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TargetAdenosine receptor A1(Human)
Universita Di Napoli

LigandPNGBDBM21222(N-[6-methoxy-2-(methylsulfanyl)pyrimidin-4-yl]acet...)
Affinity DatapH: 7.4 T: 2°CAssay Description:The membranes prepared from CHO cells transfected with human adenosine A1 receptors were used in binding assays. Nonspecific binding was determined i...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A1(Human)
Universita Di Napoli

LigandPNGBDBM21223(N-[6-methoxy-2-(methylsulfanyl)pyrimidin-4-yl]prop...)
Affinity DatapH: 7.4 T: 2°CAssay Description:The membranes prepared from CHO cells transfected with human adenosine A1 receptors were used in binding assays. Nonspecific binding was determined i...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A1(Human)
Universita Di Napoli

LigandPNGBDBM21224(N-[2-(methylsulfanyl)-6-propoxypyrimidin-4-yl]acet...)
Affinity DatapH: 7.4 T: 2°CAssay Description:The membranes prepared from CHO cells transfected with human adenosine A1 receptors were used in binding assays. Nonspecific binding was determined i...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A1(Human)
Universita Di Napoli

LigandPNGBDBM21225(N-[2-(methylsulfanyl)-6-propoxypyrimidin-4-yl]prop...)
Affinity DatapH: 7.4 T: 2°CAssay Description:The membranes prepared from CHO cells transfected with human adenosine A1 receptors were used in binding assays. Nonspecific binding was determined i...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A1(Human)
Universita Di Napoli

LigandPNGBDBM21226(N-[6-methoxy-2-(propylsulfanyl)pyrimidin-4-yl]acet...)
Affinity DatapH: 7.4 T: 2°CAssay Description:The membranes prepared from CHO cells transfected with human adenosine A1 receptors were used in binding assays. Nonspecific binding was determined i...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A1(Human)
Universita Di Napoli

LigandPNGBDBM21230(N-[2-(benzylsulfanyl)-6-propoxypyrimidin-4-yl]acet...)
Affinity DatapH: 7.4 T: 2°CAssay Description:The membranes prepared from CHO cells transfected with human adenosine A1 receptors were used in binding assays. Nonspecific binding was determined i...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A1(Human)
Universita Di Napoli

LigandPNGBDBM21234(N-{6-[(4-chlorophenyl)methoxy]-2-(propylsulfanyl)p...)
Affinity DatapH: 7.4 T: 2°CAssay Description:The membranes prepared from CHO cells transfected with human adenosine A1 receptors were used in binding assays. Nonspecific binding was determined i...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A1(Human)
Universita Di Napoli

LigandPNGBDBM21235(N-{6-[(2,4-dichlorophenyl)methoxy]-2-(propylsulfan...)
Affinity DatapH: 7.4 T: 2°CAssay Description:The membranes prepared from CHO cells transfected with human adenosine A1 receptors were used in binding assays. Nonspecific binding was determined i...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A1(Human)
Universita Di Napoli

LigandPNGBDBM21238(N-[6-(cyclohexylmethoxy)-2-(propylsulfanyl)pyrimid...)
Affinity DatapH: 7.4 T: 2°CAssay Description:The membranes prepared from CHO cells transfected with human adenosine A1 receptors were used in binding assays. Nonspecific binding was determined i...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A1(Human)
Universita Di Napoli

LigandPNGBDBM21240(N-[2-(tert-butylsulfanyl)-6-[(4-chlorophenyl)metho...)
Affinity DatapH: 7.4 T: 2°CAssay Description:The membranes prepared from CHO cells transfected with human adenosine A1 receptors were used in binding assays. Nonspecific binding was determined i...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2a(Human)
Universita Di Napoli

LigandPNGBDBM21222(N-[6-methoxy-2-(methylsulfanyl)pyrimidin-4-yl]acet...)
Affinity DataAssay Description:The membranes prepared from CHO cells transfected with human adenosine A1 receptors were used in binding assays. Nonspecific binding was determined i...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2a(Human)
Universita Di Napoli

LigandPNGBDBM21223(N-[6-methoxy-2-(methylsulfanyl)pyrimidin-4-yl]prop...)
Affinity DataAssay Description:The membranes prepared from CHO cells transfected with human adenosine A1 receptors were used in binding assays. Nonspecific binding was determined i...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2a(Human)
Universita Di Napoli

LigandPNGBDBM21226(N-[6-methoxy-2-(propylsulfanyl)pyrimidin-4-yl]acet...)
Affinity DataAssay Description:The membranes prepared from CHO cells transfected with human adenosine A1 receptors were used in binding assays. Nonspecific binding was determined i...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2a(Human)
Universita Di Napoli

LigandPNGBDBM21227(N-[6-methoxy-2-(propylsulfanyl)pyrimidin-4-yl]prop...)
Affinity DataAssay Description:The membranes prepared from CHO cells transfected with human adenosine A1 receptors were used in binding assays. Nonspecific binding was determined i...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2a(Human)
Universita Di Napoli

LigandPNGBDBM21228(N-[6-propoxy-2-(propylsulfanyl)pyrimidin-4-yl]acet...)
Affinity DataAssay Description:The membranes prepared from CHO cells transfected with human adenosine A1 receptors were used in binding assays. Nonspecific binding was determined i...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2a(Human)
Universita Di Napoli

LigandPNGBDBM21230(N-[2-(benzylsulfanyl)-6-propoxypyrimidin-4-yl]acet...)
Affinity DataAssay Description:The membranes prepared from CHO cells transfected with human adenosine A1 receptors were used in binding assays. Nonspecific binding was determined i...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2a(Human)
Universita Di Napoli

LigandPNGBDBM21231(N-[6-(benzyloxy)-2-(propylsulfanyl)pyrimidin-4-yl]...)
Affinity DataAssay Description:The membranes prepared from CHO cells transfected with human adenosine A1 receptors were used in binding assays. Nonspecific binding was determined i...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2a(Human)
Universita Di Napoli

LigandPNGBDBM21233(N-{6-[(3-chlorophenyl)methoxy]-2-(propylsulfanyl)p...)
Affinity DataAssay Description:The membranes prepared from CHO cells transfected with human adenosine A1 receptors were used in binding assays. Nonspecific binding was determined i...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2a(Human)
Universita Di Napoli

LigandPNGBDBM21234(N-{6-[(4-chlorophenyl)methoxy]-2-(propylsulfanyl)p...)
Affinity DataAssay Description:The membranes prepared from CHO cells transfected with human adenosine A1 receptors were used in binding assays. Nonspecific binding was determined i...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2a(Human)
Universita Di Napoli

LigandPNGBDBM21235(N-{6-[(2,4-dichlorophenyl)methoxy]-2-(propylsulfan...)
Affinity DataAssay Description:The membranes prepared from CHO cells transfected with human adenosine A1 receptors were used in binding assays. Nonspecific binding was determined i...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2a(Human)
Universita Di Napoli

LigandPNGBDBM21236(N-{6-[(4-methoxyphenyl)methoxy]-2-(propylsulfanyl)...)
Affinity DataAssay Description:The membranes prepared from CHO cells transfected with human adenosine A1 receptors were used in binding assays. Nonspecific binding was determined i...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2a(Human)
Universita Di Napoli

LigandPNGBDBM21237(N-[6-(2-phenylethoxy)-2-(propylsulfanyl)pyrimidin-...)
Affinity DataAssay Description:The membranes prepared from CHO cells transfected with human adenosine A1 receptors were used in binding assays. Nonspecific binding was determined i...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2a(Human)
Universita Di Napoli

LigandPNGBDBM21238(N-[6-(cyclohexylmethoxy)-2-(propylsulfanyl)pyrimid...)
Affinity DataAssay Description:The membranes prepared from CHO cells transfected with human adenosine A1 receptors were used in binding assays. Nonspecific binding was determined i...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2a(Human)
Universita Di Napoli

LigandPNGBDBM21239(N-{6-[(4-chlorophenyl)methoxy]-2-(ethylsulfanyl)py...)
Affinity DataAssay Description:The membranes prepared from CHO cells transfected with human adenosine A1 receptors were used in binding assays. Nonspecific binding was determined i...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2a(Human)
Universita Di Napoli

LigandPNGBDBM21240(N-[2-(tert-butylsulfanyl)-6-[(4-chlorophenyl)metho...)
Affinity DataAssay Description:The membranes prepared from CHO cells transfected with human adenosine A1 receptors were used in binding assays. Nonspecific binding was determined i...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A3(Human)
Universita Di Napoli

LigandPNGBDBM21222(N-[6-methoxy-2-(methylsulfanyl)pyrimidin-4-yl]acet...)
Affinity DataAssay Description:The membranes prepared from CHO cells transfected with human adenosine A1 receptors were used in binding assays. Nonspecific binding was determined i...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A3(Human)
Universita Di Napoli

LigandPNGBDBM21223(N-[6-methoxy-2-(methylsulfanyl)pyrimidin-4-yl]prop...)
Affinity DataAssay Description:The membranes prepared from CHO cells transfected with human adenosine A1 receptors were used in binding assays. Nonspecific binding was determined i...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408220(CHEMBL4175577)
Affinity DataEC50:  69nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408224(CHEMBL4164954)
Affinity DataEC50:  1.40nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408226(CHEMBL4167303)
Affinity DataEC50:  237nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408215(CHEMBL4175177)
Affinity DataEC50:  96nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408218(CHEMBL4163771)
Affinity DataEC50:  229nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408222(CHEMBL4174442)
Affinity DataEC50:  182nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50072775(ChEMBL_75020 | 5-(1,1-Dimethyl-heptyl)-2-[(1R,2R,5...)
Affinity DataEC50:  5.5nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM21278(SR141716 | 5-(4-chlorophenyl)-1-(2,4-dichloropheny...)
Affinity DataEC50:  36nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408220(CHEMBL4175577)
Affinity DataEC50:  1.90nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408224(CHEMBL4164954)
Affinity DataEC50:  1.10nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408226(CHEMBL4167303)
Affinity DataEC50:  12nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408214(CHEMBL4163852)
Affinity DataEC50:  501nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408219(CHEMBL4165369)
Affinity DataEC50:  316nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408218(CHEMBL4163771)
Affinity DataEC50:  31nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408222(CHEMBL4174442)
Affinity DataEC50:  687nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50072775(ChEMBL_75020 | 5-(1,1-Dimethyl-heptyl)-2-[(1R,2R,5...)
Affinity DataEC50:  5.5nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50160434(AM630 | (6-iodo-2-methyl-1-(2-morpholinoethyl)-1H-...)
Affinity DataEC50:  167nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50491576(CHEMBL2381811)
Affinity DataEC50:  351nMAssay Description:Inverse agonist activity at human CB2 receptor expressed in CHO cell membrane assessed as increase in forskolin-stimulated cAMP production by scintil...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50491561(CHEMBL2381809)
Affinity DataEC50:  95nMAssay Description:Inverse agonist activity at human CB2 receptor expressed in CHO cell membrane assessed as increase in forskolin-stimulated cAMP production by scintil...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50491596(CHEMBL2381786)
Affinity DataEC50:  195nMAssay Description:Inverse agonist activity at human CB2 receptor expressed in CHO cell membrane assessed as increase in forskolin-stimulated cAMP production by scintil...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50556531(CHEMBL4779298)
Affinity DataEC50:  40nMAssay Description:Agonist activity at human CB1R expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50556532(CHEMBL4753891)
Affinity DataEC50:  56nMAssay Description:Agonist activity at human CB1R expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50556533(CHEMBL4781952)
Affinity DataEC50:  1.10nMAssay Description:Agonist activity at human CB1R expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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