Compile Data Set for Download or QSAR
Found 147 with Last Name = 'tron' and Initial = 'gc'
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Università degli Studi di Torino

Curated by ChEMBL
LigandPNGBDBM50131891(3-Methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylic a...)
Affinity DataKi:  0.0940nMAssay Description:Inhibition of [3H]-prazosin binding to cloned human Alpha-1A adrenergic receptor in CHO-cells (chinese hamster ovary cells)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Università degli Studi di Torino

Curated by ChEMBL
LigandPNGBDBM50131889(3-Methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylic a...)
Affinity DataKi:  0.160nMAssay Description:Inhibition of [3H]-prazosin binding to cloned human Alpha-1A adrenergic receptor in CHO-cells (chinese hamster ovary cells)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Universit£ degli Studi del Piemonte Orientale"A. Avogadro"

Curated by ChEMBL
LigandPNGBDBM81395(APO-866)
Affinity DataKi:  0.300nMAssay Description:Noncompetitive inhibition of NAMPT (unknown origin)More data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Università degli Studi di Torino

Curated by ChEMBL
LigandPNGBDBM50057465(3-Methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylic a...)
Affinity DataKi:  0.340nMAssay Description:Inhibition of [3H]-prazosin binding to cloned human Alpha-1A adrenergic receptor in CHO-cells (chinese hamster ovary cells)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50001775((ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methyle...)
Affinity DataKi:  0.450nMAssay Description:Binding affinity to 5HT2A receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50001775((ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methyle...)
Affinity DataKi:  0.450nMAssay Description:Binding affinity to 5HT2A receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50001775((ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methyle...)
Affinity DataKi:  0.710nMAssay Description:Binding affinity to 5HT2C receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50001775((ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methyle...)
Affinity DataKi:  0.710nMAssay Description:Binding affinity to 5HT2C receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Università degli Studi di Torino

Curated by ChEMBL
LigandPNGBDBM50131890(3-Methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylic a...)
Affinity DataKi:  0.730nMAssay Description:Inhibition of [3H]-prazosin binding to cloned human Alpha-1A adrenergic receptor in CHO-cells (chinese hamster ovary cells)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Università degli Studi di Torino

Curated by ChEMBL
LigandPNGBDBM50131891(3-Methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylic a...)
Affinity DataKi:  1.20nMAssay Description:Inhibition of [3H]-prazosin binding to cloned human Alpha-1B adrenergic receptor in CHO-cells (chinese hamster ovary cells)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Università degli Studi di Torino

Curated by ChEMBL
LigandPNGBDBM50131888(4-[2-(4-{3-[(3-Methyl-4-oxo-2-phenyl-4H-chromene-8...)
Affinity DataKi:  1.20nMAssay Description:Inhibition of [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor serotonergic receptor in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Università degli Studi di Torino

Curated by ChEMBL
LigandPNGBDBM50057465(3-Methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylic a...)
Affinity DataKi:  1.5nMAssay Description:Inhibition of [3H]-prazosin binding to cloned human Alpha-1D adrenergic receptor in CHO-cells (chinese hamster ovary cells)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Università degli Studi di Torino

Curated by ChEMBL
LigandPNGBDBM50131889(3-Methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylic a...)
Affinity DataKi:  1.60nMAssay Description:Inhibition of [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor serotonergic receptor in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Università degli Studi di Torino

Curated by ChEMBL
LigandPNGBDBM50131888(4-[2-(4-{3-[(3-Methyl-4-oxo-2-phenyl-4H-chromene-8...)
Affinity DataKi:  1.80nMAssay Description:Inhibition of [3H]-prazosin binding to cloned human Alpha-1A adrenergic receptor in CHO-cells (chinese hamster ovary cells)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Università degli Studi di Torino

Curated by ChEMBL
LigandPNGBDBM50131890(3-Methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylic a...)
Affinity DataKi:  2.20nMAssay Description:Inhibition of [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor serotonergic receptor in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Università degli Studi di Torino

Curated by ChEMBL
LigandPNGBDBM50131891(3-Methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylic a...)
Affinity DataKi:  3.5nMAssay Description:Inhibition of [3H]-prazosin binding to cloned human Alpha-1D adrenergic receptor in CHO-cells (chinese hamster ovary cells)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Università degli Studi di Torino

Curated by ChEMBL
LigandPNGBDBM50131890(3-Methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylic a...)
Affinity DataKi:  3.90nMAssay Description:Inhibition of [3H]-prazosin binding to cloned human Alpha-1D adrenergic receptor in CHO-cells (chinese hamster ovary cells)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Università degli Studi di Torino

Curated by ChEMBL
LigandPNGBDBM50057465(3-Methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylic a...)
Affinity DataKi:  3.90nMAssay Description:Inhibition of [3H]-prazosin binding to cloned human Alpha-1B adrenergic receptor in CHO-cells (chinese hamster ovary cells)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Università degli Studi di Torino

Curated by ChEMBL
LigandPNGBDBM50131889(3-Methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylic a...)
Affinity DataKi:  4.20nMAssay Description:Inhibition of [3H]-prazosin binding to cloned human Alpha-1D adrenergic receptor in CHO-cells (chinese hamster ovary cells)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Università degli Studi di Torino

Curated by ChEMBL
LigandPNGBDBM50131889(3-Methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylic a...)
Affinity DataKi:  4.70nMAssay Description:Inhibition of [3H]-prazosin binding to cloned human Alpha-1B adrenergic receptor in CHO-cells (chinese hamster ovary cells)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Università degli Studi di Torino

Curated by ChEMBL
LigandPNGBDBM50057465(3-Methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylic a...)
Affinity DataKi:  5.90nMAssay Description:Inhibition of [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor serotonergic receptor in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Università degli Studi di Torino

Curated by ChEMBL
LigandPNGBDBM50131890(3-Methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylic a...)
Affinity DataKi:  6.5nMAssay Description:Inhibition of [3H]-prazosin binding to cloned human Alpha-1B adrenergic receptor in CHO-cells (chinese hamster ovary cells)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Università degli Studi di Torino

Curated by ChEMBL
LigandPNGBDBM50131891(3-Methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylic a...)
Affinity DataKi:  7.20nMAssay Description:Inhibition of [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor serotonergic receptor in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Università degli Studi di Torino

Curated by ChEMBL
LigandPNGBDBM50131888(4-[2-(4-{3-[(3-Methyl-4-oxo-2-phenyl-4H-chromene-8...)
Affinity DataKi:  15.9nMAssay Description:Inhibition of [3H]-prazosin binding to cloned human Alpha-1B adrenergic receptor in CHO-cells (chinese hamster ovary cells)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Università degli Studi di Torino

Curated by ChEMBL
LigandPNGBDBM50131888(4-[2-(4-{3-[(3-Methyl-4-oxo-2-phenyl-4H-chromene-8...)
Affinity DataKi:  20.4nMAssay Description:Inhibition of [3H]-prazosin binding to cloned human Alpha-1D adrenergic receptor in CHO-cells (chinese hamster ovary cells)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol kinase alpha(Homo sapiens)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50529935(COCHLIOQUINONE A)
Affinity DataKi:  2.26E+3nMAssay Description:Inhibition of DGKalpha in human erythrocytes using OAG as substrate preincubated for 1 min followed by OAG addition and measured after 8 mins in pres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol kinase alpha(Homo sapiens)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50529935(COCHLIOQUINONE A)
Affinity DataKi:  2.26E+3nMAssay Description:Inhibition of DGKalpha in human erythrocytes using OAG as substrate preincubated for 1 min followed by OAG addition and measured after 8 mins in pres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol kinase alpha(Homo sapiens)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50529932(STEMPHONE)
Affinity DataKi:  3.32E+3nMAssay Description:Inhibition of DGKalpha in human erythrocytes using OAG as substrate preincubated for 1 min followed by OAG addition and measured after 8 mins in pres...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDiacylglycerol kinase alpha(Homo sapiens)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50529932(STEMPHONE)
Affinity DataKi:  3.32E+3nMAssay Description:Inhibition of DGKalpha in human erythrocytes using OAG as substrate preincubated for 1 min followed by OAG addition and measured after 8 mins in pres...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDiacylglycerol kinase alpha(Homo sapiens)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50529934(ETHYLENE GLYCOL DIOCTANOATE)
Affinity DataKi:  5.80E+4nMAssay Description:Inhibition of DGKalpha in human erythrocytes using OAG as substrate preincubated for 1 min followed by OAG addition and measured after 8 mins in pres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol kinase alpha(Homo sapiens)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50529934(ETHYLENE GLYCOL DIOCTANOATE)
Affinity DataKi:  5.80E+4nMAssay Description:Inhibition of DGKalpha in human erythrocytes using OAG as substrate preincubated for 1 min followed by OAG addition and measured after 8 mins in pres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol kinase alpha(Homo sapiens)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50529937(CHEBI:75342 | Glyceryl monooleate)
Affinity DataKi:  9.10E+4nMAssay Description:Inhibition of DGKalpha in human erythrocytes using OAG as substrate preincubated for 1 min followed by OAG addition and measured after 8 mins in pres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol kinase alpha(Homo sapiens)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50529937(CHEBI:75342 | Glyceryl monooleate)
Affinity DataKi:  9.10E+4nMAssay Description:Inhibition of DGKalpha in human erythrocytes using OAG as substrate preincubated for 1 min followed by OAG addition and measured after 8 mins in pres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Universit£ degli Studi del Piemonte Orientale"A. Avogadro"

Curated by ChEMBL
LigandPNGBDBM50439676(CHEMBL2417796)
Affinity DataIC50:  0.230nMAssay Description:Inhibition of NAMPT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Universit£ degli Studi del Piemonte Orientale"A. Avogadro"

Curated by ChEMBL
LigandPNGBDBM50347432(CHEMBL1801863)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of NAMPT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Universit£ degli Studi del Piemonte Orientale"A. Avogadro"

Curated by ChEMBL
LigandPNGBDBM50347433(CHEMBL1801864)
Affinity DataIC50:  0.450nMAssay Description:Inhibition of NAMPT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Universit£ degli Studi del Piemonte Orientale"A. Avogadro"

Curated by ChEMBL
LigandPNGBDBM50439675(CHEMBL2417788 | US11279687, Compound 196)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of NAMPT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Universit£ degli Studi del Piemonte Orientale"A. Avogadro"

Curated by ChEMBL
LigandPNGBDBM50439678(CHEMBL2417789)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of recombinant his-tagged NAMPT (unknown origin) expressed in Escherichia coli after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Mus musculus)
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM81395(APO-866)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Universit£ degli Studi del Piemonte Orientale"A. Avogadro"

Curated by ChEMBL
LigandPNGBDBM50439677(CHEMBL2417790 | US9169209, Table 3, Compound 55)
Affinity DataIC50:  3nMAssay Description:Inhibition of recombinant his-tagged NAMPT (unknown origin) expressed in Escherichia coli after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Mus musculus)
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50236217(CHEMBL4061448)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Mus musculus)
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50515548(CHEMBL4458472)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Mus musculus)
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50236220(CHEMBL4074848)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Universit£ degli Studi del Piemonte Orientale"A. Avogadro"

Curated by ChEMBL
LigandPNGBDBM50236217(CHEMBL4061448)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of NAMPT in human Jurkat T cells assessed as reduction in NAD levelsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Mus musculus)
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM81395(APO-866)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Universit£ degli Studi del Piemonte Orientale"A. Avogadro"

Curated by ChEMBL
LigandPNGBDBM50439680(CHEMBL2417798)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of recombinant his-tagged NAMPT (unknown origin) expressed in Escherichia coli after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Universit£ degli Studi del Piemonte Orientale"A. Avogadro"

Curated by ChEMBL
LigandPNGBDBM50439679(CHEMBL2417799)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of recombinant his-tagged NAMPT (unknown origin) expressed in Escherichia coli after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Universit£ degli Studi del Piemonte Orientale"A. Avogadro"

Curated by ChEMBL
LigandPNGBDBM50236220(CHEMBL4074848)
Affinity DataIC50:  6.70nMAssay Description:Inhibition of NAMPT in human Jurkat T cells assessed as reduction in NAD levelsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Universit£ degli Studi del Piemonte Orientale"A. Avogadro"

Curated by ChEMBL
LigandPNGBDBM50236219(CHEMBL4066091)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of NAMPT in human Jurkat T cells assessed as reduction in NAD levelsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Mus musculus)
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50236219(CHEMBL4066091)
Affinity DataIC50:  8.10nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 147 total ) | Next | Last >>
Jump to: