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TargetAdenosine receptor A3(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50205710((2S,3S,4R)-3,4-dihydroxy-5-((R)-6-methoxyamino-2-p...)
Affinity DataEC50:  120nMAssay Description:Agonist activity at human recombinant adenosine A3 receptor expressed in CHO cells assessed as nonradiaoactive DELFIA Eu-GTP binding treated for 15 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50299700((2S,3S,4R,5R)-3,4-dihydroxy-5-(6-(methoxyamino)-2-...)
Affinity DataEC50:  112nMAssay Description:Agonist activity at human recombinant adenosine A3 receptor expressed in CHO cells assessed as nonradiaoactive DELFIA Eu-GTP binding treated for 15 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50205722(2-[(4-fluorophenyl)ethynyl]-N6-methoxy-5'-N-methyl...)
Affinity DataEC50:  210nMAssay Description:Agonist activity at human recombinant adenosine A3 receptor expressed in CHO cells assessed as nonradiaoactive DELFIA Eu-GTP binding treated for 15 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50205729((2S,3S,4R,5R)-3,4-dihydroxy-5-(6-(methoxyamino)-2-...)
Affinity DataEC50:  52nMAssay Description:Agonist activity at human recombinant adenosine A3 receptor expressed in CHO cells assessed as nonradiaoactive DELFIA Eu-GTP binding treated for 15 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50299701(N6-Methyl-2-phenylethynyl-5'-N-methylcarboxamidoad...)
Affinity DataEC50:  151nMAssay Description:Agonist activity at human recombinant adenosine A3 receptor expressed in CHO cells assessed as nonradiaoactive DELFIA Eu-GTP binding treated for 15 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50299702(2-(4-Acetylphenyl)ethynyl-N6-methyl-5'-N-methylcar...)
Affinity DataEC50:  240nMAssay Description:Agonist activity at human recombinant adenosine A3 receptor expressed in CHO cells assessed as nonradiaoactive DELFIA Eu-GTP binding treated for 15 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50299703(2-(4-Fluorophenyl)ethynyl-N6-methyl-5'-N-methylcar...)
Affinity DataEC50:  190nMAssay Description:Agonist activity at human recombinant adenosine A3 receptor expressed in CHO cells assessed as nonradiaoactive DELFIA Eu-GTP binding treated for 15 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50299697(2-(2-Pyridinyl)ethynyl-N6-methyl-5'-N-methylcarbox...)
Affinity DataEC50:  46nMAssay Description:Agonist activity at human recombinant adenosine A3 receptor expressed in CHO cells assessed as nonradiaoactive DELFIA Eu-GTP binding treated for 15 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50299698((2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-(methylamino)...)
Affinity DataEC50:  290nMAssay Description:Agonist activity at human recombinant adenosine A3 receptor expressed in CHO cells assessed as nonradiaoactive DELFIA Eu-GTP binding treated for 15 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50299699((2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-(methoxyamino...)
Affinity DataEC50:  320nMAssay Description:Agonist activity at human recombinant adenosine A3 receptor expressed in CHO cells assessed as nonradiaoactive DELFIA Eu-GTP binding treated for 15 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50299704((2S,3S,4R,5R)-5-(2-chloro-6-(4-iodobenzylamino)-9H...)
Affinity DataEC50:  363nMAssay Description:Agonist activity at human recombinant adenosine A3 receptor expressed in CHO cells assessed as nonradiaoactive DELFIA Eu-GTP binding treated for 15 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50318022(uridine diphosphate trisodium salt | CHEMBL1096401)
Affinity DataEC50:  1.14E+3nMAssay Description:Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of [35S]GTPgammaS binding after 30 mins by rapid filtration ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50306710(CHEMBL1094759 | CHEMBL590494 | ((2R,3S,4R,5R)-3,4-...)
Affinity DataEC50:  945nMAssay Description:Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of [35S]GTPgammaS binding after 30 mins by rapid filtration ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50318024(((2R,3S,4R,5R)-5-(2-chloro-6-(methylamino)-9H-puri...)
Affinity DataEC50:  11nMAssay Description:Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of [35S]GTPgammaS binding after 30 mins by rapid filtration ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50318025(((2R,3S,4R,5R)-5-(6-chloro-4-(methylamino)-1H-imid...)
Affinity DataEC50:  1.70nMAssay Description:Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of [35S]GTPgammaS binding after 30 mins by rapid filtration ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50318026(((2R,3S,4R,5R)-5-(6-(cyclopentylamino)-9H-purin-9-...)
Affinity DataEC50:  1.40nMAssay Description:Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of [35S]GTPgammaS binding after 30 mins by rapid filtration ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50318027(((2R,3S,4R,5R)-5-(6-amino-2-(phenylethynyl)-9H-pur...)
Affinity DataEC50:  0.0360nMAssay Description:Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of [35S]GTPgammaS binding after 30 mins by rapid filtration ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM21220(CHEMBL464859 | N-Ethylcarboxamidoadenosine | Adeno...)
Affinity DataEC50:  2.40E+3nMAssay Description:Receptor stimulated adenylyl cyclase activity in CHO cells expressing human recombinant Adenosine A2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50366686(CHEMBL610346 | CHEMBL3350496)
Affinity DataEC50: >1.00E+5nMAssay Description:Receptor stimulated adenylyl cyclase activity in CHO cells expressing human recombinant Adenosine A2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50366688(CHEMBL2181966 | BDBM50397720 | CHEMBL610640)
Affinity DataEC50: >1.00E+5nMAssay Description:Receptor stimulated adenylyl cyclase activity in CHO cells expressing human recombinant Adenosine A2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50366687(CHEMBL611516 | CHEMBL3350497)
Affinity DataEC50: >1.00E+5nMAssay Description:Receptor stimulated adenylyl cyclase activity in CHO cells expressing human recombinant Adenosine A2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50453224(CHEMBL410873 | 2-(l-hexyn-l-yl)-adenosine-5'-N-met...)
Affinity DataEC50:  105nMAssay Description:Maximal NECA stimulation of adenylate cyclase via adenosine A2 receptor in human platelet membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50368347(CHEMBL610655)
Affinity DataEC50:  388nMAssay Description:Maximal NECA stimulation of adenylate cyclase via A2 receptors in human platelet membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50119168((2R,3R,4S,5R)-2-(6-Amino-2-hex-1-ynyl-purin-9-yl)-...)
Affinity DataEC50:  128nMAssay Description:Maximal NECA stimulation of adenylate cyclase via adenosine A2 receptor in human platelet membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50453222(CHEMBL2113509)
Affinity DataEC50:  62nMAssay Description:Binding affinity against Adenosine A2 receptor from rat striatal membranes with 50 nM CPA using [3H]-NECAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50453216(CHEMBL2113496 | 2-(l-hexyn-l-yl)adenosine (8, YT-1...)
Affinity DataEC50:  681nMAssay Description:Maximal NECA stimulation of adenylate cyclase via adenosine A2 receptor in human platelet membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50453221(CHEMBL2113510)
Affinity DataEC50:  127nMAssay Description:Maximal NECA stimulation of adenylate cyclase via adenosine A2 receptor in human platelet membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50368346(CHEMBL608008)
Affinity DataEC50:  585nMAssay Description:Maximal NECA stimulation of adenylate cyclase via A2 receptors in human platelet membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50453223(CHEMBL2113507)
Affinity DataEC50:  414nMAssay Description:Maximal NECA stimulation of adenylate cyclase via adenosine A2 receptor in human platelet membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50453359(CHEMBL2113409)
Affinity DataEC50:  153nMAssay Description:Negative chronotropic activity via A1 Adenosine receptor was tested in spontaneously beating rat atriaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50453224(CHEMBL410873 | 2-(l-hexyn-l-yl)-adenosine-5'-N-met...)
Affinity DataEC50: >1.00E+4nMAssay Description:Negative chronotropic activity via A1 Adenosine receptor was tested in spontaneously beating rat atriaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50453346(CHEMBL2113449)
Affinity DataEC50:  167nMAssay Description:Negative chronotropic activity via A1 Adenosine receptor was tested in spontaneously beating rat atriaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50453364(CHEMBL2113413)
Affinity DataEC50: >1.00E+4nMAssay Description:Negative chronotropic activity via A1 Adenosine receptor was tested in spontaneously beating rat atriaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50453363(CHEMBL2113412)
Affinity DataEC50:  2.52E+3nMAssay Description:Negative chronotropic activity via A1 Adenosine receptor was tested in spontaneously beating rat atriaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50453361(CHEMBL2113411)
Affinity DataEC50: >1.00E+4nMAssay Description:Negative chronotropic activity via A1 Adenosine receptor was tested in spontaneously beating rat atriaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50453360(CHEMBL2113410)
Affinity DataEC50:  657nMAssay Description:Negative chronotropic activity via A1 Adenosine receptor was tested in spontaneously beating rat atriaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50453354(CHEMBL2113417)
Affinity DataEC50: >1.00E+4nMAssay Description:Negative chronotropic activity via A1 Adenosine receptor was tested in spontaneously beating rat atriaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50453366(CHEMBL2113414)
Affinity DataEC50: >1.00E+4nMAssay Description:Negative chronotropic activity via A1 Adenosine receptor was tested in spontaneously beating rat atriaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50453348(CHEMBL2113486)
Affinity DataEC50: >1.00E+4nMAssay Description:Negative chronotropic activity for A1 Adenosine receptor in spontaneously beating rat atriaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50453352(CHEMBL2113416)
Affinity DataEC50: >1.00E+4nMAssay Description:Negative chronotropic activity for A1 Adenosine receptor in spontaneously beating rat atriaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50453358(CHEMBL2113399)
Affinity DataEC50:  2.43E+3nMAssay Description:Negative chronotropic activity via A1 Adenosine receptor was tested in spontaneously beating rat atriaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50453367(CHEMBL2113402)
Affinity DataEC50:  2.37E+3nMAssay Description:Negative chronotropic activity via A1 Adenosine receptor was tested in spontaneously beating rat atriaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50453350(CHEMBL2113482)
Affinity DataEC50:  332nMAssay Description:Negative chronotropic activity via A1 Adenosine receptor was tested in spontaneously beating rat atriaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50453349(CHEMBL2113483)
Affinity DataEC50:  84nMAssay Description:Negative chronotropic activity via A1 Adenosine receptor was tested in spontaneously beating rat atriaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50453362(CHEMBL2113403)
Affinity DataEC50:  730nMAssay Description:Negative chronotropic activity via A1 Adenosine receptor was tested in spontaneously beating rat atriaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50453356(CHEMBL2113405)
Affinity DataEC50: >1.00E+4nMAssay Description:Negative chronotropic activity via A1 Adenosine receptor was tested in spontaneously beating rat atriaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50453355(CHEMBL2113408)
Affinity DataEC50:  6.05E+3nMAssay Description:Negative chronotropic activity via A1 Adenosine receptor was tested in spontaneously beating rat atriaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM21220(CHEMBL464859 | N-Ethylcarboxamidoadenosine | Adeno...)
Affinity DataEC50:  55nMAssay Description:Negative chronotropic activity via A1 Adenosine receptor was tested in spontaneously beating rat atriaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50453353(CHEMBL2113407)
Affinity DataEC50: >1.00E+4nMAssay Description:Negative chronotropic activity via A1 Adenosine receptor was tested in spontaneously beating rat atriaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50453351(CHEMBL2113485)
Affinity DataEC50: >1.00E+4nMAssay Description:Negative chronotropic activity via A1 Adenosine receptor was tested in spontaneously beating rat atriaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
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