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TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50462627(CHEMBL1958308)
Affinity DataKd:  21nMAssay Description:Binding affinity to recombinant human N-terminal His-tagged TNKS2 (Ser959 to Gly1166 residues) expressed in Escherichia coli by surface plasmon reson...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50462627(CHEMBL1958308)
Affinity DataKd:  520nMAssay Description:Binding affinity to recombinant human N-terminal GSt-tagged TNKS1 (1000 to 1328 residues) expressed in baculovirus infected Sf9 cells by surface plas...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCasein kinase II subunit alpha/beta(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM11323(CHEMBL177820 | 4,5,6,7-tetrabromo-1H-1,2,3-benzotr...)
Affinity DataKd:  790nMAssay Description:Binding affinity to recombinant human CK2alpha/beta expressed in Escherichia coli by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50188594(CHEMBL1086580 | CHEBI:62878 | US20240279201, Compo...)
Affinity DataKd:  4.20nMAssay Description:Binding affinity to recombinant human N-terminal His-tagged TNKS2 (Ser959 to Gly1166 residues) expressed in Escherichia coli by surface plasmon reson...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50462628(CHEMBL4239155)
Affinity DataKd:  6.5nMAssay Description:Binding affinity to recombinant human N-terminal His-tagged TNKS2 (Ser959 to Gly1166 residues) expressed in Escherichia coli by surface plasmon reson...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50462626(CHEMBL4127893)
Affinity DataKd:  1.25E+3nMAssay Description:Binding affinity to recombinant human PARP1 expressed in baculovirus infected Sf9 cells by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50462629(CHEMBL3594248)
Affinity DataKd:  19nMAssay Description:Binding affinity to recombinant human N-terminal His-tagged TNKS2 (Ser959 to Gly1166 residues) expressed in Escherichia coli by surface plasmon reson...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50462626(CHEMBL4127893)
Affinity DataKd:  5.26E+3nMAssay Description:Binding affinity to recombinant human N-terminal GSt-tagged TNKS1 (1000 to 1328 residues) expressed in baculovirus infected Sf9 cells by surface plas...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50483783(CHEMBL1770433)
Affinity DataIC50: 480nMAssay Description:Inhibition of PKC activation in PMA-treated human fibroblasts assessed as inhibition of translocation to plasma membrane cells pretreated for 1 hr fo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50140689(CHEMBL3752809)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of PGES-1 in IL-1beta stimulated human A549 cell microsomes using PGH2 as substrate assessed as suppression of PGE2 formation preincubated...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50006805(CHEMBL29097 | 3-(3-(tert-butylthio)-1-(4-chloroben...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of PGES-1 in IL-1beta stimulated human A549 cell microsomes using PGH2 as substrate assessed as suppression of PGE2 formation preincubated...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50140689(CHEMBL3752809)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of PGES-1 in IL-1beta stimulated human A549 cell microsomes using PGH2 as substrate assessed as suppression of PGE2 formation preincubated...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50140688(CHEMBL3754377)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of PGES-1 in IL-1beta stimulated human A549 cell microsomes using PGH2 as substrate assessed as suppression of PGE2 formation preincubated...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50140690(CHEMBL3752963)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of PGES-1 in IL-1beta stimulated human A549 cell microsomes using PGH2 as substrate assessed as suppression of PGE2 formation preincubated...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50140687(CHEMBL3752388)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of PGES-1 in IL-1beta stimulated human A549 cell microsomes using PGH2 as substrate assessed as suppression of PGE2 formation preincubated...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50140686(CHEMBL538661)
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of PGES-1 in IL-1beta stimulated human A549 cell microsomes using PGH2 as substrate assessed as suppression of PGE2 formation preincubated...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-galactosidase(Yellow koji mold)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50499768(CHEMBL3740658)
Affinity DataIC50: 2.58E+5nMAssay Description:Inhibition of Aspergillus oryzae beta-galactosidase using oNP-beta-Gal as substrate assessed as release of o-nitrophenol incubated for 30 mins by spe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-galactosidase(Yellow koji mold)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50499767(CHEMBL3741440)
Affinity DataIC50: 2.96E+5nMAssay Description:Inhibition of Aspergillus oryzae beta-galactosidase using oNP-beta-Gal as substrate assessed as release of o-nitrophenol incubated for 30 mins by spe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-galactosidase(Yellow koji mold)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50499771(CHEMBL3740283)
Affinity DataIC50: 2.97E+5nMAssay Description:Inhibition of Aspergillus oryzae beta-galactosidase using oNP-beta-Gal as substrate assessed as release of o-nitrophenol incubated for 30 mins by spe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-galactosidase(Yellow koji mold)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50499769(CHEMBL3739825)
Affinity DataIC50: 2.98E+5nMAssay Description:Inhibition of Aspergillus oryzae beta-galactosidase using oNP-beta-Gal as substrate assessed as release of o-nitrophenol incubated for 30 mins by spe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-galactosidase(Yellow koji mold)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50499770(CHEMBL3742045)
Affinity DataIC50: 2.99E+5nMAssay Description:Inhibition of Aspergillus oryzae beta-galactosidase using oNP-beta-Gal as substrate assessed as release of o-nitrophenol incubated for 30 mins by spe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSialidase-2(Human)
Pf-Imss-Kek-Sbrc, Ibaraki 305-0801, Japan.

Curated by ChEMBL
LigandPNGBDBM50330326((4S,5R,6R)-5-Acetylamino-4-guanidino-6-((1R,3R)-1,...)
Affinity DataKi:  1.70E+4nMAssay Description:Inhibition of human neuraminidase 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSialidase-2(Human)
Pf-Imss-Kek-Sbrc, Ibaraki 305-0801, Japan.

Curated by ChEMBL
LigandPNGBDBM4706(2,3-didehydro-2-deoxy-N-acetylneuraminic acid | (2...)
Affinity DataKi:  1.40E+5nMAssay Description:Inhibition of human neuraminidase 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSialidase-2(Human)
Pf-Imss-Kek-Sbrc, Ibaraki 305-0801, Japan.

Curated by ChEMBL
LigandPNGBDBM5024((-)-(1S,2S,3R,4R)-3-[(1S)-1-(Acetylamino)-2-ethylb...)
Affinity DataKi:  3.30E+5nMAssay Description:Inhibition of human neuraminidase 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSialidase-2(Human)
Pf-Imss-Kek-Sbrc, Ibaraki 305-0801, Japan.

Curated by ChEMBL
LigandPNGBDBM50314987((2S,3R,4R)-3-acetamido-4-hydroxy-2-(3-hydroxypropo...)
Affinity DataKi:  7.40E+5nMAssay Description:Inhibition of human neuraminidase 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSialidase-2(Human)
Pf-Imss-Kek-Sbrc, Ibaraki 305-0801, Japan.

Curated by ChEMBL
LigandPNGBDBM50314988((2S,3R,4R)-3-acetamido-4-hydroxy-2-isobutoxy-3,4-d...)
Affinity DataKi:  8.80E+5nMAssay Description:Inhibition of human neuraminidase 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSialidase-2(Human)
Pf-Imss-Kek-Sbrc, Ibaraki 305-0801, Japan.

Curated by ChEMBL
LigandPNGBDBM50314986((2S,3R,4R)-3-acetamido-2-(2,3-dihydroxypropoxy)-4-...)
Affinity DataKi:  1.40E+6nMAssay Description:Inhibition of human neuraminidase 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed