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TargetThromboxane A2 receptor(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50353634(CHEMBL1828642)
Affinity DataKd: >1.00E+4nMAssay Description:Displacement of [3H]SQ-29548 from human prostanoid TP receptor expressed in QBI-HEK 293A cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane A2 receptor(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50353635(CHEMBL1829801)
Affinity DataKd:  331nMAssay Description:Displacement of [3H]SQ-29548 from human prostanoid TP receptor expressed in QBI-HEK 293A cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane A2 receptor(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50353636(CHEMBL1829802)
Affinity DataKd:  359nMAssay Description:Displacement of [3H]SQ-29548 from human prostanoid TP receptor expressed in QBI-HEK 293A cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane A2 receptor(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50353637(CHEMBL1829803)
Affinity DataKd:  1.14E+4nMAssay Description:Displacement of [3H]SQ-29548 from human prostanoid TP receptor expressed in QBI-HEK 293A cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane A2 receptor(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50353638(CHEMBL1829805)
Affinity DataKd:  203nMAssay Description:Displacement of [3H]SQ-29548 from human prostanoid TP receptor expressed in QBI-HEK 293A cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane A2 receptor(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50353639(CHEMBL1829806)
Affinity DataKd:  328nMAssay Description:Displacement of [3H]SQ-29548 from human prostanoid TP receptor expressed in QBI-HEK 293A cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane A2 receptor(Mouse)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50353640(CHEMBL65121)
Affinity DataKd:  26nMAssay Description:Displacement of [3H]SQ-29548 from mouse prostanoid TP receptor expressed in QBI-HEK 293A cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane A2 receptor(Mouse)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50353634(CHEMBL1828642)
Affinity DataKd:  1.00E+4nMAssay Description:Displacement of [3H]SQ-29548 from mouse prostanoid TP receptor expressed in QBI-HEK 293A cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane A2 receptor(Mouse)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50353635(CHEMBL1829801)
Affinity DataKd:  19nMAssay Description:Displacement of [3H]SQ-29548 from mouse prostanoid TP receptor expressed in QBI-HEK 293A cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane A2 receptor(Mouse)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50353636(CHEMBL1829802)
Affinity DataKd:  17nMAssay Description:Displacement of [3H]SQ-29548 from mouse prostanoid TP receptor expressed in QBI-HEK 293A cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane A2 receptor(Mouse)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50353637(CHEMBL1829803)
Affinity DataKd:  1.20E+3nMAssay Description:Displacement of [3H]SQ-29548 from mouse prostanoid TP receptor expressed in QBI-HEK 293A cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane A2 receptor(Mouse)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50353638(CHEMBL1829805)
Affinity DataKd:  11nMAssay Description:Displacement of [3H]SQ-29548 from mouse prostanoid TP receptor expressed in QBI-HEK 293A cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane A2 receptor(Mouse)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50353639(CHEMBL1829806)
Affinity DataKd:  26nMAssay Description:Displacement of [3H]SQ-29548 from mouse prostanoid TP receptor expressed in QBI-HEK 293A cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane A2 receptor(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50353640(CHEMBL65121)
Affinity DataKd:  141nMAssay Description:Displacement of [3H]SQ-29548 from human prostanoid TP receptor expressed in QBI-HEK 293A cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane A2 receptor(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50026750(CHEMBL3354618)
Affinity DataIC50: 0.0150nMAssay Description:Antagonist activity against human thromboxane A2 receptor alpha expressed in QBI-HEK293A cells assessed as reduction in I-BOP-induced inositol monoph...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane A2 receptor(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50026748(CHEMBL3354616)
Affinity DataIC50: 0.0520nMAssay Description:Antagonist activity against human thromboxane A2 receptor alpha expressed in QBI-HEK293A cells assessed as reduction in I-BOP-induced inositol monoph...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane A2 receptor(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50058027(CHEMBL29374)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human TP receptor expressed in QBI-HEK 293A cells assessed as IP3 metabolite level after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane A2 receptor(Mouse)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50353639(CHEMBL1829806)
Affinity DataIC50: 3.10nMAssay Description:Antagonist activity at mouse prostanoid TP receptor expressed in QBI-HEK 293A cells assessed as inhibition of 1-BOP-induced increase in inositol mono...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane A2 receptor(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50026760(CHEMBL3354614)
Affinity DataIC50: 3.90nMAssay Description:Antagonist activity against human thromboxane A2 receptor alpha expressed in QBI-HEK293A cells assessed as reduction in I-BOP-induced inositol monoph...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane A2 receptor(Mouse)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50353632(CHEMBL1829812)
Affinity DataIC50: 5.80nMAssay Description:Antagonist activity at mouse prostanoid TP receptor expressed in QBI-HEK 293A cells assessed as inhibition of 1-BOP-induced increase in inositol mono...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane A2 receptor(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50026761(CHEMBL3354615)
Affinity DataIC50: 6.5nMAssay Description:Antagonist activity against human thromboxane A2 receptor alpha expressed in QBI-HEK293A cells assessed as reduction in I-BOP-induced inositol monoph...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane A2 receptor(Mouse)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50353635(CHEMBL1829801)
Affinity DataIC50: 8nMAssay Description:Antagonist activity at mouse prostanoid TP receptor expressed in QBI-HEK 293A cells assessed as inhibition of 1-BOP-induced increase in inositol mono...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane A2 receptor(Mouse)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50353643(CHEMBL1829808)
Affinity DataIC50: 9.40nMAssay Description:Antagonist activity at mouse prostanoid TP receptor expressed in QBI-HEK 293A cells assessed as inhibition of 1-BOP-induced increase in inositol mono...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane A2 receptor(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50026758(CHEMBL3335473)
Affinity DataIC50: 11nMAssay Description:Antagonist activity against human thromboxane A2 receptor alpha expressed in QBI-HEK293A cells assessed as reduction in I-BOP-induced inositol monoph...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane A2 receptor(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50026759(CHEMBL3354613)
Affinity DataIC50: 11nMAssay Description:Antagonist activity against human thromboxane A2 receptor alpha expressed in QBI-HEK293A cells assessed as reduction in I-BOP-induced inositol monoph...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane A2 receptor(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50026753(S-18886 | Terutroban)
Affinity DataIC50: 16nMAssay Description:Antagonist activity against human thromboxane A2 receptor alpha expressed in QBI-HEK293A cells assessed as reduction in I-BOP-induced inositol monoph...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane A2 receptor(Mouse)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50353645(CHEMBL1829810)
Affinity DataIC50: 18nMAssay Description:Antagonist activity at mouse prostanoid TP receptor expressed in QBI-HEK 293A cells assessed as inhibition of 1-BOP-induced increase in inositol mono...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane A2 receptor(Mouse)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50353640(CHEMBL65121)
Affinity DataIC50: 27nMAssay Description:Antagonist activity at mouse prostanoid TP receptor expressed in QBI-HEK 293A cells assessed as inhibition of 1-BOP-induced increase in inositol mono...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane A2 receptor(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50026751(CHEMBL3354619)
Affinity DataIC50: 29nMAssay Description:Antagonist activity against human thromboxane A2 receptor alpha expressed in QBI-HEK293A cells assessed as reduction in I-BOP-induced inositol monoph...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane A2 receptor(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50353632(CHEMBL1829812)
Affinity DataIC50: 41nMAssay Description:Antagonist activity at human prostanoid TP receptor expressed in QBI-HEK 293A cells assessed as inhibition of 1-BOP-induced increase in inositol mono...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane A2 receptor(Mouse)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50353638(CHEMBL1829805)
Affinity DataIC50: 52nMAssay Description:Antagonist activity at mouse prostanoid TP receptor expressed in QBI-HEK 293A cells assessed as inhibition of 1-BOP-induced increase in inositol mono...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane A2 receptor(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50058026(CHEMBL3326602)
Affinity DataIC50: 54nMAssay Description:Inhibition of human TP receptor expressed in QBI-HEK 293A cells assessed as IP3 metabolite level after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane A2 receptor(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50026755(CHEMBL3335482)
Affinity DataIC50: 59nMAssay Description:Antagonist activity against human thromboxane A2 receptor alpha expressed in QBI-HEK293A cells assessed as reduction in I-BOP-induced inositol monoph...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane A2 receptor(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50353640(CHEMBL65121)
Affinity DataIC50: 61nMAssay Description:Antagonist activity at human prostanoid TP receptor expressed in QBI-HEK 293A cells assessed as inhibition of 1-BOP-induced increase in inositol mono...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane A2 receptor(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50353635(CHEMBL1829801)
Affinity DataIC50: 64nMAssay Description:Antagonist activity at human prostanoid TP receptor expressed in QBI-HEK 293A cells assessed as inhibition of 1-BOP-induced increase in inositol mono...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane A2 receptor(Mouse)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50353636(CHEMBL1829802)
Affinity DataIC50: 91nMAssay Description:Antagonist activity at mouse prostanoid TP receptor expressed in QBI-HEK 293A cells assessed as inhibition of 1-BOP-induced increase in inositol mono...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane A2 receptor(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50353639(CHEMBL1829806)
Affinity DataIC50: 131nMAssay Description:Antagonist activity at human prostanoid TP receptor expressed in QBI-HEK 293A cells assessed as inhibition of 1-BOP-induced increase in inositol mono...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane A2 receptor(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50353643(CHEMBL1829808)
Affinity DataIC50: 171nMAssay Description:Antagonist activity at human prostanoid TP receptor expressed in QBI-HEK 293A cells assessed as inhibition of 1-BOP-induced increase in inositol mono...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane A2 receptor(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50353640(CHEMBL65121)
Affinity DataIC50: 190nMAssay Description:Inhibition of human TP receptor expressed in QBI-HEK 293A cells assessed as IP3 metabolite level after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane A2 receptor(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50353645(CHEMBL1829810)
Affinity DataIC50: 198nMAssay Description:Antagonist activity at human prostanoid TP receptor expressed in QBI-HEK 293A cells assessed as inhibition of 1-BOP-induced increase in inositol mono...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane A2 receptor(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50353638(CHEMBL1829805)
Affinity DataIC50: 250nMAssay Description:Antagonist activity at human prostanoid TP receptor expressed in QBI-HEK 293A cells assessed as inhibition of 1-BOP-induced increase in inositol mono...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane A2 receptor(Mouse)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50353646(CHEMBL1829811)
Affinity DataIC50: 259nMAssay Description:Antagonist activity at mouse prostanoid TP receptor expressed in QBI-HEK 293A cells assessed as inhibition of 1-BOP-induced increase in inositol mono...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane A2 receptor(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50353636(CHEMBL1829802)
Affinity DataIC50: 377nMAssay Description:Antagonist activity at human prostanoid TP receptor expressed in QBI-HEK 293A cells assessed as inhibition of 1-BOP-induced increase in inositol mono...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane A2 receptor(Mouse)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50353644(CHEMBL1829809)
Affinity DataIC50: 463nMAssay Description:Antagonist activity at mouse prostanoid TP receptor expressed in QBI-HEK 293A cells assessed as inhibition of 1-BOP-induced increase in inositol mono...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane A2 receptor(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50353640(CHEMBL65121)
Affinity DataIC50: 523nMAssay Description:Antagonist activity against human thromboxane A2 receptor alpha expressed in QBI-HEK293A cells assessed as reduction in I-BOP-induced inositol monoph...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50009859((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...)
Affinity DataIC50: 600nMAssay Description:Inhibition of COX in RBL1 cells assessed as reduction in PGE2/D2 production using A23187-induced arachidonic acid as substrate preincubated for 2 hrs...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetThromboxane A2 receptor(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50026754(CHEMBL3335481)
Affinity DataIC50: 891nMAssay Description:Antagonist activity against human thromboxane A2 receptor alpha expressed in QBI-HEK293A cells assessed as reduction in I-BOP-induced inositol monoph...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane A2 receptor(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50026757(CHEMBL3335483)
Affinity DataIC50: 892nMAssay Description:Antagonist activity against human thromboxane A2 receptor alpha expressed in QBI-HEK293A cells assessed as reduction in I-BOP-induced inositol monoph...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50501720(CHEMBL4100090)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of COX-mediated PGD2/PGE2 production in arachidonic acid-stimulated RBL1 cells preincubated for 2 hrs followed by A23187 induction for 15 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane A2 receptor(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50058025(CHEMBL3326603)
Affinity DataIC50: 1.14E+3nMAssay Description:Inhibition of human TP receptor expressed in QBI-HEK 293A cells assessed as IP3 metabolite level after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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