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TargetProtein kinase C alpha type(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50310131((2-hydroxy-4-(3-isobutyl-5-methylhexylidene)-5-oxo...)
Affinity DataKi:  2.90nMAssay Description:Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50310107((E)-(2-(hydroxymethyl)-4-(8-(nonyloxy)octylidene)-...)
Affinity DataKi:  3.20nMAssay Description:Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50310104((E)-(2-(hydroxymethyl)-4-(16-methoxyhexadecylidene...)
Affinity DataKi:  4.40nMAssay Description:Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50310105((Z)-(2-(hydroxymethyl)-4-(16-methoxyhexadecylidene...)
Affinity DataKi:  5nMAssay Description:Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50310120((E)-(2-(hydroxymethyl)-5-oxo-4-(16-oxohexadecylide...)
Affinity DataKi:  6.40nMAssay Description:Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50310115((E)-(4-(16-hydroxyhexadecylidene)-2-(hydroxymethyl...)
Affinity DataKi:  6.40nMAssay Description:Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50310124((E)-methyl 16-(5-(hydroxymethyl)-2-oxo-5-(pivaloyl...)
Affinity DataKi:  6.80nMAssay Description:Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50310101((Z)-(2-(hydroxymethyl)-5-oxo-4-tetradecylidenetetr...)
Affinity DataKi:  7.20nMAssay Description:Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50310112((E)-(2-(hydroxymethyl)-4-(4-(nonyloxy)butylidene)-...)
Affinity DataKi:  7.40nMAssay Description:Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50310110((E)-(2-(hydroxymethyl)-4-(8-(isopentyloxy)octylide...)
Affinity DataKi:  7.70nMAssay Description:Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50310100((E)-(2-(hydroxymethyl)-5-oxo-4-tetradecylidenetetr...)
Affinity DataKi:  7.80nMAssay Description:Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50310125((E)-(4-(16-(formyloxy)hexadecylidene)-2-(hydroxyme...)
Affinity DataKi:  8nMAssay Description:Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50310106((E)-(2-(hydroxymethyl)-5-oxo-4-(8-(pentyloxy)octyl...)
Affinity DataKi:  8.10nMAssay Description:Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50310103((E)-(2-(hydroxymethyl)-4-(12-methoxydodecylidene)-...)
Affinity DataKi:  8.20nMAssay Description:Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50310116((Z)-(4-(16-hydroxyhexadecylidene)-2-(hydroxymethyl...)
Affinity DataKi:  8.20nMAssay Description:Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50310130((E)-(4-(16-acetamidohexadecylidene)-2-(hydroxymeth...)
Affinity DataKi:  8.30nMAssay Description:Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50310126((E)-(4-(16-acetoxyhexadecylidene)-2-(hydroxymethyl...)
Affinity DataKi:  9.30nMAssay Description:Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50310111((E)-(4-(8-(cyclopentyloxy)octylidene)-2-(hydroxyme...)
Affinity DataKi:  10nMAssay Description:Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50310127((E)-16-(5-(hydroxymethyl)-2-oxo-5-(pivaloyloxymeth...)
Affinity DataKi:  11nMAssay Description:Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50310121((Z)-(2-(hydroxymethyl)-5-oxo-4-(16-oxohexadecylide...)
Affinity DataKi:  11nMAssay Description:Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50310114((E)-(4-(12-hydroxydodecylidene)-2-(hydroxymethyl)-...)
Affinity DataKi:  15nMAssay Description:Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50310128((E)-(4-(16-azidohexadecylidene)-2-(hydroxymethyl)-...)
Affinity DataKi:  16nMAssay Description:Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50310119((E)-(2-(hydroxymethyl)-5-oxo-4-(12-oxododecylidene...)
Affinity DataKi:  30nMAssay Description:Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50310122((E)-16-(5-(hydroxymethyl)-2-oxo-5-(pivaloyloxymeth...)
Affinity DataKi:  30nMAssay Description:Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50310129((E)-(4-(16-aminohexadecylidene)-2-(hydroxymethyl)-...)
Affinity DataKi:  36nMAssay Description:Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50310118((E)-(2-(hydroxymethyl)-5-oxo-4-(8-oxooctylidene)te...)
Affinity DataKi:  39nMAssay Description:Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50310117((E)-(4-(8-hydroxyhexadecylidene)-2-(hydroxymethyl)...)
Affinity DataKi:  118nMAssay Description:Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50310102((E)-(2-(hydroxymethyl)-4-(8-methoxyoctylidene)-5-o...)
Affinity DataKi:  191nMAssay Description:Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50310108((E)-(2-(hydroxymethyl)-4-(8-(methoxymethoxy)octyli...)
Affinity DataKi:  198nMAssay Description:Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50310109((E)-(2-(hydroxymethyl)-4-(8-((2-methoxyethoxy)meth...)
Affinity DataKi:  323nMAssay Description:Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50310113((E)-(2-(hydroxymethyl)-4-(8-hydroxyoctylidene)-5-o...)
Affinity DataKi:  378nMAssay Description:Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50310123((E)-methyl 8-(5-(hydroxymethyl)-2-oxo-5-(pivaloylo...)
Affinity DataKi:  533nMAssay Description:Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM445956(US10669246, Example 8 | US10968188, Example 8)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of recombinant human His-tagged c-Abl kinase assessed as luminescence incubated for 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50579414(CHEMBL4867416)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of recombinant human His-tagged c-Abl kinase assessed as luminescence incubated for 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50579413(CHEMBL4862792)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of recombinant human His-tagged c-Abl kinase assessed as luminescence incubated for 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM445952(US10669246, Example 4 | US10968188, Example 4)
Affinity DataIC50:  5.10nMAssay Description:Inhibition of recombinant human His-tagged c-Abl kinase assessed as luminescence incubated for 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50579417(CHEMBL4868871)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of recombinant human His-tagged c-Abl kinase assessed as luminescence incubated for 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM446004(US10669246, Example 55 | US10968188, Example 55)
Affinity DataIC50:  6.10nMAssay Description:Inhibition of recombinant human His-tagged c-Abl kinase assessed as luminescence incubated for 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50579418(CHEMBL4851470)
Affinity DataIC50:  7.5nMAssay Description:Inhibition of recombinant human His-tagged c-Abl kinase assessed as luminescence incubated for 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM446005(US10669246, Example 56 | US10968188, Example 56)
Affinity DataIC50:  7.60nMAssay Description:Inhibition of recombinant human His-tagged c-Abl kinase assessed as luminescence incubated for 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM446035(US10669246, Example 86 | US10968188, Example 86)
Affinity DataIC50:  8.70nMAssay Description:Inhibition of recombinant human His-tagged c-Abl kinase assessed as luminescence incubated for 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM445953(US10669246, Example 5 | US10968188, Example 5)
Affinity DataIC50:  9nMAssay Description:Inhibition of recombinant human His-tagged c-Abl kinase assessed as luminescence incubated for 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50579420(CHEMBL4874824)
Affinity DataIC50:  9.70nMAssay Description:Inhibition of recombinant human His-tagged c-Abl kinase assessed as luminescence incubated for 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50579423(CHEMBL4849019)
Affinity DataIC50:  11nMAssay Description:Inhibition of recombinant human His-tagged c-Abl kinase assessed as luminescence incubated for 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM445983(US10669246, Example 36 | US10968188, Example 36)
Affinity DataIC50:  12nMAssay Description:Inhibition of recombinant human His-tagged c-Abl kinase assessed as luminescence incubated for 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM446064(US10669246, Example 121 | US10968188, Example 121)
Affinity DataIC50:  12nMAssay Description:Inhibition of recombinant human His-tagged c-Abl kinase assessed as luminescence incubated for 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM445951(US10669246, Example 3 | US10968188, Example 3)
Affinity DataIC50:  12nMAssay Description:Inhibition of recombinant human His-tagged c-Abl kinase assessed as luminescence incubated for 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50579422(CHEMBL4853083)
Affinity DataIC50:  14nMAssay Description:Inhibition of recombinant human His-tagged c-Abl kinase assessed as luminescence incubated for 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM445949(US10669246, Example 1 | US10968188, Example 1)
Affinity DataIC50:  17nMAssay Description:Inhibition of recombinant human His-tagged c-Abl kinase assessed as luminescence incubated for 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM446044(US10669246, Example 95 | US10968188, Example 95)
Affinity DataIC50:  21nMAssay Description:Inhibition of recombinant human His-tagged c-Abl kinase assessed as luminescence incubated for 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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