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TargetSon of sevenless homolog 1(Human)
Schrödinger, Inc.

US Patent
LigandPNGBDBM692013(US20240279221, Example 2)
Affinity DataKd:  57nMAssay Description:Binding to SOS1 was measured using a SPR assay with purified recombinant human SOS1 substrate (res. 564-1049 with N-terminal Avi tag; purified and bi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSon of sevenless homolog 1(Human)
Schrödinger, Inc.

US Patent
LigandPNGBDBM692014(US20240279221, Example 3)
Affinity DataKd:  63nMAssay Description:Binding to SOS1 was measured using a SPR assay with purified recombinant human SOS1 substrate (res. 564-1049 with N-terminal Avi tag; purified and bi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSon of sevenless homolog 1(Human)
Schrödinger, Inc.

US Patent
LigandPNGBDBM692015(US20240279221, Example 4)
Affinity DataKd:  22nMAssay Description:Binding to SOS1 was measured using a SPR assay with purified recombinant human SOS1 substrate (res. 564-1049 with N-terminal Avi tag; purified and bi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSon of sevenless homolog 1(Human)
Schrödinger, Inc.

US Patent
LigandPNGBDBM692016(US20240279221, Example 5)
Affinity DataKd:  22nMAssay Description:Binding to SOS1 was measured using a SPR assay with purified recombinant human SOS1 substrate (res. 564-1049 with N-terminal Avi tag; purified and bi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSon of sevenless homolog 1(Human)
Schrödinger, Inc.

US Patent
LigandPNGBDBM692017(US20240279221, Example 6)
Affinity DataKd:  44nMAssay Description:Binding to SOS1 was measured using a SPR assay with purified recombinant human SOS1 substrate (res. 564-1049 with N-terminal Avi tag; purified and bi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSon of sevenless homolog 1(Human)
Schrödinger, Inc.

US Patent
LigandPNGBDBM692018(US20240279221, Example 7)
Affinity DataKd:  259nMAssay Description:Binding to SOS1 was measured using a SPR assay with purified recombinant human SOS1 substrate (res. 564-1049 with N-terminal Avi tag; purified and bi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSon of sevenless homolog 1(Human)
Schrödinger, Inc.

US Patent
LigandPNGBDBM692020(US20240279221, Example 9)
Affinity DataKd:  64nMAssay Description:Binding to SOS1 was measured using a SPR assay with purified recombinant human SOS1 substrate (res. 564-1049 with N-terminal Avi tag; purified and bi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSon of sevenless homolog 1(Human)
Schrödinger, Inc.

US Patent
LigandPNGBDBM692021(US20240279221, Example 10)
Affinity DataKd:  136nMAssay Description:Binding to SOS1 was measured using a SPR assay with purified recombinant human SOS1 substrate (res. 564-1049 with N-terminal Avi tag; purified and bi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSon of sevenless homolog 1(Human)
Schrödinger, Inc.

US Patent
LigandPNGBDBM692022(US20240279221, Example 11)
Affinity DataKd:  95nMAssay Description:Binding to SOS1 was measured using a SPR assay with purified recombinant human SOS1 substrate (res. 564-1049 with N-terminal Avi tag; purified and bi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSon of sevenless homolog 1(Human)
Schrödinger, Inc.

US Patent
LigandPNGBDBM692023(US20240279221, Example 12)
Affinity DataKd:  290nMAssay Description:Binding to SOS1 was measured using a SPR assay with purified recombinant human SOS1 substrate (res. 564-1049 with N-terminal Avi tag; purified and bi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSon of sevenless homolog 1(Human)
Schrödinger, Inc.

US Patent
LigandPNGBDBM692024(US20240279221, Example 13)
Affinity DataKd:  25nMAssay Description:Binding to SOS1 was measured using a SPR assay with purified recombinant human SOS1 substrate (res. 564-1049 with N-terminal Avi tag; purified and bi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSon of sevenless homolog 1(Human)
Schrödinger, Inc.

US Patent
LigandPNGBDBM692025(US20240279221, Example 14)
Affinity DataKd:  87nMAssay Description:Binding to SOS1 was measured using a SPR assay with purified recombinant human SOS1 substrate (res. 564-1049 with N-terminal Avi tag; purified and bi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSon of sevenless homolog 1(Human)
Schrödinger, Inc.

US Patent
LigandPNGBDBM692026(US20240279221, Example 15)
Affinity DataKd:  40nMAssay Description:Binding to SOS1 was measured using a SPR assay with purified recombinant human SOS1 substrate (res. 564-1049 with N-terminal Avi tag; purified and bi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSon of sevenless homolog 1(Human)
Schrödinger, Inc.

US Patent
LigandPNGBDBM692027(US20240279221, Example 16)
Affinity DataKd:  84nMAssay Description:Binding to SOS1 was measured using a SPR assay with purified recombinant human SOS1 substrate (res. 564-1049 with N-terminal Avi tag; purified and bi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSon of sevenless homolog 1(Human)
Schrödinger, Inc.

US Patent
LigandPNGBDBM692028(US20240279221, Example 17)
Affinity DataKd:  31nMAssay Description:Binding to SOS1 was measured using a SPR assay with purified recombinant human SOS1 substrate (res. 564-1049 with N-terminal Avi tag; purified and bi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSon of sevenless homolog 1(Human)
Schrödinger, Inc.

US Patent
LigandPNGBDBM692029(US20240279221, Example 18)
Affinity DataKd:  16nMAssay Description:Binding to SOS1 was measured using a SPR assay with purified recombinant human SOS1 substrate (res. 564-1049 with N-terminal Avi tag; purified and bi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSon of sevenless homolog 1(Human)
Schrödinger, Inc.

US Patent
LigandPNGBDBM692030(US20240279221, Example 19)
Affinity DataKd:  161nMAssay Description:Binding to SOS1 was measured using a SPR assay with purified recombinant human SOS1 substrate (res. 564-1049 with N-terminal Avi tag; purified and bi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSon of sevenless homolog 1(Human)
Schrödinger, Inc.

US Patent
LigandPNGBDBM692031(US20240279221, Example 20)
Affinity DataKd:  63nMAssay Description:Binding to SOS1 was measured using a SPR assay with purified recombinant human SOS1 substrate (res. 564-1049 with N-terminal Avi tag; purified and bi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSon of sevenless homolog 1(Human)
Schrödinger, Inc.

US Patent
LigandPNGBDBM692032(US20240279221, Example 21)
Affinity DataKd:  70nMAssay Description:Binding to SOS1 was measured using a SPR assay with purified recombinant human SOS1 substrate (res. 564-1049 with N-terminal Avi tag; purified and bi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSon of sevenless homolog 1(Human)
Schrödinger, Inc.

US Patent
LigandPNGBDBM692033(US20240279221, Example 22)
Affinity DataKd:  74nMAssay Description:Binding to SOS1 was measured using a SPR assay with purified recombinant human SOS1 substrate (res. 564-1049 with N-terminal Avi tag; purified and bi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSon of sevenless homolog 1(Human)
Schrödinger, Inc.

US Patent
LigandPNGBDBM692035(US20240279221, Example 24)
Affinity DataKd:  34nMAssay Description:Binding to SOS1 was measured using a SPR assay with purified recombinant human SOS1 substrate (res. 564-1049 with N-terminal Avi tag; purified and bi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSon of sevenless homolog 1(Human)
Schrödinger, Inc.

US Patent
LigandPNGBDBM692036(US20240279221, Example 25 | US20240279221, Example...)
Affinity DataKd:  225nMAssay Description:Binding to SOS1 was measured using a SPR assay with purified recombinant human SOS1 substrate (res. 564-1049 with N-terminal Avi tag; purified and bi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSon of sevenless homolog 1(Human)
Schrödinger, Inc.

US Patent
LigandPNGBDBM692036(US20240279221, Example 25 | US20240279221, Example...)
Affinity DataKd: >5.00E+4nMAssay Description:Binding to SOS1 was measured using a SPR assay with purified recombinant human SOS1 substrate (res. 564-1049 with N-terminal Avi tag; purified and bi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSon of sevenless homolog 1(Human)
Schrödinger, Inc.

US Patent
LigandPNGBDBM692038(US20240279221, Example 28 | (R)-6-(1-((6-cycloprop...)
Affinity DataKd:  134nMAssay Description:Binding to SOS1 was measured using a SPR assay with purified recombinant human SOS1 substrate (res. 564-1049 with N-terminal Avi tag; purified and bi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSon of sevenless homolog 1(Human)
Schrödinger, Inc.

US Patent
LigandPNGBDBM692038(US20240279221, Example 28 | (R)-6-(1-((6-cycloprop...)
Affinity DataKd:  3.02E+3nMAssay Description:Binding to SOS1 was measured using a SPR assay with purified recombinant human SOS1 substrate (res. 564-1049 with N-terminal Avi tag; purified and bi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSon of sevenless homolog 1(Human)
Schrödinger, Inc.

US Patent
LigandPNGBDBM692040(US20240279221, Example 29)
Affinity DataKd:  42nMAssay Description:Binding to SOS1 was measured using a SPR assay with purified recombinant human SOS1 substrate (res. 564-1049 with N-terminal Avi tag; purified and bi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSon of sevenless homolog 1(Human)
Schrödinger, Inc.

US Patent
LigandPNGBDBM692041(US20240279221, Example 30 | 4-(((R)-1-(3-(difluoro...)
Affinity DataKd:  9nMAssay Description:Binding to SOS1 was measured using a SPR assay with purified recombinant human SOS1 substrate (res. 564-1049 with N-terminal Avi tag; purified and bi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSon of sevenless homolog 1(Human)
Schrödinger, Inc.

US Patent
LigandPNGBDBM692041(US20240279221, Example 30 | 4-(((R)-1-(3-(difluoro...)
Affinity DataKd:  45nMAssay Description:Binding to SOS1 was measured using a SPR assay with purified recombinant human SOS1 substrate (res. 564-1049 with N-terminal Avi tag; purified and bi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSon of sevenless homolog 1(Human)
Schrödinger, Inc.

US Patent
LigandPNGBDBM692043(US20240279221, Example 32 | 4-(((R)-1-(3-(difluoro...)
Affinity DataKd:  229nMAssay Description:Binding to SOS1 was measured using a SPR assay with purified recombinant human SOS1 substrate (res. 564-1049 with N-terminal Avi tag; purified and bi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSon of sevenless homolog 1(Human)
Schrödinger, Inc.

US Patent
LigandPNGBDBM692043(US20240279221, Example 32 | 4-(((R)-1-(3-(difluoro...)
Affinity DataKd:  8nMAssay Description:Binding to SOS1 was measured using a SPR assay with purified recombinant human SOS1 substrate (res. 564-1049 with N-terminal Avi tag; purified and bi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSon of sevenless homolog 1(Human)
Schrödinger, Inc.

US Patent
LigandPNGBDBM692045(US20240279221, Example 34 | US20240279221, Example...)
Affinity DataKd:  10nMAssay Description:Binding to SOS1 was measured using a SPR assay with purified recombinant human SOS1 substrate (res. 564-1049 with N-terminal Avi tag; purified and bi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSon of sevenless homolog 1(Human)
Schrödinger, Inc.

US Patent
LigandPNGBDBM692045(US20240279221, Example 34 | US20240279221, Example...)
Affinity DataKd:  17nMAssay Description:Binding to SOS1 was measured using a SPR assay with purified recombinant human SOS1 substrate (res. 564-1049 with N-terminal Avi tag; purified and bi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSon of sevenless homolog 1(Human)
Schrödinger, Inc.

US Patent
LigandPNGBDBM692047(US20240279221, Example 36)
Affinity DataKd:  16nMAssay Description:Binding to SOS1 was measured using a SPR assay with purified recombinant human SOS1 substrate (res. 564-1049 with N-terminal Avi tag; purified and bi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSon of sevenless homolog 1(Human)
Schrödinger, Inc.

US Patent
LigandPNGBDBM692049(US20240279221, Example 38 | US20240279221, Example...)
Affinity DataKd:  43nMAssay Description:Binding to SOS1 was measured using a SPR assay with purified recombinant human SOS1 substrate (res. 564-1049 with N-terminal Avi tag; purified and bi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSon of sevenless homolog 1(Human)
Schrödinger, Inc.

US Patent
LigandPNGBDBM692049(US20240279221, Example 38 | US20240279221, Example...)
Affinity DataKd:  43nMAssay Description:Binding to SOS1 was measured using a SPR assay with purified recombinant human SOS1 substrate (res. 564-1049 with N-terminal Avi tag; purified and bi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSon of sevenless homolog 1(Human)
Schrödinger, Inc.

US Patent
LigandPNGBDBM692051(US20240279221, Example 40)
Affinity DataKd:  9nMAssay Description:Binding to SOS1 was measured using a SPR assay with purified recombinant human SOS1 substrate (res. 564-1049 with N-terminal Avi tag; purified and bi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSon of sevenless homolog 1(Human)
Schrödinger, Inc.

US Patent
LigandPNGBDBM692052(US20240279221, Example 41)
Affinity DataKd:  14nMAssay Description:Binding to SOS1 was measured using a SPR assay with purified recombinant human SOS1 substrate (res. 564-1049 with N-terminal Avi tag; purified and bi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSon of sevenless homolog 1(Human)
Schrödinger, Inc.

US Patent
LigandPNGBDBM692053(US20240279221, Example 42)
Affinity DataKd:  34nMAssay Description:Binding to SOS1 was measured using a SPR assay with purified recombinant human SOS1 substrate (res. 564-1049 with N-terminal Avi tag; purified and bi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSon of sevenless homolog 1(Human)
Schrödinger, Inc.

US Patent
LigandPNGBDBM692054(US20240279221, Example 43)
Affinity DataKd:  24nMAssay Description:Binding to SOS1 was measured using a SPR assay with purified recombinant human SOS1 substrate (res. 564-1049 with N-terminal Avi tag; purified and bi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSon of sevenless homolog 1(Human)
Schrödinger, Inc.

US Patent
LigandPNGBDBM692056(US20240279221, Example 44 | US20240279221, Example...)
Affinity DataKd: >5.00E+3nMAssay Description:Binding to SOS1 was measured using a SPR assay with purified recombinant human SOS1 substrate (res. 564-1049 with N-terminal Avi tag; purified and bi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSon of sevenless homolog 1(Human)
Schrödinger, Inc.

US Patent
LigandPNGBDBM692056(US20240279221, Example 44 | US20240279221, Example...)
Affinity DataKd:  10nMAssay Description:Binding to SOS1 was measured using a SPR assay with purified recombinant human SOS1 substrate (res. 564-1049 with N-terminal Avi tag; purified and bi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSon of sevenless homolog 1(Human)
Schrödinger, Inc.

US Patent
LigandPNGBDBM692058(US20240279221, Example 46)
Affinity DataKd:  21nMAssay Description:Binding to SOS1 was measured using a SPR assay with purified recombinant human SOS1 substrate (res. 564-1049 with N-terminal Avi tag; purified and bi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSon of sevenless homolog 1(Human)
Schrödinger, Inc.

US Patent
LigandPNGBDBM692059(US20240279221, Example 47)
Affinity DataKd:  6nMAssay Description:Binding to SOS1 was measured using a SPR assay with purified recombinant human SOS1 substrate (res. 564-1049 with N-terminal Avi tag; purified and bi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSon of sevenless homolog 1(Human)
Schrödinger, Inc.

US Patent
LigandPNGBDBM692060(US20240279221, Example 48)
Affinity DataKd:  75nMAssay Description:Binding to SOS1 was measured using a SPR assay with purified recombinant human SOS1 substrate (res. 564-1049 with N-terminal Avi tag; purified and bi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSon of sevenless homolog 1(Human)
Schrödinger, Inc.

US Patent
LigandPNGBDBM692061(US20240279221, Example 49)
Affinity DataKd:  13nMAssay Description:Binding to SOS1 was measured using a SPR assay with purified recombinant human SOS1 substrate (res. 564-1049 with N-terminal Avi tag; purified and bi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSon of sevenless homolog 1(Human)
Schrödinger, Inc.

US Patent
LigandPNGBDBM692062(US20240279221, Example 50)
Affinity DataKd:  29nMAssay Description:Binding to SOS1 was measured using a SPR assay with purified recombinant human SOS1 substrate (res. 564-1049 with N-terminal Avi tag; purified and bi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSon of sevenless homolog 1(Human)
Schrödinger, Inc.

US Patent
LigandPNGBDBM692063(US20240279221, Example 51)
Affinity DataKd:  17nMAssay Description:Binding to SOS1 was measured using a SPR assay with purified recombinant human SOS1 substrate (res. 564-1049 with N-terminal Avi tag; purified and bi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSon of sevenless homolog 1(Human)
Schrödinger, Inc.

US Patent
LigandPNGBDBM692064(US20240279221, Example 52 | 4-(((R)-1-(3-(difluoro...)
Affinity DataKd:  76nMAssay Description:Binding to SOS1 was measured using a SPR assay with purified recombinant human SOS1 substrate (res. 564-1049 with N-terminal Avi tag; purified and bi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSon of sevenless homolog 1(Human)
Schrödinger, Inc.

US Patent
LigandPNGBDBM692064(US20240279221, Example 52 | 4-(((R)-1-(3-(difluoro...)
Affinity DataKd:  7nMAssay Description:Binding to SOS1 was measured using a SPR assay with purified recombinant human SOS1 substrate (res. 564-1049 with N-terminal Avi tag; purified and bi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSon of sevenless homolog 1(Human)
Schrödinger, Inc.

US Patent
LigandPNGBDBM692066(US20240279221, Example 54 | 2-methyl-4-(((R)-1-(2-...)
Affinity DataKd:  125nMAssay Description:Binding to SOS1 was measured using a SPR assay with purified recombinant human SOS1 substrate (res. 564-1049 with N-terminal Avi tag; purified and bi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

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