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TargetPotassium channel subfamily K member 2(Human)
Korea Institute of Science and Technology

LigandPNGBDBM60939(I-NBP)
Affinity DataEC50:  60nMpH: 7.3 T: 2°CAssay Description:The hTREK1 stable cell lines were seeded at a density of 10 000 cells/well in a 12-well plate. Whole-cell membrane currents were amplified using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2016
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 2(Human)
Korea Institute of Science and Technology

LigandPNGBDBM50026066(Penfluridol | PENFLURIDOL1-[4,4-Bis-(4-fluoro-phen...)
Affinity DataEC50:  187nMpH: 7.3 T: 2°CAssay Description:The hTREK1 stable cell lines were seeded at a density of 10 000 cells/well in a 12-well plate. Whole-cell membrane currents were amplified using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2016
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 2(Human)
Korea Institute of Science and Technology

LigandPNGBDBM26948(CHEMBL46516 | cid_3396 | FLUSPIRILENE | 8-[4,4-bis...)
Affinity DataEC50:  232nMpH: 7.3 T: 2°CAssay Description:The hTREK1 stable cell lines were seeded at a density of 10 000 cells/well in a 12-well plate. Whole-cell membrane currents were amplified using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2016
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 2(Human)
Korea Institute of Science and Technology

LigandPNGBDBM50334150(1-(1-(4,4-bis(4-fluorophenyl)butyl)piperidin-4-yl)...)
Affinity DataEC50:  354nMpH: 7.3 T: 2°CAssay Description:The hTREK1 stable cell lines were seeded at a density of 10 000 cells/well in a 12-well plate. Whole-cell membrane currents were amplified using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2016
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 2(Human)
Korea Institute of Science and Technology

LigandPNGBDBM50088383(CHEBI:2668 | Amlodipine | Norvasc)
Affinity DataEC50:  430nMpH: 7.3 T: 2°CAssay Description:The hTREK1 stable cell lines were seeded at a density of 10 000 cells/well in a 12-well plate. Whole-cell membrane currents were amplified using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2016
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 2(Human)
Korea Institute of Science and Technology

LigandPNGBDBM50117922(CHEMBL45816 | Methoxy-acetic acid 2-(2-{[3-(1H-ben...)
Affinity DataEC50:  500nMpH: 7.3 T: 2°CAssay Description:The hTREK1 stable cell lines were seeded at a density of 10 000 cells/well in a 12-well plate. Whole-cell membrane currents were amplified using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2016
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 2(Human)
Korea Institute of Science and Technology

LigandPNGBDBM50453799(Niguldipine)
Affinity DataEC50:  750nMpH: 7.3 T: 2°CAssay Description:The hTREK1 stable cell lines were seeded at a density of 10 000 cells/well in a 12-well plate. Whole-cell membrane currents were amplified using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2016
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 2(Human)
Korea Institute of Science and Technology

LigandPNGBDBM86722(CAS_53772-85-3 | NSC_17012 | Flupenthixol, Beta | ...)
Affinity DataEC50:  2.00E+3nMpH: 7.3 T: 2°CAssay Description:The hTREK1 stable cell lines were seeded at a density of 10 000 cells/well in a 12-well plate. Whole-cell membrane currents were amplified using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2016
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 2(Human)
Korea Institute of Science and Technology

LigandPNGBDBM50017702(cid_6365505 | 1-(bis(4-fluorophenyl)methyl)-4-cinn...)
Affinity DataEC50:  2.48E+3nMpH: 7.3 T: 2°CAssay Description:The hTREK1 stable cell lines were seeded at a density of 10 000 cells/well in a 12-well plate. Whole-cell membrane currents were amplified using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2016
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 2(Human)
Korea Institute of Science and Technology

LigandPNGBDBM50408507(Chlorpromazine sulfoxide | CHLOROPROMAZINE SULFOXI...)
Affinity DataEC50:  2.70E+3nMpH: 7.3 T: 2°CAssay Description:The hTREK1 stable cell lines were seeded at a density of 10 000 cells/well in a 12-well plate. Whole-cell membrane currents were amplified using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2016
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 2(Human)
Korea Institute of Science and Technology

LigandPNGBDBM50066430(CHEMBL28854 | 2-(4-Methyl-piperazin-1-yl)-5-(2,3,5...)
Affinity DataEC50:  4.00E+3nMpH: 7.3 T: 2°CAssay Description:The hTREK1 stable cell lines were seeded at a density of 10 000 cells/well in a 12-well plate. Whole-cell membrane currents were amplified using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2016
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 2(Human)
Korea Institute of Science and Technology

LigandPNGBDBM78433(2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...)
Affinity DataEC50:  4.70E+3nMpH: 7.3 T: 2°CAssay Description:The hTREK1 stable cell lines were seeded at a density of 10 000 cells/well in a 12-well plate. Whole-cell membrane currents were amplified using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2016
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 2(Human)
Korea Institute of Science and Technology

LigandPNGBDBM85675(CHEMBL321585 | Anandamide + PMSF)
Affinity DataEC50:  5.10E+3nMpH: 7.3 T: 2°CAssay Description:The hTREK1 stable cell lines were seeded at a density of 10 000 cells/well in a 12-well plate. Whole-cell membrane currents were amplified using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2016
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 2(Human)
Korea Institute of Science and Technology

LigandPNGBDBM50053408(Haldol | Haldol Dec | Haloperidol Decanoate | R-13...)
Affinity DataEC50:  5.50E+3nMpH: 7.3 T: 2°CAssay Description:The hTREK1 stable cell lines were seeded at a density of 10 000 cells/well in a 12-well plate. Whole-cell membrane currents were amplified using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2016
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 2(Human)
Korea Institute of Science and Technology

LigandPNGBDBM50101817(CHEBI:7565 | Adalat | Adalat Cc | Afeditab Cr | BA...)
Affinity DataEC50:  8.18E+3nMpH: 7.3 T: 2°CAssay Description:The hTREK1 stable cell lines were seeded at a density of 10 000 cells/well in a 12-well plate. Whole-cell membrane currents were amplified using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2016
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 2(Human)
Korea Institute of Science and Technology

LigandPNGBDBM50254790(NORFLUOXETINE | CHEMBL465123 | (S)-Norfluoxetine)
Affinity DataEC50:  9.00E+3nMpH: 7.3 T: 2°CAssay Description:The hTREK1 stable cell lines were seeded at a density of 10 000 cells/well in a 12-well plate. Whole-cell membrane currents were amplified using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2016
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 2(Human)
Korea Institute of Science and Technology

LigandPNGBDBM81875(Fluoxetine-R-(-))
Affinity DataEC50:  1.90E+4nMpH: 7.3 T: 2°CAssay Description:The hTREK1 stable cell lines were seeded at a density of 10 000 cells/well in a 12-well plate. Whole-cell membrane currents were amplified using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2016
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 2(Human)
Korea Institute of Science and Technology

LigandPNGBDBM22871(13-chloro-10-(4-methylpiperazin-1-yl)-2-oxa-9-azat...)
Affinity DataEC50:  1.97E+4nMpH: 7.3 T: 2°CAssay Description:The hTREK1 stable cell lines were seeded at a density of 10 000 cells/well in a 12-well plate. Whole-cell membrane currents were amplified using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2016
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 2(Human)
Korea Institute of Science and Technology

LigandPNGBDBM190405(US9180183, Quinidine)
Affinity DataEC50:  2.41E+4nMpH: 7.3 T: 2°CAssay Description:The hTREK1 stable cell lines were seeded at a density of 10 000 cells/well in a 12-well plate. Whole-cell membrane currents were amplified using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2016
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 2(Human)
Korea Institute of Science and Technology

LigandPNGBDBM181128(US9138393, Diltiazem)
Affinity DataEC50:  2.48E+4nMpH: 7.3 T: 2°CAssay Description:The hTREK1 stable cell lines were seeded at a density of 10 000 cells/well in a 12-well plate. Whole-cell membrane currents were amplified using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2016
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 2(Human)
Korea Institute of Science and Technology

LigandPNGBDBM50012957(1-((p-(2-(5-chloro-o-anisamido)ethyl)phenyl)sulfon...)
Affinity DataEC50:  6.40E+4nMpH: 7.3 T: 2°CAssay Description:The hTREK1 stable cell lines were seeded at a density of 10 000 cells/well in a 12-well plate. Whole-cell membrane currents were amplified using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2016
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 2(Human)
Korea Institute of Science and Technology

LigandPNGBDBM50350790(Bupivacaine | BUPIVACAINE HYDROCHLORIDE | SAMPL3, ...)
Affinity DataEC50:  1.13E+5nMpH: 7.3 T: 2°CAssay Description:The hTREK1 stable cell lines were seeded at a density of 10 000 cells/well in a 12-well plate. Whole-cell membrane currents were amplified using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2016
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 2(Human)
Korea Institute of Science and Technology

LigandPNGBDBM10849(CHEMBL113 | 1,3,7-trimethyl-3,7-dihydropurine-2,6-...)
Affinity DataEC50:  3.77E+5nMpH: 7.3 T: 2°CAssay Description:The hTREK1 stable cell lines were seeded at a density of 10 000 cells/well in a 12-well plate. Whole-cell membrane currents were amplified using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2016
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 2(Human)
Korea Institute of Science and Technology

LigandPNGBDBM82053(8-(2-Furyl)theophylline | US9138393, Theophylline ...)
Affinity DataEC50:  4.86E+5nMpH: 7.3 T: 2°CAssay Description:The hTREK1 stable cell lines were seeded at a density of 10 000 cells/well in a 12-well plate. Whole-cell membrane currents were amplified using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2016
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 2(Human)
Korea Institute of Science and Technology

LigandPNGBDBM50027886(N-[(butylamino)carbonyl]-4-methylbenzenesulfonamid...)
Affinity DataEC50:  7.84E+5nMpH: 7.3 T: 2°CAssay Description:The hTREK1 stable cell lines were seeded at a density of 10 000 cells/well in a 12-well plate. Whole-cell membrane currents were amplified using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2016
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 2(Human)
Korea Institute of Science and Technology

LigandPNGBDBM10458(pyridin-4-amine | CHEMBL284348 | 4-Aminopyridine 1...)
Affinity DataEC50:  2.75E+6nMpH: 7.3 T: 2°CAssay Description:The hTREK1 stable cell lines were seeded at a density of 10 000 cells/well in a 12-well plate. Whole-cell membrane currents were amplified using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2016
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Mouse)
Beijing Foreland Biopharma

US Patent
LigandPNGBDBM221913(US9315492, 10)
Affinity DataEC50:  77nMT: 2°CAssay Description:Assay procedures: OCC culture solution was preheated in water tank at 37° C. Cells were taken out from liquor nitrogen tank, left on the dry-ice, and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
Go to US Patent

TargetSphingosine 1-phosphate receptor 1(Mouse)
Beijing Foreland Biopharma

US Patent
LigandPNGBDBM221914(US9315492, 11)
Affinity DataEC50:  3.10nMT: 2°CAssay Description:Assay procedures: OCC culture solution was preheated in water tank at 37° C. Cells were taken out from liquor nitrogen tank, left on the dry-ice, and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
Go to US Patent

TargetSphingosine 1-phosphate receptor 1(Mouse)
Beijing Foreland Biopharma

US Patent
LigandPNGBDBM221916(US9315492, 15)
Affinity DataEC50:  27nMT: 2°CAssay Description:Assay procedures: OCC culture solution was preheated in water tank at 37° C. Cells were taken out from liquor nitrogen tank, left on the dry-ice, and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
Go to US Patent

TargetSphingosine 1-phosphate receptor 1(Mouse)
Beijing Foreland Biopharma

US Patent
LigandPNGBDBM221932(US9315492, 22)
Affinity DataEC50:  8nMT: 2°CAssay Description:Assay procedures: OCC culture solution was preheated in water tank at 37° C. Cells were taken out from liquor nitrogen tank, left on the dry-ice, and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
Go to US Patent

TargetSphingosine 1-phosphate receptor 1(Mouse)
Beijing Foreland Biopharma

US Patent
LigandPNGBDBM221923(US9315492, 24)
Affinity DataEC50:  354nMT: 2°CAssay Description:Assay procedures: OCC culture solution was preheated in water tank at 37° C. Cells were taken out from liquor nitrogen tank, left on the dry-ice, and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
Go to US Patent

TargetSphingosine 1-phosphate receptor 1(Mouse)
Beijing Foreland Biopharma

US Patent
LigandPNGBDBM221926(US9315492, 27)
Affinity DataEC50:  20nMT: 2°CAssay Description:Assay procedures: OCC culture solution was preheated in water tank at 37° C. Cells were taken out from liquor nitrogen tank, left on the dry-ice, and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
Go to US Patent

TargetSphingosine 1-phosphate receptor 1(Mouse)
Beijing Foreland Biopharma

US Patent
LigandPNGBDBM221928(US9315492, 29)
Affinity DataEC50:  9.90nMT: 2°CAssay Description:Assay procedures: OCC culture solution was preheated in water tank at 37° C. Cells were taken out from liquor nitrogen tank, left on the dry-ice, and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
Go to US Patent

TargetSphingosine 1-phosphate receptor 1(Mouse)
Beijing Foreland Biopharma

US Patent
LigandPNGBDBM221929(US9315492, 31 | US9315492, 32)
Affinity DataEC50:  14.3nMT: 2°CAssay Description:Assay procedures: OCC culture solution was preheated in water tank at 37° C. Cells were taken out from liquor nitrogen tank, left on the dry-ice, and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
Go to US Patent

TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 gamma(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM690795(US20240277852, Compound 1)
Affinity DataKd:  36nMAssay Description:The inhibitory activity of the compounds were evaluated using KINOMEscan PIP5K2B (also known as PIP4K2B) and KINOMEscan PIP5K2C (also known as PIP4k2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
Go to US Patent

TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM690795(US20240277852, Compound 1)
Affinity DataKd: >1.00E+4nMAssay Description:The inhibitory activity of the compounds were evaluated using KINOMEscan PIP5K2B (also known as PIP4K2B) and KINOMEscan PIP5K2C (also known as PIP4k2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
Go to US Patent

TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 gamma(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM691383(US20240277852, Compound 2)
Affinity DataKd:  56nMAssay Description:The inhibitory activity of the compounds were evaluated using KINOMEscan PIP5K2B (also known as PIP4K2B) and KINOMEscan PIP5K2C (also known as PIP4k2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
Go to US Patent

TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM691383(US20240277852, Compound 2)
Affinity DataKd: >1.00E+4nMAssay Description:The inhibitory activity of the compounds were evaluated using KINOMEscan PIP5K2B (also known as PIP4K2B) and KINOMEscan PIP5K2C (also known as PIP4k2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
Go to US Patent

TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 gamma(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM691384(US20240277852, Compound 3)
Affinity DataKd:  29nMAssay Description:The inhibitory activity of the compounds were evaluated using KINOMEscan PIP5K2B (also known as PIP4K2B) and KINOMEscan PIP5K2C (also known as PIP4k2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
Go to US Patent

TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM691384(US20240277852, Compound 3)
Affinity DataKd: >1.00E+4nMAssay Description:The inhibitory activity of the compounds were evaluated using KINOMEscan PIP5K2B (also known as PIP4K2B) and KINOMEscan PIP5K2C (also known as PIP4k2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
Go to US Patent

TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 gamma(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM691385(US20240277852, Compound 4)
Affinity DataKd:  64nMAssay Description:The inhibitory activity of the compounds were evaluated using KINOMEscan PIP5K2B (also known as PIP4K2B) and KINOMEscan PIP5K2C (also known as PIP4k2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
Go to US Patent

TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM691385(US20240277852, Compound 4)
Affinity DataKd: >1.00E+4nMAssay Description:The inhibitory activity of the compounds were evaluated using KINOMEscan PIP5K2B (also known as PIP4K2B) and KINOMEscan PIP5K2C (also known as PIP4k2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
Go to US Patent

TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 gamma(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM691386(US20240277852, Compound 5)
Affinity DataKd:  46nMAssay Description:The inhibitory activity of the compounds were evaluated using KINOMEscan PIP5K2B (also known as PIP4K2B) and KINOMEscan PIP5K2C (also known as PIP4k2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
Go to US Patent

TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 gamma(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM691387(US20240277852, Compound 6)
Affinity DataKd:  43nMAssay Description:The inhibitory activity of the compounds were evaluated using KINOMEscan PIP5K2B (also known as PIP4K2B) and KINOMEscan PIP5K2C (also known as PIP4k2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
Go to US Patent

TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 gamma(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM691388(US20240277852, Compound 7)
Affinity DataKd:  150nMAssay Description:The inhibitory activity of the compounds were evaluated using KINOMEscan PIP5K2B (also known as PIP4K2B) and KINOMEscan PIP5K2C (also known as PIP4k2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
Go to US Patent

TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 gamma(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM691389(US20240277852, Compound 8)
Affinity DataKd:  270nMAssay Description:The inhibitory activity of the compounds were evaluated using KINOMEscan PIP5K2B (also known as PIP4K2B) and KINOMEscan PIP5K2C (also known as PIP4k2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
Go to US Patent

TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 gamma(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM691390(US20240277852, Compound 9)
Affinity DataKd:  1.40E+3nMAssay Description:The inhibitory activity of the compounds were evaluated using KINOMEscan PIP5K2B (also known as PIP4K2B) and KINOMEscan PIP5K2C (also known as PIP4k2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
Go to US Patent

TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM691390(US20240277852, Compound 9)
Affinity DataKd: >1.00E+4nMAssay Description:The inhibitory activity of the compounds were evaluated using KINOMEscan PIP5K2B (also known as PIP4K2B) and KINOMEscan PIP5K2C (also known as PIP4k2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
Go to US Patent

TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 gamma(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM691391(US20240277852, Compound 10)
Affinity DataKd:  65nMAssay Description:The inhibitory activity of the compounds were evaluated using KINOMEscan PIP5K2B (also known as PIP4K2B) and KINOMEscan PIP5K2C (also known as PIP4k2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
Go to US Patent

TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 gamma(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM691392(US20240277852, Compound 11)
Affinity DataKd:  7.20nMAssay Description:The inhibitory activity of the compounds were evaluated using KINOMEscan PIP5K2B (also known as PIP4K2B) and KINOMEscan PIP5K2C (also known as PIP4k2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
Go to US Patent

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