inositol phosphate incubated for 1 hr followed by IP1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProbable G-protein coupled receptor 142(Human)
Lilly China Research and Development Center (Lcrdc)

Curated by ChEMBL
LigandPNGBDBM50544799(CHEMBL4637087)
Affinity DataEC50:  104nMAssay Description:Agonist activity at human GPR142 receptor expressed in HEK293 cells assessed as accumulation of inositol phosphate incubated for 1 hr followed by IP1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProbable G-protein coupled receptor 142(Human)
Lilly China Research and Development Center (Lcrdc)

Curated by ChEMBL
LigandPNGBDBM50544800(CHEMBL4647745)
Affinity DataEC50:  11nMAssay Description:Agonist activity at human GPR142 receptor expressed in HEK293 cells assessed as accumulation of inositol phosphate incubated for 1 hr followed by IP1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProbable G-protein coupled receptor 142(Human)
Lilly China Research and Development Center (Lcrdc)

Curated by ChEMBL
LigandPNGBDBM50544801(CHEMBL4647456)
Affinity DataEC50:  14nMAssay Description:Agonist activity at human GPR142 receptor expressed in HEK293 cells assessed as accumulation of inositol phosphate incubated for 1 hr followed by IP1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProbable G-protein coupled receptor 142(Human)
Lilly China Research and Development Center (Lcrdc)

Curated by ChEMBL
LigandPNGBDBM50544802(CHEMBL4644081)
Affinity DataEC50:  76nMAssay Description:Agonist activity at human GPR142 receptor expressed in HEK293 cells assessed as accumulation of inositol phosphate incubated for 1 hr followed by IP1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProbable G-protein coupled receptor 142(Human)
Lilly China Research and Development Center (Lcrdc)

Curated by ChEMBL
LigandPNGBDBM50544803(CHEMBL4642312)
Affinity DataEC50:  41nMAssay Description:Agonist activity at human GPR142 receptor expressed in HEK293 cells assessed as accumulation of inositol phosphate incubated for 1 hr followed by IP1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProbable G-protein coupled receptor 142(Human)
Lilly China Research and Development Center (Lcrdc)

Curated by ChEMBL
LigandPNGBDBM332762(US10196385, Example 1 | Cis-(chiral)-N-[(2-[5-(1,4...)
Affinity DataEC50:  43nMAssay Description:Agonist activity at human GPR142 receptor expressed in HEK293 cells assessed as accumulation of inositol phosphate incubated for 1 hr followed by IP1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProbable G-protein coupled receptor 142(Human)
Lilly China Research and Development Center (Lcrdc)

Curated by ChEMBL
LigandPNGBDBM332763(US10196385, Example 2 | Cis-(chiral)-N-[2-[5-(1,4-...)
Affinity DataEC50:  30nMAssay Description:Agonist activity at human GPR142 receptor expressed in HEK293 cells assessed as accumulation of inositol phosphate incubated for 1 hr followed by IP1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProbable G-protein coupled receptor 142(Human)
Lilly China Research and Development Center (Lcrdc)

Curated by ChEMBL
LigandPNGBDBM332764(US10196385, Example 3 | Cis-(chiral)-3-Chloro-N-[2...)
Affinity DataEC50:  27nMAssay Description:Agonist activity at human GPR142 receptor expressed in HEK293 cells assessed as accumulation of inositol phosphate incubated for 1 hr followed by IP1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProbable G-protein coupled receptor 142(Human)
Lilly China Research and Development Center (Lcrdc)

Curated by ChEMBL
LigandPNGBDBM50544804(CHEMBL4637374)
Affinity DataEC50:  16nMAssay Description:Agonist activity at human GPR142 receptor expressed in HEK293 cells assessed as accumulation of inositol phosphate incubated for 1 hr followed by IP1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProbable G-protein coupled receptor 142(Human)
Lilly China Research and Development Center (Lcrdc)

Curated by ChEMBL
LigandPNGBDBM50544805(CHEMBL4646017)
Affinity DataEC50:  14nMAssay Description:Agonist activity at human GPR142 receptor expressed in HEK293 cells assessed as accumulation of inositol phosphate incubated for 1 hr followed by IP1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProbable G-protein coupled receptor 142(Human)
Lilly China Research and Development Center (Lcrdc)

Curated by ChEMBL
LigandPNGBDBM50544806(CHEMBL4639333)
Affinity DataEC50:  46nMAssay Description:Agonist activity at human GPR142 receptor expressed in HEK293 cells assessed as accumulation of inositol phosphate incubated for 1 hr followed by IP1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProbable G-protein coupled receptor 142(Human)
Lilly China Research and Development Center (Lcrdc)

Curated by ChEMBL
LigandPNGBDBM50544807(CHEMBL4641575)
Affinity DataEC50:  32nMAssay Description:Agonist activity at human GPR142 receptor expressed in HEK293 cells assessed as accumulation of inositol phosphate incubated for 1 hr followed by IP1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProbable G-protein coupled receptor 142(Human)
Lilly China Research and Development Center (Lcrdc)

Curated by ChEMBL
LigandPNGBDBM50544808(CHEMBL4644313)
Affinity DataEC50:  53nMAssay Description:Agonist activity at human GPR142 receptor expressed in HEK293 cells assessed as accumulation of inositol phosphate incubated for 1 hr followed by IP1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProbable G-protein coupled receptor 142(Human)
Lilly China Research and Development Center (Lcrdc)

Curated by ChEMBL
LigandPNGBDBM50544809(CHEMBL4632719)
Affinity DataEC50:  102nMAssay Description:Agonist activity at human GPR142 receptor expressed in HEK293 cells assessed as accumulation of inositol phosphate incubated for 1 hr followed by IP1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProbable G-protein coupled receptor 142(Human)
Lilly China Research and Development Center (Lcrdc)

Curated by ChEMBL
LigandPNGBDBM50544810(CHEMBL4641984)
Affinity DataEC50:  35nMAssay Description:Agonist activity at human GPR142 receptor expressed in HEK293 cells assessed as accumulation of inositol phosphate incubated for 1 hr followed by IP1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGlucocorticoid receptor(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50550121(CHEMBL4787613)
Affinity DataKd:  2.20nMAssay Description:Induction of translocation of human glucocorticoid receptor expressed in HEK293T cells transduced with lentiviral vector expressing H2B-mCherry and G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGlucocorticoid receptor(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50550122(CHEMBL4754182)
Affinity DataKd:  138nMAssay Description:Induction of translocation of human glucocorticoid receptor expressed in HEK293T cells transduced with lentiviral vector expressing H2B-mCherry and G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGlucocorticoid receptor(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50550123(CHEMBL4755113)
Affinity DataKd:  883nMAssay Description:Induction of translocation of human glucocorticoid receptor expressed in HEK293T cells transduced with lentiviral vector expressing H2B-mCherry and G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
Displayed 1 to 50 (of 3955 total ) | Next | Last >>
Jump to: