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TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Human)
Burnham Institute For Medical Research

LigandPNGBDBM25127((2E)-3-{3-chloro-4-[3-(3,3-dimethylbut-1-yn-1-yl)-...)
Affinity DataIC50: 450nMpH: 6.0 T: 2°CAssay Description:The phosphatase-catalyzed hydrolysis of 6,8-difluoro-4-methylumbelliferyl phosphate was assayed in the presence of each test compound. The fluorescen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProtein tyrosine phosphatase receptor type C-associated protein(Human)
Burnham Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50212333(5-[3'-(1-adamantyl)-2-chloro-4'-hydroxy-4-biphenyl...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of CD45 PTP by fluorescence spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Burnham Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50212333(5-[3'-(1-adamantyl)-2-chloro-4'-hydroxy-4-biphenyl...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of SHP2 PTP by fluorescence spectroscopyMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Human)
Burnham Institute For Medical Research

LigandPNGBDBM25124((2E)-3-{4-[3-(adamantan-1-yl)-4-aminophenyl]-3-chl...)
Affinity DataIC50: 1.83E+3nMpH: 6.0 T: 2°CAssay Description:The phosphatase-catalyzed hydrolysis of 6,8-difluoro-4-methylumbelliferyl phosphate was assayed in the presence of each test compound. The fluorescen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Human)
Burnham Institute For Medical Research

LigandPNGBDBM25122((2E)-3-{4-[3-(adamantan-1-yl)-4-hydroxyphenyl]-3-c...)
Affinity DataIC50: 2.10E+3nMpH: 6.0 T: 2°CAssay Description:The phosphatase-catalyzed hydrolysis of 6,8-difluoro-4-methylumbelliferyl phosphate was assayed in the presence of each test compound. The fluorescen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Human)
Burnham Institute For Medical Research

LigandPNGBDBM25125((2E)-3-{4-[3-(adamantan-1-yl)-4-fluorophenyl]-3-ch...)
Affinity DataIC50: 2.11E+3nMpH: 6.0 T: 2°CAssay Description:The phosphatase-catalyzed hydrolysis of 6,8-difluoro-4-methylumbelliferyl phosphate was assayed in the presence of each test compound. The fluorescen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Burnham Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50212331(5-[1-(3'-adamantan-1-yl-2-chloro-4'-hydroxy-biphen...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of SHP2 PTP by fluorescence spectroscopyMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Human)
Burnham Institute For Medical Research

LigandPNGBDBM25131((2E)-3-{3-chloro-4-[3-(3,5-dimethyladamantan-1-yl)...)
Affinity DataIC50: 2.27E+3nMpH: 6.0 T: 2°CAssay Description:The phosphatase-catalyzed hydrolysis of 6,8-difluoro-4-methylumbelliferyl phosphate was assayed in the presence of each test compound. The fluorescen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProtein tyrosine phosphatase receptor type C-associated protein(Human)
Burnham Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50212331(5-[1-(3'-adamantan-1-yl-2-chloro-4'-hydroxy-biphen...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of CD45 PTP by fluorescence spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Human)
Burnham Institute For Medical Research

LigandPNGBDBM25129((2E)-3-[3-chloro-4-(4-hydroxy-3-{tricyclo[3.3.1.0^...)
Affinity DataIC50: 3.91E+3nMpH: 6.0 T: 2°CAssay Description:The phosphatase-catalyzed hydrolysis of 6,8-difluoro-4-methylumbelliferyl phosphate was assayed in the presence of each test compound. The fluorescen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Human)
Burnham Institute For Medical Research

LigandPNGBDBM25123((2E)-3-{4-[3-(adamantan-1-yl)-4-acetamidophenyl]-3...)
Affinity DataIC50: 4.55E+3nMpH: 6.0 T: 2°CAssay Description:The phosphatase-catalyzed hydrolysis of 6,8-difluoro-4-methylumbelliferyl phosphate was assayed in the presence of each test compound. The fluorescen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Human)
Burnham Institute For Medical Research

LigandPNGBDBM25133((2E)-3-{3-chloro-4-[3-(3-ethylpentan-3-yl)-4-hydro...)
Affinity DataIC50: 5.37E+3nMpH: 6.0 T: 2°CAssay Description:The phosphatase-catalyzed hydrolysis of 6,8-difluoro-4-methylumbelliferyl phosphate was assayed in the presence of each test compound. The fluorescen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Human)
Burnham Institute For Medical Research

LigandPNGBDBM25130((2E)-3-{3-chloro-4-[4-hydroxy-3-(1-methylcyclohexy...)
Affinity DataIC50: 6.40E+3nMpH: 6.0 T: 2°CAssay Description:The phosphatase-catalyzed hydrolysis of 6,8-difluoro-4-methylumbelliferyl phosphate was assayed in the presence of each test compound. The fluorescen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Human)
Burnham Institute For Medical Research

LigandPNGBDBM25132((2E)-3-{3-chloro-4-[4-hydroxy-3-(2-methyl-1,3-dith...)
Affinity DataIC50: 1.02E+4nMpH: 6.0 T: 2°CAssay Description:The phosphatase-catalyzed hydrolysis of 6,8-difluoro-4-methylumbelliferyl phosphate was assayed in the presence of each test compound. The fluorescen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Human)
Burnham Institute For Medical Research

LigandPNGBDBM25128((2E)-3-{3-chloro-4-[3-(2,6-dimethylphenyl)-4-hydro...)
Affinity DataIC50: 1.99E+4nMpH: 6.0 T: 2°CAssay Description:The phosphatase-catalyzed hydrolysis of 6,8-difluoro-4-methylumbelliferyl phosphate was assayed in the presence of each test compound. The fluorescen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Human)
Burnham Institute For Medical Research

LigandPNGBDBM25126((2E)-3-[3-chloro-4-(4-fluorophenyl)phenyl]prop-2-e...)
Affinity DataIC50: 5.00E+5nMpH: 6.0 T: 2°CAssay Description:The phosphatase-catalyzed hydrolysis of 6,8-difluoro-4-methylumbelliferyl phosphate was assayed in the presence of each test compound. The fluorescen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed