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TargetIntegrin alpha-V/beta-3(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50464108(CHEMBL4241824)
Affinity DataKd:  18nMAssay Description:Binding affinity to human integrin alphaVbeta3 by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50464108(CHEMBL4241824)
Affinity DataEC50:  0.158nMAssay Description:Induction of integrin alphaVbeta6 receptor internalization in human primary human lung epithelial cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50464108(CHEMBL4241824)
Affinity DataKd:  21nMAssay Description:Binding affinity to human integrin alphaVbeta5 by after 2 hrs liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50464108(CHEMBL4241824)
Affinity DataKd:  0.0160nMAssay Description:Binding affinity to human integrin alphaVbeta6 after 24 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-5/beta-1(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50464108(CHEMBL4241824)
Affinity DataKd:  100nMAssay Description:Binding affinity to human integrin alpha5beta1 after 6 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-1(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50464108(CHEMBL4241824)
Affinity DataKd:  2.60nMAssay Description:Binding affinity to human integrin alphaVbeta1 after 6 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-8(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50464108(CHEMBL4241824)
Affinity DataKd:  2.80nMAssay Description:Binding affinity to human integrin alphaVbeta8 after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-5/beta-1(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50464108(CHEMBL4241824)
Affinity DataKd:  0.257nMAssay Description:Binding affinity to human integrin alpha8beta1 by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-1(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50464108(CHEMBL4241824)
Affinity DataKd:  2.60nMAssay Description:Binding affinity to human integrin alphaVbeta1 after 6 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50464108(CHEMBL4241824)
Affinity DataKd:  21nMAssay Description:Binding affinity to human integrin alphaVbeta5 by after 2 hrs liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-8(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50464108(CHEMBL4241824)
Affinity DataKd:  2.70nMAssay Description:Binding affinity to human integrin alphaVbeta8 after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-5/beta-1(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50464108(CHEMBL4241824)
Affinity DataKd:  0.260nMAssay Description:Binding affinity to human integrin alpha8beta1 by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-5/beta-1(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50464108(CHEMBL4241824)
Affinity DataKd:  100nMAssay Description:Binding affinity to human integrin alpha5beta1 after 6 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50464108(CHEMBL4241824)
Affinity DataKd:  0.0158nMAssay Description:Binding affinity to human integrin alphaVbeta6 after 24 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50464108(CHEMBL4241824)
Affinity DataKd:  18nMAssay Description:Binding affinity to human integrin alphaVbeta3 by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50513974(CHEMBL4513624)
Affinity DataIC50: 0.794nMAssay Description:Inhibition of recombinant human integrin alphaV (31 to 992 residues) beta3 (27 to 718 residues) expressed in CHO cells preincubated for 15 mins follo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50497716(CHEMBL3319237)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of integrin alphavbeta3 (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50464108(CHEMBL4241824)
Affinity DataIC50: 1nMAssay Description:Antagonist activity at human integrin alphaVbeta6 in lung tissue slices derived from IPF patient assessed as reduction in SMAD2 phosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50464106(CHEMBL4237498)
Affinity DataIC50: 1nMAssay Description:Antagonist activity at human integrin alphaVbeta6 expressed in human K562 cells assessed as reduction in cell adhesion to GST-LAP after 30 mins by BC...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-8(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50497714(Glpg-0187 | Glpg0187)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of ligand binding to integrin alphavbeta8 (unknown origin) expressed in baculovirus expression system after 2 hrs by solid-phase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50513966(CHEMBL4468875)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of recombinant human integrin alphaV (31 to 992 residues) beta3 (27 to 718 residues) expressed in CHO cells preincubated for 15 mins follo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-1(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50497714(Glpg-0187 | Glpg0187)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of ligand binding to integrin alphavbeta1 (unknown origin) expressed in baculovirus expression system after 2 hrs by solid-phase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50497714(Glpg-0187 | Glpg0187)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of ligand binding to integrin alphavbeta6 (unknown origin) expressed in baculovirus expression system after 2 hrs by solid-phase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50497716(CHEMBL3319237)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of integrin alphavbeta6 (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50464105(CHEMBL4246111)
Affinity DataIC50: 1.60nMAssay Description:Antagonist activity at human integrin alphaVbeta6 expressed in human K562 cells assessed as reduction in cell adhesion to GST-LAP after 30 mins by BC...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50464118(CHEMBL4249172)
Affinity DataIC50: 1.60nMAssay Description:Antagonist activity at human integrin alphaVbeta6 expressed in human K562 cells assessed as reduction in cell adhesion to GST-LAP after 30 mins by BC...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50464099(CHEMBL4243686)
Affinity DataIC50: 1.60nMAssay Description:Antagonist activity at human integrin alphaVbeta6 expressed in human K562 cells assessed as reduction in cell adhesion to GST-LAP after 30 mins by BC...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50464100(CHEMBL4243367)
Affinity DataIC50: 1.60nMAssay Description:Antagonist activity at human integrin alphaVbeta6 expressed in human K562 cells assessed as reduction in cell adhesion to GST-LAP after 30 mins by BC...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-1(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50497716(CHEMBL3319237)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human fibronectin binding to human integrin alphavbeta1 after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50464104(CHEMBL4244784)
Affinity DataIC50: 2nMAssay Description:Antagonist activity at human integrin alphaVbeta6 expressed in human K562 cells assessed as reduction in cell adhesion to GST-LAP after 30 mins by BC...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50464103(CHEMBL4245368)
Affinity DataIC50: 2nMAssay Description:Antagonist activity at human integrin alphaVbeta6 expressed in human K562 cells assessed as reduction in cell adhesion to GST-LAP after 30 mins by BC...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50464104(CHEMBL4244784)
Affinity DataIC50: 2nMAssay Description:Antagonist activity at human integrin alphaVbeta6 expressed in human K562 cells assessed as reduction in cell adhesion to GST-LAP after 30 mins by BC...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50513970(CHEMBL4557585)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human integrin alphaV (31 to 992 residues) beta3 (27 to 718 residues) expressed in CHO cells preincubated for 15 mins follo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50513980(CHEMBL4451803)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human integrin alphaV (31 to 992 residues) beta3 (27 to 718 residues) expressed in CHO cells preincubated for 15 mins follo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50513988(CHEMBL4445933)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human integrin alphaV (31 to 992 residues) beta3 (27 to 718 residues) expressed in CHO cells preincubated for 15 mins follo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50513976(CHEMBL4539942)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human integrin alphaV (31 to 992 residues) beta3 (27 to 718 residues) expressed in CHO cells preincubated for 15 mins follo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50464100(CHEMBL4243367)
Affinity DataIC50: 2nMAssay Description:Inhibition of integrin alphavbeta6 (unknown origin) expressed in human K562 cells assessed as reduction in cell adhesion to GST-LAP1 (242 to 252 amin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50497714(Glpg-0187 | Glpg0187)
Affinity DataIC50: 2nMAssay Description:Inhibition of ligand binding to integrin alphavbeta5 (unknown origin) expressed in baculovirus expression system after 2 hrs by solid-phase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50464102(CHEMBL4251444)
Affinity DataIC50: 2.5nMAssay Description:Antagonist activity at human integrin alphaVbeta6 expressed in human K562 cells assessed as reduction in cell adhesion to GST-LAP after 30 mins by BC...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50464113(CHEMBL4239085)
Affinity DataIC50: 2.5nMAssay Description:Antagonist activity at human integrin alphaVbeta6 expressed in human K562 cells assessed as reduction in cell adhesion to GST-LAP after 30 mins by BC...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50464101(CHEMBL4242732)
Affinity DataIC50: 2.5nMAssay Description:Antagonist activity at human integrin alphaVbeta6 expressed in human K562 cells assessed as reduction in cell adhesion to GST-LAP after 30 mins by BC...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50464124(CHEMBL4249629)
Affinity DataIC50: 2.5nMAssay Description:Antagonist activity at human integrin alphaVbeta6 expressed in human K562 cells assessed as reduction in cell adhesion to GST-LAP after 30 mins by BC...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50464107(CHEMBL4240155)
Affinity DataIC50: 2.5nMAssay Description:Antagonist activity at human integrin alphaVbeta6 expressed in human K562 cells assessed as reduction in cell adhesion to GST-LAP after 30 mins by BC...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-8(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50464106(CHEMBL4237498)
Affinity DataIC50: 2.5nMAssay Description:Antagonist activity at human integrin alphaVbeta8 expressed in human K562 cells assessed as reduction in cell adhesion to GST-LAP after 30 mins by BC...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50513973(CHEMBL4458205)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of recombinant human integrin alphaV (31 to 992 residues) beta3 (27 to 718 residues) expressed in CHO cells preincubated for 15 mins follo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50464113(CHEMBL4239085)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of integrin alphavbeta6 (unknown origin) expressed in human K562 cells assessed as reduction in cell adhesion to GST-LAP1 (242 to 252 amin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50464116(CHEMBL4242175)
Affinity DataIC50: 3.20nMAssay Description:Antagonist activity at human integrin alphaVbeta5 expressed in human K562 cells assessed as reduction in cell adhesion to vitronectin after 30 mins b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-8(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50464116(CHEMBL4242175)
Affinity DataIC50: 3.20nMAssay Description:Antagonist activity at human integrin alphaVbeta8 expressed in human K562 cells assessed as reduction in cell adhesion to GST-LAP after 30 mins by BC...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50464119(CHEMBL4241584)
Affinity DataIC50: 3.20nMAssay Description:Antagonist activity at human integrin alphaVbeta6 expressed in human K562 cells assessed as reduction in cell adhesion to GST-LAP after 30 mins by BC...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50513977(CHEMBL4588580)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of recombinant human integrin alphaV (31 to 992 residues) beta3 (27 to 718 residues) expressed in CHO cells preincubated for 15 mins follo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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