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TargetNitric oxide synthase, brain(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50062142(4,6-Dimethyl-piperidin-(2Z)-ylideneamine | CHEMBL2...)
Affinity DataIC50: 60nMAssay Description:Inhibition of human Neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50062142(4,6-Dimethyl-piperidin-(2Z)-ylideneamine | CHEMBL2...)
Affinity DataIC50: 80nMAssay Description:Inhibition of human Inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50062133(4-Methyl-piperidin-(2Z)-ylideneamine | 4-Methyl-pi...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human Inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50064015(7-Propyl-azepan-(2Z)-ylideneamine; hydrochloride |...)
Affinity DataIC50: 160nMAssay Description:Inhibitory activity evaluated for soluble cell extract of human Inducible nitric oxide synthase and partially purified by DEAE-sepharose chromatograp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50064018(7-Allyl-azepan-(2Z)-ylideneamine; hydrochloride | ...)
Affinity DataIC50: 190nMAssay Description:Inhibitory activity evaluated for soluble cell extract of human Inducible nitric oxide synthase and partially purified by DEAE-sepharose chromatograp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50062132(6-Propyl-piperidin-(2Z)-ylideneamine | CHEMBL6760)
Affinity DataIC50: 200nMAssay Description:Inhibition of human Inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50062133(4-Methyl-piperidin-(2Z)-ylideneamine | 4-Methyl-pi...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human Neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50062142(4,6-Dimethyl-piperidin-(2Z)-ylideneamine | CHEMBL2...)
Affinity DataIC50: 300nMAssay Description:inhibition of human endothelial constitutive Endothelial nitric oxide synthase (heNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50062137(6-Methyl-piperidin-(2Z)-ylideneamine | CHEMBL26567...)
Affinity DataIC50: 400nMAssay Description:Inhibition of human Neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50064015(7-Propyl-azepan-(2Z)-ylideneamine; hydrochloride |...)
Affinity DataIC50: 460nMAssay Description:Inhibitory activity evaluated from soluble cell extract of human Neuronal nitric oxide synthase and partially purified by DEAE-sepharose chromatograp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50062131(6-Trifluoromethyl-piperidin-(2Z)-ylideneamine | CH...)
Affinity DataIC50: 500nMAssay Description:Inhibition of human Neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50064011(CHEMBL543514 | CHEMBL89288 | 7-Butyl-azepan-(2Z)-y...)
Affinity DataIC50: 500nMAssay Description:Inhibitory activity evaluated for soluble cell extract of human Inducible nitric oxide synthase and partially purified by DEAE-sepharose chromatograp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50062137(6-Methyl-piperidin-(2Z)-ylideneamine | CHEMBL26567...)
Affinity DataIC50: 500nMAssay Description:Inhibition of human Inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50062132(6-Propyl-piperidin-(2Z)-ylideneamine | CHEMBL6760)
Affinity DataIC50: 500nMAssay Description:Inhibition of human Neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50062131(6-Trifluoromethyl-piperidin-(2Z)-ylideneamine | CH...)
Affinity DataIC50: 500nMAssay Description:Inhibition of human Inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50064015(7-Propyl-azepan-(2Z)-ylideneamine; hydrochloride |...)
Affinity DataIC50: 600nMAssay Description:The ability of compound to inhibit mouse Inducible nitric oxide synthase in LPS stimulated mouse RAW cells was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50062137(6-Methyl-piperidin-(2Z)-ylideneamine | CHEMBL26567...)
Affinity DataIC50: 600nMAssay Description:inhibition of human endothelial constitutive Endothelial nitric oxide synthase (heNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50064018(7-Allyl-azepan-(2Z)-ylideneamine; hydrochloride | ...)
Affinity DataIC50: 600nMAssay Description:The ability of compound to inhibit mouse Inducible nitric oxide synthase in LPS stimulated mouse RAW cells was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50062145(3-Methyl-piperidin-(2Z)-ylideneamine | CHEMBL26716...)
Affinity DataIC50: 700nMAssay Description:Inhibition of human Neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50064011(CHEMBL543514 | CHEMBL89288 | 7-Butyl-azepan-(2Z)-y...)
Affinity DataIC50: 850nMAssay Description:Inhibitory activity evaluated from soluble cell extract of human nNeuronal nitric oxide synthase and partially purified by DEAE-sepharose chromatogra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50064018(7-Allyl-azepan-(2Z)-ylideneamine; hydrochloride | ...)
Affinity DataIC50: 870nMAssay Description:Inhibitory activity evaluated from soluble cell extract of human Neuronal nitric oxide synthase and partially purified by DEAE-sepharose chromatograp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50062136(6-Benzyl-piperidin-(2Z)-ylideneamine | CHEMBL6875)
Affinity DataIC50: 900nMAssay Description:Inhibition of human Neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50049255(Piperidin-(2E)-ylideneamine | Piperidin-(2Z)-ylide...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human Neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50049255(Piperidin-(2E)-ylideneamine | Piperidin-(2Z)-ylide...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human Inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50062133(4-Methyl-piperidin-(2Z)-ylideneamine | 4-Methyl-pi...)
Affinity DataIC50: 1.10E+3nMAssay Description:inhibition of human endothelial constitutive Endothelial nitric oxide synthase (heNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50064010(3-Ethyl-azepan-(2Z)-ylideneamine; hydrochloride | ...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibitory activity evaluated for soluble cell extract of human Inducible nitric oxide synthase and partially purified by DEAE-sepharose chromatograp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50062135(4-Ethyl-piperidin-(2Z)-ylideneamine | CHEMBL6813)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human Neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50064011(CHEMBL543514 | CHEMBL89288 | 7-Butyl-azepan-(2Z)-y...)
Affinity DataIC50: 1.60E+3nMAssay Description:The ability of compound to inhibit mouse Inducible nitric oxide synthase in LPS stimulated mouse RAW cells was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50062131(6-Trifluoromethyl-piperidin-(2Z)-ylideneamine | CH...)
Affinity DataIC50: 2.00E+3nMAssay Description:inhibition of human endothelial constitutive Endothelial nitric oxide synthase (heNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50049257(CHEMBL543752 | CHEMBL315857 | Azepan-(2Z)-ylidenea...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibitory activity evaluated for soluble cell extract of human Inducible nitric oxide synthase and partially purified by DEAE-sepharose chromatograp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50064013(7-(2-Ethyl-butyl)-azepan-(2Z)-ylideneamine; hydroc...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibitory activity evaluated for soluble cell extract of human Inducible nitric oxide synthase and partially purified by DEAE-sepharose chromatograp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50062132(6-Propyl-piperidin-(2Z)-ylideneamine | CHEMBL6760)
Affinity DataIC50: 2.20E+3nMAssay Description:inhibition of human endothelial constitutive Endothelial nitric oxide synthase (heNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50064010(3-Ethyl-azepan-(2Z)-ylideneamine; hydrochloride | ...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibitory activity evaluated from soluble cell extract of Neuronal nitric oxide synthase and partially purified by DEAE-sepharose chromatographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50062135(4-Ethyl-piperidin-(2Z)-ylideneamine | CHEMBL6813)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human Inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50062145(3-Methyl-piperidin-(2Z)-ylideneamine | CHEMBL26716...)
Affinity DataIC50: 3.00E+3nMAssay Description:inhibition of human endothelial constitutive Endothelial nitric oxide synthase (heNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50062138(4-Trifluoromethyl-piperidin-(2Z)-ylideneamine | CH...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of human Inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50064013(7-(2-Ethyl-butyl)-azepan-(2Z)-ylideneamine; hydroc...)
Affinity DataIC50: 3.30E+3nMAssay Description:The ability of compound to inhibit mouse Inducible nitric oxide synthase in LPS stimulated mouse RAW cells was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50062138(4-Trifluoromethyl-piperidin-(2Z)-ylideneamine | CH...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human Neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50062140(4,4-Dimethyl-piperidin-(2Z)-ylideneamine | CHEMBL6...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of human Inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50064010(3-Ethyl-azepan-(2Z)-ylideneamine; hydrochloride | ...)
Affinity DataIC50: 3.50E+3nMAssay Description:The ability of compound to inhibit mouse Inducible nitric oxide synthase in LPS stimulated mouse RAW cells was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50049257(CHEMBL543752 | CHEMBL315857 | Azepan-(2Z)-ylidenea...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibitory activity evaluated from soluble cell extract of human Neuronal nitric oxide synthase and partially purified by DEAE-sepharose chromatograp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50064014((R)-6-Methyl-azepan-(2Z)-ylideneamine; hydrochlori...)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibitory activity evaluated from soluble cell extract of human nNeuronal nitric oxide synthase and partially purified by DEAE-sepharose chromatogra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50062139(5-Methyl-piperidin-(2Z)-ylideneamine | CHEMBL26933...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of human Neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50049255(Piperidin-(2E)-ylideneamine | Piperidin-(2Z)-ylide...)
Affinity DataIC50: 4.70E+3nMAssay Description:inhibition of human endothelial constitutive Endothelial nitric oxide synthase (heNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50062139(5-Methyl-piperidin-(2Z)-ylideneamine | CHEMBL26933...)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of human Inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50062140(4,4-Dimethyl-piperidin-(2Z)-ylideneamine | CHEMBL6...)
Affinity DataIC50: 5.30E+3nMAssay Description:inhibition of human endothelial constitutive Endothelial nitric oxide synthase (heNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50062143(6-Cyclohexyl-piperidin-(2Z)-ylideneamine | CHEMBL7...)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of human Neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50064013(7-(2-Ethyl-butyl)-azepan-(2Z)-ylideneamine; hydroc...)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibitory activity evaluated from soluble cell extract of human Neuronal nitric oxide synthase and partially purified by DEAE-sepharose chromatograp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50064019(5-Methyl-azepan-(2Z)-ylideneamine; hydrochloride |...)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibitory activity evaluated for soluble cell extract of human Inducible nitric oxide synthase and partially purified by DEAE-sepharose chromatograp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50064012(3-Allyl-azepan-(2Z)-ylideneamine; hydrochloride | ...)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibitory activity evaluated for soluble cell extract of human Inducible nitric oxide synthase and partially purified by DEAE-sepharose chromatograp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
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