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TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50471498(CHEMBL150450)
Affinity DataKi:  0.240nMAssay Description:Binding affinity against Muscarinic acetylcholine receptors using [3H]oxotremorine-M as radioligand in rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50471487(CHEMBL436075)
Affinity DataKi:  0.330nMAssay Description:Binding affinity against Muscarinic acetylcholine receptors using [3H]oxotremorine-M as radioligand in rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50471494(CHEMBL153723)
Affinity DataKi:  0.360nMAssay Description:Binding affinity against Muscarinic acetylcholine receptors using [3H]oxotremorine-M as radioligand in rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50471485(Vedaclidine)
Affinity DataKi:  0.400nMAssay Description:Binding affinity against Muscarinic acetylcholine receptors using [3H]oxotremorine-M as radioligand in rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50471499(CHEMBL345774)
Affinity DataKi:  0.400nMAssay Description:Binding affinity against Muscarinic acetylcholine receptor using [3H]oxotremorine-M as radioligand in rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50471492(CHEMBL150293)
Affinity DataKi:  0.420nMAssay Description:Binding affinity against Muscarinic acetylcholine receptors using [3H]oxotremorine-M as radioligand in rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50471495(CHEMBL153478)
Affinity DataKi:  0.440nMAssay Description:Binding affinity against Muscarinic acetylcholine receptors using [3H]oxotremorine-M as radioligand in rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50471486(CHEMBL343731)
Affinity DataKi:  0.450nMAssay Description:Binding affinity against Muscarinic acetylcholine receptors using [3H]oxotremorine-M as radioligand in rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50033155(3-(3-Butylsulfanyl-pyrazin-2-yl)-1-aza-bicyclo[2.2...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity against Muscarinic acetylcholine receptors using [3H]oxotremorine-M as radioligand in rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50403547(ATROPEN | ATROPINE)
Affinity DataKi:  0.900nMAssay Description:Binding affinity against Muscarinic acetylcholine receptors using [3H]oxotremorine-M as radioligand in rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50471491(CHEMBL357279)
Affinity DataKi:  0.910nMAssay Description:Binding affinity against Muscarinic acetylcholine receptors using [3H]oxotremorine-M as radioligand in rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50070725(CHEMBL318403)
Affinity DataKi:  1nMAssay Description:Binding affinity against Muscarinic acetylcholine receptors using [3H]oxotremorine-M as radioligand in rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50003351(3-(4-butoxy-1,2,5-thiadiazol-3-yl)-1-methyl-1,2,5,...)
Affinity DataKi:  1.40nMAssay Description:Binding affinity against Muscarinic acetylcholine receptors using [3H]oxotremorine-M as radioligand in rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50471489(CHEMBL153150)
Affinity DataKi:  3nMAssay Description:Binding affinity against Muscarinic acetylcholine receptors using [3H]oxotremorine-M as radioligand in rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50471496(CHEMBL153031)
Affinity DataKi:  3.5nMAssay Description:Binding affinity against Muscarinic acetylcholine receptors using [3H]oxotremorine-M as radioligand in rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50033151(3-(3-Hexylsulfanyl-pyrazin-2-yl)-1-aza-bicyclo[2.2...)
Affinity DataKi:  4nMAssay Description:Binding affinity against Muscarinic acetylcholine receptors using [3H]oxotremorine-M as radioligand in rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50471497(CHEMBL150501)
Affinity DataKi:  9.60nMAssay Description:Binding affinity against Muscarinic acetylcholine receptors using [3H]oxotremorine-M as radioligand in rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50471488(CHEMBL152892)
Affinity DataKi:  10nMAssay Description:Binding affinity against Muscarinic acetylcholine receptors using [3H]oxotremorine-M as radioligand in rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50471493(CHEMBL152919)
Affinity DataKi:  18nMAssay Description:Binding affinity against Muscarinic acetylcholine receptors using [3H]oxotremorine-M as radioligand in rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50471490(CHEMBL154923)
Affinity DataKi:  25nMAssay Description:Binding affinity against Muscarinic acetylcholine receptors using [3H]oxotremorine-M as radioligand in rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50003355(5-(4-Hexylsulfanyl-[1,2,5]thiadiazol-3-yl)-1-methy...)
Affinity DataIC50:  0.00100nMAssay Description:Efficacy at muscarinic acetylcholine receptor M1 measured by the ability to inhibit the electrically stimulated twitch of the rabbit vas deferensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50003363(1-Methyl-5-(4-pentylsulfanyl-[1,2,5]thiadiazol-3-y...)
Affinity DataIC50:  0.00200nMAssay Description:Efficacy at muscarinic acetylcholine receptor M1 measured by the ability to inhibit the electrically stimulated twitch of the rabbit vas deferensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50003366(1-Methyl-5-(4-pentyloxy-[1,2,5]thiadiazol-3-yl)-1,...)
Affinity DataIC50:  0.00400nMAssay Description:Efficacy at muscarinic acetylcholine receptor M1 measured by the ability to inhibit the electrically stimulated twitch of the rabbit vas deferensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50003359(5-(4-Hexyloxy-[1,2,5]thiadiazol-3-yl)-1-methyl-1,2...)
Affinity DataIC50:  0.00800nMAssay Description:Efficacy at muscarinic acetylcholine receptor M1 measured by the ability to inhibit the electrically stimulated twitch of the rabbit vas deferensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50062577(6-(4-Propylsulfanyl-[1,2,5]thiadiazol-3-yloxy)-1-a...)
Affinity DataIC50:  0.380nMAssay Description:Binding affinity for muscarinic acetylcholine receptor M1 using [3H]-oxotremorine-M (Oxo-M) radioligand in rat hippocampus membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50033155(3-(3-Butylsulfanyl-pyrazin-2-yl)-1-aza-bicyclo[2.2...)
Affinity DataIC50:  0.400nMAssay Description:Binding activity against muscarinic acetylcholine receptor M1 in rat brain, using [3H]-Pz as the radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50033155(3-(3-Butylsulfanyl-pyrazin-2-yl)-1-aza-bicyclo[2.2...)
Affinity DataIC50:  0.5nMAssay Description:Binding activity against muscarinic acetylcholine receptor M1 in rat brain, using [3H]OXO-M as the radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50062577(6-(4-Propylsulfanyl-[1,2,5]thiadiazol-3-yloxy)-1-a...)
Affinity DataIC50:  0.550nMAssay Description:Binding affinity for muscarinic acetylcholine receptor M1 using [3H]-Pirenzepine (Pz) radioligand in rat hippocampus membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50062577(6-(4-Propylsulfanyl-[1,2,5]thiadiazol-3-yloxy)-1-a...)
Affinity DataIC50:  0.550nMAssay Description:Binding affinity for muscarinic acetylcholine receptor M1 using [3H]-Pirenzepine (Pz) radioligand in rat hippocampus membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50062595(3-(4-Propylsulfanyl-[1,2,5]thiadiazol-3-yl)-1-aza-...)
Affinity DataIC50:  0.600nMAssay Description:Binding affinity for muscarinic acetylcholine receptor M1 using [3H]-oxotremorine-M (Oxo-M) radioligand in rat hippocampus membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50062595(3-(4-Propylsulfanyl-[1,2,5]thiadiazol-3-yl)-1-aza-...)
Affinity DataIC50:  0.600nMAssay Description:Binding affinity for muscarinic acetylcholine receptor M1 using [3H]-oxotremorine-M (Oxo-M) radioligand in rat hippocampus membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50033162(3-(3-Pentylsulfanyl-pyrazin-2-yl)-1-aza-bicyclo[2....)
Affinity DataIC50:  0.700nMAssay Description:Binding activity against muscarinic acetylcholine receptor M1 in rat brain, using [3H]OXO-M as the radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50070692(CHEMBL99240)
Affinity DataIC50:  0.730nMAssay Description:Binding affinity against muscarinic receptor in rat brain membranes using oxotremorine-M as ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50062570(3-(4-Propylsulfanyl-[1,2,5]thiadiazol-3-yloxy)-1-a...)
Affinity DataIC50:  0.760nMAssay Description:Binding affinity for muscarinic acetylcholine receptor M1 using [3H]-oxotremorine-M (Oxo-M) radioligand in rat hippocampus membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50072214((R)-3-[4-(3-Phenyl-prop-2-ynyloxy)-[1,2,5]thiadiaz...)
Affinity DataIC50:  0.800nMAssay Description:Binding affinity against muscarinic receptor in rat brain membranes using oxotremorine-M as ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50006582(1-Methyl-5-(4-propylsulfanyl-[1,2,5]thiadiazol-3-y...)
Affinity DataIC50:  0.900nMAssay Description:In vitro binding affinity against muscarinic acetylcholine receptor M1 from rat hippocampus, using [3H]-oxotremorine-M (Oxo-M) as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50033162(3-(3-Pentylsulfanyl-pyrazin-2-yl)-1-aza-bicyclo[2....)
Affinity DataIC50:  1.10nMAssay Description:Binding activity against muscarinic acetylcholine receptor M1 in rat brain, using [3H]-Pz as the radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50070735(CHEMBL317324)
Affinity DataIC50:  1.20nMAssay Description:Binding affinity against muscarinic receptor in rat brain membranes using oxotremorine-M as ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50072227((1R,5R,6R)-6-[4-(3-Phenyl-prop-2-ynyloxy)-[1,2,5]t...)
Affinity DataIC50:  1.20nMAssay Description:Binding affinity against muscarinic receptor in rat brain membranes using oxotremorine-M as ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50006572(5-(4-Butylsulfanyl-[1,2,5]thiadiazol-3-yl)-1-methy...)
Affinity DataIC50:  1.30nMAssay Description:In vitro binding affinity against muscarinic acetylcholine receptor M1 from rat hippocampus, using [3H]-pirenzepine (Pz) as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50006572(5-(4-Butylsulfanyl-[1,2,5]thiadiazol-3-yl)-1-methy...)
Affinity DataIC50:  1.30nMAssay Description:In vitro binding affinity against muscarinic acetylcholine receptor M1 from rat hippocampus, using [3H]-pirenzepine (Pz) as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50070647(CHEMBL329924)
Affinity DataIC50:  1.30nMAssay Description:Binding affinity against muscarinic receptor in rat brain membranes using oxotremorine-M as ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50070725(CHEMBL318403)
Affinity DataIC50:  1.30nMAssay Description:Binding affinity against muscarinic receptor in rat brain membranes using oxotremorine-M as ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50003351(3-(4-butoxy-1,2,5-thiadiazol-3-yl)-1-methyl-1,2,5,...)
Affinity DataIC50:  1.40nMAssay Description:In vitro binding affinity against muscarinic acetylcholine receptor M1 from rat hippocampus, using [3H]-oxotremorine-M (Oxo-M) as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50003351(3-(4-butoxy-1,2,5-thiadiazol-3-yl)-1-methyl-1,2,5,...)
Affinity DataIC50:  1.40nMAssay Description:Binding affinity against muscarinic receptor in rat brain membranes using oxotremorine-M as ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50003351(3-(4-butoxy-1,2,5-thiadiazol-3-yl)-1-methyl-1,2,5,...)
Affinity DataIC50:  1.40nMAssay Description:In vitro binding affinity against muscarinic acetylcholine receptor M1 from rat hippocampus, using [3H]-oxotremorine-M (Oxo-M) as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50003351(3-(4-butoxy-1,2,5-thiadiazol-3-yl)-1-methyl-1,2,5,...)
Affinity DataIC50:  1.40nMAssay Description:Displacement of [3H]-oxotremorine-M (Oxo-M) from rat hippocampus muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50003369(1-Methyl-5-(4-propoxy-[1,2,5]thiadiazol-3-yl)-1,2,...)
Affinity DataIC50:  1.60nMAssay Description:In vitro binding affinity against rat hippocampus Muscarinic acetylcholine receptor M1 using [3H]-oxotremorine-M (Oxo-M) as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50003369(1-Methyl-5-(4-propoxy-[1,2,5]thiadiazol-3-yl)-1,2,...)
Affinity DataIC50:  1.60nMAssay Description:In vitro binding affinity against muscarinic acetylcholine receptor M1 from rat hippocampus, using [3H]-pirenzepine (Pz) as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50003369(1-Methyl-5-(4-propoxy-[1,2,5]thiadiazol-3-yl)-1,2,...)
Affinity DataIC50:  1.60nMAssay Description:Binding affinity against muscarinic receptor in rat brain membranes using oxotremorine-M as ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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