Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 525 with Last Name = 'tyndall' and Initial = 'jd'
TargetCannabinoid receptor 2(Human)
University of Otago Dunedin

Curated by ChEMBL
LigandPNGBDBM50404173(CHEMBL5266788)
Affinity DataKi:  0.0750nMAssay Description:In vitro antagonism of the 5-HT-3 receptor determined by inhibition of 5-HT-induced depolarization of the isolated rat vagus nerve.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetAdenosine receptor A2a(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50094037(2-Furan-2-yl-7-[3-(4-methoxy-phenyl)-propyl]-7H-py...)
Affinity DataKi:  0.300nMAssay Description:Antagonist activity at human adenosine A2A receptor expressed in Flp-In-CHO cell membrane assessed as inhibition of NECA-induced cAMP accumulation in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50369584(CHEMBL1790230)
Affinity DataKi:  0.300nMAssay Description:Tested for inhibition of synthetic HIV-1 protease by using fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50369584(CHEMBL1790230)
Affinity DataKi:  0.300nMAssay Description:Inhibitory constant against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDimer of Gag-Pol polyprotein [491-589,Q7K,L33I,C67B,C95B](Human immunodeficiency virus type 1)
University of Queensland

LigandPNGBDBM798((2R)-2-[(7S,10S,13S)-7-amino-10-butyl-8,11-dioxo-2...)
Affinity DataKi:  0.310nM ΔG°:  -56.5kJ/molepH: 6.5 T: 37°CAssay Description:Inhibition constants were determined by a fluorometric assay. Ki values were calculated from either Dixon plots or Henderson plots in cases where the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDimer of Gag-Pol polyprotein [491-589,Q7K,L33I,C67B,C95B](Human immunodeficiency virus type 1)
University of Queensland

LigandPNGBDBM797((2S)-N-[(7S,10S,13S)-13-[(1R)-2-[(4-aminobenzene)(...)
Affinity DataKi:  0.340nM ΔG°:  -56.2kJ/molepH: 6.5 T: 37°CAssay Description:Inhibition constants were determined by a fluorometric assay. Ki values were calculated from either Dixon plots or Henderson plots in cases where the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50142990(CHEMBL288836 | N-[(R)-2-Hydroxy-2-((9S,12S)-9-isop...)
Affinity DataKi:  0.400nMAssay Description:Tested for inhibition of synthetic HIV-1 protease by using fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A1(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50581950(CHEMBL4204703)
Affinity DataKi:  0.400nMAssay Description:Antagonist activity at human adenosine A1 receptor expressed in Flp-In-CHO cell membrane assessed as inhibition of NECA-induced cAMP accumulation in ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A1(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50581955(CHEMBL5073669)
Affinity DataKi:  0.5nMAssay Description:Antagonist activity at human adenosine A1 receptor expressed in Flp-In-CHO cell membrane assessed as inhibition of forskolin-stimulated cAMP accumula...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetAdenosine receptor A1(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50581950(CHEMBL4204703)
Affinity DataKi:  0.5nMAssay Description:Antagonist activity at human adenosine A1 receptor expressed in Flp-In-CHO cell membrane assessed as inhibition of forskolin-stimulated cAMP accumula...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A1(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50581950(CHEMBL4204703)
Affinity DataKi:  0.562nMAssay Description:Displacement of [3H] DPCPX from human A1 adenosine receptor expressed in Flp-In-CHO cell membrane incubated for 4 hrs by microbeta scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A1(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50581950(CHEMBL4204703)
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H] DPCPX from human A1 adenosine receptor expressed in Flp-In-CHO cell membrane incubated for 4 hrs by microbeta scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A1(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50581964(CHEMBL5092788)
Affinity DataKi:  0.600nMAssay Description:Antagonist activity at human adenosine A1 receptor expressed in Flp-In-CHO cell membrane assessed as inhibition of forskolin-stimulated cAMP accumula...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50092152(2-Benzyl-5-(10-sec-butyl-9,12-dioxo-2-oxa-8,11-dia...)
Affinity DataKi:  0.600nMAssay Description:Inhibitory constant against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50370377(CHEMBL1790231)
Affinity DataKi:  0.600nMAssay Description:Tested for inhibition of synthetic HIV-1 protease by using fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A1(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50581957(CHEMBL5080823)
Affinity DataKi:  0.600nMAssay Description:Antagonist activity at human adenosine A1 receptor expressed in Flp-In-CHO cell membrane assessed as inhibition of forskolin-stimulated cAMP accumula...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Human)
University of Otago Dunedin

Curated by ChEMBL
LigandPNGBDBM50404172(CHEMBL5273987)
Affinity DataKi:  0.630nMAssay Description:In vitro antagonism of the 5-HT-3 receptor determined by inhibition of 5-HT-induced depolarization of the isolated rat vagus nerve.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDimer of Gag-Pol polyprotein [491-589,Q7K,L33I,C67B,C95B](Human immunodeficiency virus type 1)
University of Queensland

LigandPNGBDBM795((2R)-2-[(7S,10S,13S)-7-amino-8,11-dioxo-10-(propan...)
Affinity DataKi:  0.900nM ΔG°:  -53.7kJ/molepH: 6.5 T: 37°CAssay Description:Inhibition constants were determined by a fluorometric assay. Ki values were calculated from either Dixon plots or Henderson plots in cases where the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50142965(CHEMBL296937 | Naphthalene-2-sulfonic acid [(S)-2-...)
Affinity DataKi:  1nMAssay Description:Tested for inhibition of synthetic HIV-1 protease by using fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50142978((S)-11-{(S)-2-[Benzenesulfonyl-(3-methyl-butyl)-am...)
Affinity DataKi:  1nMAssay Description:Tested for inhibition of synthetic HIV-1 protease by using fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50370379(CHEMBL1790229)
Affinity DataKi:  1nMAssay Description:Tested for inhibition of synthetic HIV-1 protease by using fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50086884((R)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-9-oxo-1,8-di...)
Affinity DataKi:  1nMAssay Description:binding affinity towards HIV-1 Protease enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50086880(Proteolytic Enzyme inhibitor)
Affinity DataKi:  1nMAssay Description:binding affinity towards HIV-1 Protease enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2b(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50268232(8-(4-(4-(4-Chlorophenyl)piperazine-1-sulfonyl)phen...)
Affinity DataKi:  1.30nMAssay Description:Antagonist activity at human adenosine A2B receptor expressed in Flp-In-CHO cell membrane assessed as inhibition of NECA-induced cAMP accumulation in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A1(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50581960(CHEMBL5074992)
Affinity DataKi:  1.40nMAssay Description:Antagonist activity at human adenosine A1 receptor expressed in Flp-In-CHO cell membrane assessed as inhibition of forskolin-stimulated cAMP accumula...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetAdenosine receptor A1(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50581964(CHEMBL5092788)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H] DPCPX from human A1 adenosine receptor expressed in Flp-In-CHO cell membrane incubated for 4 hrs by microbeta scintillation coun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetPhenylethanolamine N-methyltransferase(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM13014(7,8-Dichloro-1,2,3,4-tetrahydro-isoquinoline; hydr...)
Affinity DataKi:  1.55nMAssay Description:Binding affinity to human wild type his-tagged PNMTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank
MMDB
PDB3D3D Structure (crystal)

TargetAdenosine receptor A1(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50581964(CHEMBL5092788)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H] DPCPX from human A1 adenosine receptor expressed in Flp-In-CHO cell membrane incubated for 4 hrs by microbeta scintillation coun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50142986(CHEMBL295464 | N-[(S)-2-(R)-Hydroxy-2-((S)-10-isop...)
Affinity DataKi:  1.60nMAssay Description:Tested for inhibition of synthetic HIV-1 protease by using fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50092151((10S,13S,1'R)-13-[1'-HYDROXY-2'-(N-P-AMINOBENZENES...)
Affinity DataKi:  1.70nMAssay Description:Tested for inhibition of synthetic HIV-1 protease by using fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB


TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50092151((10S,13S,1'R)-13-[1'-HYDROXY-2'-(N-P-AMINOBENZENES...)
Affinity DataKi:  1.70nMAssay Description:Inhibitory constant against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB


TargetDimer of Gag-Pol polyprotein [491-589,Q7K,L33I,C67B,C95B](Human immunodeficiency virus type 1)
University of Queensland

LigandPNGBDBM796(Macrocycle-containing Compound 9b | tert-butyl N-[...)
Affinity DataKi:  2nM ΔG°:  -51.6kJ/molepH: 6.5 T: 37°CAssay Description:Inhibition constants were determined by a fluorometric assay. Ki values were calculated from either Dixon plots or Henderson plots in cases where the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50142974(4-Amino-N-sec-butyl-N-[(S)-2-(R)-hydroxy-2-((S)-10...)
Affinity DataKi:  2nMAssay Description:Tested for inhibition of synthetic HIV-1 protease by using fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A1(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50581961(CHEMBL5088372)
Affinity DataKi:  2.20nMAssay Description:Antagonist activity at human adenosine A1 receptor expressed in Flp-In-CHO cell membrane assessed as inhibition of forskolin-stimulated cAMP accumula...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetAdenosine receptor A1(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50581959(CHEMBL5076192)
Affinity DataKi:  2.40nMAssay Description:Antagonist activity at human adenosine A1 receptor expressed in Flp-In-CHO cell membrane assessed as inhibition of forskolin-stimulated cAMP accumula...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetAdenosine receptor A1(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50581957(CHEMBL5080823)
Affinity DataKi:  2.80nMAssay Description:Antagonist activity at human adenosine A1 receptor expressed in Flp-In-CHO cell membrane assessed as inhibition of NECA-induced cAMP accumulation in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetDimer of Gag-Pol polyprotein [491-589,Q7K,L33I,C67B,C95B](Human immunodeficiency virus type 1)
University of Queensland

LigandPNGBDBM800(Macrocycle-containing Compound 9f | N-[(7S,10S,13S...)
Affinity DataKi:  2.80nM ΔG°:  -50.8kJ/molepH: 6.5 T: 37°CAssay Description:Inhibition constants were determined by a fluorometric assay. Ki values were calculated from either Dixon plots or Henderson plots in cases where the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A3(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50581959(CHEMBL5076192)
Affinity DataKi:  3nMAssay Description:Antagonist activity at human adenosine A3 receptor expressed in Flp-In-CHO cell membrane assessed as inhibition of NECA-induced cAMP accumulation in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50142980(4-Amino-N-cyclopentyl-N-[(S)-2-(R)-hydroxy-2-((S)-...)
Affinity DataKi:  3nMAssay Description:Tested for inhibition of synthetic HIV-1 protease by using fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDimer of Gag-Pol polyprotein [491-589,Q7K,L33I,C67B,C95B](Human immunodeficiency virus type 1)
University of Queensland

LigandPNGBDBM801((2S)-2-amino-N-[(7S,10S,13S)-13-[(1R)-2-[(4-aminob...)
Affinity DataKi:  3nM ΔG°:  -50.6kJ/molepH: 6.5 T: 37°CAssay Description:Inhibition constants were determined by a fluorometric assay. Ki values were calculated from either Dixon plots or Henderson plots in cases where the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50369797(CHEMBL1794029)
Affinity DataKi:  3nMAssay Description:binding affinity towards HIV-1 Protease enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50142966(4-Amino-N-[(S)-2-(R)-hydroxy-2-((S)-10-isopropyl-8...)
Affinity DataKi:  3nMAssay Description:Tested for inhibition of synthetic HIV-1 protease by using fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A1(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50581961(CHEMBL5088372)
Affinity DataKi:  3.30nMAssay Description:Antagonist activity at human adenosine A1 receptor expressed in Flp-In-CHO cell membrane assessed as inhibition of NECA-induced cAMP accumulation in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetAdenosine receptor A1(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50581954(CHEMBL5087305)
Affinity DataKi:  3.40nMAssay Description:Antagonist activity at human adenosine A1 receptor expressed in Flp-In-CHO cell membrane assessed as inhibition of forskolin-stimulated cAMP accumula...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetAdenosine receptor A1(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50581957(CHEMBL5080823)
Affinity DataKi:  3.5nMAssay Description:Displacement of [3H] DPCPX from human A1 adenosine receptor expressed in Flp-In-CHO cell membrane incubated for 4 hrs by microbeta scintillation coun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetAdenosine receptor A1(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50581960(CHEMBL5074992)
Affinity DataKi:  3.5nMAssay Description:Antagonist activity at human adenosine A1 receptor expressed in Flp-In-CHO cell membrane assessed as inhibition of NECA-induced cAMP accumulation in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetAdenosine receptor A1(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50581957(CHEMBL5080823)
Affinity DataKi:  3.5nMAssay Description:Displacement of [3H] DPCPX from human A1 adenosine receptor expressed in Flp-In-CHO cell membrane incubated for 4 hrs by microbeta scintillation coun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetAdenosine receptor A1(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50581959(CHEMBL5076192)
Affinity DataKi:  3.70nMAssay Description:Displacement of [3H] DPCPX from human A1 adenosine receptor expressed in Flp-In-CHO cell membrane incubated for 4 hrs by microbeta scintillation coun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetAdenosine receptor A1(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50581959(CHEMBL5076192)
Affinity DataKi:  3.70nMAssay Description:Displacement of [3H] DPCPX from human A1 adenosine receptor expressed in Flp-In-CHO cell membrane incubated for 4 hrs by microbeta scintillation coun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetAdenosine receptor A1(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50581958(CHEMBL5089483)
Affinity DataKi:  3.90nMAssay Description:Antagonist activity at human adenosine A1 receptor expressed in Flp-In-CHO cell membrane assessed as inhibition of NECA-induced cAMP accumulation in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

Displayed 1 to 50 (of 525 total ) | Next | Last >>
Jump to: