Compile Data Set for Download or QSAR
Report error Found 32 with Last Name = 'whitmer' and Initial = 'wl'
LigandPNGBDBM50049730(Epalrestat | 2-(5-(2-methyl-3-phenylallylidene)-4-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of crude aldose reductase of rat lensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
LigandPNGBDBM16312(CHEMBL266497 | (4S)-6-fluoro-2,3-dihydrospiro[1-be...)
Affinity DataIC50: 17nMAssay Description:Compound was tested for inhibitory concentration against rat lens aldose reductase (noncompetitive inhibition type)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
LigandPNGBDBM16312(CHEMBL266497 | (4S)-6-fluoro-2,3-dihydrospiro[1-be...)
Affinity DataIC50: 17nMAssay Description:Inhibition of crude aldose reductase of rat lensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
LigandPNGBDBM50022179((3-Oxo-3H-benzo[f]chromen-1-yl)-acetic acid | CHEM...)
Affinity DataIC50: 20nMAssay Description:Compound was tested for inhibitory concentration against rat lens aldose reductase (noncompetitive inhibition type)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
LigandPNGBDBM50022185((2-Oxo-2H-benzo[h]chromen-4-yl)-acetic acid | CHEM...)
Affinity DataIC50: 140nMAssay Description:Compound was tested for inhibitory concentration against rat lens aldose reductase (noncompetitive inhibition type)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
LigandPNGBDBM50022182((7-Hydroxy-2-oxo-2H-chromen-4-yl)-acetic acid | 7-...)
Affinity DataIC50: 150nMAssay Description:Compound was tested for inhibitory concentration against rat lens aldose reductase (noncompetitive inhibition type)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
LigandPNGBDBM50022174((7-Ethyl-2-oxo-2H-chromen-4-yl)-acetic acid | CHEM...)
Affinity DataIC50: 240nMAssay Description:Compound was tested for inhibitory concentration against rat lens aldose reductase (noncompetitive inhibition type)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
LigandPNGBDBM50022183((5,7-Dihydroxy-2-oxo-2H-chromen-4-yl)-acetic acid ...)
Affinity DataIC50: 260nMAssay Description:Compound was tested for inhibitory concentration against rat lens aldose reductase (noncompetitive inhibition type)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
LigandPNGBDBM50022173((7-methoxy-2-oxo-2H-chromen-4-yl)acetic acid | 7-m...)
Affinity DataIC50: 370nMAssay Description:Compound was tested for inhibitory concentration against rat lens aldose reductase (noncompetitive inhibition type)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
LigandPNGBDBM50022247((4-Methyl-6-nitro-2-oxo-2H-quinolin-1-yl)-acetic a...)
Affinity DataIC50: 450nMAssay Description:Inhibition of crude aldose reductase of rat lensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
LigandPNGBDBM50022171((7-Chloro-2-oxo-2H-chromen-4-yl)-acetic acid | CHE...)
Affinity DataIC50: 560nMAssay Description:Compound was tested for inhibitory concentration against rat lens aldose reductase (noncompetitive inhibition type)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
LigandPNGBDBM50022175((2-Oxo-2H-chromen-4-yl)-acetic acid | CHEMBL274190)
Affinity DataIC50: 600nMAssay Description:Compound was tested for inhibitory concentration against rat lens aldose reductase (noncompetitive inhibition type)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
LigandPNGBDBM50022249((6-Methoxy-2-oxo-2H-quinolin-1-yl)-acetic acid | C...)
Affinity DataIC50: 910nMAssay Description:Inhibition of crude aldose reductase of rat lensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
LigandPNGBDBM16415((1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)acetic...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of crude aldose reductase of rat lensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50022181(3-(7-Methoxy-2-oxo-2H-chromen-4-yl)-propionic acid...)
Affinity DataIC50: 2.10E+3nMAssay Description:Compound was tested for inhibitory concentration against rat lens aldose reductase (noncompetitive inhibition type)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
LigandPNGBDBM50022252((6-Hydroxy-2-oxo-2H-quinolin-1-yl)-acetic acid | C...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of crude aldose reductase of rat lensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
LigandPNGBDBM50022245((8-Hydroxy-2-oxo-2H-quinolin-1-yl)-acetic acid | C...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of crude aldose reductase of rat lensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
LigandPNGBDBM50022187(3-(7-Methoxy-2-oxo-2H-chromen-4-yl)-acrylic acid |...)
Affinity DataIC50: 4.40E+3nMAssay Description:Compound was tested for inhibitory concentration against rat lens aldose reductase (noncompetitive inhibition type)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
LigandPNGBDBM50022246((4-Methyl-2-oxo-2H-quinolin-1-yl)-acetic acid | CH...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of crude aldose reductase of rat lensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
LigandPNGBDBM50022177(2-(7-Hydroxy-2-oxo-2H-chromen-4-yl)-acetamide | CH...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was tested for inhibitory concentration against rat lens aldose reductase (noncompetitive inhibition type)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
LigandPNGBDBM50022184(7,8-dihydroxy-4-methyl-2H-chromen-2-one | 7,8-Dihy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was tested for inhibitory concentration against rat lens aldose reductase (noncompetitive inhibition type)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
LigandPNGBDBM50022188(7-Methoxy-2-oxo-2H-chromene-4-carboxylic acid | CH...)
Affinity DataIC50: 1.10E+4nMAssay Description:Compound was tested for inhibitory concentration against rat lens aldose reductase (noncompetitive inhibition type)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
LigandPNGBDBM50022180(Coumarin derivative, 1b | CHEMBL12252 | 5,7-Dihydr...)
Affinity DataIC50: 1.70E+4nMAssay Description:Compound was tested for inhibitory concentration against rat lens aldose reductase (noncompetitive inhibition type)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
LigandPNGBDBM50022186(naphthalen-1-ylacetic acid | 1-naphthylacetic acid...)
Affinity DataIC50: 3.20E+4nMAssay Description:Compound was tested for inhibitory concentration against rat lens aldose reductase (noncompetitive inhibition type)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
LigandPNGBDBM50022186(naphthalen-1-ylacetic acid | 1-naphthylacetic acid...)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of crude aldose reductase of rat lensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
LigandPNGBDBM50022250(2-(8-Hydroxy-2-oxo-2H-quinolin-1-yl)-propionic aci...)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of crude aldose reductase of rat lensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
LigandPNGBDBM50022172(CHEMBL275000 | cid_5395514 | (7-Hydroxy-2-oxo-2H-c...)
Affinity DataIC50: 3.80E+4nMAssay Description:Compound was tested for inhibitory concentration against rat lens aldose reductase (noncompetitive inhibition type)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
LigandPNGBDBM50022176((7-Acetoxy-2-oxo-2H-chromen-4-yl)-acetic acid | CH...)
Affinity DataIC50: 6.10E+4nMAssay Description:Compound was tested for inhibitory concentration against rat lens aldose reductase (noncompetitive inhibition type)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
LigandPNGBDBM50022178(4-Methyl-7-hydroxycoumarin | 7-Hydroxy-4-methyl-2H...)
Affinity DataIC50: 6.20E+4nMAssay Description:Compound was tested for inhibitory concentration against rat lens aldose reductase (noncompetitive inhibition type)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
LigandPNGBDBM50022251(3-(4-Methyl-2-oxo-2H-quinolin-1-yl)-propionic acid...)
Affinity DataIC50: 1.10E+5nMAssay Description:Inhibition of crude aldose reductase of rat lensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
LigandPNGBDBM50022248(2-(4-Methyl-2-oxo-2H-quinolin-1-yl)-propionic acid...)
Affinity DataIC50: 4.70E+5nMAssay Description:Inhibition of crude aldose reductase of rat lensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
LigandPNGBDBM50022244(2-(6-Methoxy-2-oxo-2H-quinolin-1-yl)-propionic aci...)
Affinity DataIC50: 5.90E+5nMAssay Description:Inhibition of crude aldose reductase of rat lensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed