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Found 94 with Last Name = 'tibbitts' and Initial = 'tt'
TargetTransient receptor potential protein 5(Rattus norvegicus)
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529421(CHEMBL4530872)
Affinity DataIC50:  180nMAssay Description:Inhibition of rosiglitazone-activated rat TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with holdi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529421(CHEMBL4530872)
Affinity DataIC50:  180nMAssay Description:Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529421(CHEMBL4530872)
Affinity DataIC50:  280nMAssay Description:Inhibition of human TRPC5 channel expressed in HEK293 cells assessed as decrease in current amplitude treated for 3 mins measured between +80 mV and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 4(Homo sapiens)
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529421(CHEMBL4530872)
Affinity DataIC50:  290nMAssay Description:Inhibition of Englerin-activated human TRPC4 channel expressed in HEK293 cells by Q-patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529418(CHEMBL4452948)
Affinity DataIC50:  380nMAssay Description:Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529427(CHEMBL4536108)
Affinity DataIC50:  490nMAssay Description:Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529454(CHEMBL4440201)
Affinity DataIC50:  500nMAssay Description:Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529447(CHEMBL4517031)
Affinity DataIC50:  530nMAssay Description:Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529426(CHEMBL4475970)
Affinity DataIC50:  530nMAssay Description:Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529449(CHEMBL4449727)
Affinity DataIC50:  650nMAssay Description:Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529450(CHEMBL4563968)
Affinity DataIC50:  650nMAssay Description:Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529430(CHEMBL4551777)
Affinity DataIC50:  660nMAssay Description:Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529452(CHEMBL4458885)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529440(CHEMBL4467989)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529444(CHEMBL4473064)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529419(CHEMBL4434976)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529420(CHEMBL4546342)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529445(CHEMBL4471419)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529422(CHEMBL4447753)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of (-)-Englerin-activated human TRPC5 channel expressed in HEK293 cells measured at holding potential of -60 mV by Q-patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529422(CHEMBL4447753)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of lanthanum-activated human TRPC5 channel expressed in HEK293 cells measured at holding potential of -60 mV by Q-patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529422(CHEMBL4447753)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529422(CHEMBL4447753)
Affinity DataIC50:  7.80E+3nMAssay Description:Inhibition of riluzole-activated human TRPC5 channel expressed in HEK293 cells measured at holding potential of -60 mV by Q-patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529457(CHEMBL4474451)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529442(CHEMBL4458766)
Affinity DataIC50:  8.20E+3nMAssay Description:Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529421(CHEMBL4530872)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of human ERG stably expressed in HEK293 cells measured at holding potential of -90 mV by manual patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529441(CHEMBL4592027)
Affinity DataIC50:  8.80E+3nMAssay Description:Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529443(CHEMBL4442703)
Affinity DataIC50:  9.60E+3nMAssay Description:Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529432(CHEMBL4473219)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529424(CHEMBL4436613)
Affinity DataIC50:  1.12E+4nMAssay Description:Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529428(CHEMBL4470341)
Affinity DataIC50:  1.45E+4nMAssay Description:Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529455(CHEMBL4542897)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529456(CHEMBL4524687)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529435(CHEMBL4594091)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529438(CHEMBL4528028)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529433(CHEMBL4565194)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 6(Homo sapiens (Human))
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529421(CHEMBL4530872)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of OAG-activated human TRPC6 channel expressed in HEK293 cells by Q-patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529421(CHEMBL4530872)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human Nav1.5 stably expressed in CHO cells measured at holding potential of -80 mV by manual patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529423(CHEMBL4454366)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529425(CHEMBL4475647)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529429(CHEMBL4439131)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529431(CHEMBL4547350)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529434(CHEMBL4518299)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529436(CHEMBL4556467)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529437(CHEMBL4448384)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529439(CHEMBL4590831)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529446(CHEMBL4436512)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 6(Homo sapiens (Human))
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529422(CHEMBL4447753)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of OAG-activated human TRPC6 channel expressed in HEK293 cells by Q-patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529448(CHEMBL4568038)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529451(CHEMBL4469449)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529453(CHEMBL4454641)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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