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TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50102692(ORG-25543 | 4-Benzyloxy-N-(1-dimethylamino-cyclope...)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50102692(ORG-25543 | 4-Benzyloxy-N-(1-dimethylamino-cyclope...)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human GlyT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50537022(CHEMBL4587165)
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50537040(CHEMBL4515597)
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50537034(CHEMBL4572247)
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50537044(CHEMBL4562565)
Affinity DataIC50: 48nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50537033(CHEMBL4535356)
Affinity DataIC50: 48nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50537043(CHEMBL4227139)
Affinity DataIC50: 55nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50537049(CHEMBL4527071)
Affinity DataIC50: 65nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50537023(CHEMBL4542099)
Affinity DataIC50: 69nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50537054(CHEMBL4549008)
Affinity DataIC50: 91nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50256745((2S)-2-amino-3-((2-(benzyloxy)phenyl)(3-fluorophen...)
Affinity DataIC50: 100nMAssay Description:Inhibition of full length human GlyT2 expressed in FreeStyle 293-F suspension cells incubated for 30 mins before [3H]glycine addition and measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50023924(CHEMBL3325507)
Affinity DataIC50: 105nMAssay Description:Reversible inhibition of recombinant human GlyT2 expressed in HEK293 cells assessed as reduction in [3H]-glycine uptake after 2 hrs by top count assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50537031(CHEMBL4540633)
Affinity DataIC50: 130nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50537017(CHEMBL4228560)
Affinity DataIC50: 143nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50537029(CHEMBL4592570)
Affinity DataIC50: 151nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50537045(CHEMBL4562110)
Affinity DataIC50: 152nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50537035(CHEMBL4549529)
Affinity DataIC50: 182nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50537028(CHEMBL4228763)
Affinity DataIC50: 214nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50537048(CHEMBL4576431)
Affinity DataIC50: 259nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50537019(CHEMBL4526987)
Affinity DataIC50: 259nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50537032(CHEMBL4559571)
Affinity DataIC50: 313nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50537046(CHEMBL4531406)
Affinity DataIC50: 340nMAssay Description:Reversible non-competitive inhibition of human GlyT2a expressed in Xenopus laevis oocytes by two-electrode voltage clamp electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50537041(CHEMBL4515758)
Affinity DataIC50: 496nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50537018(CHEBI:73723 | Oleoyl Glycine)
Affinity DataIC50: 500nMAssay Description:Reversible non-competitive inhibition of human GlyT2a expressed in Xenopus laevis oocytes by two-electrode voltage clamp electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50537018(CHEBI:73723 | Oleoyl Glycine)
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50537036(CHEMBL4559157)
Affinity DataIC50: 560nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50537024(CHEMBL3392050 | CHEBI:17490)
Affinity DataIC50: 600nMAssay Description:Reversible non-competitive inhibition of human GlyT2a expressed in Xenopus laevis oocytes by two-electrode voltage clamp electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50537042(CHEMBL4526841)
Affinity DataIC50: 613nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50537025(CHEMBL4545242)
Affinity DataIC50: 865nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50537047(CHEMBL4543598)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50537038(CHEMBL4516669)
Affinity DataIC50: 1.17E+3nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50537051(CHEMBL226397 | Oleoyl L-Alanine)
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50537050(CHEMBL4576550)
Affinity DataIC50: 1.81E+3nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50537037(CHEMBL4578795)
Affinity DataIC50: 2.33E+3nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50537041(CHEMBL4515758)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of recombinant human GlyT1b expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50537048(CHEMBL4576431)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of recombinant human GlyT1b expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50537049(CHEMBL4527071)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of recombinant human GlyT1b expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50537044(CHEMBL4562565)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of recombinant human GlyT1b expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50537045(CHEMBL4562110)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of recombinant human GlyT1b expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50537054(CHEMBL4549008)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of recombinant human GlyT1b expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50537040(CHEMBL4515597)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of recombinant human GlyT1b expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50537035(CHEMBL4549529)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of recombinant human GlyT1b expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50537034(CHEMBL4572247)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of recombinant human GlyT1b expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50537033(CHEMBL4535356)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of recombinant human GlyT1b expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50537023(CHEMBL4542099)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of recombinant human GlyT1b expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50537032(CHEMBL4559571)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of recombinant human GlyT1b expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50537031(CHEMBL4540633)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of recombinant human GlyT1b expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50537022(CHEMBL4587165)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of recombinant human GlyT1b expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50537036(CHEMBL4559157)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of recombinant human GlyT1b expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
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